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A symposium was held in Reykjavík in mid-September, organised by the University of Iceland (UI), the National University Hospital of Iceland (Landspítali), and the University of Innsbruck. Its purpose was to create a platform for interdisciplinary dialogue on medication safety, research, and clinical innovation to promote better quality and increased patient safety in relation to delirium.

In recent years, the University of Iceland, in collaboration with Landspítali, has engaged in robust research cooperation with the University of Innsbruck in Austria, particularly with Professor Anita Weidmann. The research group, led by Freyja Jónsdóttir, Associate Professor at the Faculty of Pharmaceutical Sciences, on behalf of the University of Iceland, has primarily focused on medications that may potentially be a causative factor in developing delirium among various patient groups. The objective is to lay the groundwork for international clinical guidelines.

At-risk groups

Delirium is a syndrome characterised by a disturbance in attention, consciousness, cognitive ability, and sensory perception. Delirium has a sudden onset and a fluctuating course. Delirium is a common, serious, and complex problem associated with poor prognosis for those who contract it. By responding quickly and correctly, delirium can be prevented, and recovery outcomes can be improved. Certain patient groups are at particular risk of developing delirium, such as patients with dementia, the elderly, and patients undergoing surgery.

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Freyja Jónsdóttir, Associate Professor at the UI Faculty of Pharmaceutical Sciences, leads the COMeD research group, and she was one of the speakers at the symposium.

The COMeD research group

The COnsensus Guideline on Medication at Risk of Inducing a Delirium (COMeD) research group is working to shed light on medication-related risk factors in connection with the development, treatment, and prevention of delirium in different patient groups (children, adults, those undergoing surgery, as well as those with dementia or cancer). As previously stated, the goal is to develop comprehensive, international clinical guidelines while also increasing the understanding of the role of medications in developing delirium in these patient groups. Several university students at both universities have had the opportunity to conduct research as part of the COMeD research group.

Below are links to two recent articles from the research group:

Medication Causes and Treatment of Delirium in Patients With and Without Dementia

Medication-induced causes of delirium in patients with and without dementia: a systematic review of published neurology guidelines

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