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Þorsteinn Loftsson - Professor Emeritus
–
School of Health Sciences
Þorsteinn Loftsson
Íslenska
Professor Emeritus
Location
Hagi / Ha-313
Phone
525 - 4464
Email
thorstlo [at] hi.is
Unit
Faculty of Pharmaceutical Sciences
Published Work
Þorsteinn Loftsson - published work
Curriculum Vitae
Þorsteinn Loftsson - Curriculum Vitae
ORCID site
https://orcid.org/0000-0002-9439-1553
Research portal – Þorsteinn Loftsson
Collaboration
Lipid Pharmaceuticals, Reykjavik, Iceland.
,
Lipid Pharmaceuticals, Reykjavik, Iceland.
Oculis ehf., Reykjavik, Iceland.
,
Oculis ehf., Reykjavik, Iceland.
Prof. Einar Stefánsson
,
Dept. of Medicine, University of Iceland.
Education
0
,
Ph.D.
,
University of Kansas
,
Ph.D.
0
,
MS
,
University of Kansas
,
MS
0
,
MS
,
University of Copenhagen
,
M.S. Pharm. degree
Professional Experience
1986 -
,
Professor of Physical Pharmacy,
University of Iceland in Reykjavik, Iceland
1983 -
1985,
Associate Professor,
University of Iceland
1979 -
1983,
Assistant Professor,
University of Iceland
Published works
2024
The application of cyclodextrins in drug solubilization and stabilization of nanoparticles for drug delivery and biomedical applications
International Journal of Pharmaceutics
Aqueous eye drop formulations
Annales Pharmaceutiques Francaises
Drug-like properties of tyrosine kinase inhibitors in ophthalmology
International Journal of Pharmaceutics
Drug-like properties and topical delivery of rapalogs and tacrolimus in ophthalmology
Journal of Drug Delivery Science and Technology
New Improved cGMP Analogues to Target Rod Photoreceptor Degeneration
Journal of Medicinal Chemistry
2023
Topical treatment of diabetic macular edema using dexamethasone ophthalmic suspension
Acta Ophthalmologica
Celecoxib/Cyclodextrin Eye Drop Microsuspensions
Pharmaceutics
Topical dexamethasone delivery to the retina
Journal of Drug Delivery Science and Technology
Anomalous Properties of Cyclodextrins and Their Complexes in Aqueous Solutions
Materials
A promising synthetic citric crosslinked β-cyclodextrin derivative for antifungal drugs
International Journal of Pharmaceutics
Crystal Modifications of a Cyclic Guanosine Phosphorothioate Analogue, a Drug Candidate for Retinal Neurodegenerations
ChemistryOpen
Tacrolimus/hydroxypropyl-β-cyclodextrin-loaded nanoemulsions stabilized by Zein-Soluplus® nanoparticles for retinal diseases
Journal of Drug Delivery Science and Technology
Voriconazole Eye Drops
International Journal of Molecular Sciences
2022
Physicochemical and Stability Evaluation of Topical Niosomal Encapsulating Fosinopril/γ-Cyclodextrin Complex for Ocular Delivery
Pharmaceutics
Angiotensin converting enzyme inhibitors/cyclodextrin inclusion complexes
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrins and Drug Membrane Permeation: Thermodynamic Considerations
Journal of Pharmaceutical Sciences
Stabilization and solubilization of difluprednate in aqueous cyclodextrin solution and its characterization for ophthalmic delivery
Journal of Drug Delivery Science and Technology
Aqueous Prostaglandin Eye Drop Formulations
Pharmaceutics
Self-assembled γ-cyclodextrin as nanocarriers for enhanced ocular drug bioavailability
International Journal of Pharmaceutics
Structural Characterization Study of a Lipid Nanocapsule Formulation Intended for Drug Delivery Applications Using Small-Angle Scattering Techniques
Molecular Pharmaceutics
Development of Fenofibrate/Randomly Methylated β-Cyclodextrin-Loaded Eudragit® RL 100 Nanoparticles for Ocular Delivery
Molecules
Topical drug delivery to the retina
Expert Opinion on Drug Delivery
Preformulation studies of dovitinib free base
International Journal of Pharmaceutics
Topical noninvasive retinal drug delivery of a tyrosine kinase inhibitor
Acta Ophthalmologica
A Current Overview of Cyclodextrin-Based Nanocarriers for Enhanced Antifungal Delivery
Pharmaceuticals
Integration of cyclodextrins and associated toxicities
Carbohydrate Polymers
2021
Angiotensin Receptor Blockers in cyclodextrin nanoparticle eye drops
Acta Ophthalmologica
Topical drug delivery to the posterior segment of the eye: Thermodynamic considerations
International Journal of Pharmaceutics
Aqueous eye drops containing drug/cyclodextrin nanoparticles deliver therapeutic drug concentrations to both anterior and posterior segment
Acta Ophthalmologica
Age-related ocular conditions
International Journal of Pharmaceutics
1,4-Benzodiazepines: Chemical stability and cyclodextrin solubilization
Journal of Drug Delivery Science and Technology
Effect of Soluplus
®
on γ-cyclodextrin solubilization of irbesartan and candesartan and their nanoaggregates formation
Pharmaceutical Development and Technology
Bio-distribution and pharmacokinetics of topically administered γ-cyclodextrin based eye drops in rabbits
Pharmaceuticals
Cyclodextrin-based formulation of carbonic anhydrase inhibitors for ocular delivery – A review
International Journal of Pharmaceutics
Solubility and stability of cediranib maleate
Journal of Drug Delivery Science and Technology
Formulation development and upscaling of lipid nanocapsules as a drug delivery system for a novel cyclic GMP analogue intended for retinal drug delivery
International Journal of Pharmaceutics
Cytotoxicity of β-Cyclodextrins in Retinal Explants for Intravitreal Drug Formulations
Molecules
Aggregate Determination by Permeation Technique
Effect of salt formation on γ-cyclodextrin solubilization of irbesartan and candesartan and the chemical stability of their ternary complexes
Journal of Drug Delivery Science and Technology
Cyclodextrins in parenteral formulations
Journal of Pharmaceutical Sciences
2020
Free Fatty Acids from Fish Oil Inactivate SARS-CoV-2
Journal of SARS-CoV-2 and Coronavirus Disease
In Vitro and Ex Vivo Evaluation of Nepafenac-Based Cyclodextrin Microparticles for Treatment of Eye Inflammation
Nanomaterials
Solubilization and in vitro permeation of dovitinib/cyclodextrin complexes and their aggregates
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Aqueous solubility of kinase inhibitors
Journal of Drug Delivery Science and Technology
Characterization and Evaluation of Ternary Complexes of Ascorbic Acid with γ-Cyclodextrin and Poly(vinyl Alcohol)
International Journal of Molecular Sciences
Can postoperative dexamethasone nanoparticle eye drops replace mitomycin C in trabeculectomy?
Acta Ophthalmologica
Aqueous solubility of kinase inhibitors
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Self-assembly of cyclodextrin complexes: detection, obstacles and benefits
Pharmazie
Poorly soluble drugs
International Journal of Pharmaceutics
Effect of porcine pancreatic α-amylase on dexamethasone release from aqueous solution containing natural γ-cyclodextrin
International Journal of Pharmaceutics
Stability characterization, kinetics and mechanism of tacrolimus degradation in cyclodextrin solutions
International Journal of Pharmaceutics
Antifungal activity of econazole nitrate/cyclodextrin complex: Effect of pH and formation of complex aggregates
International Journal of Pharmaceutics
Aqueous solubility of kinase inhibitors
Journal of Drug Delivery Science and Technology
2019
Drug delivery to retinal photoreceptors
Drug Discovery Today
Nepafenac-Loaded Cyclodextrin/Polymer Nanoaggregates: A New Approach to Eye Drop Formulation
Materials
Interaction of Native Cyclodextrins and Their Hydroxypropylated Derivatives with Carbamazepine in Aqueous Solution. Evaluation of Inclusion Complexes and Aggregates Formation
ACS Omega
Cyclodextrin–Amphiphilic Copolymer Supramolecular Assemblies for the Ocular Delivery of Natamycin
Nanomaterials
Development of celecoxib eye drop solution and microsuspension: a comparative investigation of binary and ternary cyclodextrin complexes
Carbohydrate Polymers
Self-association of cyclodextrins and cyclodextrin complexes in aqueous solutions
International Journal of Pharmaceutics
Interaction of native cyclodextrins and their hydroxypropylated derivatives with parabens in aqueous solutions. Part 2: evaluation of paraben/cyclodextrin complex aggregation
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Interaction of native cyclodextrins and their hydroxypropylated derivatives with parabens in aqueous solutions. Part 1: evaluation of inclusion complexes
Journal of Inclusion Phenomena and Macrocyclic Chemistry
2018
Novel excipients – Regulatory challenges and perspectives – The EU insight
International Journal of Pharmaceutics
Self-Assembly of α-Cyclodextrin and β-Cyclodextrin
Journal of Pharmaceutical Sciences
Pharmacokinetics and -dynamics of intramuscular and intranasal naloxone: An explorative study in healthy volunteers
European Journal of Clinical Pharmacology
Effect of β- and γ-cyclodextrins and their methylated derivatives on the degradation rate of benzylpenicillin
Journal of Inclusion Phenomena and Macrocyclic Chemistry
2-Hydroxypropyl-β-Cyclodextrin Aggregates: Identification and Development of Analytical Techniques
Materials
Disruption of α- and γ-cyclodextrin aggregates promoted by chaotropic agent (urea)
Journal of Drug Delivery Science and Technology
Self-assembled cyclodextrin-based nanoparticles for meropenem stabilization
Journal of Drug Delivery Science and Technology
Cyclodextrin solubilization of celecoxib: Solid and solution state characterization
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Topical drug delivery to the posterior segment of the eye
Journal of Drug Delivery Science and Technology
Topical drug delivery to the posterior segment of the eye
Journal of Drug Delivery Science and Technology
Self-assemble of α-cyclodextrin and β-cyclodextrin: Identification and development of analytical techniques
Journal of Pharmacological Sciences
Inclusion complexes of p-hydroxybenzoic acid esters and γ-cyclodextrin
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Solubility of Cyclodextrins and Drug/Cyclodextrin Complexes
Molecules
Cyclodextrins-based formulations: a non-invasive platform for targeted drug delivery
Basic and Clinical Pharmacology and Toxicology
Cyclodextrins: structure, physicochemical properties and pharmaceutical applications
International Journal of Pharmaceutics
2017
Editorial Special edition of International Journal of Pharmaceutics in honor of Professor Dominique Duchêne
International Journal of Pharmaceutics
Effects of cyclodextrins on the chemical stability of drugs
International Journal of Pharmaceutics
Soluble 1:1 complexes and insoluble 3:2 complexes – Understanding the phase-solubility diagram of hydrocortisone and γ-cyclodextrin
International Journal of Pharmaceutics
γ-Cyclodextrin
International Journal of Pharmaceutics
Cyclodextrin complexes of a globular protein and a lipophilic oligopeptide: the effect of structure and physicochemical properties
Pharmazie
Cyclodextrins and topical drug delivery to the anterior and posterior segments of the eye
International Journal of Pharmaceutics
Crystallographic and theoretical studies of inclusion complex of β-cyclodextrin with fentanyl
International Journal of Pharmaceutics
Evaluation of γ-cyclodextrin effect on permeation of lipophilic drugs: application of cellophane/fused octanol membrane
Pharmaceutical Development and Technology
Formulations and toxicologic in vivo studies of aqueous cyclosporin A eye drops with cyclodextrin nanoparticles
International Journal of Pharmaceutics
Drug solubilization by complexation
International Journal of Pharmaceutics
2016
Self-assembly of cyclodextrins and their complexes in aqueous solutions
Journal of Pharmacological Sciences
Effect of cyclodextrins on the degradation rate of benzylpenicillin
Pharmazie
Pharmacokinetics of cyclodextrins and drugs after oral and parenteral administration of drug/cyclodextrin complexes
Journal of Pharmacy and Pharmacology
Cyclodextrin-based telmisartan ophthalmic suspension: Formulation development for water-insoluble drugs
International Journal of Pharmaceutics
Topical Formulation Comprising Fatty Acid Extract from Cod Liver Oil: Development, Evaluation and Stability Studies
Marine Drugs
Fatty acids from marine lipids: biological activity, formulation and stability of fatty acids from cod-liver oil
Journal of Drug Delivery Science and Technology
Interaction of fentanyl with various cyclodextrins in aqueous solutions
Journal of Pharmacy and Pharmacology
Microspheres and nanotechnology for drug delivery, in Retinal Pharmacotherapy
The self-assemble of natural cyclodextrins in aqueous solutions: application of miniature permeation studies for critical aggregation concentration (cac) determinations
International Journal of Pharmaceutics
Free fatty acid suppositories are as effective as docusate sodium and sorbitol enemas in treating constipation in children
Acta Paediatrica, International Journal of Paediatrics
A Tribute to Dr. Marcus E. Brewster
Journal of Pharmaceutical Sciences
Cyclodextrin-poloxamer aggregates as nanocarriers in eye drop formulations: dexamethasone and amphotericin B
Drug Development and Industrial Pharmacy
Fatty acids from marine lipids
Journal of Drug Delivery Science and Technology
2015
Formation and stability assessment of self-assembled nanoparticles from large Mw chitosan and sulfobutylether-β-cyclodextrin
Journal of Drug Delivery Science and Technology
Development of eye drops containing antihypertensive drugs
Pharmaceutical Development and Technology
Development of a cyclodextrin-based aqueous cyclosporin A eye drop formulations
International Journal of Pharmaceutics
Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists
Formulation of drug-cyclodextrin complexes
Excipient pharmacokinetics and profiling
International Journal of Pharmaceutics
A new approach for quantitative determination of γ-cyclodextrin in aqueous solutions: application in aggregate determinations and solubility in hydrocortisone/γ-cyclodextrin inclusion complex
Journal of Pharmacy and Pharmaceutical Sciences
Microspheres and nanotechnology for drug delivery
Developments in Ophthalmology
Clinical trial: free fatty acid suppositories compared with enema as bowel preparation for flexible sigmoidoscopy.
Frontline Gastroenterology
Electroblowing and electrospinning of fibrous diclofenac sodium cyclodextrin complex-based reconstitution injection
Journal of Drug Delivery Science and Technology
Topical dexamethasone γ-cyclodextrin nanoparticle eye drops increase visual acuity and decrease macular thickness in diabetic macular oedema
Acta Ophthalmologica
2014
Kinetics of γ-cyclodextrin nanoparticle suspension eye drops in tear fluid
Acta Ophthalmologica
Sulfobutylether-β-cyclodextrin/chitosan nano- and microparticles and their physicochemical characteristics
International Journal of Pharmaceutics
γ-cyclodextrin nanoparticle eye drops with dorzolamide
Journal of Ocular Pharmacology and Therapeutics
Surface activity and self-aggregation ability of three cationic quaternized aminocalix[4]arenes
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Self-assembled cyclodextrin nanoparticles and drug delivery
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Drug Stability for Pharmaceutical Scientists
Physicochemical characterization and stability of microbeads containing cod-liver oil encircled with natural cyclodextrins
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Effect of γ-cyclodextrin on solubilization and complexation of irbesartan
International Journal of Pharmaceutics
Dorzolamide cyclodextrin nanoparticle suspension eye drops and trusopt in rabbit
Journal of Ocular Pharmacology and Therapeutics
2013
Encapsulation of drug molecules into Calix[n]arene Nanobaskets. Role of Aminocalix[n]arenes in biopharmaceutical field
Journal of Pharmaceutical Sciences
Triclosan-loaded with high encapsulation efficiency into PLA nanoparticles coated with β-cyclodextrin polymer
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrins
International Journal of Pharmaceutics
Cationic quaternized aminocalix[4]arenes: cytotoxicity, haemolytic and antibacterial activities
International Journal of Pharmaceutics
Physicochemical characterization and stability of microbeads containing cod-liver oil encircled with natural cyclodextrins
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Antifungal drug solubilizing activity and self-aggregation ability of cationic aminocalix[4]arene in comparison to SBEβCD: effect of addition of water-soluble polymer
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Dextran-based cyclodextrin polymers: Their solubilizing effect and self-association
Carbohydrate Polymers
Dexamethasone eye drops containing γ-cyclodextrin-based nanogels
International Journal of Pharmaceutics
A permeation method for detection of self-aggregation of doxorubicin in aqueous environment
International Journal of Pharmaceutics
Cyclodextrins
International Journal of Pharmaceutics
Drug Solubilization and Stabilization by Cyclodextrin Drug Carriers
Drug solubilization and stabilization of cyclodextrin drug carriers
For the special IJP issue "Poorly soluble drugs"
International Journal of Pharmaceutics
2012
Drug permeation through biomembranes: Cyclodextrins and the unstirred water layer
Pharmazie
The effect of parenterally administered cyclodextrins on the pharmacokinetics of coadministered drugs
Journal of Pharmaceutical Sciences
Cross-linked hydroxypropyl-β-cyclodextrin and γ-cyclodextrin nanogels for drug delivery
Carbohydrate Polymers
Complex Formation
Cyclodextrins as functional excipients: Methods to enhance complexation efficiency
Journal of Pharmaceutical Sciences
Clinical trial
Marine Drugs
Cyclodextrin-based nanogels for pharmaceutical and biomedical applications
International Journal of Pharmaceutics
Self-assembly of cyclodextrins: Formation of cyclodextrin polymer based nanoparticles
Journal of Drug Delivery Science and Technology
Topical drug delivery to the eye
Acta Ophthalmologica
2011
Self-assembly of cyclodextrin complexes: Aggregation of hydrocortisone/cyclodextrin complexes
International Journal of Pharmaceutics
Cyclodextrin-Enhanced Drug Delivery through Mucous Membranes
Drug loading in cyclodextrin polymers
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Topical dexamethasone-cyclodextrin nanoparticle eye drops improve visual acuity and reduce retinal thickness in diabetic macular edema
Investigative Ophthalmology and Visual Science
Drug/cyclodextrin: Beyond inclusion complexation
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Evaluation of sugammadex self-association
International Journal of Pharmaceutics
Self-assembly of cyclodextrin complexes: Effect of temperature, agitation and media composition on aggregation
International Journal of Pharmaceutics
Pharmaceutical applications of cyclodextrins: Effects on drug permeation through biological membranes
Journal of Pharmacy and Pharmacology
Self-assembly of cyclodextrin complexes: the effect of the guest molecule
International Journal of Pharmaceutics
Cyclodextrin enhanced drug delivery through mucus membranes
Cyclodextrin-Based Hydrogels
Preface: First European cyclodextrin conference
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Self-assembly of cyclodextrins: The effect of the guest molecule
International Journal of Pharmaceutics
Topical dexamethasone-cyclodextrin microparticle eye drops for diabetic macular edema
Investigative Ophthalmology and Visual Science
2010
Solubility and permeability of steroids in water in the presence of potassium halides
Die Pharmazie
Cyclodextrins as solubilizers: Formation of complex aggregates
Journal of Pharmaceutical Sciences
Cyclodextrin solubilization of carbonic anhydrase inhibitor drugs
European Journal of Pharmaceutics and Biopharmaceutics
Self-assembled cyclodextrin aggregates and nanoparticles
International Journal of Pharmaceutics
Studies of curcumin and curcuminoids. XXXVI. The stoichiometry and complexation constants of cyclodextrin complexes as determined by the phase-solubility method and UV-Vis titration
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Enalaprilat and enalapril maleate eyedrops lower intraocular pressure in rabbits
Acta Ophthalmologica
Effect of self-aggregation of γ-cyclodextrin on drug solubilization
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Aqueous solubility and true solutions
Pharmazie
γCD/HPγCD mixtures as solubilizer
Journal of Pharmacy and Pharmaceutical Sciences
Pharmaceutical applications of cyclodextrins: Basic science and product development
Journal of Pharmacy and Pharmacology
Effects of cogrinding with β-cyclodextrin on the solid state fentanyl
Journal of Pharmaceutical Sciences
γ-Cyclodextrin hydrogels and semi-interpenetrating networks for sustained delivery of dexamethasone
Carbohydrate Polymers
Evaluation of a cationic calix[4]arene: Solubilization and self-aggregation ability
International Journal of Pharmaceutics
Parenteral delivery of HPβCD: Effects on drug-HSA binding
AAPS PharmSciTech
2009
Crystal structure of fentanyl base
X-ray Structure Analysis Online
Fish skin as a model membrane: Structure and characteristics
Journal of Pharmacy and Pharmacology
Cyclodextrins and their use in pharmacy and cosmetology | Les cyclodextrines et leurs utilisations en pharmacie et cosmétologie
S.T.P. Pharma Pratiques
Drug targeting to the hair follicles: A cyclodextrin-based drug delivery
AAPS PharmSciTech
Diffusion characteristics of vitreous humour and saline solution follow the Stokes Einstein equation
Graefe's Archive for Clinical and Experimental Ophthalmology
CDs as solubilizers: Effects of excipients and competing drugs
International Journal of Pharmaceutics
Cyclodextrins as solubilizers: effects of excipients and competing drugs
International Journal of Pharmaceutics
2008
γCD/HPγCD: Synergistic solubilization
International Journal of Pharmaceutics
Topical drug delivery to the posterior segment of the eye
Pharmazie
Comparative interaction of 2-hydroxypropyl-β-cyclodextrin and sulfobutylether-β-cyclodextrin with itraconazole: Phase-solubility behavior and stabilization of supersaturated drug solutions
European Journal of Pharmaceutical Sciences
Physicochemical properties of water and its effect on drug delivery. A commentary
International Journal of Pharmaceutics
Carvedilol: Solubilization and cyclodextrin complexation: A technical note
AAPS PharmSciTech
2007
Cyclodextrins and their pharmaceutical applications
International Journal of Pharmaceutics
Development of octanol membranes for drug screening
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Antibacterial activity of methylated chitosan and chitooligomer derivatives
European Polymer Journal
Dexamethasone delivery to posterior segment of the eye
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Topical and systemic absorption in delivery of dexamethasone to the anterior and posterior segments of the eye
Acta Ophthalmologica Scandinavica
Studies on curcumin and curcuminoids. XXXI. Symmetric and asymmetric curcuminoids
International Journal of Pharmaceutics
Cyclodextrins and the liquid-liquid phase distribution of progesterone, estrone and prednicarbate
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Dexamethasone delivery to posterior segment of the eye
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrins and the liquid-liquid phase distributionof progesterone, estrone and prednicarbate.
Journal of Inclusion Phenomena and Macrocycle Chemistry
The complexation efficiency
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrins in ocular drug delivery: theoretinal basis with dexamethasone as a sample drug.
Journal of Drug Delivery Science and Technology
Cyclodextrin microparticles for drug delivery to the posterior segment of the eye
Journal of Pharmacy and Pharmacology
Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins
International Journal of Pharmaceutics
The Use of Solubilizing Excipients and Approaches to Generate Toxicology Vehicles for Contemporary Drug Pipelines.
Studies on Curcumin and Curcuminoids XXXI: Symmetric and Asymmetric curcuminoids: Their stability, activity and complexation with cyclodextrin.
International Journal of Pharmaceutics
Cyclodextrins as pharmaccutical solubilizers.
Advanced Drug Delivery Reviews
Effects of cyclodextrins on drug delivery through biological membranes
Journal of Pharmaceutical Sciences
Effects of various cyclodextrins on the stability of freeze-dried lactate dehydrogenase
Journal of Pharmaceutical Sciences
2006
Determination of aqueous solubility by heating and equilibration: A technical note
AAPS PharmSciTech
Assessment of mucoadhesion by a resonant mirror biosensor
International Journal of Pharmaceutics
Comparison of 0.7% dexamethasone-cyclodextrin with 0.1% dexamethasone sodium phosphate for postoperative inflammation
Graefe's Archive for Clinical and Experimental Ophthalmology
The pharmaceutical education in Iceland
Quality Assurance in Pharmacy Education
Influence of aqueous diffusion layer on passive drug diffusion from aqueous cyclodextrin solutions through biological membranes
Pharmazie
Development and evaluation of an artificial membrane for determination of drug availability
International Journal of Pharmaceutics
Ocular powder
Journal of Ocular Pharmacology and Therapeutics
Intranasal midazolam: A comparison of two delivery devices in human volunteers
Journal of Pharmacy and Pharmacology
Aquavitae. Áhrif vatns á lyfjaþróun
Investigation of soft long chain quaternary ammonium compounds as co-factors to enhance in vitro gene delivery
Pharmazie
Unexpected discrepancy between bioavailability and pharmacodynamic effect in the CNS when comparing two nasal sprays
Journal of Pharmacy and Pharmacology
The Stokes-Einstein equation and the physiological effects of vitreous surgery
Acta Ophthalmologica Scandinavica
2005
Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: effect of ionization and polymersCyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: effect of ionization and polymers
Journal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: formation of aggregates and higher-order complexes
International Journal of Pharmacy Practice
Investigation of drug-cyclodextrin complexes by a phase-distribution method
Chemical and Pharmaceutical Bulletin
Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarban
Journal of Inclusion Phenomena
Hydrolysis kinetics and QSAR investigation of soft antimicrobial agents
Journal of Pharmacy and Pharmacology
Cyclodextrin formulation of dorzolamide and its distribution in the eye after topical administration
Journal of Controlled Release
Cyclodextrins in drug delivery, Expert Opinion on Drug Delivery
Ashley Publications
Cyclodextrins in drug delivery
Expert Opinion on Drug Delivery
Design and Pharmaceutical Applications of Prodrugs
Evaluation of cyclodextrin solubilization of drugs
International Journal of Pharmaceutics
2004
The effects of water-soluble polymers on cyclodextrins and cyclodextrin solubilization of drugs
Journal of Drug Delivery Science and Technology
Self-Association of Cyclodextrins and Cyclodextrin Complexes
Journal of Pharmaceutical Sciences
Role of cyclodextrins in improving oral drug delivery
American Journal of Drug Delivery
Synthesis and Characterization of Chitosan N-betainates Having Various Degrees of Substitution
Macromolecules
Preparation of solid drug/cyclodextrin complexes of acidic and basic drugs
Pharmazie
Marine lipids as building blocks for soft quaternary ammonium compounds and their antibacterial activity
Pharmazie
Applications of chemically-modified cyclodextrins
Journal of Drug Delivery Science and Technology
2003
Sublingual delivery of 17β-estradiol from cyclodextrin containing tablets
Pharmazie
Soft antibacterial agents
Current Medicinal Chemistry
Soft antimicrobial agents
Journal of Medicinal Chemistry
Examination of
19
F-NMR as a tool for investigation of drug-cyelodextrin complexes
Drug Development and Industrial Pharmacy
The effects of cyclodextrins on topical delivery of hydrocortisone
S.T.P. Pharma Sciences
Investigation and physicochemical characterization of vinpocetine- sulfobutyl ether β-cyclodextrin binary and ternary complexes
Chemical and Pharmaceutical Bulletin
The effects of organic salts on the cyclodextrin solubilization of drugs
International Journal of Pharmaceutics
2002
Fish skin as a model membrane to study transmembrane drug delivery with cyclodextrins
Journal of Inclusion Phenomena
Cyclodextrins and the biopharmaceutics classification system of drugs
Journal of Inclusion Phenomena
The effects of cyclodextrins on hydrocortisone permeability through semi-permeable membranes
Journal of Inclusion Phenomena
Cyclodextrins and drug permeability through semi-permeable cellophane membranes
International Journal of Pharmaceutics
Mucoadhesive sustained drug delivery system based on cationic polymer and anionic cyclodextrin/triclosan complex
Journal of Inclusion Phenomena
Cyclodextrins in eye drop formulations
Journal of Inclusion Phenomena
Cycloserine fatty acid derivatives as prodrugs
Chemical and Pharmaceutical Bulletin
Self association and cyclodextrin solubilization of NSAIDs
Journal of Inclusion Phenomena
Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation
International Journal of Pharmaceutics
Self-association and cyclodextrin solubilization of drugs
Journal of Pharmaceutical Sciences
Cyclodextrins in eye drop formulations
Acta Ophthalmologica Scandinavica
Cyclodextrins and drug permeability through semi-permeable cellophane membranes
International Journal of Pharmaceutics
The use of chemically modified cyclodextrins in the development of formulations for chemical delivery systems
Pharmazie
Preface
Journal of Inclusion Phenomena
Buccal absorption of ergotamine tartrate using the bioadhesive tablet system in guinea-pigs
International Journal of Pharmaceutics
2001
Cyclodextrin solubilization of benzodiazepines
International Journal of Pharmaceutics
Cyclodextrins in topical drug formulations
International Journal of Pharmaceutics
Sustained drug delivery system based on a cationic polymer and an anionic drug/cyclodextrin complex
Pharmazie
Intranasal administration of midazolam in a cyclodextrin based formulation
Pharmazie
2000
Methazolamide 1% in cyclodextrin solution lowers IOP in human ocular hypertension
Investigative Ophthalmology and Visual Science
Marine lipids for prodrugs, soft compounds and other pharmaceutical applications
Pharmazie
Dermal delivery of ETH-615, a zwitterionic drug
Drug Development and Industrial Pharmacy
Lipophilic metronidazole derivatives and their absorption through hairless mouse skin
Pharmazie
1999
Synthesis of cyclic glycerol ether cyclodextrin derivatives and investigation of their binding properties with drugs
Journal of Inclusion Phenomena
Influence of cyclodextrins on the stability of the peptide salmon calcitonin in aqueous solution
International Journal of Pharmaceutics
Diacyl glyceryl ester prodrugs for slow release in the skin
Pharmazie
Drug-cyclodextrin complexation in the presence of water-soluble polymers
ACS Symposium Series
Effect of cyclodextrins and polymers on triclosan availability and substantivity in toothpastes in vivo
Journal of Pharmaceutical Sciences
Soft drugs based on hydrocortisone: The inactive metabolite approach and its application to steroidal antiinflammatory agents
Pharmaceutical Research
Cyclodextrins as permeation enhancers
Journal of Controlled Release
Methods to enhance the complexation efficiency of cyclodextrins
S.T.P. Pharma Sciences
Pharmaceutical applications of β-cyclodextrin
Pharmaceutical Technology
Pharmaceutical applications of β-Cyclodextrin
Pharmaceutical Technology Europe
1998
Cyclodextrins: new drug delivery systems in dermatology
International Journal of Dermatology
Stabilisation of ionic drugs through complexation with non-ionic and ionic cyclodextrins
International Journal of Pharmaceutics
Cyclodextrins as co-enhancers in dermal and transdermal drug delivery
Pharmazie
Co-administration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage forms
Pharmaceutical Research
Aqueous hydrocortisone mouthwash solution: Clinical evaluation
Acta Odontologica Scandinavica
Effect of cod-liver oil extract on the buccal permeation of ergotamine tartrate
Drug Development and Industrial Pharmacy
Effect of the cod-liver oil extract on the buccal permeation of ionized and nonionized forms of ergotamine using the keratinized epithelial-free membrane of hamster cheek pouch mucosa
International Journal of Pharmaceutics
Increasing the cyclodextrin complexation of drugs and drug biovailability through addition of water-soluble polymers
Pharmazie
Effect of cod-liver oil extract on the buccal permeation of ergotamine tartrate
Proceedings of the Controlled Release Society
Cyclodextrin solubilization of ETH-615, a zwitterionic drug
Drug Development and Industrial Pharmacy
The effect of water-soluble polymers on the aqueous solubility and complexing abilities of β-cyclodextrin
International Journal of Pharmaceutics
Fatty acid extract from cod-liver oil: Activity against herpes simplex virus and enhancement of transdermal delivery of acyclovir in-vitro
Pharmacy and Pharmacology Communications
1997
Cyclodextrin solubilization of water-soluble drugs: Calcipotriol and EB-1089
Pharmazie
Effect of various marine lipids on transdermal drug delivery - in vitro evaluation
Bollettino Chimico Farmaceutico
Formulation and testing of methazolamide cyclodextrin eye drop solutions
Journal of Controlled Release
Unsaturated glycerol monoethers as novel skin penetration enhancers
Pharmazie
Effect of cyclodextrins on topical drug delivery to the eye
Drug Development and Industrial Pharmacy
1996
Dexamethasone-cyclodextrin-polymer co-complexes in aqueous eye drops
Investigative Ophthalmology and Visual Science
Formulation and clinical evaluation of a hydrocortisone solution for the treatment of oral disease
International Journal of Pharmaceutics
Design and in vivo testing of 17β-estradiol-HPβCD sublingual tablets
Pharmazie
Pharmaceutical Applications of Cyclodextrins. 1. Drug Solubilization and Stabilization
Journal of Pharmaceutical Sciences
The effect of water-soluble polymers on aqueous solubility of drugs
International Journal of Pharmaceutics
Potentiation of anticancer effects of microencapsulated carboplatin by hydroxypropyl α-cyclodextrin
Journal of Controlled Release
Effects of cyclodextrins and polymers on transdermal drug delivery
Proceedings of the Controlled Release Society
The influence of water-soluble polymers and pH on hydroxypropyl-β-cyclodextrin complexation of drugs
Drug Development and Industrial Pharmacy
Topically effective acetazolamide eye-drop solution in man
Pharmaceutical Sciences
Effects of cyclodextrins and polymers on topical drug delivery to the eye - Evaluations in humans
Proceedings of the Controlled Release Society
Complexation of Drug Compounds with Ionic and Non-Ionic Cyclodextrins
1995
Fatty acids from cod-liver oil as skin penetration enhancers
Pharmazie
Formulation development for a zidovudine chemical delivery system 2. Towards oral and non-parenteral dosage forms
International Journal of Pharmaceutics
Preparation, characterization, and anesthetic properties of 2- hydroxypropyl-β-cyclodextrin complexes of pregnanolone and pregnenolone in rat and mouse
Journal of Pharmaceutical Sciences
Formulation development for a zidovudine chemical delivery system 1. Parenteral dosage forms
International Journal of Pharmaceutics
Improved acitretin delivery through hairless mouse skin by cyclodextrin complexation
International Journal of Pharmaceutics
The effect of polyvinylpyrrolidone on cyclodextrin complexation of hydrocortisone and its diffusion through hairless mouse skin
International Journal of Pharmaceutics
1994
The effect of polyvinylpyrrolidone and hydroxypropyl methylcellulose on HPβCD complexation of hydrocortisone and its permeability through hairless mouse skin
European Journal of Pharmaceutical Sciences
The effect of water-soluble polymers on drug-cyclodextrin complexation
International Journal of Pharmaceutics
Effect of cyclodextrins on the degradation of cortisone acetate, oestradiol benzoate and prednicarbate in aqueous solution
S.T.P. Pharma Sciences
Topically effective ocular hypotensive acetazolamide and ethoxyzolamide formulations in rabbits
Journal of Pharmacy and Pharmacology
2-hydroxypropyl-β-cyclodextrin in topical carbonic anhydrase inhibitor formulations
European Journal of Pharmaceutical Sciences
The pharmacokinetics and transdermal delivery of loteprednol etabonate and related soft steroids
Advanced Drug Delivery Reviews
The influence of cyclodextrins on the stability of cephalotin and aztreonam in aqueous solutions
Pharmazie
The influence of 2-hydroxypropyl-β-cyclodextrin on diffusion rates and transdermal delivery of hydrocortisone
Drug Development and Industrial Pharmacy
Pharmacy in iceland
Annals of Pharmacotherapy
The effect of hydroxypropyl methylcellulose on the release of dexamethasone from aqueous 2-hydroxypropyl-β-cyclodextrin formulations
International Journal of Pharmaceutics
1993
Topical delivery of acetazolamide for psoriasis
Acta Dermato-Venereologica
Cyclodextrin complexation of NSAIDs: Physicochemical characteristics
European Journal of Pharmaceutical Sciences
The effect of cyclodextrins on the solubility and stability of medroxyprogesterone acetate and megestrol acetate in aqueous solution
International Journal of Pharmaceutics
Nýjar aðferðir til að hafa áhrif á frásog og dreifingu lyfja
Læknablaðið
1992
Degradation of tauromustine (TCNU) in aqueous solutions
Acta Pharmaceutica Nordica
Improved delivery through biological membranes. XLV. Synthesis, physical-chemical evaluation, and brain uptake studies of 2-chloroethyl nitrosourea delivery systems
Pharmaceutical Research
Interactions between preservatives and 2-hydroxypropyl-β-cyclodextrin
Drug Development and Industrial Pharmacy
Stabilizing Effect of Tris(hydroxymethyl)aminomethane on N-Nitrosoureas in Aqueous Solutions
Journal of Pharmaceutical Sciences
Estramustine: Hydrolysis, solubilization, and stabilization in aqueous solutions
International Journal of Pharmaceutics
Preparation and physical evaluation of microcapsules of hydrophilic drug-cyclodextrin complexes
Journal of Microencapsulation
Metabolism, Distribution, and Transdermal Permeation of a Soft Corticosteroid, Loteprednol Etabonate
Pharmaceutical Research
The stability of aspartame in aqueous solutions
Acta Pharmaceutica Nordica
Effect of various cyclodextrins on solution stability and dissolution rate of doxorubicin hydrochloride
International Journal of Pharmaceutics
1991
Solubilization and stabilization of a benzylpenicillin chemical delivery system by 2-hydroxypropyl-β-cyclodextrin
Pharmaceutical Research
Stabilization of aspartame by cyclodextrins
International Journal of Pharmaceutics
Solubilization and stabilization of drugs through cyclodextrin complexation
Acta Pharmaceutica Nordica
2-Hydroxypropyl-β-cyclodextrin: Properties and usage in pharmaceutical formulations
PZ Wissenschaft
Cyclodextrin-accelerated degradation of β-lactam antibiotics in aqueous solutions
International Journal of Pharmaceutics
The effects of cyclodextrins on transdermal delivery of drugs
European Journal of Pharmaceutics and Biopharmaceutics
1990
Novel central nervous system targeted semisynthetic penicillins
Drug Design and Delivery
Degradation of lomustine (CCNU) in aqueous solutions
International Journal of Pharmaceutics
Comparative study on inclusion complexation of acetylsalicylic acid, cholecalciferol and melphalan with β- and γ-cyclodextrin and some of their derivatives
Acta Pharmaceutica Nordica
The effect of 2-hydroxypropyl-β-cyclodextrin on the simultaneous dissolution and degradation of chlorambucil
International Journal of Pharmaceutics
The effect of phosphine oxides on transdermal delivery
Acta Pharmaceutica Nordica
1989
The effects of 2-hydroxypropyl-β-cyclodextrin on the solubility and stability of chlorambucil and melphalan in aqueous solution
International Journal of Pharmaceutics
Effects of 2-hydroxypropyl-β-cyclodextrin on the aqueous solubility of drugs and transdermal delivery of 17β-estradiol
Acta Pharmaceutica Nordica
Effect of oleic acid on diffusion of drugs through hairless mouse skin
Acta Pharmaceutica Nordica
Effect of choline esters and oleic acid on the penetration of acyclovir, estradiol, hydrocortisone, nitroglycerin, retinoic acid and trifluorothymidine across hairles mouse skin in vitro
Acta Pharmaceutica Nordica
1988
Improved delivery through biological membranes XXXI: Solubilization and stabilization of an estradiol chemical delivery system by modified β-cyclodextrins
Journal of Pharmaceutical Sciences
1987
Trifluorothymidine: potential non-invasive diagnosis of herpes simplex infection using 19F nuclear magnetic resonance in a murine hepatitis model
Journal of Virological Methods
The effect of vehicle additives on the transdermal delivery of nitroglycerin
Pharmaceutical Research
1985
The effect of ionization on partition coefficients and topical delivery
Acta Pharmaceutica Suecica
1984
Soft drugs VI. The application of the inactive metabolite approach for design of soft β-blockers
Pharmaceutical Research
Synthesis and evaluation of novel lidocaine sulfur analogs
International Journal of Pharmaceutics
1981
Improved delivery through biological membranes VIII: Design, synthesis, and in vivo testing of true prodrugs of aspirin
Journal of Pharmaceutical Sciences
Improved delivery through biological membranes IX: Kinetics and mechanism of hydrolysis of methylsulfinylmethyl 2-acetoxybenzoate and related aspirin prodrugs
Journal of Pharmaceutical Sciences
Improved delivery through biological membranes X: Percutaneous absorption and metabolism of methylsulfinylmethyl 2-acetoxybenzoate and related aspirin prodrugs
Journal of Pharmaceutical Sciences
Keywords for Specialisation:
Nanomedicine
Cyclodextrin
Solubility
Bioavailability
Mucosa
Ophtalmic drug delivery
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