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Forsíða

Zophonías Oddur Jónsson - Professor

Zophonías Oddur Jónsson

–

School of Engineering and Natural Sciences

Zophonías Oddur Jónsson

Professor

Professor of molecular genetics

Location
Askja / N-345
Phone
5254084
Email
zjons [at] hi.is

Unit
Faculty of Life and Environmental Sciences
Website
http://www.hi.is/~zjons

ORCID site
https://orcid.org/0000-0001-5798-9647
Research portal – Zophonías Oddur Jónsson
Under construction throughout the autumn semester 2023

Published works

2023

Insights into Early Ontogenesis of Salmo salar: RNA Extraction, Housekeeping Gene Validation and Transcriptional Expression of Important Primordial Germ Cell and Sex-Determination GenesAnimals
Genome‐phenotype‐environment associations identify signatures of selection in a panmictic population of threespine sticklebackMolecular Ecology

2022

DNA methylation differences during development distinguish sympatric morphs of Arctic charr ( Salvelinus alpinus )Molecular Ecology

2021

RAD sequencing of common whelk, Buccinum undatum, reveals fine‐scale population structuring in Europe and cryptic speciation within the North AtlanticEcology and Evolution

2020

Differences among families in craniofacial shape at early life-stages of Arctic charr (Salvelinus alpinus)BMC developmental biology

2019

The mitochondrial genome of common whelk Buccinum undatum (Neogastropoda: Buccinidae)Mitochondrial DNA Part B
Extensive genetic differentiation between recently evolved sympatric Arctic charr morphsEcology and Evolution
Gene expression in the phenotypically plastic Arctic charr (Salvelinus alpinus): A focus on growth and ossification at early stages of developmentEvol. Dev.

2018

Extensive genetic divergence between recently evolved sympatric Arctic charr morphsbioRxiv
Shell morphology and color of the subtidal whelk Buccinum undatum exhibit fine-scaled spatial patternsEcol Evol
Differential gene expression during early development in recently evolved and sympatric Arctic charr morphsPeerJ
Inducers of salmon innate immunity: An in vitro and in vivo approachFish Shellfish Immunol.

2016

Investigation of the effects of estrogen on skeletal gene expression during zebrafish larval head developmentPeerJ

2015

Bones in motion: Ontogeny of craniofacial development in sympatric arctic charr morphsDev. Dyn.
The developmental transcriptome of contrasting Arctic charr ( Salvelinus alpinus) morphsF1000Res
High-throughput sequencing in studies of lichen population biologyRecent advances in lichenology
Differential expression of the aryl hydrocarbon receptor pathway associates with craniofacial polymorphism in sympatric Arctic charrEvodevo

2014

Transcriptional dynamics of a conserved gene expression network associated with craniofacial divergence in Arctic charrEvodevo
Insect stage-specific receptor adenylate cyclases are localized to distinct subdomains of the Trypanosoma brucei Flagellar membraneEukaryotic Cell
Patterns of miRNA expression in Arctic charr developmentPLoS ONE

2013

Validation of reference genes for expression studies during craniofacial development in arctic charrPLoS ONE
Divergence and molecular variation in common whelk Buccinum undatum (Gastropoda: Buccinidae) in Iceland: a trans-Atlantic comparisonBiological Journal of the Linnean Society

2012

The acute phase response of cod (Gadus morhua L.): expression of immune response genesFish Shellfish Immunol.
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrityScience
Mitochondrial genomes from the lichenized fungi Peltigera membranacea and Peltigera malacea: features and phylogenyFungal Biol

2011

A Dbf4 mutant contributes to bypassing the Rad53-mediated block of origins of replication in response to genotoxic stressJ. Biol. Chem.
The acute phase response of Atlantic cod (Gadus morhua): humoral and cellular responseFish Shellfish Immunol.
Novel core promoter elements and a cognate transcription factor in the divergent unicellular eukaryote Trichomonas vaginalisMol. Cell. Biol.
Independent analysis of the flagellum surface and matrix proteomes provides insight into flagellum signaling in mammalian-infectious Trypanosoma bruceiMol. Cell Proteomics

2010

Damage-induced phosphorylation of Sld3 is important to block late origin firingNature

2009

Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family membersGenes Dev.
Cloning and heterologous transcription of a polyketide synthase gene from the lichen Solorina croceaMycol. Res.
Human-specific transcriptional regulation of CNS development genes by FOXP2Nature
Isolation of two C-reactive protein homologues from cod (Gadus morhua L.) serumFish Shellfish Immunol.

2004

Rvb1/Rvb2 (TIP48/TIP49) are required to recruit Arp5p into a functional Ino80 chromatin remodeling complexFASEB JOURNAL
Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complexMol. Cell

2003

Identification and nucleotide sequence analysis of a cryptic plasmid, pRM21, from Rhodothermus marinusPlasmid
Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cellsJ. Biol. Chem.
Elongation by RNA polymerase II on chromatin templates requires topoisomerase activityNucleic Acids Res.
Identification and nucleotide sequence analysis of a cryptic plasmid, pRM21, from Rhodothermus marinusPlasmid
A DNA ligase from the psychrophile Pseudoalteromonas haloplanktis gives insights into the adaptation of proteins to low temperaturesEuropean Journal of Biochemistry
Small RNAs with imperfect match to endogenous mRNA repress translationJournal of Biological Chemistry

2002

RVB proteins, AAA plus ATPases that are an essential component of the Ino80 chromatin remodeling complexFASEB JOURNAL

2001

Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genesJ. Biol. Chem.
In eukaryotic flap endonuclease 1, the C terminus is essential for substrate bindingJ. Biol. Chem.
A coordinated interplay: proteins with multiple functions in DNA replication, DNA repair, cell cycle/checkpoint control, and transcriptionProg. Nucleic Acid Res. Mol. Biol.
Rvb1p/Rvb2p, implicated in cell transformation by Myc and in DNA repair and apoptosis, is an ATP dependent chromatin remodeling factorFASEB JOURNAL

2000

A DNA ligase from the psychrophile Pseudoalteromonas haloplanktis gives insights into the adaptation of proteins to low temperaturesEur. J. Biochem.
A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damageMol. Cell. Biol.
Optimised ligation of oligonucleotides by thermal ligases: comparison of Thermus scotoductus and Rhodothermus marinus DNA ligases to other thermophilic ligasesNucleic Acids Res.
A coordinated interplay: Proteins with multiple functions in DNA replication, DNA repair, cell cycle/checkpoint control, and transcriptionProgress in nucleic acid research and molecular biology
A CAF-1/PCNA mediated chromatin assembly pathway-Importance for DNA damage sensing and processingCOLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
The PCNA from Thermococcus fumicolans functionally interacts with DNA polymerase deltaBiochem. Biophys. Res. Commun.
A direct interaction between proliferating cell nuclear antigen (PCNA) and Cdk2 targets PCNA-interacting proteins for phosphorylationJ. Biol. Chem.

1999

Dual mode of interaction of DNA polymerase epsilon with proliferating cell nuclear antigen in primer binding and DNA synthesisJ. Mol. Biol.
Functional analysis of DNA replication accessory proteinsEukaryotic DNA replication, ed Cotterill S.(Oxford University Press, Oxford, UK)
Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilonJ. Biol. Chem.

1998

The solution structure of functionally active human proliferating cell nuclear antigen determined by small-angle neutron scatteringJ. Mol. Biol.
Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigenEMBO J.

1997

Proliferating cell nuclear antigen: more than a clamp for DNA polymerasesBioessays
Replication factor C interacts with the C-terminal side of proliferating cell nuclear antigenJ. Biol. Chem.

1996

Interaction studies between the p21Cip1/Waf1 cyclin-dependent kinase inhibitor and proliferating cell nuclear antigen (PCNA) by surface plasmon resonanceFEBS Lett.

1995

Cloning and sequence analysis of the DNA ligase-encoding gene of Rhodothermus marinus, and overproduction, purification and characterization of two thermophilic DNA ligasesGene
Tyrosine 114 is essential for the trimeric structure and the functional activities of human proliferating cell nuclear antigenEMBO J.

1994

Sequence of the DNA ligase-encoding gene from Thermus scotoductus and conserved motifs in DNA ligasesGene

Keywords for Specialisation:

Gene regulation in yeast and arctic charr

DNA replication

Chromatin remodeling