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Forsíða

Forsíða

Sævar Ingþórsson - Associate Professor

Sævar Ingþórsson

–

School of Health Sciences

Sævar Ingþórsson

Associate Professor

Location
Læknagarður
Email
saevari [at] hi.is

Unit
Faculty of Nursing and Midwifery

Published works

2022

Ventilator-induced lung injury results in oxidative stress response and mitochondrial swelling in a mouse modelLaboratory Animal Research
Cellular Plasticity and Heterotypic Interactions during Breast Morphogenesis and Cancer InitiationCancers

2021

Ventilator-induced lung-injury in mouse models: Is there a trap?Laboratory Animal Research

2020

Context-Dependent Function of Myoepithelial Cells in Breast Morphogenesis and NeoplasiaCurrent molecular biology reports
ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasionLaboratory Investigation
Azithromycin ameliorates sulfur dioxide-induced airway epithelial damage and inflammatory responsesRespiratory Research
Melflufen, a peptide‐conjugated alkylator, is an efficient anti‐neo‐plastic drug in breast cancer cell linesCancer Medicine

2019

Application of the D492 Cell Lines to Explore Breast Morphogenesis, EMT and Cancer Progression in 3D CultureJournal of Mammary Gland Biology and Neoplasia
Azithromycin induces epidermal differentiation and multivesicular bodies in airway epitheliaRespiratory Research
Innovative in vitro method to study ventilator induced lung injuryAltex
YKL-40/CHI3L1 facilitates migration and invasion in HER2 overexpressing breast epithelial progenitor cells and generates a niche for capillary-like network formationIn Vitro Cellular & Developmental Biology - Animal

2018

Chemical Mutagenesis and Fluorescence-Based High-Throughput Screening for Enhanced Accumulation of Carotenoids in a Model Marine Diatom Phaeodactylum tricornutumMarine Drugs

2017

Pathological changes in basement membranes and dermal connective tissue of skin from patients with hereditary cystatin C amyloid angiopathyDefault journal
Inhibition of PTP1B disrupts cell-cell adhesion and induces anoikis in breast epithelial cellsCell Death and Disease
Pathological changes in basement membranes and dermal connective tissue of skin from patients with hereditary cystatin C amyloid angiopathyLaboratory Investigation

2016

Epithelial Plasticity During Human Breast Morphogenesis and Cancer ProgressionJournal of Mammary Gland Biology and Neoplasia

2015

HER2 induced EMT and tumorigenicity in breast epithelial progenitor cells is inhibited by coexpression of EGFROncogene

2014

DeltaNp63 has a role in maintaining epithelial integrity in airway epitheliumPLoS ONE

2013

Expression and Functional Role of Sprouty-2 in Breast MorphogenesisPLoS ONE

2011

Selection for EGFR gene amplification in a breast epithelial cell line with basal-like phenotype and hereditary backgroundIn Vitro Cellular and Developmental Biology - Animal

2010

Fabrication of planar polymer waveguides for evanescent-wave sensing in aqueous environmentsMicroelectronic Engineering
Endothelial cells stimulate growth of normal and cancerous breast epithelial cells in 3D cultureBMC Research Notes

2009

Evanescent-wave fluorescence microscopy using symmetric planar waveguidesOptics Express

Keywords for Specialisation:

Stem Cell Biology

Embryonic stem cells

Induced pluripotent stem cells

3D cell culture