Chemistry
Spectroscopy

Double beam UV-VIS photometer with temperature controlled sample holder for liquid samples. Measurement range is 190 - 1100 nm and the instrument can measure 8 samples simultaneously at 4 different temperatures in the range from 0 - 110 °C.
The spectrophotometer is capable of measuring spectra and concentration as a function of time and temperature. More information on Cary 3500 can be found here.

Double beam UV-VIS photometer


Specifications
Xenon flash lamp (250 Hz)
Scanning speed up to 150,000 nm/min.
Bandwidth 0.1 - 5.0 nm
190 - 1100 nm range
Temperature controlled multicell holder for 8 samples
Temperature control from 0 - 100 °C at max 30 °C/min.

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

Fourier transform infrared spectrometer (FTIR) that can measure in the range 7800cm-1 to 80 cm-1. The instrument has a sample compartment for gases, solids and liquids. In addition the instrument has a built-in diamond ATR module. Further information on the iS50 can be found here.

Fourier transform infrared spectrometer (FTIR)


Specifications
FT-IR
Transmission and ATR
Resolution 0.09 cm-1
Range 7800 - 80 cm-1

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

Infrared FT spectrometer for in-situ monitoring of chemistry reactions. The instrument has two ATR probes for measurements on gases or liquids. The diamond ATR probe (DiComp) measures in the range 5000 - 1428 cm-1 and the silicon ATR probe (SiComp) measures in the range 1333 - 650 cm-1. The IR probes are for real-time monitoring of IR active groups in chemical reactions at standard conditions or at elevated pressures and temperatures. Further information on the ReactIR 702L can be found here.

Infrared FT spectrometer


Specifications
FT - ATR IR
Resolution 4 cm-1
Range 4000 cm-1 - 800 cm-1
DiComp: -80 - 300 °C, 69 bar, pH 1-14
SiComp: -80 - 300 °C, 69 bar, pH 1-9

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

Single-beam fluorometer with temperature-controlled sample compartment for measurement at -25 °C to 200 °C. The instrument has an integration sphere for quantum yield measurements. The instrument is capable of time dependent measurements (TCSPC) using either a xenon flash lamp or LED source. Further information on the FluoroMax-4 can be found here. 

Single-beam fluorometer


Specifications
Xenon lamp (150 W) and xenon flash lamp (190 - 1100 nm)
Resolution 0.3 nm
Max scanning speed 80 nm/sec.
Precision ± 0.5 nm
Excitation: 200 - 980 nm
Emission: 200 - 850 nm
Bandwith: 0 - 30 nm

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

Microplate readers

Microplate reader with absorbance, fluorescence and luminescence detectors. The reader can process 6-384 well plates. Further information on  SpectraMax iD5 can be found here.

Microplate reader


Specifications
Absorbance: top/bottom read 230 - 1000 nm
Fluorescence: top/bottom read:

  • Excitation: 250 - 830 nm
  • Emission: 270 - 850 nm

Luminescence: top/bottom read 300 - 850 nm
Fluorescence polarization: top/bottom read 300 - 750 nm
Time-resolved fluorescence: Yes

  • Excitation: 350 nm
  • Emission: 450 - 750 nm

Injectors: Yes

Location
Science Institute, Askja
Manager: Jens Guðmundur Hjörleifsson
Measurement costs: Yes
Access: Contact manager

Mass spectrometers

Quadrupole mass spectrometer with electrospray ionization (ESI). Instrument for mass spectrometry on molecules with mass in the range 100 - 3000 g/mol and of picogram amount. Further information on the Compact QTOF can be found here.

Bruker Compact QTOF mass spectrometer


Specifications
Range: 100 - 3000 g/mol
Sensitivity in picogram range
Accuracy: 1 ppm
50 GBit/sec. measurement speed

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

Mass spectrometers with liquid chromatography

Tandem mass spectrometer connected to a 2D liquid chromatography system (UPLC-QQQ MS). This instrument is for quantification of biomolecules, e.g. proteins, lipids and metabolites in biosamples. Installed methods include measurements on proteins, small molecules and lipids from cells, tissues and biosamples. Further information on the Xevo TQ-XS can be found here.

Acquity Xevo TQ-XS mass spectrometer


Specifications
Range: 2 - 2048 m/z
Resolution: 1000 (FWHM)
Dynamic range: 100,000
Sampling rate: 500 Hz
Radar: Yes
MRM: Yes
ESI/UniSpray

Location
MASSHEI, Sturlugata 8
Manager: Finnur Freyr Eiríksson, Prof. Margrét Þorsteinsdóttir
Measurement costs: Yes
Access: Yes, after training. Contact managers.

Quadrupole time of flight mass spectrometer connected to a liquid chromatography system (UPLC - qTOF MS). Mass spectrometer for analysis of small molecules and relative concentration of molecules in biosamples (lipids and metabolites). Installed methods include analysis of small biomolecules and lipids (metabolomics, lipidomics etc.) from cell, tissue and biosamples.

Acquity Synapt G1 mass spectrometer


Specifications
Range: 20 - 100,000 m/z in V-mode and 20 - 16,500 m/z in W-mode
Resolution: 9,000 - 18,000 (FWHM)
Precision: 3 ppm RMS
Dynamic range: 100
Sampling rate: 20 Hz
Ion mobility: Yes
Dependent and independent data analysis: Yes
ESI

Location
MASSHEI, Sturlugata 8
Manager: Finnur Freyr Eiríksson, Prof. Margrét Þorsteinsdóttir
Measurement costs: Yes
Access: Yes, after training. Contact managers.

Quadrupole time of flight mass spectrometer connected to a liquid chromatography system (UPLC - qTOF MS). Mass spectrometer for analysis of small molecules and relative concentration of molecules in biosamples (lipids and metabolites). Installed methods include analysis on small biomolecules and lipids (metabolomics, lipidomics etc.) from cell, tissue and biosamples.

Acquity UPLC Synapt G2 mass spectrometer


Specifications
Range: 20 - 100,000 m/z in V-mode and 20 - 32,000 m/z in W-mode
Resolution: 100,000 - 40,000 (FWHM)
Precision: 1 ppm RMS
Dynamic range: 10,000
Sampling rate: 20 Hz
Ion mobility: Yes
Dependent and independent data analysis: Yes
ESI

Location
MASSHEI, Sturlugata 8
Manager: Óttar Rolfsson, Finnur Freyr Eiríksson
Measurement costs: Yes
Access: Yes, after training. Contact managers.

Quadrupole time of flight mass spectrometer connected to a nano- to micro-scale chromatography system. The instrument is an updated version of the Synapt G2 mass spectrometer designed for detection of proteins and small molecules. Installed methods include analysis of proteins, small molecules and lipids (metabolomics, lipidomics etc.) from cells, tissue and biosamples.

Acquity M-Class UPLC Synapt XS mass spectrometer


Specifications
Range: 20 - 100,000 m/z in V-mode and 20 - 32,000 m/z in W-mode
Resolution: 12,500 - 80,000 (FWHM)
Precision: 1 ppm RMS
Dynamic range: 10,000
Sampling rate: 20 Hz
Ion mobility: Yes
SONAR: Yes
Dependent and independent data analysis: Yes
ESI/nanoflow ESI/DESI imaging

Location
MASSHEI, Sturlugata 8
Manager: Óttar Rolfsson, Finnur Freyr Eiríksson
Measurement costs: Yes
Access: Yes, after training. Contact managers.

Mass spectrometers for imaging

Quadrupole time of flight mass spectrometer connected to a nano- to micro-scale chromatography system (UPLC-qTOF MS). A mass spectrometer designed for imaging of the spatial distribution of molecules in samples. Installed methods include analysis of proteins, small molecules and lipids (metabolomics, lipidomics etc.) from cells, tissue and biosamples.

Synapt XS DESI mass spectrometer

Specifications
Range: 20 - 100,000 m/z in V-mode and 20 - 32,000 m/z in W-mode
Resolution: 12,500 - 80,000 (FWHM)
Precision: 1 ppm RMS
Dynamic range: 10,000
Sampling rate: 20 Hz
Ion mobility: Yes
SONAR: Yes
Dependent and independent data analysis: Yes
ESI/nanoflow ESI/DESI imaging

Location
MASSHEI, Sturlugata 8
Manager: Óttar Rolfsson, Finnur Freyr Eiríksson
Measurement costs: Yes
Access: Yes, after training. Contact managers.

Liquid handling automation

Liquid handling robot for various handling of biosamples and preparations for mass spectrometry.

Tecan EVO 150 + Resolvex A200 Robot

Specifications
Phase separations: Yes
Liquid-liquid extractions: Yes
Protein precipitation: Yes

Location
MASSHEI, Sturlugata 8
Manager: Finnur Freyr Eiríksson, Prof. Margrét Þorsteinsdóttir
Measurement costs: Yes
Access: Yes, after training. Contact managers.

Magnetic resonance

600 MHz nuclear magnetic resonance (NMR) instrument with three-channel 5 mm TXI probe and automatic sample holder for 60 samples. The device can measure spectra for protons (1H), carbon (13C) and nitrogen (15N). Two-dimensional and three-dimensional spectra can also be measured, e.g. COZY or HSQC. Further information on TXI Probes.

Bruler Avance 600

 

Specifications
600 MHz spectrometer with three-channel probe for 1H, 13C and 15N.
Sample changer for 60 samples.
Sample temperature control from -40 °C to 150 °C

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

 

400 MHz NMR spectrometer with a dual channel SmartProbe and automatic sample changer. The spectrometer can measure spectra for protons (1H), carbons (13C), fluorine (19F), nitrogen(15N) and phosphorus(31P). Several 2D spectra can also be measured, e.g. COSY and HSQC. Further details on the SmartProbe can be found here.

Bruker Avance 400 NMR spectrometer


Specifications
400 MHz with two rf. channels
Sample changer for 60 samples
Temperature control from -40 °C to RT

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

9.5 GHz electron spin resonance spectrometer for measurement of liquid and solid samples. The sample temperature can be controlled from -170 °C to 200 °C.

Magnettech MiniScope MS200 EPR spectrometer


Specifications
9.5 GHz
Magnetic field: 5 - 650 mT
Resolution: 0.03 µT
Scanning speed: 0 - 645 mT
Scanning resolution: 120,000 points
Microwave source: 1 µW - 100 mW
Sensitivity: 8x109 spins/0.1 mT

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

80 MHz benchtop NMR spectrometer for measurement of proton(1H), fluorine(19F) and carbon(13C) spectra. The instrument can also measure COSY, HSQC and HMBC 2D spectra.

Spinsolve 80 Carbon NMR spectrometer


Specifications
80 MHz, 2 Tesla
Resolution: 1H linewidth: 50% <0.5 Hz, 0.55% <20 Hz
Sensitivity: >200:1 for 1% ethylbenzene
Temperature controller for sample

Location
Hagi
Manager: Árni Þorgrímur Kristjánsson
Measurement costs: Yes
Access: Contact manager

Materials testing

Instrument for simultaneous differential scanning calorimetry (DSC) and thermal gravimetric analysis (TGA). A quadrupole mass spectrometer is connected to the instrument for analysis of compounds evaporating from sample upon heating. Further information on the SDT650 can be found here.

TA Instruments SDT650 TGA-DSC Thermal Analyzer

Specifications
Temperature range of furnace: Room temperature to 1500 °C.
  at a rate of 0.1 to 100 °C/min.
Temperature accuracy: ±1 °C
Weight accuracy: ± 0.5%
Max sample weight 200 mg
Range of mass spectrometer: 1 - 300 g/mol
Resolution of mass spectrometer: >0.5 g/mol
  sensitivity <100 ppb

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

Instrument for measuring the flow and deformation of materials.

Anton Paar MCR 302 rheometer

Specifications
Torque: 0.5 nNm - 230 mNm
Rotational range: 0.05 µrad - ∞
Angular frequency: 1x10-7 to 628 rad/sec.
Angular speed: 0 to 314 rad/sec.
Temperature: -160 °C to 1000 °C
Pressure: up to 1000 bar

Location
Science Institute, Dunhagi 3
Manager: Prof. Krishna Damodaran
Measurement costs: Yes
Access: Contact manager

Biophysical analysis

Microscale thermophoresis instrument for measurement of interaction between biomolecules. The directed movement of molecules is detected using the intrinsic tryptophan fluorescence.

Microscale thermophoresis instrument

 

Specifications
Number of samples: 16
Concentration range: 10 nM - mM
Sample volume: < 4 µL
Temperature: 22 °C to 45 °C

Location
Science Institute, Askja
Manager: Jens Guðmundur Hjörleifsson
Measurement costs: Yes
Access: Contact manager

Liquid chromatography

Gel permeation chromatography (GPC) system with light scattering detector (MALS), refractive index detector (RI) and viscocity meter. With appropriate columns this instrument is for analysis of molecular weight, size and shape of synthetic- and bio-polymers. Sample can be measured in a broad range of temperatures.

Wyatt GPC System


Specifications
MALS detector:
  Range: 200 Da - 100 MDa
  or molecule diameter of 10 nm to 300 nm
  Sensitivity: 300 ng bovine serum albumin in PBS
  Temperature control from -15 °C to 150 °C (±0.1 °C)
Refractometer:
  Range: -0.0047 to +0.0047 RIU
  Sensitivity: ±7.5x10-10 RIU
  Temperature: 4 °C to 65 °C
Viscometer:
  Sensitivity: 100 ng 100 kDa polystyrene in THF
  Temperature: 4 °C to 70 °C
HPLC:
  0.001 - 10 mL/min.
  max 600 bar
  Column temperature: Room temperature to 85 °C
  UV-VIS: 190 - 600 nm

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

Analytical high performance liquid chromatography (HPLC) system with UV-VIS detector. The instrument is for analysis of microliter sample volumes.

Agilent 1200 HPLC System


Specifications
UV-VIS deuterium and tungsten lamps
DAD detector (190 - 950 nm)
100 µL sample loop
Binary SL high pressure pump
Degasser
Temperature controller for columns

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

Analytical/preparative high performance liquid chromatography (HPLC) system with UV-VIS detector. The instrument is for analysis of microliter to milliliter sample volumes. The system has an automatic sample injector and fraction collector.

Agilent 1290 Infinity II HPLC System


Specifications
UV-VIS (190 - 950 nm) deuterium and tungsten lamps
DAD WR detector 190 - 950 nm
400 µL and 10 mL sample loops
Binary prep. high pressure pump
Temperature controller for columns

Location
Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

Analytical high performance liquid chromatography (HPLC) system with UV DAD- and quadrupole mass detectors.
This system is for qualitiative and quantitative analysis of small organic and inorganic molecules and polymers. The UV/VIS- and mass spectrum for the separated compounds are simultaneously measured, assisting the analysis of complicated multi-component samples.

Waters, Arc Premier HPLC system

 

Specifications

High pressure liquid pump:
Binary pump for four solvents in combination of two. Maximum pressure 650 bar and up to 5.0 mL/min flow rate.
Sample manager:
Up to 48 samples in 2 mL vials and temperature control in the range of 4.0 to 40.0 °C. 80 µL sample loop.
Column compartment for up to 4 columns and temperature control in the range of 4.0 to 90 °C.
UV-VIS spectrometer:
PDA spectrometer with 512 diodes. Wavelength range of 190 to 800 nm and 1.2 nm bandwidth.
Mass spectrometer:
Quadrupole mass detector with ESI source. Mass range is 30 to 1250 m/z for both
positive and negative ion modes. Accuracy better than ±0.2 Da and resolution 0.7 Da.
 

Location

Science Institute, Dunhagi 3
Manager: Gunnar W. Reginsson
Measurement costs: Yes
Access: Contact manager

Liquid chromatography system for purification of proteins, peptides and nucleic acids. Easy to operate and designed for purification by hydrophobicity, ion exchange and gel filtration Sample size can be from microgram to grams. Further information on the ÄKTA pure can be found here.

ÄKTA pure HPLC system


Specifications
UV-VIS (190 - 700 nm)
Simultaneous measurement of 3 wavelengths
Max pressure 20 MPa
Flow 0.01 - 25 mL/min.

Location
Science Institute, Askja
Manager: Pétur Orri Heiðarsson
Measurement costs: Yes
Access: Contact manager

Analytical high performance liquid chromatography (HPLC) system with UV-VIS detector, fluorescence detector, fraction collector and column heater. The high pressure pump is quaternary and can mix 4 solvents with gradients. The fraction collector can collect up to 216 individual fractions in one run. The instrument is for general chromatography applications using various columns.

Agilent 1260 Infinity II HPLC system


Specifications
DAD WR detector (190 - 950 nm)
Fluorescence:
  Excitation: 200 - 1200 nm
  Emission: 200 - 1200 nm
  Bandwidth: 20 nm
Sample loops: 50, 100 and 200 µL
Temperature controler for 10 - 85 °C
Fraction collector for up to 216 fractions

Location
Science Institute, Askja
Manager: Pétur Orri Heiðarsson
Measurement costs: Yes
Access: Contact manager

High pressure chromatography system with ultraviolet detector (TUV), fluorescence detector (FLR) og light refraction detector (RID). This system is for analysis of large molecules in organic solvents and in solvents of high ion strength. Further information on the Acquity Arc Bio can be found here.

Acquity Arc Bio HPLC system


Specifications
TUD detector (190 - 700 nm)
FLR detector:
  Excitation: 200 - 890 nm
  Emission: 210 - 900 nm
  Bandwidth: 20 nm
RID detector:
  Temperature control 30 - 150 °C
  Rate 80 p/sec.

Location
Hagi
Manager: Árni Þorgrímur Kristjánsson
Measurement costs: Yes
Access: Contact manager

Flash chromatography system with UV-VIS detector and evaporative light scattering detector (ELSD) for detection of compounds without chromophores. This system is for separation, collection and analysis of multicomponent solutions of biomolecular samples. The instrument has automatic sample injection. Further information on the PuriFlash 5.250 can be found here.

Puriflash 5.250 HPLC system


Specifications
UV-VIS detector (200 - 800 nm)
Scanning and single wavelength detection
ELSD detector

Location
Hagi
Manager: Árni Þorgrímur Kristjánsson
Measurement costs: Yes
Access: Contact manager

X-ray crystallography

X-ray diffractometer for analysis of single crystals and determination of atomic structure. Further information on the Bruker D8 Venture can be found here.

Bruker D8 Venture Single Crystal X-ray Diffractometer


Specifications
IµS microfocus Mo and Cu X-ray sources. 0 - 50 kV; 0 - 2 mA
Photon 100 detector
Temperature control for samples 100 - 400 Kelvin or 30 - 300 Kelvin with N-Helix

Location
Science Institute, Dunhagi 3
Manager: Prof. Krishna Damodaran
Measurement costs: Yes
Access: Contact manager

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