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Vilmundur G Guðnason - Professor Emeritus

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Heilbrigðisvísindasvið

Vilmundur G Guðnason

Professor Emeritus

Location
Utan H.Í.
Phone
5351800
Email
vgg [at] hi.is

Unit
Faculty of Medicine
Website
https://scholar.google.com/citations?user=eDkARCwAAAAJ;

Published works

2024

Vascular Age Assessed From an Uncalibrated, Noninvasive Pressure Waveform by Using a Deep Learning Approach: The AI-VascularAge ModelHypertension
Identification of Distinct Brain MRI Phenotypes and Their Association With Long-Term Dementia Risk in Community-Dwelling Older AdultsNeurology

2023

Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH.Diabetologia
White matter hyperintensity shape is associated with long-term dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association
Serum DHEA and Testosterone Levels Associate Inversely with Coronary Artery Calcification in Elderly Men.The Journal of clinical endocrinology and metabolism
CKD-EPI and EKFC GFR Estimating Equations: Performance and Other Considerations for Selecting Equations for Implementation in AdultsJournal of the American Society of Nephrology
Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization [version 1; peer review: awaiting peer review]
Diminishing benefits of urban living for children and adolescents' growth and development.Nature
Identification of biomarkers for glycaemic deterioration in type 2 diabetes.Nature communications
Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study.European heart journal
Exposure factors associated with dementia among older adults in Iceland: the AGES-Reykjavik studyGeroScience
Fast and robust femur segmentation from computed tomography images for patient-specific hip fracture risk screeningComputer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization
Comparative study of machine learning methods for modeling associations between risk factors and future dementia casesGeroScience
Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity.Stroke
Associations of plasma NfL, GFAP, and t-tau with cerebral small vessel disease and incident dementia: longitudinal data of the AGES-Reykjavik StudyGeroScience

2022

[The relationship between lack of educational attainment, cardiovascular risk factors, atherosclerosis and coronary artery disease].Laeknabladid
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.American journal of human genetics
Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.Molecular psychiatry
A population-based meta-analysis of circulating GFAP for cognition and dementia risk.Annals of clinical and translational neurology
The relationship between interstitial lung abnormalities, mortality, and multimorbidity: a cohort study.Thorax
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.Communications biology
A proteogenomic signature of age-related macular degeneration in blood.Nature communications
Social network and the risk for developing mild cognitive impairment and dementia among older adults.Aging clinical and experimental research
Cerebrovascular Risk-Factors of Prevalent and Incident Brain Infarcts in the General Population: The AGES-Reykjavik StudyStroke
Association of change in cardiovascular risk factors with incident dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association
Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses.Circulation
Late-life depression, allostatic load, and risk of dementia: The AGES-Reykjavik study.Psychoneuroendocrinology
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.Genome biology
Cognition and brain health among older adults in Iceland: the AGES-Reykjavik studyGeroScience
Metabolic and proteomic signatures of type 2 diabetes subtypes in an Arab populationNature Communications
Depression and Dementia: The Role of Cortisol and Vascular Brain Lesions. AGES-Reykjavik Study.Journal of Alzheimer's disease : JAD
Stroke genetics informs drug discovery and risk prediction across ancestries
The Proteomic Profile of Interstitial Lung Abnormalities.American journal of respiratory and critical care medicine
Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations.Journal of thrombosis and haemostasis : JTH
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.Nature genetics
Adjusting conventional FRAX estimates of fracture probability according to the number of prior fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Stroke genetics informs drug discovery and risk prediction across ancestries.Nature
Associations of Pulmonary Function with MRI Brain Volumes: A Coordinated Multi-Study Analysis.Journal of Alzheimer's disease : JAD
A meta-analysis of genome-wide association studies identifies new genetic loci associated with all-cause and vascular dementia
Mid- and later-life risk factors for predicting neuropathological brain changes associated with Alzheimer's and vascular dementia: The Honolulu Asia Aging Study and the Age, Gene/Environment Susceptibility-Reykjavik Study.Alzheimer's & dementia : the journal of the Alzheimer's Association
Heart failure risk is accurately predicted by certain serum proteins
A saturated map of common genetic variants associated with human height.Nature
Growth Rate in Childhood and Adolescence and the Risk of Breast and Prostate Cancer: A Population-Based Study.American journal of epidemiology
Creativity, leisure activities, social engagement and cognitive impairment: the AGES-Reykjavík study.Aging clinical and experimental research
A genome-wide association study of serum proteins reveals shared loci with common diseases.Nature communications
Coding and regulatory variants are associated with serum protein levels and disease.Nature communications
Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 individuals Across 13 Cohorts.Diabetes care
Interstitial lung abnormalities are associated with decreased mean telomere length.The European respiratory journal
Carotid plaque is strongly associated with coronary artery calcium and predicts incident coronary heart disease in a population-based cohort.Atherosclerosis
APOE ε4 and late-life cognition: mediation by structural brain imaging markers.European journal of epidemiology
Circulating serum microRNAs including senescent miR-31-5p are associated with incident fragility fractures in older postmenopausal women with type 2 diabetes mellitus.Bone
Saturated and Unsaturated Bone Marrow Lipids Have Distinct Effects on Bone Density and Fracture Risk in Older Adults.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
A joint ventricle and WMH segmentation from MRI for evaluation of healthy and pathological changes in the aging brainPLOS ONE
Depressive symptom profiles predict dementia onset and brain pathology in older persons. The AGES-Reykjavik studyNeurobiology of Aging
Genome-wide analysis in over 1 million individuals reveals over 2,000 independent genetic signals for blood pressure
New insights into the genetic etiology of Alzheimer's disease and related dementias.Nature genetics
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.Nature genetics
Update of the fracture risk prediction tool FRAX: a systematic review of potential cohorts and analysis plan.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss.American journal of human genetics
Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate. Brain : a journal of neurology

2021

Dementia risk in the general population: large-scale external validation of prediction models in the AGES-Reykjavik study.European journal of epidemiology
New Creatinine- and Cystatin C-Based Equations to Estimate GFR without Race.The New England journal of medicine
Identification of Functional Genetic Determinants of Cardiac Troponin T and I in a Multiethnic Population and Causal Associations With Atrial Fibrillation.Circulation. Genomic and precision medicine
Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci.Human molecular genetics
The trans-ancestral genomic architecture of glycemic traits.Nature genetics
Serum 25-Hydroxy-Vitamin D Status and Incident Hip Fractures in Elderly Adults: Looking Beyond Bone Mineral Density.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Soft tissue radiodensity parameters mediate the relationship between self-reported physical activity and lower extremity function in AGES-Reykjavík participants.Scientific reports
Association of low-frequency and rare coding variants with information processing speed.Translational psychiatry
Omega-3 and omega-6 polyunsaturated fatty acid biomarkers and sleep: a pooled analysis of cohort studies On behalf of the Fatty Acids and Outcomes Research Consortium (FORCE). The American journal of clinical nutrition
The power of genetic diversity in genome-wide association studies of lipids.Nature
Associations of Monocyte Count and Other Immune Cell Types with Interstitial Lung Abnormalities.American journal of respiratory and critical care medicine
Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia riskNature Aging
A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction.The Journal of clinical endocrinology and metabolism
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.Nature communications
Body weight changes and longitudinal associations with cognitive decline among community-dwelling older adults.Alzheimer's & dementia (Amsterdam, Netherlands)
Diffuse idiopathic skeletal hyperostosis in elderly Icelanders and its association with the metabolic syndrome: the AGES-Reykjavik Study.Scandinavian journal of rheumatology
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight.eLife
Wave Reflection at the Origin of a First-Generation Branch Artery and Target Organ Protection: The AGES-Reykjavik Study.Hypertension (Dallas, Tex. : 1979)
Progression of traction bronchiectasis/bronchiolectasis in interstitial lung abnormalities is associated with increased all-cause mortality: Age Gene/Environment Susceptibility-Reykjavik Study.European journal of radiology open
Computed tomography-based skeletal muscle and adipose tissue attenuation: Variations by age, sex, and muscle.Experimental gerontology
Accelerated decline in quadriceps area and Timed Up and Go test performance are associated with hip fracture risk in older adults with impaired kidney function.Experimental gerontology
Genetic insights into biological mechanisms governing human ovarian ageing.Nature
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.Lancet (London, England)
Copeptin is associated with mortality in elderly people.European journal of clinical investigation
Serum FSH Is Associated With BMD, Bone Marrow Adiposity, and Body Composition in the AGES-Reykjavik Study of Older Adults.The Journal of clinical endocrinology and metabolism
Associations of ω-3 Fatty Acids With Interstitial Lung Disease and Lung Imaging Abnormalities Among Adults.American journal of epidemiology
Multiethnic Genome-Wide Association Study of Subclinical Atherosclerosis in Individuals With Type 2 Diabetes.Circulation. Genomic and precision medicine
Dietary patterns in adolescence and risk of colorectal cancer: a population-based study.Cancer causes & control : CCC
FSH Level and Changes in Bone Mass and Body Composition in Older Women and Men.The Journal of clinical endocrinology and metabolism
Sex-specific 25-hydroxyvitamin D threshold concentrations for functional outcomes in older adults: PRoject on Optimal VItamin D in Older adults (PROVIDO).The American journal of clinical nutrition
A proteome-wide genetic investigation identifies several SARS-CoV-2-exploited host targets of clinical relevance.eLife
The effect on subsequent fracture risk of age, sex, and prior fracture site by recency of prior fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction.Human molecular genetics
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure.Molecular psychiatry
Exploratory assessment of pineal gland volume, composition, and urinary 6-sulfatoxymelatonin levels on prostate cancer risk.The Prostate
Contributions of Cerebral Blood Flow to Associations Between Blood Pressure Levels and Cognition: The Age, Gene/Environment Susceptibility-Reykjavik Study.Hypertension (Dallas, Tex. : 1979)
Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies.Nature communications
[Prevalence and incidence of type 2 diabetes in Iceland 2005-2018].Laeknabladid
Finite element derived femoral strength is a better predictor of hip fracture risk than aBMD in the AGES Reykjavik study cohort.Bone
Social Participation and the Risk for Developing Mild Cognitive Impairment and Dementia Among Older AdultsInnovation in aging

2020

Type 2 Diabetes, Change in Depressive Symptoms Over Time, and Cerebral Small Vessel Disease: Longitudinal Data of the AGES-Reykjavik Study.Diabetes care
GFR in Healthy Aging: an Individual Participant Data Meta-Analysis of Iohexol Clearance in European Population-Based CohortsJournal of the American Society of Nephrology
Serum levels of ACE2 are higher in patients with obesity and diabetesObesity Science and Practice
The associations of interstitial lung abnormalities with cancer diagnoses and mortality.The European respiratory journal
Serum levels of ACE2 are higher in patients with obesity and diabetes.Obesity science & practice
Correction to: Characteristics of incidence hip fracture cases in older adults participating in the longitudinal AGES-Reykjavik study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits.HGG advances
Assessing cardiovascular risks from a mid-thigh CT image: a tree-based machine learning approach using radiodensitometric distributions.Scientific reports
A pooled-analysis of age and sex based coronary artery calcium scores percentiles.Journal of cardiovascular computed tomography
Childhood overweight and obesity and the risk of depression across the lifespan.BMC pediatrics
National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries.International journal of epidemiology
Traction Bronchiectasis/Bronchiolectasis is Associated with Interstitial Lung Abnormality Mortality.European journal of radiology
Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes.Diabetes
Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose.PloS one
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.Molecular psychiatry
Lifestyle and 25-hydroxy-vitamin D among community-dwelling old adults with dementia, mild cognitive impairment, or normal cognitive function.Aging clinical and experimental research
The genetic architecture of the human cerebral cortex.Science (New York, N.Y.)
Quantitative 3D imaging parameters improve prediction of hip osteoarthritis outcome.Scientific reports
Improved brain perfusion after electrical cardioversion of atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.American journal of respiratory and critical care medicine
Cigarette Smoking Is Associated With Lower Quadriceps Cross-sectional Area and Attenuation in Older Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Molecular screening of familial hypercholesterolemia in Icelanders.Scandinavian journal of clinical and laboratory investigation
Adjusting conventional FRAX estimates of fracture probability according to the recency of sentinel fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium.Neurology
Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies.PLoS medicine
Antihypertensive medication uses and serum ACE2 levels
Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities.Stroke
GFR in Healthy Aging: an Individual Participant Data Meta-Analysis of Iohexol Clearance in European Population-Based Cohorts.Journal of the American Society of Nephrology : JASN
Repositioning of the global epicentre of non-optimal cholesterol.Nature
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.Nature communications
Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis.JAMA cardiology
The genetics of circulating BDNF: towards understanding the role of BDNF in brain structure and function in middle and old ages.Brain communications
Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.PloS one
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants.Lancet (London, England)
The use of 2-, 5-, and 10-year probabilities to characterize fracture risk after a recent sentinel fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
It's in Our Blood: A Glimpse of Personalized Medicine.Trends in molecular medicine
Association of common genetic variants with brain microbleeds: A genome-wide association study.Neurology
rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis.Journal of hepatology
Characteristics of incidence hip fracture cases in older adults participating in the longitudinal AGES-Reykjavik study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Bone density and strength from thoracic and lumbar CT scans both predict incident vertebral fractures independently of fracture location.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Hiatus hernia and interstitial lung abnormalities.The European respiratory journal
A New Panel-Estimated GFR, Including β₂-Microglobulin and β-Trace Protein and Not Including Race, Developed in a Diverse Population.American journal of kidney diseases : the official journal of the National Kidney Foundation
Cerebral small vessel disease genomics and its implications across the lifespan.Nature communications
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.Nature genetics
Omega-3 Fatty Acid Biomarkers and Sleep: Pooled Analysis of Prospective Studies in the Fatty Acids and Outcome Research Consortium (FORCE)Current developments in nutrition

2019

Comparability of Plasma Iohexol Clearance Across Population-Based Cohorts.American journal of kidney diseases : the official journal of the National Kidney Foundation
Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry.The pharmacogenomics journal
Greater Bone Marrow Adiposity Predicts Bone Loss in Older Women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Overlap of Genetic Risk between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis.American journal of respiratory and critical care medicine
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.Nature genetics
Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection.Journal of the American College of Cardiology
Serum lipids in adults with late age-related macular degeneration: a case-control study.Lipids in health and disease
Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European Cohorts.Nutrients
Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.Circulation
Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study.Neurology
Disentangling the genetics of lean mass.The American journal of clinical nutrition
Distribution of cerebral microbleeds in the East and West: Individual participant meta-analysis.Neurology
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.European journal of human genetics : EJHG
Hand and knee osteoarthritis are associated with reduced diameters in retinal vessels: the AGES-Reykjavik study.Rheumatology international
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.Nature communications
Structural covariability hubs in old age.NeuroImage
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.Neurology
Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies.European heart journal
Prevalence and prognosis of ischaemic and non-ischaemic myocardial fibrosis in older adults.European heart journal
Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes.Hepatology communications
Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes: a pooled analysis of prospective cohort studies.The American journal of clinical nutrition
Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.Circulation
Dynamic sitting: Measurement and associations with metabolic health.Journal of sports sciences
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.Nature genetics
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.Nature genetics
Pre-diagnostic 25-hydroxyvitamin D levels and survival in cancer patients.Cancer causes & control : CCC
Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study.JAMA cardiology
Cardiovascular Risk Factors Associated With Venous Thromboembolism.JAMA cardiology
Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association.American journal of respiratory and critical care medicine
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals.Journal of the American College of Cardiology
[Novel Innovation: Can Artificial Intelligence make Rehabilitation more Efficient?]Laeknabladid
Body fat distribution on computed tomography imaging and prostate cancer risk and mortality in the AGES-Reykjavik study.Cancer
Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.Nature genetics
A catalog of genetic loci associated with kidney function from analyses of a million individuals.Nature genetics
Association Between Unrecognized Myocardial Infarction and Cerebral Infarction on Magnetic Resonance Imaging.JAMA neurology
Rising rural body-mass index is the main driver of the global obesity epidemic in adults.Nature
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.Nature communications
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.American journal of epidemiology
World Health Organization cardiovascular disease risk charts: revised models to estimate risk in 21 global regions.The Lancet. Global health
Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans.PloS one
Hyperuricemia is associated with intermittent hand joint pain in a cross sectional study of elderly females: The AGES-Reykjavik Study.PloS one
Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.Nature genetics
A meta-analysis of genome-wide association studies identifies multiple longevity genes.Nature communications
Imaging Patterns Are Associated with Interstitial Lung Abnormality Progression and Mortality.American journal of respiratory and critical care medicine
SegAE: Unsupervised white matter lesion segmentation from brain MRIs using a CNN autoencoder.NeuroImage. Clinical
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.Nature communications
Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies.The Lancet. Neurology
Associations of autozygosity with a broad range of human phenotypes.Nature communications
HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype.Nature genetics
Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment.Scientific reports
Genetic architecture of subcortical brain structures in 38,851 individuals.Nature genetics
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.Nature genetics
Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group.American journal of hypertension
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.Nature communications
Type 2 diabetes and obesity in midlife and breast cancer risk in the Reykjavik cohort.Cancer causes & control : CCC
Body size at birth and age-related macular degeneration in old age.Acta ophthalmologica
Predicting health and life span with the deep plasma proteome.Nature medicine
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.Communications biology
The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE).PloS one
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.Human molecular genetics
Validation of a Metabolite Panel for a More Accurate Estimation of Glomerular Filtration Rate Using Quantitative LC-MS/MS.Clinical chemistry

2018

Sex differences in the spatial distribution of bone in relation to incident hip fracture: Findings from the AGES-Reykjavik study.Bone
Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval.Circulation. Genomic and precision medicine
Advanced quantitative methods in correlating sarcopenic muscle degeneration with lower extremity function biometrics and comorbidities.PloS one
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.Nature genetics
Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.Human molecular genetics
Interstitial lung abnormalities and physical function.ERJ open research
Reversal of Aging-Induced Increases in Aortic Stiffness by Targeting Cytoskeletal Protein-Protein Interfaces.Journal of the American Heart Association
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.Genome biology
The risk of developing a mismatch repair deficient colorectal cancer after undergoing cholecystectomy.Scandinavian journal of gastroenterology
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.American journal of human genetics
Clinical significance of cerebral microbleeds on MRI: A comprehensive meta-analysis of risk of intracerebral hemorrhage, ischemic stroke, mortality, and dementia in cohort studies (v1).International journal of stroke : official journal of the International Stroke Society
Population distribution of traditional and the emerging cardiovascular risk factors carotid plaque and IMT: the REFINE-Reykjavik study with comparison with the Tromsø study.BMJ open
Dietary habits in adolescence and midlife and risk of breast cancer in older women.PloS one
Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies.PLoS medicine
Effects of vitamin D supplementation on markers for cardiovascular disease and type 2 diabetes: an individual participant data meta-analysis of randomized controlled trials.The American journal of clinical nutrition
The AGES-Reykjavik Study suggests that change in kidney measures is associated with subclinical brain pathology in older community-dwelling persons.Kidney international
Characteristics of recurrent fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Interstitial lung abnormalities and self-reported health and functional status.Thorax
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.PloS one
Multi-ethnic genome-wide association study for atrial fibrillation.Nature genetics
Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function.The British journal of nutrition
Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study.BMJ (Clinical research ed.)
Chronic Kidney Disease Is Associated With Greater Bone Marrow Adiposity.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Co-regulatory networks of human serum proteins link genetics to disease.Science (New York, N.Y.)
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.Nature communications
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.Nature communications
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.Nature genetics
Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.Alzheimer's & dementia (Amsterdam, Netherlands)
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.American journal of human genetics
Dietary intake is associated with risk of multiple myeloma and its precursor disease.PloS one
[Long-term survival of patients with acute myocardial infarction in Iceland].Laeknabladid
Correction: Dietary habits in adolescence and midlife and risk of breast cancer in older women.PloS one
Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants.International journal of epidemiology
Associations of Quadriceps Torque Properties with Muscle Size, Attenuation, and Intramuscular Adipose Tissue in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.Nature communications
Biofidelic finite element models for accurately classifying hip fracture in a retrospective clinical study of elderly women from the AGES Reykjavik cohort.Bone
Genetic overlap between vascular pathologies and Alzheimer's dementia and potential causal mechanisms.Alzheimer's & dementia : the journal of the Alzheimer's Association
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.Nature genetics
Association of Unrecognized Myocardial Infarction With Long-term Outcomes in Community-Dwelling Older Adults: The ICELAND MI Study.JAMA cardiology
Associations between Proportion of Plasma Phospholipid Fatty Acids, Depressive Symptoms and Major Depressive Disorder. Cross-Sectional Analyses from the AGES Reykjavik Study.The journal of nutrition, health & aging
Meta-analysis of exome array data identifies six novel genetic loci for lung function.Wellcome open research
ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals.Circulation. Genomic and precision medicine
Corrigendum: Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness.Nature medicine
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.Nature genetics
Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging.Stroke
Comparison of glomerular filtration rate estimating equations derived from creatinine and cystatin C: validation in the Age, Gene/Environment Susceptibility-Reykjavik elderly cohort.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Atrial fibrillation is associated with decreased total cerebral blood flow and brain perfusion.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studiesPlos Medicine
Cigarette smoking and hip volumetric bone mineral density and cortical volume loss in older adults: The AGES-Reykjavik study.Bone
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.Nature communications
Cardiovascular risk factors and incident giant cell arteritis: a population-based cohort study.Scandinavian journal of rheumatology
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.Nature genetics
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.Nature communications

2017

Sex hormones are negatively associated with vertebral bone marrow fat.Bone
Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.Nature communications
Midlife metabolic factors and prostate cancer risk in later life.International journal of cancer
Exome-wide association study of plasma lipids in >300,000 individuals.Nature genetics
Fibrosis as measured by the biomarker, tissue inhibitor metalloproteinase-1, predicts mortality in Age Gene Environment Susceptibility-Reykjavik (AGES-Reykjavik) Study.European heart journal
Associations of 24-hour sleep duration and CT-derived measurements of muscle and bone: The AGES-Reykjavik Study.Experimental gerontology
Associations of fat and muscle tissue with cognitive status in older adults: the AGES-Reykjavik Study.Age and ageing
Prevalence of heart failure in the elderly and future projections: the AGES-Reykjavík study.Scandinavian cardiovascular journal : SCJ
Proximal Femur Volumetric Bone Mineral Density and Mortality: 13 Years of Follow-Up of the AGES-Reykjavik Study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites.Circulation. Cardiovascular genetics
Incidence of Brain Infarcts, Cognitive Change, and Risk of Dementia in the General Population: The AGES-Reykjavik Study (Age Gene/Environment Susceptibility-Reykjavik Study).Stroke
The AGES-Reykjavik study atlases: Non-linear multi-spectral template and atlases for studies of the ageing brain.Medical image analysis
Dietary supplement use in the older population of Iceland and association with mortality.The British journal of nutrition
A novel, multiplexed targeted mass spectrometry assay for quantification of complement factor H (CFH) variants and CFH-related proteins 1-5 in human plasma.Proteomics
Novel genetic loci associated with hippocampal volume.Nature communications
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.Nature genetics
Rare and low-frequency coding variants alter human adult height.Nature
Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium.PloS one
Improvement of myocardial infarction risk prediction via inflammation-associated metabolite biomarkers.Heart (British Cardiac Society)
The complex genetics of gait speed: genome-wide meta-analysis approach.Aging
[Five decades of coronary artery disease in Iceland. Data from the Icelandic Heart Association].Laeknabladid
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.Scientific reports
Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions.Circulation
[Review of epidemiology of fractures in the Icelandic Heart Association cohort].Laeknabladid
[Heart failure among elderly Icelanders: Incidence, prevalence, underlying diseases and long-term survival].Laeknabladid
Aortic stiffness and change in glomerular filtration rate and albuminuria in older people.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Space and location of cerebral microbleeds, cognitive decline, and dementia in the community.Neurology
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.PLoS genetics
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.Nature communications
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.Nature genetics
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.Nature genetics
Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.The Journal of clinical investigation
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.Nature communications
Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.Nature genetics
Correction: The complex genetics of gait speed: genome-wide meta-analysis approach.Aging
Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data.PloS one
Heritability and genome-wide associations studies of cerebral blood flow in the general population.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Association of Triglyceride-Related Genetic Variants With Mitral Annular Calcification.Journal of the American College of Cardiology
Non-GFR Determinants of Low-Molecular-Weight Serum Protein Filtration Markers in the Elderly: AGES-Kidney and MESA-Kidney.American journal of kidney diseases : the official journal of the National Kidney Foundation
Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.Scientific reports
Discovery of novel heart rate-associated loci using the Exome Chip.Human molecular genetics
Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.International journal of epidemiology
Oral glucose tolerance test predicts increased carotid plaque burden in patients with acute coronary syndrome.PloS one
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.PLoS genetics
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.Hypertension (Dallas, Tex. : 1979)
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.Nature communications
Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology.The pharmacogenomics journal
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.Nature genetics
Reliable quantification of marrow fat content and unsaturation level using in vivo MR spectroscopy.Magnetic resonance in medicine
Frailty and Risk of Cardiovascular Diseases in Older Persons: The Age, Gene/Environment Susceptibility-Reykjavik Study.Rejuvenation research
Comparison of Summer and Winter Objectively Measured Physical Activity and Sedentary Behavior in Older Adults: Age, Gene/Environment Susceptibility Reykjavik Study.International journal of environmental research and public health
Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium.European journal of epidemiology
Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39 740 adults from 20 prospective cohort studies.The lancet. Diabetes & endocrinology
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals.Circulation. Cardiovascular genetics
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults.Lancet (London, England)
Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study.Diabetes
Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium.Scientific reports
The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypes.The European respiratory journal
Large Perivascular Spaces Visible on Magnetic Resonance Imaging, Cerebral Small Vessel Disease Progression, and Risk of Dementia: The Age, Gene/Environment Susceptibility-Reykjavik Study.JAMA neurology
Use of Repeated Blood Pressure and Cholesterol Measurements to Improve Cardiovascular Disease Risk Prediction: An Individual-Participant-Data Meta-Analysis.American journal of epidemiology
Bone disease in monoclonal gammopathy of undetermined significance: results from a screened population-based study.Blood advances
Obesity and risk of monoclonal gammopathy of undetermined significance and progression to multiple myeloma: a population-based study.Blood advances
Predictors of carotid plaque progression over a 4-year follow-up in the Reykjavik REFINE-study.Atherosclerosis
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.Nature genetics
Differential associations between retinal signs and CMBs by location: The AGES-Reykjavik Study.Neurology

2016

Novel genetic loci underlying human intracranial volume identified through genome-wide association.Nature neuroscience
Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies.The Lancet. Neurology
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.Nature genetics
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.Nature neuroscience
Vitamin D deficiency in Europe: pandemic?The American journal of clinical nutrition
Midlife Cardiovascular Risk Factors and Late-Life Unrecognized and Recognized Myocardial Infarction Detect by Cardiac Magnetic Resonance: ICELAND-MI, the AGES-Reykjavik Study.Journal of the American Heart Association
Association Between Interstitial Lung Abnormalities and All-Cause Mortality.JAMA
Interactive graph-cut segmentation for fast creation of finite element models from clinical ct data for hip fracture prediction.Computer methods in biomechanics and biomedical engineering
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index.Molecular psychiatry
Physical activity and incidence of sarcopenia: the population-based AGES-Reykjavik Study.Age and ageing
Genome-wide association study identifies 74 loci associated with educational attainment.Nature
An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group.Genetic epidemiology
Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness.Nature medicine
Associations between arterial stiffness, depressive symptoms and cerebral small vessel disease: cross-sectional findings from the AGES-Reykjavik Study.Journal of psychiatry & neuroscience : JPN
Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies.PLoS genetics
High-Sensitivity Cardiac Troponin I Is a Strong Predictor of Cardiovascular Events and Mortality in the AGES-Reykjavik Community-Based Cohort of Older Individuals.Clinical chemistry
Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium.PloS one
Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease.Science (New York, N.Y.)
Occupation as a risk factor for renal cell cancer: a nationwide, prospective epidemiological study.Scandinavian journal of urology
Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium.PloS one
Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.Journal of medical genetics
Mortality in Older Persons with Retinopathy and Concomitant Health Conditions: The Age, Gene/Environment Susceptibility-Reykjavik Study.Ophthalmology
Late-life brain volume: a life-course approach. The AGES-Reykjavik study.Neurobiology of aging
Influence of Day Length and Physical Activity on Sleep Patterns in Older Icelandic Men and Women.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
Incidence and prevalence of total joint replacements due to osteoarthritis in the elderly: risk factors and factors associated with late life prevalence in the AGES-Reykjavik Study.BMC musculoskeletal disorders
Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals.Alzheimer's & dementia : the journal of the Alzheimer's Association
Exploring potential mortality reductions in 9 European countries by improving diet and lifestyle: A modelling approach.International journal of cardiology
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.Nature communications
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.Nature communications
Comparison of Handgrip and Leg Extension Strength in Predicting Slow Gait Speed in Older Adults.Journal of the American Geriatrics Society
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.Journal of the American Society of Nephrology : JASN
Early Life Residence, Fish Consumption, and Risk of Breast Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Cardiac and Carotid Markers Link With Accelerated Brain Atrophy: The AGES-Reykjavik Study (Age, Gene/Environment Susceptibility-Reykjavik).Arteriosclerosis, thrombosis, and vascular biology
Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group.The pharmacogenomics journal
Genetic Obesity and the Risk of Atrial Fibrillation: Causal Estimates from Mendelian Randomization.Circulation
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.American journal of human genetics
Imminent risk of fracture after fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.Journal of medical genetics
Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study.Human molecular genetics
Determinants of outcome of vocational rehabilitation.Work (Reading, Mass.)
Gene-gene Interaction Analyses for Atrial Fibrillation.Scientific reports
Long-Term Hormone Replacement Therapy Is Associated with Low Coronary Artery Calcium Levels in a Cohort of Older Women: The Age, Gene/Environment Susceptibility-Reykjavik Study.Journal of the American Geriatrics Society
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants.Lancet (London, England)
Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.Circulation. Cardiovascular genetics
Prevalence and determinants of carotid plaque in the cross-sectional REFINE-Reykjavik study.BMJ open
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference.Proceedings of the National Academy of Sciences of the United States of America
Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.Nature genetics
Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis.The lancet. Diabetes & endocrinology
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.Nature genetics
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.Nature genetics
52 Genetic Loci Influencing Myocardial Mass.Journal of the American College of Cardiology
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.PLoS genetics
Genetic variants linked to education predict longevity.Proceedings of the National Academy of Sciences of the United States of America
Association of bone turnover markers with volumetric bone loss, periosteal apposition, and fracture risk in older men and women: the AGES-Reykjavik longitudinal study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.PLoS genetics
Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits.Nature genetics
Pineal Gland Volume Assessed by MRI and Its Correlation with 6-Sulfatoxymelatonin Levels among Older Men.Journal of biological rhythms
A century of trends in adult human height.eLife
Airflow obstruction, atherosclerosis and cardiovascular risk factors in the AGES Reykjavik study.Atherosclerosis
Allometric scaling of brain regions to intra-cranial volume: An epidemiological MRI study.Human brain mapping
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.Journal of medical genetics
Seasonal Changes in Vitamin D-Effective UVB Availability in Europe and Associations with Population Serum 25-Hydroxyvitamin D.Nutrients
GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.Aging cell
Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease.Journal of Alzheimer's disease : JAD
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.American journal of human genetics
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.American journal of human genetics
Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.American journal of human genetics
Measurement of Circulating Phospholipid Fatty Acids: Association between Relative Weight Percentage and Absolute Concentrations.Journal of the American College of Nutrition
Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.Nature genetics
Post-stroke bacteriuria among stroke patients attending a physiotherapy clinic in Ghana: a cross-sectional study.Therapeutics and clinical risk management
Shared genetic contribution to Ischaemic Stroke and Alzheimer's Disease.Annals of neurology

2015

Directional dominance on stature and cognition in diverse human populations.Nature
PLD3 variants in population studies.Nature
Overweight and Obesity in Midlife and Brain Structure and Dementia 26 Years Later: The AGES-Reykjavik Study.American journal of epidemiology
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysisLancet Diabetes & Endocrinology
Cerebrovascular Damage Mediates Relations Between Aortic Stiffness and Memory.Hypertension (Dallas, Tex. : 1979)
Left-right differences in the proximal femur's strength of post-menopausal women: a multicentric finite element study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Are bone turnover markers associated with volumetric bone density, size, and strength in older men and women? The AGES-Reykjavik study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes.Diabetes
Muscle Quality and Myosteatosis: Novel Associations With Mortality Risk: The Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study.American journal of epidemiology
Feasibility of Using Pseudo-Continuous Arterial Spin Labeling Perfusion in a Geriatric Population at 1.5 Tesla.PloS one
Depression and serum 25-hydroxyvitamin D in older adults living at northern latitudes - AGES-Reykjavik Study.Journal of nutritional science
Association of change in brain structure to objectively measured physical activity and sedentary behavior in older adults: Age, Gene/Environment Susceptibility-Reykjavik Study.Behavioural brain research
Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.Nature
Molecular mechanisms underlying variations in lung function: a systems genetics analysis.The Lancet. Respiratory medicine
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.Nature genetics
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.PLoS genetics
White Matter Lesion Progression: Genome-Wide Search for Genetic Influences.Stroke
Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.PloS one
Prevalence and complications of chronic kidney disease in a representative elderly population in Iceland.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
The Association Between Midlife Physical Activity and Depressive Symptoms in Late Life: Age Gene/Environment Susceptibility-Reykjavik Study.The journals of gerontology. Series A, Biological sciences and medical sciences
Hearing in older adults with exfoliation syndrome/exfoliation glaucoma or primary open-angle glaucoma.Acta ophthalmologica
Salivary cortisol, brain volumes, and cognition in community-dwelling elderly without dementia.
GWAS for executive function and processing speed suggests involvement of the CADM2 gene.
Carotid arterial stiffness and risk of incident cerebral microbleeds in older people: the Age, Gene/Environment Susceptibility (AGES)-Reykjavik study.
Cod liver oil consumption at different periods of life and bone mineral density in old age.
Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease.
Comparing GFR Estimating Equations Using Cystatin C and Creatinine in Elderly IndividualsJournal of the American Society of Nephrology
Convergent genetic and expression data implicate immunity in Alzheimer's diseaseAlzheimers & Dementia
Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology ConsortiumBiological Psychiatry
Carotid Atherosclerotic Plaque Burden Is Increased in Patients with Acute Coronary Syndrome Compared with Normal PopulationCardiology
Cerebral Small Vessel Disease and Association With Higher Incidence of Depressive Symptoms in a General Elderly Population: The AGES-Reykjavik StudyAmerican Journal of Psychiatry
Increased Carotid Plaque Burden in Patients with Acute Coronary Syndrome and Impaired Glucose MetabolismCardiology
Circulating Brain-Derived Neurotrophic Factor Concentrations and the Risk of Cardiovascular Disease in the CommunityJournal of the American Heart Association
Prediabetes and Diabetes Are Not Related to Endothelial Dysfunction among Patients with Unstable Coronary SyndromesCardiology
Sex-specific predictors of hearing-aid use in older persons: The age, gene/environment susceptibility - Reykjavik study.International journal of audiology
Relations Between Aortic Stiffness and Left Ventricular Structure and Function in Older Participants in the Age, Gene/Environment Susceptibility-Reykjavik StudyCirculation-Cardiovascular Imaging
Urinary Melatonin Levels, Sleep Disruption, and Risk of Prostate Cancer in Elderly MenEuropean Urology
Muscle Quality and Muscle Fat Infiltration in Relation to Incident Mobility Disability and Gait Speed Decline: the Age, Gene/Environment Susceptibility-Reykjavik Study.The journals of gerontology. Series A, Biological sciences and medical sciences
Polyunsaturated fatty acids in relation to incident mobility disability and decline in gait speed; the Age, Gene/Environment Susceptibility-Reykjavik StudyEuropean Journal of Clinical Nutrition
Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in HumansPlos One
Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRICirculation-Cardiovascular Genetics
Mediation Analysis of Aortic Stiffness and Renal Microvascular FunctionJournal of the American Society of Nephrology
Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adultsObesity Reviews
INCIDENCE AND PREVALENCE OF TOTAL JOINT REPLACEMENTS DUE TO OSTEOARTHRITIS IN THE ELDERLY: RISK FACTORS AND FACTORS ASSOCIATED WITH LATE LIFE PREVALENCE. THE AGES-REYKJAVIK STUDYOsteoarthritis and Cartilage
Genome-wide association study of kidney function decline in individuals of European descentKidney International
Genetically Determined Height and Coronary Artery DiseaseNew England Journal of Medicine
GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 CandidacyJournals of Gerontology Series a-Biological Sciences and Medical Sciences
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibilityNature Communications
Genetic studies of body mass index yield new insights for obesity biologyNature
Fat Distribution and Mortality: The AGES-Reykjavik StudyObesity
Covariate-adjusted measures of discrimination for survival dataBiometrical Journal
Circadian clock genes and risk of fatal prostate cancerCancer Causes & Control
Risk Factors Associated With Incident Cerebral Microbleeds According to Location in Older People: The Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study.
Integrative Pathway Genomics of Lung Function and Airflow Obstruction.
Physical Activity from Early Adulthood and Risk of Prostate Cancer: A 24-Year Follow-Up Study among Icelandic Men.
Co-Presence of Multimorbidity and Disability with Frailty: An Examination of Heterogeneity in the Frail Older Population.The Journal of frailty & aging
Midlife Blood Pressure and Late-Life GFR and Albuminuria: An Elderly General Population Cohort.
Fish and fish-liver oil consumption in adolescence and midlife and risk of CHD in older women.
Segmental Kidney Volumes Measured by Dynamic Contrast-Enhanced Magnetic Resonance Imaging and Their Association With CKD in Older PeopleAmerican Journal of Kidney Diseases
Plasma phospholipid fatty acids and fish-oil consumption in relation to osteoporotic fracture risk in older adults: the Age, Gene/Environment Susceptibility StudyAmerican Journal of Clinical Nutrition
Lifetime Risk of Stage 3-5 CKD in a Community-Based Sample in Iceland.
N-terminal pro-brain natriuretic peptide and abnormal brain aging: The AGES-Reykjavik Study.
Aortic Stiffness and Kidney Disease in an Elderly PopulationAmerican Journal of Nephrology
Cardiac Hemodynamics are Linked With Structural and Functional Features of Brain Aging: The Age, Gene/Environment Susceptibility (AGES)-Reykjavik StudyJournal of the American Heart Association
Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C.NPJ aging and mechanisms of disease
Novel Genetic Loci Associated With Retinal Microvascular Diameter.Circulation. Cardiovascular genetics
Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis.The lancet. Diabetes & endocrinology
A novel Alzheimer disease locus located near the gene encoding tau protein.Molecular psychiatry
Relations between aortic stiffness and left ventricular structure and function in older participants in the Age, Gene/Environment Susceptibility--Reykjavik Study.Circulation. Cardiovascular imaging
New genetic loci link adipose and insulin biology to body fat distribution.Nature
Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI.Circulation. Cardiovascular genetics
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).Molecular psychiatry
Biological interpretation of genome-wide association studies using predicted gene functions.Nature communications
Common genetic variants influence human subcortical brain structures.Nature
Cardiac hemodynamics are linked with structural and functional features of brain aging: the age, gene/environment susceptibility (AGES)-Reykjavik Study.Journal of the American Heart Association
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.Nature genetics
Higher Plasma Phospholipid n-3 PUFAs, but Lower n-6 PUFAs, Are Associated with Lower Pulse Wave Velocity among Older Adults.The Journal of nutrition
Carotid atherosclerosis and cardiovascular health metrics in old subjects from the AGES-Reykjavik study.Atherosclerosis
The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.Molecular psychiatry

2014

Glycated Hemoglobin Measurement and Prediction of Cardiovascular DiseaseJama-Journal of the American Medical Association
Impairments in hearing and vision impact on mortality in older people: the AGES-Reykjavik StudyAge and Ageing
Gene-Age Interactions in Blood Pressure Regulation: A Large-Scale Investigation with the CHARGE, Global BPgen, and ICBP ConsortiaAmerican Journal of Human Genetics
Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortiumHuman Molecular Genetics
Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and BlacksAmerican Journal of Human Genetics
Fracture Risk Assessment in Older Adults Using a Combination of Selected Quantitative Computed Tomography Bone Measures: A Subanalysis of the Age, Gene/Environment Susceptibility-Reykjavik StudyJournal of Clinical Densitometry
Hip Fractures and Bone Mineral Density in the Elderly-Importance of Serum 25-Hydroxyvitamin DPlos One
Serum Carboxymethyllysine, an Advanced Glycation End Product, and Age-Related Macular Degeneration The Age, Gene/Environment Susceptibility-Reykjavik StudyJama Ophthalmology
Genetic diversity is a predictor of mortality in humansBmc Genetics
Integrating Genetic, Transcriptional, and Functional Analyses to Identify 5 Novel Genes for Atrial FibrillationCirculation
Plasma phospholipid PUFAs are associated with greater muscle and knee extension strength but not with changes in muscle parameters in older adults.The Journal of nutrition
Proximal Femur Strength and Cortical Thickness Estimates in Klinefelter Syndrome and Post-Menopausal WomenJournal of Bone and Mineral Research
The Challenges of Genome-Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood LevelsPlos One
Structural MRI correlates of apathy symptoms in older persons without dementia AGES-Reykjavik StudyNeurology
The biomarker tissue inhibitor of metalloproteinase-1 (TIMP-1) is an independent predictor of all-cause mortality in the AGES-Reykjavik studyEuropean Heart Journal
The prevalence of aortic stenosis in the elderly in Iceland and predictions for the coming decades: The AGES-Reykjavik studyInternational Journal of Cardiology
The Alcohol Paradox: Light-to-Moderate Alcohol Consumption, Cognitive Function, and Brain VolumeJournals of Gerontology Series a-Biological Sciences and Medical Sciences
A blunted diurnal cortisol response in the lower educated does not explain educational differences in coronary heart disease: findings from the AGES-Reykjavik study.Social science & medicine (1982)
Prediction of the prevalence of aortic stenosis in the elderly in Iceland in the future: The AGES-Reykjavik studyEuropean Heart Journal
Spousal Loss and Cognitive Function in Later Life: A 25-year Follow-up in the AGES-Reykjavik StudyAmerican Journal of Epidemiology
Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL CholesterolAmerican Journal of Human Genetics
Trans-ethnic meta-analysis of white blood cell phenotypesHuman Molecular Genetics
The incidence of a first major osteoporotic fracture in Iceland and implications for FRAXOsteoporosis International
Midlife Determinants Associated with Sedentary Behavior in Old AgeMedicine and Science in Sports and Exercise
Age-related macular degeneration and mortality in community-dwelling elders: the age, gene/environment susceptibility Reykjavik study.Ophthalmology
Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study.Molecular psychiatry
Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung FunctionPlos One
Assessment of Incident Spine and Hip Fractures in Women and Men Using Finite Element Analysis of CT ScansJournal of Bone and Mineral Research
Association of Low-Density Lipoprotein Cholesterol-Related Genetic Variants With Aortic Valve Calcium and Incident Aortic StenosisJama-Journal of the American Medical Association
Adipose Tissue Density, a Novel Biomarker Predicting Mortality Risk in Older AdultsJournals of Gerontology Series a-Biological Sciences and Medical Sciences
Adipose Tissue, Muscle, and Function: Potential Mediators of Associations Between Body Weight and Mortality in Older Adults With Type 2 DiabetesDiabetes Care
Assessing Risk Prediction Models Using Individual Participant Data From Multiple StudiesAmerican Journal of Epidemiology
Milk consumption throughout life and bone mineral content and density in elderly men and womenOsteoporosis International
Movement during sedentary time is associated with metabolic outcomesDiabetologia
MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE (MGUS) IS ASSOCIATED WITH A 30% INCREASED RISK OF DYING AT 8 YEARS OF FOLLOW-UP: RESULTS FROM A SCREENED CROSS-SECTIONAL POPULATION-BASED STUDYHaematologica
B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studiesEuropace
Midlife migraine and late-life parkinsonism: AGES-Reykjavik study.Neurology
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarcheNature
Birth Size and Brain Function 75 Years LaterPediatrics
Novel Genetic Markers Associate With Atrial Fibrillation Risk in Europeans and JapaneseJournal of the American College of Cardiology
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statinsNature Communications
Genome-wide association analysis identifies six new loci associated with forced vital capacityNature Genetics
Midlife migraine and late-life parkinsonism AGES-Reykjavik StudyNeurology
Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT intervalPharmacogenomics Journal
New insight into the obesity paradox among older adults with diabetesFaseb Journal
CHANGES IN TOTAL CHOLESTEROL LEVELS IN THE ICELANDIC POPULATION ARE NOT RELATED TO STATIN, BUT RATHER DIETARY FACTORSCardiology
Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysisEuropean Heart Journal
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarizationNature Genetics
Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's DiseasePlos One
Circulating Sclerostin Associated With Vertebral Bone Marrow Fat in Older Men But Not WomenJournal of Clinical Endocrinology & Metabolism
Joint effect of mid- and late-life blood pressure on the brain The AGES-Reykjavik StudyNeurology
Population Assessment of Future Trajectories in Coronary Heart Disease MortalityPlos One
Five-Year Incidence, Progression, and Risk Factors for Age-Related Macular Degeneration The Age, Gene/Environment Susceptibility StudyOphthalmology
Is There a Sex Difference in Accelerometer Counts During Walking in Older Adults?Journal of Physical Activity & Health
Prognosis of atypical late gadolinium enhancement by cardiovascular MR in older adults in the ICELAND-MI studyEuropean Heart Journal
Community awareness of stroke in Accra, GhanaBmc Public Health
Cardiovascular Risk Factors and Incident Giant Cell Arteritis.Arthritis & Rheumatology
Profile and health-related quality of life of Ghanaian stroke survivorsClinical Interventions in Aging
Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass IndexPlos Genetics
Mediation analysis of aortic stiffness and renal microvascular function.Journal of the American Society of Nephrology : JASN
Defining the role of common variation in the genomic and biological architecture of adult human height.Nature genetics
Multi-ethnic fine-mapping of 14 central adiposity lociHuman Molecular Genetics
ASSOCIATION OF BRAIN ANATOMY WITH PHYSICAL ACTIVITY AND SEDENTARY BEHAVIOR IN OLDER ICELANDERSGerontologist
Carotid plaque burden is related to impaired glucose metabolism among patients with acute coronary syndromesEuropean Heart Journal
Novel Genetic Approach to Investigate the Role of Plasma Secretory Phospholipase A2 (sPLA(2))-V Isoenzyme in Coronary Heart Disease Modified Mendelian Randomization Analysis Using PLA2G5 Expression LevelsCirculation-Cardiovascular Genetics
Obesity and Risk of Monoclonal Gammopathy of Undetermined Significance: A Population-Based StudyBlood
Muscle mass and adiposity, muscle strength, and physical performance vary by gender as risk factors for hip fracture: the Age Gene/Environment Susceptibility Study-ReykjavikJournal of Bone and Mineral Research
Longitudinal and circumferential strain of the proximal aorta.Journal of the American Heart Association
Circadian dysrhythm and advanced prostate cancerJournal of Clinical Oncology
Quality control and conduct of genome-wide association meta-analysesNature Protocols
Diabetes, Markers of Brain Pathology and Cognitive Function: The Age, Gene/Environment Susceptibility-Reykjavik StudyAnnals of Neurology
Brain Volume as an Integrated Marker for the Risk of Death in a Community-Based Sample: Age Gene/Environment Susceptibility--Reykjavik Study.The journals of gerontology. Series A, Biological sciences and medical sciences
Pulse Pressure Relation to Aortic and Left Ventricular Structure in the Age, Gene/Environment Susceptibility (AGES)-Reykjavik StudyHypertension
Epidemiology of fractures in Iceland and secular trends in major osteoporotic fractures 1989-2008Osteoporosis International
Effects of Long-Term Averaging of Quantitative Blood Pressure Traits on the Detection of Genetic AssociationsAmerican Journal of Human Genetics
Faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortalityNutrition Metabolism and Cardiovascular Diseases
Different susceptibility of medial temporal lobe and basal ganglia atrophy rates to vascular risk factorsNeurobiology of Aging
Does cardioversion of atrial fibrillation improve cerebral blood flow?European Heart Journal
Do Contralateral Femora Differ in Strength? A Multicentric Finite Element Study in Post-menopausal Women.Journal of Bone and Mineral Research

2013

Association of heat shock proteins with all-cause mortalityAge
WALKING, STRENGTH TRAINING, AND NUTRITION COUNSELLING IMPROVES PHYSICAL HEALTH IN OLDER ADULTSGerontologist
Copy Number Variations in Alternative Splicing Gene Networks Impact LifespanPlos One
Genetic Associations with Valvular Calcification and Aortic StenosisNew England Journal of Medicine
Similar decline in mortality rate of older persons with and without type 2 diabetes between 1993 and 2004 the Icelandic population-based Reykjavik and AGES-Reykjavik cohort studiesBmc Public Health
Proximal femoral density distribution and structure in relation to age and hip fracture risk in womenJournal of Bone and Mineral Research
Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer's DiseaseCell
Prevalence of Airflow Obstruction in Nonsmoking Older Individuals Using Different Spirometric Criteria: The AGES Reykjavik StudyCopd-Journal of Chronic Obstructive Pulmonary Disease
Objective measurements of daily physical activity patterns and sedentary behaviour in older adults: Age, Gene/Environment Susceptibility-Reykjavik StudyAge and Ageing
Testing reported SNPs for cortical and trabecular vBMD for hip and spine in the Age, Gene/Environment Susceptibility-Reykjavik StudyJournal of Bone and Mineral Research
Mining the Human Phenome Using Allelic Scores That Index Biological IntermediatesPlos Genetics
[Health policy interventions: the pathway to public health].Laeknabladid
TOTAL JOINT REPLACEMENT DUE TO OSTEOARTHRITIS: THE EFFECT OF OCCUPATIONAL HISTORY, EDUCATION AND PHYSICAL ACTIVITY. THE AGES-REYKJAVIK STUDYOsteoarthritis and Cartilage
Haplotype analysis of the folate-related genes MTHFR, MTRR, and MTR and migraine with auraCephalalgia
Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE ConsortiumPlos One
Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease RiskHypertension
Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signalingJournal of Clinical Investigation
Consumption of Fish Products across the Lifespan and Prostate Cancer RiskPlos One
Atrial Fibrillation is Associated With Reduced Brain Volume and Cognitive Function Independent of Cerebral InfarctsStroke
Changes in total cholesterol levels in Western societies are not related to statin, but rather dietary factors: the example of the Icelandic populationEuropean Heart Journal
N-terminal pro-B-type natriuretic peptide and the prediction of primary cardiovascular events: results from 15-year follow-up of WOSCOPSEuropean Heart Journal
GWAS meta-analysis of vertebral trabecular volumetric BMD by QCTJournal of Bone and Mineral Research
The genetic basis of cross-phenotype correlation with bone fracture risk: the GEFOS consortiumJournal of Bone and Mineral Research
The effects of 6 months' multimodal training on functional performance, strength, endurance, and body mass index of older individuals. Are the benefits of training similar among women and men?Laeknabladid
Are C-Reactive Protein Associated Genetic Variants Associated with Serum Levels and Retinal Markers of Microvascular Pathology in Asian Populations from Singapore?Plos One
Type 3 finger length pattern is associated with total knee replacements due to osteoarthritis but not with hip replacements or hand osteoarthritis in the elderly: The AGES-Reykjavik studyBmc Musculoskeletal Disorders
The Molecular Genetic Architecture of Self-EmploymentPlos One
The shared allelic architecture of adiponectin levels and coronary artery diseaseAtherosclerosis
Vertebral Bone Marrow Fat Associated With Lower Trabecular BMD and Prevalent Vertebral Fracture in Older AdultsJournal of Clinical Endocrinology & Metabolism
Secular Trends in the Incidence of First Hip, Clinical Vertebral, Distal forearm and Proximal Humerus Fractures in Icelandic Men and Women in 1989-2008Journal of Bone and Mineral Research
Systemic inflammation and cardiovascular disease in chronic obstructive pulmonary disease (COPD)European Respiratory Journal
Socioeconomic factors from midlife predict mobility limitation and depressed mood three decades later; Findings from the AGES-Reykjavik StudyBmc Public Health
Structural patterns of the proximal femur in relation to age and hip fracture risk in womenBone
Similarities and Differences Between Sexes in Regional Loss of Cortical and Trabecular Bone in the Mid-Femoral Neck: The AGES-Reykjavik Longitudinal StudyJournal of Bone and Mineral Research
Sleep Disruption Among Older Men and Risk of Prostate CancerCancer Epidemiology Biomarkers & Prevention
Simple Risk Model Predicts Incidence of Atrial Fibrillation in a Racially and Geographically Diverse Population: the CHARGE-AF ConsortiumJournal of the American Heart Association
OSTEOPOROSIS AND BONE MINERAL DENSITY ARE ASSOCIATED WITH AORTIC VALVE CALCIFICATION: THE AGE, GENE-ENVIRONMENT SUSCEPTIBILITY (AGES)-REYKJAVIK STUDYJournal of Investigative Medicine
N-terminal pro-B-type natriuretic peptide and the prediction of primary cardiovascular events: results from 15-year follow-up of WOSCOPS (vol 34, pg 443, 2013)European Heart Journal
Psoriatic Arthritis and Mortality-a Nationwide StudyArthritis and Rheumatism
Persistence of the effect of birth size on dysglycaemia and type 2 diabetes in old age: AGES-Reykjavik StudyAge
Multiethnic Meta-Analysis of Genome-Wide Association Studies in > 100 000 Subjects Identifies 23 FibrinogenAssociated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular DiseaseCirculation
MILK CONSUMPTION THROUGHOUT LIFE IS ASSOCIATED WITH BONE MINERAL DENSITY IN ELDERLY MEN AND WOMENAnnals of Nutrition and Metabolism
Is atrial fibrillation associated with a decrease in total brain perfusion?European Heart Journal
Midlife Physical Activity Preserves Lower Extremity Function in Older Adults: Age Gene/Environment Susceptibility-Reykjavik StudyJournal of the American Geriatrics Society
Lack of association between the MTHFR C677T variant and migraine with aura in an older population: Could selective survival play a role?Cephalalgia
Migraine, depression, and brain volume The AGES-Reykjavik StudyNeurology
Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium ConcentrationsPlos Genetics
Meta-analysis of Gene-Level Associations for Rare Variants Based on Single-Variant StatisticsAmerican Journal of Human Genetics
How to Adjust the Overestimate of the Incidence of Major Osteporotic Fracture When Using Summary DataJournal of Bone and Mineral Research
Health policy interventions: The pathway to public healthLaeknabladid
Hypothalamic-Pituitary-Adrenal Axis Activity and Regional Brain Volumes in Community-Dwelling Older Persons: The Ages-Reykjavik StudyBiological Psychiatry
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposityHuman Molecular Genetics
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 regionAnnals of the Rheumatic Diseases
Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-AnalysisPlos One
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disordersNature Genetics
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architectureNature Genetics
Genome Wide Association Analysis of a Founder Population Identified TAF3 as a Gene for MCHC in HumansPlos One
Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortiaHuman Molecular Genetics
Genetic Loci for Retinal Arteriolar MicrocirculationPlos One
Genome-Wide Association Study of Retinopathy in Individuals without DiabetesPlos One
Genetic variation associated with circulating monocyte count in the eMERGE NetworkHuman Molecular Genetics
Genome-wide association analyses identify 18 new loci associated with serum urate concentrationsNature Genetics
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational AttainmentScience
Functional characterization of GWAS loci associated with fracture riskJournal of Bone and Mineral Research
Early peak height velocity and cardiovascular disease mortality among Icelandic womenAnnals of Medicine
Effects of exercise training and nutrition counseling on body composition and cardiometabolic factors in old individualsEuropean Geriatric Medicine
Effect of finite element model loading condition on fracture risk assessment in men and women: The AGES-Reykjavik studyBone
Dysfunctional nitric oxide signalling increases risk of myocardial infarctionNature
Discovery and refinement of loci associated with lipid levelsNature Genetics
Common variants at 12q15 and 12q24 are associated with infant head circumference (vol 44, pg 532, 2012)Nature Genetics
Common variants at 6q22 and 17q21 are associated with intracranial volume (vol 44, pg 539, 2012)Nature Genetics
CRP is associated with lung function decline in men but not women: A prospective studyRespiratory Medicine
Common Variants in Mendelian Kidney Disease Genes and Their Association with Renal FunctionJournal of the American Society of Nephrology
Candidate Gene Association Study of BMI-Related Loci, Weight, and Adiposity in Old AgeJournals of Gerontology Series a-Biological Sciences and Medical Sciences
Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple CohortsPlos Medicine
Bone Mineral Density (BMD), Vertebral Marrow Fat, and Markers of Metabolism in Older Men and Women: Results from the AGES-BMA studyJournal of Bone and Mineral Research
COAGULATION RISK FACTORS IN CEREBRAL MICROBLEEDSAND CEREBRAL INFARCTION. THE AGES REYKJAVIK STUDY.International Journal of Laboratory Hematology
CORONARY ARTERY CALCIUM AND PHYSICAL PERFORMANCE AS DETERMINANTS OF MORTALITY: AGES-REYKJAVIK STUDYGerontologist
Associations of current and remitted major depressive disorder with brain atrophy: the AGES-Reykjavik StudyPsychological Medicine
Association of Type D personality with unhealthy lifestyle, and estimated risk of coronary events in the general Icelandic populationEuropean Journal of Preventive Cardiology
Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European DescentAmerican Journal of Epidemiology
A genome-wide association study of early menopause and the combined impact of identified variantsHuman Molecular Genetics
A Genome-Wide Association Study of Depressive SymptomsBiological Psychiatry
[The effects of 6 months' multimodal training on functional performance, strength, endurance, and body mass index of older individuals. Are the benefits of training similar among women and men?].Laeknabladid
Hemostatic Factors and Risk of Coronary Heart Disease in General Populations: New Prospective Study and Updated Meta-AnalysesPlos One
Coronary artery calcium and physical performance as determinants of mortality in older age: The AGES-Reykjavik StudyInternational Journal of Cardiology
Large-scale association analysis identifies new risk loci for coronary artery diseaseNature Genetics
Common variants associated with plasma triglycerides and risk for coronary artery diseaseNature Genetics
Genetic Variation at NCAN Locus Is Associated with Inflammation and Fibrosis in Non-Alcoholic Fatty Liver Disease in Morbid ObesityHuman Heredity
Serum Vitamin D and Parathyroid Hormone in Relation to Cardiac Structure and Function: The ICELAND-MI Substudy of AGES-ReykjavikJournal of Clinical Endocrinology & Metabolism
The Age-Specific Quantitative Effects of Metabolic Risk Factors on Cardiovascular Diseases and Diabetes: A Pooled AnalysisPlos One
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's diseaseNature Genetics
Pulmonary Function Impairment May Be an Early Risk Factor for Late-Life Cognitive ImpairmentJournal of the American Geriatrics Society
ATP5H/KCTD2 locus is associated with Alzheimer's disease risk.Molecular psychiatry
Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart DiseasePlos One
EARLY PEAK HEIGHT VELOCITY IS ASSOCIATED WITH CARDIOVASCULAR DISEASE MORTALITY IN A COHORT OF ICELANDIC WOMENAnnals of Nutrition and Metabolism

2012

Effect of Birth Year on Birth Weight and Obesity in Adulthood: Comparison between Subjects Born Prior to and during the Great Depression in IcelandPlos One
Common variants at 6q22 and 17q21 are associated with intracranial volumeNature Genetics
Brain tissue volumes by APOE genotype and leisure activity-the AGES-Reykjavik StudyNeurobiology of Aging
B-Type-Natriuretic Peptide and C-Reactive Protein in the Prediction of Atrial Fibrillation Risk: The CHARGE-AF ConsortiumCirculation
Cerebral microbleeds and age-related macular degeneration: the AGES-Reykjavik StudyNeurobiology of Aging
A framework for quantifying net benefits of alternative prognostic modelsStatistics in Medicine
Age-related loss of proximal femoral strength in elderly men and women: The Age Gene/Environment Susceptibility Study - ReykjavikBone
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistanceNature Genetics
C-Reactive Protein, Fibrinogen, and Cardiovascular Disease PredictionNew England Journal of Medicine
Brain tissue volumes in the general population of the elderly The AGES-Reykjavik StudyNeuroimage
Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid ConcentrationsPlos Genetics
Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney FunctionPlos Genetics
Genome-Wide Association Studies Identify CHRNA5/3 and HTR4 in the Development of Airflow ObstructionAmerican Journal of Respiratory and Critical Care Medicine
CROSS-VALIDATION OF NEW CUT-OFF VALUES FOR HIGH-RISK WAIST CIRCUMFERENCE IN OLDER ADULTS: RESULTS FROM FOUR COHORT STUDIESAge and Ageing
Common variants at 12q14 and 12q24 are associated with hippocampal volumeNature Genetics
Validated SNPs for eGFR and their associations with albuminuriaHuman Molecular Genetics
The Promises and Pitfalls of GenoeconomicsAnnual Review of Economics, Vol 4
Prevalence and Prognosis of Unrecognized Myocardial Infarction Determined by Cardiac Magnetic Resonance in Older AdultsJama-Journal of the American Medical Association
FTO genotype is associated with phenotypic variability of body mass indexNature
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studiesLancet
Evaluation of the postural stability of elderly persons using time domain signal analysisJournal of Vestibular Research-Equilibrium & Orientation
Early life residency associated with the risk of developing type 2 diabetes - The population-based Reykjavik StudyLaeknabladid
Lifelong physical activity in maintaining bone strength in older men and women of the Age, Gene/Environment Susceptibility-Reykjavik StudyOsteoporosis International
[Chronic non-communicable diseases: a global epidemic of the 21st century].Laeknabladid
Selective Survival and Late-Life Risk Factor StudiesNeurology
Serum levels of marine-derived n-3 fatty acids in Icelanders, Japanese, Koreans, and Americans-A descriptive epidemiologic studyProstaglandins Leukotrienes and Essential Fatty Acids
Genome-wide meta-analysis of common variant differences between men and womenHuman Molecular Genetics
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney functionHuman Molecular Genetics
Retinopathy in old persons with and without diabetes mellitus: the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-R)Diabetologia
Common Genetic Variation in the 3 '-BCL11B Gene Desert Is Associated With Carotid-Femoral Pulse Wave Velocity and Excess Cardiovascular Disease Risk The AortaGen ConsortiumCirculation-Cardiovascular Genetics
Identification of common variants associated with human hippocampal and intracranial volumesNature Genetics
The use of digital photographs for the diagnosis of hand osteoarthritis: the AGES-Reykjavik studyBmc Musculoskeletal Disorders
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fractureNature Genetics
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery diseaseNature Genetics
Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysisInternational Journal of Epidemiology
Common variants at 12q15 and 12q24 are associated with infant head circumferenceNature Genetics
Heterogeneity in White Blood Cells Has Potential to Confound DNA Methylation MeasurementsPlos One
LOW SERUM CONCENTRATIONS OF SERUM VEGF-R2 IN ELDERLY FEMALES WITH THUMB BASE OSTEOARTHRITIS: THE AGES-REYKJAVIK STUDY.Osteoarthritis and Cartilage
[Early life residency associated with the risk of developing type 2 diabetes - the population-based Reykjavík study].Laeknabladid
Genetic, physiological, and lifestyle predictors of mortality in the general population.American journal of public health
PERSISTENCE OF THE EFFECT OF BODY SIZE AT BIRTH ON DYSGLYCAEMIA AND TYPE 2 DIABETES IN OLD AGE: AGES-REYKJAVIK STUDYGerontologist
THE ASSOCIATION BETWEEN MID-LIFE PHYSICAL ACTIVITY AND LOWER EXTREMITY FUNCTION IN OLDER ADULTS: ROLE OF COGNITIVE FUNCTION, AGE GENE/ENVIRONMENT SUSCEPTIBILITY (AGES) - REYKJAVIK STUDYGerontologist
Rye bread consumption in early life and reduced risk of advanced prostate cancerCancer Causes & Control
The Joint Association of Migraine and Depression with Brain Volume: The AGES-Reykjavik StudyNeurology
Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 IndividualsPlos Genetics
Major Depressive Disorder, Salivary Cortisol, and Brain Atrophy in a Population-Based Cohort of Old Persons without Dementia. The AGES-Reykjavik StudyBiological Psychiatry
Mid-Thigh Cortical Bone Structural Parameters, Muscle Mass and Strength, and Association with Lower Limb Fractures in Older Men and Women (AGES-Reykjavik Study)Calcified Tissue International
Milk Intake in Early Life and Risk of Advanced Prostate CancerAmerican Journal of Epidemiology
Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortiumHuman Genetics
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populationsNature Genetics
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathwaysNature Genetics
Lipid-Related Markers and Cardiovascular Disease PredictionJama-Journal of the American Medical Association
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathwaysNature Genetics
Meta-analysis identifies six new susceptibility loci for atrial fibrillationNature Genetics
Insomnia among elderly men and risk of prostate cancerJournal of Clinical Oncology
Incidence and Progression of Aortic Valve Calcification among the Elderly: a Prospective Analysis of the Age, Gene-Environment Susceptibility (AGES)-Reykjavik StudyCirculation
Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik studyAge and Ageing
Effects of a 6-month multimodal training intervention on retention of functional fitness in older adults: A randomized-controlled cross-over designInternational Journal of Behavioral Nutrition and Physical Activity
Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAMMolecular Psychiatry
Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary FunctionPlos Genetics
Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in WomenPlos Genetics
Chronic non-communicable diseases: a global epidemic of the 21st centuryLaeknabladid
Coronary artery calcium distributions in older persons in the AGES-Reykjavik studyEuropean Journal of Epidemiology

2011

Effects of statin medication on mortality risk associated with type 2 diabetes in older persons: the population-based AGES-Reykjavik StudyBmj Open
Post-Genomic Update on a Classical Candidate Gene for Coronary Artery Disease: ESR1Circulation-Cardiovascular Genetics
Multiple Loci Are Associated with White Blood Cell PhenotypesPlos Genetics
Prevalence of Age-related Macular Degeneration in Old Persons: Age, Gene/Environment Susceptibility Reykjavik StudyOphthalmology
Meta-analysis of genome-wide association for migraine in six population-based European cohortsEuropean Journal of Human Genetics
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaqueNature Genetics
Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 ChildrenPlos Medicine
Improving the Prediction of Incident Atrial Fibrillation ReplyArchives of Internal Medicine
LONG-TERM EFFECTS OF A 6-MONTH MULTIMODAL TRAINING INTERVENTION ON THE RETENTION OF PHYSICAL FITNESS IN OLDER INDIVIDUALSGerontologist
Male-female differences in the association between incident hip fracture and proximal femoral strength: A finite element analysis studyBone
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressureNature Genetics
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasmaNature Genetics
Meta-Analysis of Genome-Wide Association Studies in > 80 000 Subjects Identifies Multiple Loci for C-Reactive Protein LevelsCirculation
Human metabolic individuality in biomedical and pharmaceutical researchNature
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery diseaseNature Genetics
FORCE DIRECTIONS FOR OPTIMAL PROXIMAL FEMORAL STRENGTH AND HIP FRACTURE RISK ASSESSMENT IN MEN AND WOMEN: THE AGES-REYKJAVIK STUDYOsteoporosis International
Effects of age and sex on the strength and cortical thickness of the femoral neckBone
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung functionNature Genetics
Genome-Wide Association Studies of Cerebral White Matter Lesion Burden: The CHARGE ConsortiumAnnals of Neurology
Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial InfarctionCirculation
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profileNature Genetics
Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 DiabetesDiabetes
Genetic variants in novel pathways influence blood pressure and cardiovascular disease riskNature
Brain Volume Decline Predicts Cognitive Decline: The AGES Reykjavik StudyNeurology
Atrial fibrillation is associated with brain atrophy independent of cerebral infarction: the AGES-reykjavik studyEuropean Heart Journal
Childhood Growth; a Predictor of Serum Uric Acid in Adult Age in a High Birth Weight PopulationJournal of Developmental Origins of Health and Disease
EFFECT OF OSTEOPOROTIC FRACTURES ON FUNCTION, QUALITY OF LIFE AND HOSPITALIZATION. THE AGES-REYKJAVIK STUDYGerontologist
Childhood Growth and Adult Hypertension in a Population of High Birth WeightHypertension
CUBN Is a Gene Locus for AlbuminuriaJournal of the American Society of Nephrology
A GENOME-WIDE ASSOCIATION ANALYSIS OF INSOMNIA: THE CHARGE CONSORTIUMSleep
A genome-wide association study of agingNeurobiology of Aging
A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery DiseaseCirculation-Cardiovascular Genetics
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource studyHuman Molecular Genetics
Association of Hypertension Drug Target Genes With Blood Pressure and Hypertension in 86 588 IndividualsHypertension
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant dataBritish Medical Journal
RANTES/CCL5 and Risk for Coronary Events: Results from the MONICA/KORA Augsburg Case-Cohort, Athero-Express and CARDIoGRAM StudiesPlos One
Diabetes mellitus, fasting glucose, and risk of cause-specific death.The New England journal of medicine
Validity of retrospective diet history: assessing recall of midlife diet using food frequency questionnaire in later life.The journal of nutrition, health & aging
Hand Osteoarthritis Severity is Associated with Total Knee Joint Replacements Independently of BMI. The Ages-Reykjavik Study.The open rheumatology journal
N-Terminal Pro-Brain Natriuretic Peptide Is a More Useful Predictor of Cardiovascular Disease Risk Than C-Reactive Protein in Older Men With and Without Pre-Existing Cardiovascular DiseaseJournal of the American College of Cardiology
Candidate Gene Association Study for Diabetic Retinopathy in Persons with Type 2 Diabetes: The Candidate Gene Association Resource (CARe)Investigative Ophthalmology & Visual Science
Large-scale gene-centric analysis identifies novel variants for coronary artery disease.PLoS genetics
Prevalence and Prognosis of Unrecognized Myocardial Infarction by Cardiac Magnetic Resonance versus ECG in the ICELANDMI StudyCirculation
VALIDITY OF RETROSPECTIVE DIET HISTORY: ASSESSING RECALL OF MIDLIFE DIET USING FOOD FREQUENCY QUESTIONNAIRE IN LATER LIFEJournal of Nutrition Health & Aging
Giant Cell Arteritis Is Associated with Incident Coronary Heart Disease-A Population-Based Study.Arthritis and Rheumatism
Giant Cell Arteritis Is Associated with An Increase in Both All-Cause and Cardiovascular MortalityArthritis and Rheumatism
Trends in the incidence and prevalence of atrial fibrillation in Iceland and future projectionsEuropace
Associations of Visceral and Liver Fat With the Metabolic Syndrome Across the Spectrum of Obesity: The AGES-Reykjavik StudyObesity
Diabetes Mellitus, Fasting Glucose, and Risk of Cause-Specific DeathNew England Journal of Medicine
Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic TraitsPlos Genetics
Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility - Reykjavik StudyBrain
Distribution of cortical bone in the femoral neck and hip fracture: A prospective case-control analysis of 143 incident hip fractures; the AGES-REYKJAVIK StudyBone
Substantial Variation in qPCR Measured Mean Blood Telomere Lengths in Young Men from Eleven European CountriesAmerican Journal of Human Biology
Women's fish and fish oil intake in adolescence and midlife and coronary heart disease riskAnnals of Nutrition and Metabolism
THE JOINT EFFECT OF PHYSICAL ACTIVITY AND BODY MASS INDEX AT MID-LIFE ON COGNITIVE FUNCTION IN LATE LIFE: AGE GENE/ENVIRONMENT SUSCEPTIBILITY - REYKJAVIK STUDYGerontologist
The presence of total knee or hip replacements due to osteoarthritis enhances the positive association between hand osteoarthritis and atherosclerosis in women: the AGES-Reykjavik studyAnnals of the Rheumatic Diseases

2010

Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass Index (vol 3, 65er1, 2011)Science Translational Medicine
Genome-wide Analysis of Genetic Loci Associated With Alzheimer DiseaseJama-Journal of the American Medical Association
Markers of Dysglycaemia and Risk of Coronary Heart Disease in People without Diabetes: Reykjavik Prospective Study and Systematic ReviewPlos Medicine
Chronic kidney disease and risk of major cardiovascular disease and non-vascular mortality: prospective population based cohort studyBritish Medical Journal
Hundreds of variants clustered in genomic loci and biological pathways affect human heightNature
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.Lancet (London, England)
Current and projected prevalence estimates of atrial fibrillation in a northern european populationEuropean Heart Journal
Biological, clinical and population relevance of 95 loci for blood lipidsNature
Correlation of Echocardiographic Findings With Cerebral Infarction in Elderly Adults The AGES-Reykjavik StudyStroke
Genome-wide association study of PR intervalNature Genetics
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distributionNature Genetics
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.Lancet (London, England)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass indexNature Genetics
Effect of rheumatoid factor on mortality and coronary heart diseaseAnnals of the Rheumatic Diseases
Magnetization transfer imaging, white matter hyperintensities, brain atrophy and slower gait in older men and womenNeurobiology of Aging
Cerebral microbleeds, retinopathy, and dementia The AGES-Reykjavik StudyNeurology
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conductionNature Genetics
A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology ConsortiumJournals of Gerontology Series a-Biological Sciences and Medical Sciences
Analysing the Large Decline in Coronary Heart Disease Mortality in the Icelandic Population Aged 25-74 between the Years 1981 and 2006Plos One
Common variants in KCNN3 are associated with lone atrial fibrillationNature Genetics
An Assessment of Genetic Effects on Body Weight Change during AdulthoodCardiology
THE PRESENCE OF TOTAL KNEE OR HIP REPLACEMENTS DUE TO OA STRENGTHENS THE POSITIVE ASSOCIATION BETWEEN HAND OA AND ATHEROSCLEROSIS IN FEMALES: THE AGES-REYKJAVIK STUDYOsteoarthritis and Cartilage
TYPE 3 FINGER LENGTH PATTERN IS ASSOCIATED WITH TOTAL KNEE (TKR) BUT NOT WITH HIP REPLACEMENTS (THR) IN THE ELDERLY: THE AGES-REYKJAVIK STUDYOsteoarthritis and Cartilage
Tissue plasminogen activator, fibrin D-dimer and Von Willebrand factor antigens and risk of future coronary heart diseaseJournal of Thrombosis and Haemostasis
Validation of an Atrial Fibrillation Risk Algorithm in Whites and African AmericansArchives of Internal Medicine
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studiesNature Genetics
PROXIMAL FEMORAL STRENGTH FOR PREDICTING HIP FRACTURE IN MEN AND WOMEN: THE AGES-REYKJAVIK STUDYOsteoporosis International
RECLASSIFICIATION OF 10 YEAR CHD RISK COMPARED BY PRESENCE OF CAROTID PLAQUE AND HIGH CRPAtherosclerosis Supplements
RED CELL DISTRIBUTION WIDTH AND BRAIN TISSUE VOLUMES, CEREBRAL INFARCTS, AND COGNITIVE FUNCTIONGerontologist
PHOTOGRAPHIC SCORING IS INSENSITIVE FOR MONITORING PROGRESS OF HAND OSTEOARTHRITIS, BUT SIDE BY SIDE COMPARISON OF PHOTOGRAPHS DETECTS PROGRESS AT 5 YEAR INTERVALS IN THE ELDERLY. THE AGES-REYKJAVIK STUDYOsteoarthritis and Cartilage
THE ASSOCIATION BETWEEN MIDLIFE BODY MASS INDEX AND BRAIN VOLUME IN LATE LIFE: AGE GENE/ENVIRONMENT SUSCEPTIBILITY - REYKJAVIK STUDYGerontologist
Separating the Mechanism-Based and Off-Target Actions of Cholesteryl Ester Transfer Protein Inhibitors With CETP Gene PolymorphismsCirculation
Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studiesInternational Journal of Epidemiology
New loci associated with kidney function and chronic kidney diseaseNature Genetics
Load of Myocardial Infarction and Risk of Brain Infarction: The AGES-Reykjavik StudyNeurology
JOINT ASSOCIATION OF VISCERAL AND THIGH SUBCUTANEOUS FAT WITH THE METABOLIC SYNDROME: THE AGES-REYKJAVIK STUDYGerontologist
NT-proBNP is associated with coronary heart disease risk in healthy older women but fails to enhance prediction beyond established risk factors: Results from the British Women's Heart and Health StudyAtherosclerosis
IGF2BP1, IGF2BP2 and IGF2BP3 genotype, haplotype and genetic model studies in metabolic syndrome traits and diabetesGrowth Hormone & Igf Research
Migraine with aura and risk of cardiovascular and all cause mortality in men and women: prospective cohort studyBritish Medical Journal
Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation In VivoPlos Genetics
Genome-wide association analysis identifies multiple loci related to resting heart rateHuman Molecular Genetics
Genome-Wide Association Studies of MRI-Defined Brain Infarcts Meta-Analysis From the CHARGE ConsortiumStroke
Genome-Wide Association Studies of Serum Magnesium, Potassium, and Sodium Concentrations Identify Six Loci Influencing Serum Magnesium LevelsPlos Genetics
Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk FactorsCirculation-Cardiovascular Genetics
Myocardial structure and function by echocardiography in relation to glucometabolic status in elderly subjects from 2 population-based cohorts: A cross-sectional studyAmerican Heart Journal
Persistent Chlamydia Pneumoniae serology is related to decline in lung function in women but not in men. Effect of persistent Chlamydia pneumoniae infection on lung function.BMC pulmonary medicine
Coronary Artery Calcium, Brain Function and Structure The AGES-Reykjavik StudyStroke
GENOME-WIDE ASSOCIATION ANALYSIS IDENTIFIES VARIANTS ASSOCIATED WITH NONALCOHOLIC FATTY LIVER DISEASE THAT HAVE DISTINCT EFFECTS ON SERUM LIPIDSHepatology
Genome-Wide Association Studies of MRI-Defined Brain Infarcts: Meta-Analysis from the CHARGE ConsortiumNeurology
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studiesLancet
THE ASSOCIATION BETWEEN MIDLIFE BODY MASS INDEX AND COGNITIVE FUNCTION IN LATE LIFE: AGE GENE/ENVIRONMENT SUSCEPTIBILITY - REYKJAVIK STUDYGerontologist
Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass IndexScience Translational Medicine
Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKDJournal of the American Society of Nephrology
The Effect of Midlife Physical Activity on Cognitive Function Among Older Adults: AGES-Reykjavik StudyJournals of Gerontology Series a-Biological Sciences and Medical Sciences
Sequence variation in the LDL receptor gene, and its effect on plasma lipid levels.
Common variants in the calcium-sensing receptor gene are associated with total serum calcium levelsHuman Molecular Genetics

2009

Relative Risk Is a Better Discriminator Than Absolute Risk When Estimating Ten-Year Risk of Coronary Heart Disease in Young AdultsJournal of the American College of Cardiology
Trends in body weight and diabetes in forty years in IcelandLaeknabladid
Meta-analysis of genome-wide association data identifies two loci influencing age at menarcheNature Genetics
Lifelong physical activity and bone health in elderly men and women: AGES-Reykjavik StudyJournal of the American Geriatrics Society
Genome-wide association meta-analysis for total serum bilirubin levelsHuman Molecular Genetics
Migraine Symptoms in Middle-Age Predict Brain Infarcts in Late-Life: A 25-Year Longitudinal Population-Based MRI StudyNeurology
Migraine Headache in Middle Age and Late-Life Brain Infarcts EDITORIAL COMMENTObstetrical & Gynecological Survey
Migraine, headache and survival in the Reykjavik studyCephalalgia
Microvascular Lesions in the Brain and Retina: The Age, Gene/Environment Susceptibility-Reykjavik StudyAnnals of Neurology
Association of Left Ventricular Concentric Hypertrophy and Thoracic Aortic Calcification With Cardiac Morbidity and Mortality in Elderly Subjects in the ICELAND-MI Substudy of AGES-ReykjavikCirculation
Thoracic aortic calcification in the elderlyCardiology
Migraine Headache in Middle Age and Late-Life Brain InfarctsJama-Journal of the American Medical Association
Comparative Efficacy of Strategies for Risk Screening and Prevention for Cardiovascular DiseaseJournal of the American College of Cardiology
Multiple loci associated with indices of renal function and chronic kidney diseaseNature Genetics
[Trends in body weight and diabetes in forty years in Iceland].Laeknabladid
Migraine headache in middle age and late-life brain infarcts.JAMA
Lipoprotein(a) concentration and the risk of coronary heart disease, stroke, and nonvascular mortality.JAMA
Explaining the massive declines in coronary heart disease mortality rates in Iceland, 1981-2006Cardiology
Genetic influences on economic behaviorBehavior Genetics
Genome-wide Association Analysis of 25,330 Individuals Identifies Multiple Loci Associated With Resting Heart RateCirculation
Common Variants in KCNN3 Are Associated With Early-Onset Atrial FibrillationCirculation
C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis.Lancet (London, England)
High hand joint mobility is associated with radiological CMC1 osteoarthritis: the AGES-Reykjavik studyOsteoarthritis and Cartilage
Glycemic Status and Brain Injury in Older Individuals The Age Gene/Environment Susceptibility-Reykjavik StudyDiabetes Care
Hand osteoarthritis in older women is associated with carotid and coronary atherosclerosis: the AGES Reykjavik studyAnnals of the Rheumatic Diseases
Genome-wide association study of blood pressure and hypertensionNature Genetics
CEREBRAL MICROBLEEDS AND CARDIOVASCULAR RISK FACTORS: THE AGES REYKJAVIK STUDYJournal of Neurology Neurosurgery and Psychiatry
Multiple loci influence erythrocyte phenotypes in the CHARGE ConsortiumNature Genetics
NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE ConsortiumPlos Genetics
The interaction of adiposity with the CRP gene affects CRP levels: Age, Gene/Environment Susceptibilty-Reykjavik StudyInternational Journal of Obesity
THE ASSOCIATION BETWEEN MIDLIFE PHYSICAL ACTIVITY AND DEPRESSIVE SYMPTOMS IN LATE LIFE: AGE GENE/ENVIRONMENT SUSCEPTIBILITY - REYKJAVIK STUDYGerontologist
CAROTID PLAQUE AND IMT IN THE POPULATION BASED REFINE REYKJAVIK STUDY IN CONTEXT WITH THE SHAPE GUIDELINESAtherosclerosis Supplements
Why Have Coronary Heart Disease Mortality Rates in Iceland Plummeted Between 1981 and 2006?Circulation
Ventricular Dilation Association With Gait and CognitionAnnals of Neurology
Changes in life expectancy of people with type 2 diabetes relative to non-diabetics over the last 40 years, from Reykjavik-AGES StudyDiabetologia
Major lipids, apolipoproteins, and risk of vascular disease.JAMA
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestryNature Genetics
Potential association of the localisation of myocardial infarction detected by magnetic resonance imaging, and the quantification of calcium in the coronary arteries detected with computed tomography and calcium scoring softwareCardiology
Prevalence of unrecognized and recognized myocardial infarction in older individuals with elevated NT proBNPCardiology
Overweight and Obesity Modify the Association of Visceral and Liver Fat with the Metabolic Syndrome in the Age, Gene/Environment Susceptibility (AGES)-Reykjavik StudyCirculation
Aortic Valve Calcium Scores Are Strong Predictors of Aortic Stenosis in a Population-Based Setting: The AGES-Reykjavik StudyCirculation
C-reactive protein in migraine sufferers similar to that of non-migraineurs: the Reykjavik StudyCephalalgia
Cerebral Infarcts and Cognitive Performance Importance of Location and Number of InfarctsStroke
B-Type Natriuretic Peptides and Cardiovascular Risk Systematic Review and Meta-Analysis of 40 Prospective StudiesCirculation
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Design of Prospective Meta-Analyses of Genome-Wide Association Studies From 5 CohortsCirculation-Cardiovascular Genetics
Lipoprotein(a): a causal independent risk factor for coronary heart disease?Current Opinion in Cardiology
Association of Hypertension Drug Target Genes With Blood Pressure and Hypertension: Results From a Genome-wide Association Study in 29,136 IndividualsCirculation
Unfavourable risk factors for type 2 diabetes mellitus are already apparent more than a decade before onset in a population-based study of older persons: from the Age, Gene/Environment Susceptibility-Reykjavik Study (AGES-Reykjavik)European Journal of Epidemiology
Abnormal T-wave axis is associated with coronary artery calcification in older adultsScandinavian Cardiovascular Journal
Lipid lowering medication attributes little to the changes in total cholesterol in the Icelandic populationCardiology

2008

Cerebral microbleeds in the population based AGES-Reykjavik study: prevalence and locationJournal of Neurology Neurosurgery and Psychiatry
Prognostic Value of Myocardial Infarction and Left Ventricular Ejection Fraction In Elderly Subjects: Insights from the ICELAND-MI Substudy of AGES-ReykjavikCirculation
The association of telomere length with paternal history of premature myocardial infarction in the European Atherosclerosis Research Study IIJournal of Molecular Medicine-Jmm
Localized measures of callosal atrophy are associated with late-life hypertension in a population-based study: Age gene/environment susceptibility-Reykjavik studyNeurology
EQUIVALENCE OF SUBCLINICAL ATHEROSCLEROSIS MEASUREMENTS TO CARDIVASCULAR DEATH FOR EVALUATING RISK FACTOR IMPACT. THE REFINE REYKJAVIK STUDYAtherosclerosis Supplements
Hemodynamics of increased pulse pressure in older women in the community-based age, Gene/Environment susceptibility-reykjavik studyHypertension
Lipoprotein(a) levels and risk of future coronary heart diseaseArchives of Internal Medicine
Long-term interleukin-6 levels and subsequent risk of coronary heart disease: Two new prospective studies and a systematic reviewPlos Medicine
CARDIO-ANKLE VASCULAR INDEX, AN INDEPENDENT RISK FACTOR FOR ATHEROSCLEROSIS BUT DOES NOT IMPROVE PREDICTABILITY. THE POPULATIONS BASED REFINE REYKJAVIK STUDYAtherosclerosis Supplements
Birth weight and risk of type 2 diabetes: a systematic review.JAMA
White matter lesions and cognitive performance: the role of cognitively complex leisure activity.The journals of gerontology. Series A, Biological sciences and medical sciences
Birth Weight and Risk of Type 2 Diabetes A Systematic ReviewJama-Journal of the American Medical Association
Use of Genetic Markers in Prediction of FracturesJournal of Bone and Mineral Research
[Foot disease in Icelandic patients with established type 2 diabetes].Laeknabladid
A Composite Bone Score with QCT Bone Measurements and Fracture History.Journal of Bone and Mineral Research
Retinal and cerebral microvascular signs and diabetes - The age, Gene/Environment Susceptibility-Reykjavik StudyDiabetes
Prediction of Incidental Low Trauma Limb Fractures in Older Men and Women with Quantitative CT(QCT) Variables of Bone and Muscles in Mid-Thigh: The AGES-Reykjavik StudyJournal of Bone and Mineral Research
Intra-individual change over time in DNA methylation with familial clusteringJama-Journal of the American Medical Association
Cognitive Impairment: An Increasingly Important Complication of Type 2 DiabetesAmerican Journal of Epidemiology
Early discharge and home intervention reduces unit costs after total hip replacement: results of a cost analysis in a randomized studyInternational Journal of Health Care Finance & Economics
Localized measures of callosal atrophy are associated with late-life hypertension: AGES-Reykjavik StudyNeuroimage
Foot disease in Icelandic patients with established type 2 diabetesLaeknabladid
Changes In Total Cholesterol Levels In The Icelandic Population Is Not Attributable To Lipid Lowering Medication UseCirculation
C-REACTIVE PROTEIN (CRP) POLYMORPHISM MODIFIES THE ASSOCIATION OF ADIPOSITY AND CRP LEVELS: AGE GENE/ENVIRONMENT SUSCEPTIBILITY - REYKJAVIK STUDYAtherosclerosis Supplements
Prevalence of Unrecognized and Recognized Myocardial Infarction in Older Individuals with Elevated NT-pro-BNPCirculation
THE EFFECT OF MIDLIFE PHYSICAL ACTIVITY ON PHYSICAL PERFORMANCE AMONG OLDER ADULTS: AGES -REYKJAVIK STUDYGerontologist
Proximal Femoral Fragility and Age-Related White Matter Lesions by Brain MRI in Elderly Subjects: the Age Gene/Environment Susceptibility Study-ReykjavikJournal of Bone and Mineral Research
Pattern and prevalence of herbal and dietary supplements in an elderly cohort: AGES-Reykjavik studyPharmacoepidemiology and Drug Safety
Prevalence of age-related macular degeneration in the ages - Reykjavik studyActa Ophthalmologica
White matter lesions and cognitive performance: The role of cognitively complex leisure activityJournals of Gerontology Series a-Biological Sciences and Medical Sciences

2007

Inaccuracy in self-report of fractures may underestimate association with health outcomes when compared with medical record based fracture registryEuropean Journal of Epidemiology
C-reactive protein levels in migraine patients is similar to that of controlsCephalalgia
Magnetization transfer ratio and cognitive function in the general populationNeurology
Increasing glucose levels and BMI predict future heart failure Experience from the Reykjavik StudyEuropean Journal of Heart Failure
Gender comparison in muscle-bone relationship in mid-thigh in old ageBone
Estimation of 10-year risk of fatal cardiovascular disease and coronary heart disease in Iceland with results comparable with those of the Systematic Coronary Risk Evaluation projectEuropean Journal of Cardiovascular Prevention & Rehabilitation
Optimum expression of adult lung function based on all-cause mortality: Results from the Reykjavik studyRespiratory Medicine
Renal function and risk of coronary heart disease in general populations: New prospective study and systematic reviewPlos Medicine
Triglycerides and the risk of coronary heart disease - 10 158 incident cases among 262 525 participants in 29 Western prospective studiesCirculation
Bone mineral density in hip and spine by quantitative CT and previous history as predictors of incidental low trauma fractures in elderly men and womenJournal of Bone and Mineral Research
Nordic biological specimen banks as basis for studies of cancer causes and control - more than 2 million sample donors, 25 million person years and 100 000 prospective cancersActa Oncologica
Protein expression within the human renal cortex and renal cell carcinoma: the implication of cold ischemiaCell Preservation Technology
Migraine in mid-life predicts brain Infarcts in old age: A longitudinal population-based MRI studyAnnals of Neurology
Age, Gene/Environment Susceptibility-Reykjavik Study: Multidisciplinary applied phenomicsAmerican Journal of Epidemiology
Circulating concentrations of insulin markers and coronary heart disease: a quantitative review of 19 Western prospective studiesEuropean Heart Journal
T-wave axis is associated with coronary artery calcium score in an asymptomatic elderly populationCirculation
Monoclonal gammopathy: natural history studied with a retrospective approachHaematologica-the Hematology Journal
Population-based register of acute myocardial infarction: manual of operations.European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology
Estimation of 10-year risk of fatal cardiovascular disease and coronary heart disease in Iceland with results comparable with those of the Systematic Coronary Risk Evaluation project.European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology
[The relationship between QRS voltage on ECG (the Minnesota code) and cardiac mortality amongst males. The Reykjavik Study].Laeknabladid
The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases.European journal of epidemiology
A variant in CDKAL1 influences insulin response and risk of type 2 diabetesNature Genetics
[Prevalence of type 2 diabetes mellitus in Iceland 1967-2002].Laeknabladid
Population-based register of acute myocardial infarction: manual of operationsEuropean Journal of Cardiovascular Prevention & Rehabilitation
Infant feeding patterns and midlife erythrocyte sedimentation rateActa Paediatrica
The relationship between QRS voltage on ECG and cardiac mortality amongst malesInternational Journal of Cardiology
Myocardial function and structure by echocardiography/Doppler and tissue Doppler in pre-diabetic and diabetic elderly subjects in two population-based cohortsEuropean Heart Journal

2006

A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarctionNature Genetics
[The health risk associated with smoking has been seriously underestimated. The Reykjavik Study].Laeknabladid
Increased cardiovascular risk among children of women with hypertensive disorders of pregnancy.Hypertension in Pregnancy
Risk assessment for cardiovascular death among old people in comparison to young people - The Reykjavik studyAtherosclerosis Supplements
Examination of genetic effects of polymorphisms in the MCP-1 and CCR2 genes on MI in the Icelandic populationAtherosclerosis
The relation between aortic distensibility and calcified aortic atherosclerosis: Cardiovascular MRI and CT correlationsJournal of the American College of Cardiology
Type 2 diabetes and cerebral white matter lesions association in the AGES-Reykjavik StudyDiabetes
Gender differences in metabolic features of type 2 diabetes in the AGES-Reykjavik StudyDiabetologia
Prevalence of recognized and unrecognized myocardial infarction: The ICELAND MI substudy to the AGES-Reykjavik studyJournal of the American College of Cardiology
Increasing sex difference in bone strength in old age: The Age, Gene/Environment Susceptibility-Reykjavik study (AGES-REYKJAVIK)Bone
Diabetes and cognitive performance: The age gene environment susceptibility Reykjavik study (AGES-R)Diabetes
Echocardiographic associations of prevalent stroke in an elderly cohort: the Age/Gene environmental susceptibility Reykjavik study (AGES-Reykjavik)Circulation
Apolipoprotein E genotype and statins affect CRP levels through independent and different mechanisms: AGES-Reykjavik StudyAtherosclerosis
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetesNature Genetics

2005

Apolipoprotein E genotype and statin use associated with C-reactive protein levels irrespective of coronary event: The AGES-Reykjavik StudyCirculation
Socio-demographic characteristics of phenotypes of cognitive reserve in a population sample: The ages studyGerontologist
The prevalence of infarct and non-infarct as the etiology in impaired left ventricular systolic function in the elderly: A gadolinium enhanced cardiac MRI studyCirculation
Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced riskJournal of Experimental Medicine
The gender difference in bone strength continues to increase into old ageBone
[Latent autoimmune diabetes in adults in Iceland: prevalence, phenotype and relatedness].Laeknabladid
[Trends in overweight and obesity in 45-64 year old men and women in Reykjavík 1975-1994. 2001].Laeknabladid
The gene encoding phosphodiesterase 4D confers risk of ischemic stroke (vol 35, pg 131, 2003)Nature Genetics
The accuracy of self-report of fractures in older people; A comparison of questionnaire and fracture registry in the AGES Reykjavik studyJournal of Bone and Mineral Research
Short hospital stay augmented with education and home-based rehabilitation improves function and quality of life after hip replacement - Randomized study of 50 patients with 6 months of follow-upActa Orthopaedica
Prevalence of cerebral microbleeds in the AGES Reykjavik StudyNeurology
How well do subclinical atherosclerosis imaging measurements correlate with prior coronary event in old age the ages. Reykjavik StudyAtherosclerosis Supplements
Estimation of ten year risk of fatal cardiovascular disease in Iceland: a comparison with the SCORE projectEuropean Heart Journal
Glucose abnormalities and heart failure predict poor prognosis in the population-based Reykjavik StudyEuropean Journal of Cardiovascular Prevention & Rehabilitation
Prevalence of chronic kidney disease based on estimated glomerular filtration rate and proteinuria in Icelandic adultsNephrology Dialysis Transplantation
Association between vascular calcification and cerebral white matter lesions in a population based cohort: Age, Gene/Environment Susceptibility (AGES) Reykjavik StudyCirculation
Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment - Individual patient meta-analysis of 13,677 subjectsCirculation
The association between glucose abnormalities and heart failure in the population-based Reykjavik studyDiabetes Care
Serum uric acid and coronary heart disease in 9,458 incident cases and 155,084 controls: Prospective study and meta-analysisPlos Medicine
A gene encoding the Kv channel interacting protein 1 (KChIP1) confers risk of type 2 diabetes mellitusDiabetes
Prevalence of type 2 diabetes mellitus and the metabolic syndrome in Iceland 1967-2002Diabetologia
Associations of vascular calcification and bone mineral from quantitative computerized tomography of the spine are explained by age and other risk factors: The Age, Gene/Evironment Susceptibility Reykjavik StudyCirculation
Coronary and aortic calcium increase differently with age in those with and without history of coronary event (myocardial infarction, PCI and CABG): The AGES-Reykjavik StudyCirculation
The relation between disturbed glucose regulation and heart failure - experiences from the Reykjavik StudyEuropean Heart Journal

2004

Defined overweight and obesity in youth and adulthood in the last centuryInternational Journal of Obesity
Loss of teeth and coronary heart disease.The International journal of prosthodontics
Association between size at birth, truncal fat and obesity in adult life and its contribution to blood pressure and coronary heart disease; study in a high birth weight populationEuropean Journal of Clinical Nutrition
Ages Reykjavik Study: Future phenotypes of neurodegenerationNeurobiology of Aging
The age-related increase in bone area assessed by QCT is site- but not sex-specific: Age, Gene/Environment Susceptibility-Reykjavik Study.Journal of Bone and Mineral Research
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and strokeNature Genetics
Loss of teeth and coronary heart diseaseInternational Journal of Prosthodontics
Prevalence and phenotype of LADA in Icelandic Type 2 diabeticsDiabetologia
Genetic polymorpisms in MCP-1 or CCR2 and coronary artery diseaseAtherosclerosis Supplements
The absolute risk of recurrent myocardial infarction is similar amongst both sexes: MONICA Iceland Study 1981-1999European Journal of Cardiovascular Prevention & Rehabilitation
Familial risk of lung carcinoma in the Icelandic populationJama-Journal of the American Medical Association
C-reactive protein and coronary heart disease - ReplyNew England Journal of Medicine
Glucose abnormalities and heart failure - a dangerous combination. Results from the Reykjavik studyEuropean Heart Journal
Midlife cardiovascular risk factors predict coronary calcium in older men and women, whereas concurrently measured risk factors do not: the AGES Reykjavik studyCirculation
C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart diseaseNew England Journal of Medicine

2003

The gene encoding phosphodiesterase 4D confers risk of ischemic strokeNature Genetics
Subclinical intestinal inflammation: An inherited abnormality in Crohn's disease relatives?Gastroenterology
Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2American Journal of Human Genetics
A genome wide scan for hypertriglyceridemia loci in a large Icelandic cohort maps a gene to chromosome 10p.American Journal of Human Genetics
A linkage study in heavy smokers suggests the presence of both causative and protective genes for chronic obstructive pulmonary disease (COPD).American Journal of Human Genetics
Estimation of chronic kidney disease in the Icelandic populationJournal of the American Society of Nephrology
[Changes in smoking habits in the last thirty years in middle-aged Icelanders and their causes - Results from population surveys of the Icelandic Heart Association.].Laeknabladid
Risk of cardiovascular events in young males in Iceland: A prospective studyAtherosclerosis Supplements
The GSTT null allele enhances the risk of smoking for developing myocardial infarction in Icelandic women: The Reykjavik StudyAtherosclerosis Supplements
[The use of herbal medicines, food supplements, and OTCs - design and testing of a questionnaire.].Laeknabladid
Systematic family screening for familial hypercholesterolemia in IcelandArteriosclerosis Thrombosis and Vascular Biology
The effect of smoking on the formation and fate of immune comlexesMolecular Immunology
High birth weight does not guarantee protection from type 2 diabetes - Reply to ND Willows and K Gray-DonaldAmerican Journal of Clinical Nutrition
Erythrocyte sedimentation rate, an independent predictor of coronary heart disease in men and women - The Reykjavik studyAmerican Journal of Epidemiology

2002

Fifteen percent of myocardial infarctions and coronary revascularizations explained by family history unrelated to conventional risk factors - The Reykjavik Cohort StudyEuropean Heart Journal
Do lipids, blood pressure, diabetes, and smoking confer equal risk of myocardial infarction in women as in men? The Reykjavik StudyJournal of Cardiovascular Risk
Do lipids, blood pressure, diabetes, and smoking confer equal risk of myocardial infarction in women as in men? The Reykjavik Study.Journal of cardiovascular risk
Isolation of a gene for common forms of stroke.American Journal of Human Genetics
Screening for diabetes combining geneological information and fasting glucose identities individuals at adverse cardiovascular riskDiabetologia
Size at birth and coronary artery disease in a population with high birth weightAmerican Journal of Clinical Nutrition
Size at birth and glucose intolerance in a relatively genetically homogeneous, high-birth weight populationAmerican Journal of Clinical Nutrition
Prevalence of peripheral neuropathy symptoms and signs in established Type 2 diabetes in IcelandDiabetologia
Size at birth and glucose intolerance in a relatively genetically homogeneous, high-birth weight population.The American journal of clinical nutrition
Size at birth and coronary artery disease in a population with high birth weight.The American journal of clinical nutrition
Localization of a gene for peripheral arterial occlusive disease to chromosome 1p31American Journal of Human Genetics
Fifteen percent of myocardial infarctions and coronary revascularizations explained by family history unrelated to conventional risk factors. The Reykjavik Cohort Study.European heart journal
Declining coronary heart disease mortality in Iceland: Contribution by incidence, recurrence and case fatality rateScandinavian Cardiovascular Journal
Localization of a susceptibility gene for common forms of stroke to 5q12American Journal of Human Genetics
Relationship between size at birth and hypertension in a genetically homogenous population of high birth weightJournal of Hypertension

2001

Gene-environment and gene-gene interaction in the determination at plasma homocysteine levels in healthy middle-aged menThrombosis and Haemostasis
The effect of the C677T and A1298C polymorphisms in the methylenetetrahydrofolate reductase gene on homocysteine levels in elderly men and women from the British regional heart studyAtherosclerosis
Gene-environment and gene-gene interaction in the determination of plasma homocysteine levels in healthy middle-aged men.Thrombosis and haemostasis
[Trends in overweight and obesity in 45-64 year old men and women in Reykjavik 1975-1994.].Laeknabladid
[Homocysteine, folate and cobalamin in Icelandic men and women.].Laeknabladid
[Familial hypercholesterolemia in Iceland. Review and outcome of family screening.].Laeknabladid
Variations in the CAPN10 gene associate with non-insulin dependent diabetes in Icelanders.American Journal of Human Genetics
The -629C > A polymorphism in the CETP gene does not explain the association of TaqIB polymorphism with risk and age of myocardial infarction in Icelandic menAtherosclerosis
[Changes in myocardial infarction incidence and mortality in Iceland.].Laeknabladid

2000

Variants in the cholesterol ester transfer protein and lipoprotein lipase genes are predictors of plasma cholesterol response to dietary changeAtherosclerosis
A genome wide search for genetic risk factors in Icelandic stroke patients.American Journal of Human Genetics
Treatment with different doses of folic acid in haemodialysis patients: effects on folate distribution and aminothiol concentrationsNephrology Dialysis Transplantation

1999

The effect of C677T and C1298A polymorphisms in methylenetetrahydrofolate reductase on plasma homocysteine levels in elderly men and women from the British Regional Heart StudyAtherosclerosis
The effect of a common polymorphism in the cholesteryl ester transfer protein gene on plasma HDL concentration and the risk of myocardial infarction in the homogenous Icelandic populationAtherosclerosis
Cholesteryl ester transfer protein gene effect on CETP activity and plasma high-density lipoprotein in European populationsEuropean Journal of Clinical Investigation
Cholesterol ester transfer protein genotype is a determinant of variation in plasma cholesterol response to change in dietary fat intakeAtherosclerosis
Hyperhomocysteinaemia, genetics and cardiovascular disease riskEuropean Heart Journal
Effect of the Asp9 to Asn polymorphism in lipoprotein lipase on plasma lipid levels and the risk of developing MI in the homogenous Icelandic populationAtherosclerosis
The type of mutation in the low density lipoprotein receptor gene influences the cholesterol-lowering response of the HMG-CoA reductase inhibitor simvastatin in patients with heterozygous familial hypercholesterolaemiaAtherosclerosis
Predictive value of plasma cholesterol for total and cardiovascular mortality and myocardial infarction depending on age in the Reykjavik studyAtherosclerosis
Hyperhomocysteinaemia, genetics and cardiovascular disease risk.European heart journal

1998

Linkage disequilibrium at the cystathionine beta synthase (CBS) locus and the association between genetic variation at the CBS locus and plasma levels of homocysteineAnnals of Human Genetics
C677T (thermolabile alanine/valine) polymorphism in methylenetetrahydrofolate reductase (MTHFR): its frequency and impact on plasma homocysteine concentration in different European populationsAtherosclerosis
Detection of the low density lipoprotein receptor gene PvuII intron 15 polymorphism using the polymerase chain reaction: Association with plasma lipid traits in healthy men and womenDisease Markers
Linkage disequilibrium at the cystathionine beta synthase (CBS) locus and the association between genetic variation at the CBS locus and plasma levels of homocysteine. The Ears II Group. European Atherosclerosis Research Study.Annals of human genetics
Detection of the low density lipoprotein receptor gene PvuII intron 15 polymorphism using the polymerase chain reaction: association with plasma lipid traits in healthy men and women.Disease markers

1997

Interaction of the cholesteryl ester transfer protein I405V polymorphism with alcohol consumption in smoking and non-smoking healthy men, and the effect on plasma HDL cholesterol and apoAI concentrationClinical Genetics
Effect of Taq1b and I405V polymorphisms in the cholesteryl ester transfer protein (CETP) on plasma level of HDL and apoAI and postprandial triglyceride level.Atherosclerosis
The thermolabile alanine/valine polymorphism in methylenetetrahydrofolate reductase (MTHFR); its frequency and impact on plasma homocysteine concentration in different European populationsAtherosclerosis
Is there an effect of defined molecular defect on therapeutic response to HMG Co A reductase inhibitors in patients with familial hypercholesterolaemia?Atherosclerosis
Variation at the lipoprotein lipase and apolipoprotein AI-CIII gene loci are associated with fasting lipid and lipoprotein traits in a population sample from Iceland: Interaction between genotype, gender, and smoking statusGenetic Epidemiology
Single-strand conformation polymorphism analysis with high throughput modifications, and its use in mutation detection in familial hypercholesterolemiaClinical Chemistry
Interaction of the I405V polymorphism in the CETP gene with alcohol consumption in smoking and non-smoking healthy men, and the effect on plasma HDL and apoAI concentration.Atherosclerosis
Phenotypic variation in familial hypercholesterolaemia in IcelandAtherosclerosis
Spectrum of LDL receptor gene mutations in heterozygous familial hypercholesterolemia.Human mutation
Single-strand conformation polymorphism analysis with high throughput modifications, and its use in mutation detection in familial hypercholesterolemia. The IFCC Scientific Division: Committee on Molecular Biology Techniques.Journal of the International Federation of Clinical Chemistry
Additive effect of the 1405V and the Taq1B polymorphisms in the cholesteryl ester transfer protein gene on plasma HDL and apoAI concentration.Atherosclerosis
Common founder mutation in the LDL receptor gene causing familial hypercholesterolaemia in the Icelandic populationHuman Mutation
Interaction of the cholesteryl ester transfer protein I405V polymorphism with alcohol consumption in smoking and non-smoking healthy men, and the effect on plasma HDL cholesterol and apoAI concentration.Clinical genetics
The usefulness of three biallelic restriction fragment length polymorphisms versus a polymorphic dinucleotide tandem repeat polymorphism at the low-density-lipoprotein receptor gene locus for diagnosis of familial hypercholesterolemia.Disease markers
Single-strand conformation polymorphism analysis with high throughput modifications, and its use in mutation detection in familial hypercholesterolemia. International Federation of Clinical Chemistry Scientific Division: Committee on Molecular Biology Techniques.Clinical chemistry

1996

Use of the single strand conformation polymorphism method for rapid screening for mutations in the low density lipoprotein receptor gene in patients with familial hypercholesterolemia: effect on plasma lipid levels of different classes of mutations.Zeitschrift fur Gastroenterologie
High throughput modifications of single-strand conformation polymorphism analysis : mutation detection in familial hypercholesterolemia.Methods in molecular medicine

1995

THE IMPACT OF MUTATIONS IN REPEAT-5 OF THE LIGAND-BINDING DOMAIN OF THE LDL RECEPTOR ON THE CLINICAL PHENOTYPE OF FAMILIAL HYPERCHOLESTEROLEMIA (FH)Journal of Medical Genetics
Response to drugs and diet in a compound heterozygote for familial hypercholesterolaemiaArchives of Disease in Childhood
EFFECT OF THE STUI POLYMORPHISM IN THE LDL RECEPTOR GENE (ALA-370 TO THR) ON LIPID-LEVELS IN HEALTHY-INDIVIDUALSClinical Genetics
Response to drugs and diet in a compound heterozygote for familial hypercholesterolaemia.Archives of disease in childhood
UTILITIES FOR HIGH-THROUGHPUT USE OF THE SINGLE-STRAND CONFORMATIONAL POLYMORPHISM METHOD - SCREENING OF 791 PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA FOR MUTATIONS IN EXON-3 OF THE LOW-DENSITY-LIPOPROTEIN RECEPTOR GENEJournal of Medical Genetics
DRIED TEMPLATE DNA, DRIED PCR OLIGONUCLEOTIDES AND MAILING IN 96-WELL PLATES - LDL-RECEPTOR GENE MUTATION SCREENINGBiotechniques
Effect of the StuI polymorphism in the LDL receptor gene (Ala 370 to Thr) on lipid levels in healthy individuals.Clinical genetics
Dried template DNA, dried PCR oligonucleotides and mailing in 96-well plates: LDL receptor gene mutation screening.BioTechniques

1994

HANDLING OF LARGE (300X400-MM), THIN (0.4-MM) POLYACRYLAMIDE GELS AND RECOVERY AS DRIED GELSBiotechniques
EFFECT ON PLASMA-LIPID LEVELS OF DIFFERENT CLASSES OF MUTATIONS IN THE LOW-DENSITY-LIPOPROTEIN RECEPTOR GENE IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIAArteriosclerosis and Thrombosis
Handling of large (300 x 400 mm), thin (0.4 mm) polyacrylamide gels and recovery as dried gels.BioTechniques
Effect on plasma lipid levels of different classes of mutations in the low-density lipoprotein receptor gene in patients with familial hypercholesterolemia.Arteriosclerosis and thrombosis : a journal of vascular biology

1993

USE OF THE SINGLE-STRAND CONFORMATIONAL POLYMORPHISM METHOD TO DETECT RECURRENT AND NOVEL MUTATIONS IN THE LOW-DENSITY-LIPOPROTEIN RECEPTOR GENE IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA - DETECTION OF A NOVEL MUTATION ASP(200)-] GLYClinical Investigator
Use of the single-strand conformational polymorphism method to detect recurrent and novel mutations in the low-density lipoprotein receptor gene in patients with familial hypercholesterolaemia: detection of a novel mutation Asp200-->Gly.The Clinical investigator
THE MOLECULAR-GENETICS OF PEDIATRIC LIPID DISORDERS - RECENT PROGRESS AND FUTURE-RESEARCH DIRECTIONSPediatric Research
IDENTIFICATION OF RECURRENT AND NOVEL MUTATIONS IN EXON 4 OF THE LDL RECEPTOR GENE IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA IN THE UNITED-KINGDOMArteriosclerosis and Thrombosis
6 DNA POLYMORPHISMS IN THE LOW-DENSITY-LIPOPROTEIN RECEPTOR GENE - THEIR GENETIC-RELATIONSHIP AND AN EXAMPLE OF THEIR USE FOR IDENTIFYING AFFECTED RELATIVES OF PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIAJournal of Medical Genetics
Identification of common genetic polymorphisms that determine plasma levels of ApoAI and HDL-C.NATO ASI series. Series H, Cell biology
ASSOCIATION OF APOLIPOPROTEIN-E POLYMORPHISM WITH PLASMA-LEVELS OF HIGH-DENSITY-LIPOPROTEIN AND LIPOPROTEIN(A), AND EFFECT OF DIET IN HEALTHY-MEN AND WOMENNutrition Metabolism and Cardiovascular Diseases
Identification of recurrent and novel mutations in exon 4 of the LDL receptor gene in patients with familial hypercholesterolemia in the United Kingdom.Arteriosclerosis and thrombosis : a journal of vascular biology

1992

INTERACTION BETWEEN A POLYMORPHISM OF THE APO A-I PROMOTER REGION AND SMOKING DETERMINES PLASMA-LEVELS OF HDL AND APO A-IArteriosclerosis and Thrombosis
Interaction between a polymorphism of the apo A-I promoter region and smoking determines plasma levels of HDL and apo A-I.Arteriosclerosis and thrombosis : a journal of vascular biology
Characterization of deletions in the LDL receptor gene in patients with familial hypercholesterolemia in the United Kingdom.Arteriosclerosis and thrombosis : a journal of vascular biology
CHARACTERIZATION OF DELETIONS IN THE LDL RECEPTOR GENE IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA IN THE UNITED-KINGDOMArteriosclerosis and Thrombosis

1991

IDENTIFICATION OF THE 664 PROLINE TO LEUCINE MUTATION IN THE LOW-DENSITY-LIPOPROTEIN RECEPTOR IN 4 UNRELATED PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA IN THE UKClinical Genetics
PCR-based method to create a specific mutation as a reference for oligomelting.Clinical chemistry
Identification of the 664 proline to leucine mutation in the low density lipoprotein receptor in four unrelated patients with familial hypercholesterolaemia in the UK.Clinical genetics
PCR-BASED METHOD TO CREATE A SPECIFIC MUTATION AS A REFERENCE FOR OLIGOMELTINGClinical Chemistry

1989

POLYMORPHISM OF THE C-HA-RAS-1 PROTO-ONCOGENE IN SPORADIC AND FAMILIAL BREAST-CANCERInternational Journal of Cancer
A STUDY OF FAMILIAL HYPERCHOLESTEROLEMIA IN ICELAND USING RFLPSJournal of Medical Genetics

1987

SPECIFIC POLYPEPTIDE DIFFERENCES IN NORMAL VERSUS MALIGNANT HUMAN-BREAST TISSUES BY TWO-DIMENSIONAL ELECTROPHORESISBreast Cancer Research and Treatment

1986

Catabolite repressive effects of 5-thio-D-glucose on Saccharomyces cerevisiae.Journal of general microbiology

1985

SUPPRESSION OF TEMPERATURE SENSITIVE MUTATIONS IN ONCOGENE-RELATED CDC GENES IN SACCHAROMYCES-CEREVISIAE BY CATABOLITE REPRESSION RESISTANCE AND CYTOPLASMIC PETITE MUTATIONSCurrent Genetics

1984

ISOENZYME PATTERN AND SUBCELLULAR-LOCALIZATION OF HEXOKINASES IN HUMAN-BREAST CANCER AND NONPATHOLOGICAL BREAST-TISSUEInternational Journal of Cancer

Keywords for Specialisation:

Genetic epidemiology