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Valborg Guðmundsdóttir - Research Specialist

Valborg Guðmundsdóttir

–

Heilbrigðisvísindasvið

Valborg Guðmundsdóttir

Research Specialist

Location
Læknagarður / Lg-306
Email
valborgg [at] hi.is

Unit
Health Science Institute

Published works

2024

Proteomic prediction of incident heart failure and its main subtypesEuropean Journal of Heart Failure
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer’s disease

2023

A proteomic analysis of atrial fibrillation in a prospective longitudinal cohort (AGES-Reykjavik study)

2022

The Proteomic Profile of Interstitial Lung Abnormalities.American journal of respiratory and critical care medicine
Meals, Microbiota and Mental Health in Children and Adolescents (MMM-Study): A protocol for an observational longitudinal case-control study.PloS one
Heart failure risk is accurately predicted by certain serum proteins
A proteogenomic signature of age-related macular degeneration in blood.Nature communications
Proteomic Analysis Identifies Circulating Proteins Associated With Plasma Amyloid β and Incident DementiaBiological Psychiatry Global Open Science
A genome-wide association study of serum proteins reveals shared loci with common diseasesNature Communications
Coding and regulatory variants are associated with serum protein levels and diseaseNature Communications
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study.Cell reports. Medicine
Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts.Diabetes care

2021

Multiethnic Genome-Wide Association Study of Subclinical Atherosclerosis in Individuals With Type 2 Diabetes.Circulation. Genomic and precision medicine
A Proteogenomic Signature of Age-related Macular Degeneration in Blood
A genome-wide association study of serum proteins reveals shared loci with common diseases

2020

Antihypertensive medication uses and serum ACE2 levels
Circulating Protein Signatures and Causal Candidates for Type 2 DiabetesDiabetes
It’s in Our Blood: A Glimpse of Personalized MedicineTrends in Molecular Medicine
Serum levels of ACE2 are higher in patients with obesity and diabetesObesity Science & Practice
Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT studyGenome Medicine
ACE2 levels are altered in comorbidities linked to severe outcome in COVID-19
Coding and regulatory variants affect serum protein levels and common disease

2019

Deep serum proteomics reveal biomarkers and causal candidates for type 2 diabetes

2018

Co-regulatory networks of human serum proteins link genetics to diseaseScience
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study.Diabetologia
Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study.PloS one

2017

Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes.Frontiers in genetics
Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis.Diabetologia
Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.Nature

2016

Human gut microbes impact host serum metabolome and insulin sensitivity.Nature
Ranking factors involved in diabetes remission after bariatric surgery using machine-learning integrating clinical and genomic biomarkers.NPJ genomic medicine

2015

A proteomic study of the regulatory role for STAT-1 in cytokine-induced beta-cell death.Proteomics. Clinical applications
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.Nature

2014

The genome of a Late Pleistocene human from a Clovis burial site in western Montana.Nature

Keywords for Specialisation:

Systems biology

Type 2 diabetes