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Zophonías Oddur Jónsson - Professor
–
School of Engineering and Natural Sciences
Zophonías Oddur Jónsson
Íslenska
Professor
Professor of molecular genetics
Location
Askja / N-345
Phone
5254084
Email
zjons [at] hi.is
Unit
Faculty of Life and Environmental Sciences
Website
http://www.hi.is/~zjons
ORCID site
https://orcid.org/0000-0001-5798-9647
Research portal – Zophonías Oddur Jónsson
Under construction throughout the autumn semester 2023
Courses 2023 - 2024
LÆK028F - Stem cells and differentiation
LÍF644M - Molecular Genetics
LÍF614M - Cell Biology II
LÍF223F - Research in molecular biology and biochemistry
LÍF315G - Cell Biology
LÍF523G - Methods in Molecular Biology
LÍF118F - Methods in Molecular Biology
LÍF109G - Genetics
LÍF540G - Genetics B
LÍF533M - Microbiology II
LÍF534M - Microbial biotechnology
ILT002F - Prerequisite studies in Genetics
Collaboration
Wohlschlegel
,
James A. Wohlschlegel
,
James A. Wohlschlegel
Ólafur S. Andrésson
,
Ólafur S. Andrésson
,
Ólafur S. Andrésson
Education
1998
,
Ph.D.
,
University of Zurich
,
Molecular Biology
1994
,
Meistarapróf
,
University of Iceland
,
Molecular Biology
1991
,
BS
,
University of Iceland
,
Biology
1986
,
Stúdentspróf
,
Menntaskólinn í Reykjavík
,
Professional Experience
2013 -
,
Professor,
University of Iceland
2005 -
2013,
Associate Professor,
University of Iceland
2003 -
2004,
Project Manager,
Institute of Biology
2003 -
2004,
Associate Professor,
University of Iceland
1999 -
2003,
Postdoc,
Harvard Medical School
1998 -
1999,
Postdoc,
Institut für Veterinärbiochemie, Universität Zürich-Irchel
Published works
2023
Rapid and biased evolution of canalization during adaptive divergence revealed by dominance in gene expression variability during Arctic charr early development
Communications Biology
Genome‐phenotype‐environment associations identify signatures of selection in a panmictic population of threespine stickleback
Molecular Ecology
Insights into Early Ontogenesis of Salmo salar: RNA Extraction, Housekeeping Gene Validation and Transcriptional Expression of Important Primordial Germ Cell and Sex-Determination Genes
Animals
2022
DNA methylation differences during development distinguish sympatric morphs of Arctic charr (Salvelinus alpinus)
Molecular Ecology
2021
RAD sequencing of common whelk, Buccinum undatum, reveals fine‐scale population structuring in Europe and cryptic speciation within the North Atlantic
Ecology and Evolution
2020
Differences among families in craniofacial shape at early life-stages of Arctic charr (Salvelinus alpinus)
BMC developmental biology
2019
The mitochondrial genome of common whelk Buccinum undatum (Neogastropoda: Buccinidae)
Mitochondrial DNA Part B
Extensive genetic differentiation between recently evolved sympatric Arctic charr morphs
Ecology and Evolution
Gene expression in the phenotypically plastic Arctic charr (Salvelinus alpinus): A focus on growth and ossification at early stages of development
Evol. Dev.
2018
Extensive genetic divergence between recently evolved sympatric Arctic charr morphs
bioRxiv
Shell morphology and color of the subtidal whelk Buccinum undatum exhibit fine-scaled spatial patterns
Ecol Evol
Differential gene expression during early development in recently evolved and sympatric Arctic charr morphs
PeerJ
Inducers of salmon innate immunity: An in vitro and in vivo approach
Fish Shellfish Immunol.
2016
Investigation of the effects of estrogen on skeletal gene expression during zebrafish larval head development
PeerJ
2015
Bones in motion: Ontogeny of craniofacial development in sympatric arctic charr morphs
Dev. Dyn.
High-throughput sequencing in studies of lichen population biology
Recent advances in lichenology
The developmental transcriptome of contrasting Arctic charr ( Salvelinus alpinus) morphs
F1000Res
Differential expression of the aryl hydrocarbon receptor pathway associates with craniofacial polymorphism in sympatric Arctic charr
Evodevo
2014
Transcriptional dynamics of a conserved gene expression network associated with craniofacial divergence in Arctic charr
Evodevo
Patterns of miRNA expression in Arctic charr development
PLoS ONE
Insect stage-specific receptor adenylate cyclases are localized to distinct subdomains of the Trypanosoma brucei Flagellar membrane
Eukaryotic Cell
2013
Validation of reference genes for expression studies during craniofacial development in arctic charr
PLoS ONE
Divergence and molecular variation in common whelk Buccinum undatum (Gastropoda: Buccinidae) in Iceland: a trans-Atlantic comparison
Biological Journal of the Linnean Society
2012
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity
Science
The acute phase response of cod (Gadus morhua L.): expression of immune response genes
Fish Shellfish Immunol.
Mitochondrial genomes from the lichenized fungi Peltigera membranacea and Peltigera malacea: features and phylogeny
Fungal Biol
2011
A Dbf4 mutant contributes to bypassing the Rad53-mediated block of origins of replication in response to genotoxic stress
J. Biol. Chem.
The acute phase response of Atlantic cod (Gadus morhua): humoral and cellular response
Fish Shellfish Immunol.
Novel core promoter elements and a cognate transcription factor in the divergent unicellular eukaryote Trichomonas vaginalis
Mol. Cell. Biol.
Independent analysis of the flagellum surface and matrix proteomes provides insight into flagellum signaling in mammalian-infectious Trypanosoma brucei
Mol. Cell Proteomics
2010
Damage-induced phosphorylation of Sld3 is important to block late origin firing
Nature
2009
Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members
Genes Dev.
Human-specific transcriptional regulation of CNS development genes by FOXP2
Nature
Cloning and heterologous transcription of a polyketide synthase gene from the lichen Solorina crocea
Mycol. Res.
Isolation of two C-reactive protein homologues from cod (Gadus morhua L.) serum
Fish Shellfish Immunol.
2004
Rvb1/Rvb2 (TIP48/TIP49) are required to recruit Arp5p into a functional Ino80 chromatin remodeling complex
FASEB JOURNAL
Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complex
Mol. Cell
2003
Identification and nucleotide sequence analysis of a cryptic plasmid, pRM21, from Rhodothermus marinus
Plasmid
A DNA ligase from the psychrophile Pseudoalteromonas haloplanktis gives insights into the adaptation of proteins to low temperatures
European Journal of Biochemistry
Small RNAs with imperfect match to endogenous mRNA repress translation
Journal of Biological Chemistry
Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells
J. Biol. Chem.
Elongation by RNA polymerase II on chromatin templates requires topoisomerase activity
Nucleic Acids Res.
Identification and nucleotide sequence analysis of a cryptic plasmid, pRM21, from Rhodothermus marinus
Plasmid
2002
RVB proteins, AAA plus ATPases that are an essential component of the Ino80 chromatin remodeling complex
FASEB JOURNAL
2001
A coordinated interplay: proteins with multiple functions in DNA replication, DNA repair, cell cycle/checkpoint control, and transcription
Prog. Nucleic Acid Res. Mol. Biol.
In eukaryotic flap endonuclease 1, the C terminus is essential for substrate binding
J. Biol. Chem.
Rvb1p/Rvb2p, implicated in cell transformation by Myc and in DNA repair and apoptosis, is an ATP dependent chromatin remodeling factor
FASEB JOURNAL
Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes
J. Biol. Chem.
2000
A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage
Mol. Cell. Biol.
Optimised ligation of oligonucleotides by thermal ligases: comparison of Thermus scotoductus and Rhodothermus marinus DNA ligases to other thermophilic ligases
Nucleic Acids Res.
A CAF-1/PCNA mediated chromatin assembly pathway-Importance for DNA damage sensing and processing
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
The PCNA from Thermococcus fumicolans functionally interacts with DNA polymerase delta
Biochem. Biophys. Res. Commun.
A coordinated interplay: Proteins with multiple functions in DNA replication, DNA repair, cell cycle/checkpoint control, and transcription
Progress in nucleic acid research and molecular biology
A direct interaction between proliferating cell nuclear antigen (PCNA) and Cdk2 targets PCNA-interacting proteins for phosphorylation
J. Biol. Chem.
A DNA ligase from the psychrophile Pseudoalteromonas haloplanktis gives insights into the adaptation of proteins to low temperatures
Eur. J. Biochem.
1999
Functional analysis of DNA replication accessory proteins
Eukaryotic DNA replication, ed Cotterill S.(Oxford University Press, Oxford, UK)
Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon
J. Biol. Chem.
Dual mode of interaction of DNA polymerase epsilon with proliferating cell nuclear antigen in primer binding and DNA synthesis
J. Mol. Biol.
1998
The solution structure of functionally active human proliferating cell nuclear antigen determined by small-angle neutron scattering
J. Mol. Biol.
Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen
EMBO J.
1997
Replication factor C interacts with the C-terminal side of proliferating cell nuclear antigen
J. Biol. Chem.
Proliferating cell nuclear antigen: more than a clamp for DNA polymerases
Bioessays
1996
Interaction studies between the p21Cip1/Waf1 cyclin-dependent kinase inhibitor and proliferating cell nuclear antigen (PCNA) by surface plasmon resonance
FEBS Lett.
1995
Cloning and sequence analysis of the DNA ligase-encoding gene of Rhodothermus marinus, and overproduction, purification and characterization of two thermophilic DNA ligases
Gene
Tyrosine 114 is essential for the trimeric structure and the functional activities of human proliferating cell nuclear antigen
EMBO J.
1994
Sequence of the DNA ligase-encoding gene from Thermus scotoductus and conserved motifs in DNA ligases
Gene
Keywords for Specialisation:
Gene regulation in yeast and arctic charr
DNA replication
Chromatin remodeling
MiRNA
Epigenetics
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