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Snævar Sigurðsson - Research Specialist
–
School of Health Sciences
Snævar Sigurðsson
Íslenska
Research Specialist
Location
Læknagarður / Lg-456
Email
snaevar [at] hi.is
Unit
BioMedical Center
ORCID site
https://orcid.org/0000-0003-4860-6311
Research portal – Snævar Sigurðsson
Published works
2023
Evaluating Prophylactic Effect of Bovine Colostrum on Intestinal Barrier Function in Zonulin Transgenic Mice
International Journal of Molecular Sciences
Aroylated phenylenediamine HO53 modulates innate immunity, histone acetylation and metabolism
Molecular Immunology
2022
The Novel Inducer of Innate Immunity HO53 Stimulates Autophagy in Human Airway Epithelial Cells
Journal of Innate Immunity
Ventilator-induced lung injury results in oxidative stress response and mitochondrial swelling in a mouse model
Laboratory Animal Research
2021
Metabolic and transcriptional changes across osteogenic differentiation of mesenchymal stromal cells
Bioengineering
2020
Azithromycin ameliorates sulfur dioxide-induced airway epithelial damage and inflammatory responses
Respiratory Research
Common and rare sequence variants influencing tumor biomarkers in blood
Cancer Epidemiology Biomarkers and Prevention
Azithromycin has lung barrier protective effects in a cell model mimicking ventilator-induced lung injury
Altex
2017
Sequence variants in ARHGAP15, COLQ and FAM155A associate with diverticular disease and diverticulitis
Nature Communications
Effect of sequence variants on variance in glucose levels predicts type 2 diabetes risk and accounts for heritability
Nature Genetics
2014
Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder
Genome Biology
Canine Hereditary Ataxia in Old English Sheepdogs and Gordon Setters Is Associated with a Defect in the Autophagy Gene Encoding RAB24
PLoS Genetics
Rare mutations associating with serum creatinine and chronic kidney disease
Human Molecular Genetics
2013
Genome-wide profiling of target genes for the systemic lupus erythematosus-associated transcription factors IRF5 and STAT4
Annals of the Rheumatic Diseases
Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing
Nature Genetics
Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B
Genome Biology
2012
Copy number expansion of the STX17 duplication in melanoma tissue from Grey horses.
BMC Genomics
2011
Mutation discovery in mice by whole exome sequencing
Genome Biology
Performance of microarray and liquid based capture methods for target enrichment for massively parallel sequencing and SNP discovery
PLoS ONE
Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping
PLoS Genetics
A candidate gene study of the type i interferon pathway implicates IKBKE and IL8 as risk loci for SLE
European Journal of Human Genetics
2010
Fine-mapping and mutation analysis of TRPM1
Briefings in Functional Genomics and Proteomics
Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus
Arthritis and Rheumatism
A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus
Annals of the Rheumatic Diseases
Identification of the bovine arachnomelia mutation by massively parallel sequencing implicates sulfite oxidase (SUOX) in bone development
PLoS Genetics
2009
Genome sequence, comparative analysis, and population genetics of the domestic horse
Science
2008
Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations
Journal of Medical Genetics
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus
Human Molecular Genetics
Variants of the interferon regulatory factor 5 gene regulate expression of IRF5 mRNA in atherosclerotic tissue but are not associated with myocardial infarction
Arteriosclerosis, Thrombosis, and Vascular Biology
A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5
Human Molecular Genetics
2007
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
Proceedings of the National Academy of Sciences of the United States of America
Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis
Arthritis and Rheumatism
An insertion-deletion polymorphism in the Interferon Regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases
Human Molecular Genetics
Corrigendum to ''A microarray system for genotyping 150 single nucleotide polymorphisms in the coding region of human mitochondrial DNA" [Genomics 87 (2006) 534-542] (DOI:10.1016/j.ygeno.2005.11.022)
Genomics
2006
A microarray system for genotyping 150 single nucleotide polymorphisms in the coding region of human mitochondrial DNA
Genomics
Genotyping of Single Nucleotide Polymorphisms by Minisequencing Using Tag Arrays
2005
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
American Journal of Human Genetics
2003
Quantitative evaluation by minisequencing and microarrays reveals accurate multiplexed SNP genotyping of whole genome amplified DNA
Nucleic Acids Research
2002
Multiplex SNP genotyping in pooled DNA samples by a four-colour microarray system.
Nucleic Acids Research
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