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Rafn Benediktsson - Professor
–
School of Health Sciences
Rafn Benediktsson
Íslenska
Professor
Head of Endocrinology
Location
LSH - Fossvogi
Phone
543 1000
Email
rafn [at] hi.is
Unit
Faculty of Medicine
Website
http://www.uni.hi.is/rafn
ORCID site
https://orcid.org/0000-0002-2954-9801
Research portal – Rafn Benediktsson
 
Courses 2024 - 2025
LÆK202F - Internal Medicine, theoretical
LÆK203F - Internal Medicine, Clinical
Education
1995
,
Ph.D.
,
University of Edinburgh
,
Medicine
1987
,
Kandídatspróf
,
University of Iceland
,
Medicine
Published works
2023
Data from Loss-of-Function Variants in the Tumor-Suppressor Gene <i>PTPN14</i> Confer Increased Cancer Risk
Supplementary Material from Loss-of-Function Variants in the Tumor-Suppressor Gene <i>PTPN14</i> Confer Increased Cancer Risk
Reynsla kvenna af því að greinast með meðgöngusykursýki og vitneskja þeirra um mikilvægi eftirfylgdar eftir fæðingu
Tímarit hjúkrunarfræðinga
2022
Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles
European Journal of Preventive Cardiology
2021
Loss-of-function variants in the tumor-suppressor gene PTPN14 confer increased cancer risk
Cancer Research
Ofþyngd þjóðar - hvað getum við gert?
Læknablaðið
Caffeine exposure from beverages and its association with self-reported sleep duration and quality in a large sample of Icelandic adolescents
Food and Chemical Toxicology
Ofþyngd þjóðar – hvað getum við gert?
Læknablaðið
Distinction between the effects of parental and fetal genomes on fetal growth
Nature Genetics
Distinction between the effects of parental and fetal genomes on fetal growth.
Nature Genetics
2020
FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease
Nature
2019
The number of adults with incident type 1 diabetes phenotype in Iceland is half the number in children – A population based study
Diabetes Research and Clinical Practice
GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures
Nature Communications
Lipoprotein(a) Concentration and Risks of Cardiovascular Disease and Diabetes.
Journal of the American College of Cardiology
Lipoprotein(a) Concentration and Risks of Cardiovascular Disease and Diabetes
Journal of the American College of Cardiology
A PRPH splice-donor variant associates with reduced sural nerve amplitude and risk of peripheral neuropathy
Nature Communications
GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures.
Nature Communications
Sequence variants associating with urinary biomarkers
Human Molecular Genetics
Publisher Correction
Nature Communications
2018
Sjúkratilfelli: Truflun á starfsemi heiladinguls vegna ópíóíða
Læknablaðið
Sequence variants associating with urinary biomarkers
Human Molecular Genetics
2017
Effect of sequence variants on variance in glucose levels predicts type 2 diabetes risk and accounts for heritability
Nature Genetics
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
Diabetes
Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations
npj Genomic Medicine
Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations
npj Genomic Medicine
2015
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
Nature Genetics
The epidemiology of pituitary adenomas in Iceland, 1955-2012
European Journal of Endocrinology
HbA1c 7% verður 53 mmól/mól -ný eining frá 1. mars 2015
Laeknabladid
2014
Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes
PLoS Genetics
Adipose tissue, muscle, and function
Diabetes Care
Frá embætti landlæknis. Vanstarfsemi í skjaldkirtli
Laeknabladid
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
Nature Genetics
Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes
Nature Genetics
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
Nature Genetics
2013
Similar decline in mortality rate of older persons with and without type 2 diabetes between 1993 and 2004 the Icelandic population-based Reykjavik and AGES-Reykjavik cohort studies
BMC Public Health
2012
Early life residency associated with the risk of developing type 2 diabetes - The population-based Reykjavík Study.
Læknablaðið
Greining, medferd og eftirlit háprýstings.
Læknabladid
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
PLoS Genetics
Retinopathy in old persons with and without diabetes mellitus
Diabetologia
Tengsl búsetu fyrstu 20 æviárin við áhættu á sykursýki af tegund 2
Laeknabladid
Greining, meðferð og eftirlit háþrýstings
Laeknabladid
A genome-wide association search for type 2 diabetes genes in African Americans.
PLoS ONE
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Nature Genetics
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases
PLoS Genetics
2011
Erratum
Nature Genetics
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits
PLoS Genetics
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
Diabetes
Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1
American Journal of Human Genetics
Effects of statin medication on mortality risk associated with type 2 diabetes in older persons: the population-based AGES-Reykjavik Study
BMJ Open
Meðhöndlun sykursýki af tegund 1 hjá fullorðnum - er búið að leysa málið?
Laeknabladid
2010
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Nature Genetics
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Nature Genetics
Erratum
Nature Genetics
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
Nature Genetics
2009
Sjálfsumönnun og sjálfsefling fólks meö sykursýki Tillaga aö nálgun meö leiöbeinandi matskvöröum - yfirlitsgrein
Laeknabladid
Instruments to tailor care of people with type 2 diabetes
Journal of Advanced Nursing
Sjálfsumönnun og sjálfsefling fólks með sykursýki: tillaga að nálgun með leiðbeinandi matskvörðum – yfirlitsgrein.
Læknablaðið
Unfavourable risk factors for type 2 diabetes mellitus are already apparent more than a decade before onset in a population-based study of older persons
European Journal of Epidemiology
Parental origin of sequence variants associated with complex diseases
Nature
2008
The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm
Nature Genetics
Reliability and validity of the Icelandic version of the problem area in diabetes (PAID) scale
International Journal of Nursing Studies
Einkenni og teikn fótameins hjá íslenskum sjúklingum meǒ sykursýki af tegund 2
Laeknabladid
2007
Infant feeding patterns and midlife erythrocyte sedimentation rate
Acta Paediatrica, International Journal of Paediatrics
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
Nature Genetics
Outcomes of educational interventions in type 2 diabetes
Patient Education and Counseling
Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution
Nature Genetics
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
Nature Genetics
Algengi sykursýki af tegund tvö á Islandi 1967-2002.
Læknabladid
2006
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
Nature Genetics
2005
Mótefnatengd sykursýki af tegund 2 á Islandi
Læknabladid
2004
Mótefnatengd sykursýki af tegund 2 á Íslandi: algengi, svipgerð og skyldleiki einstaklinga.
Læknablaðið
Association between size at birth, truncal fat and obesity in adult life and its contribution to blood pressure and coronary heart disease; study in a high birth weight population
European Journal of Clinical Nutrition
Maximizing the benefit of treatment in mild hypertension
QJM - Monthly Journal of the Association of Physicians
2003
Þrjár einfaldar leiðir til nákvæmari greiningar háþrýstings
Læknablaðið
Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2
American Journal of Human Genetics
2002
Size at birth and coronary artery disease in a population with high birth weight
American Journal of Clinical Nutrition
Size at birth and coronary heart disease in a population of high birth weight.
American Journal of Clinical Nutrition
Size at birth and glucose intolerance in a relatively genetically homogeneous, high-birth weight population
American Journal of Clinical Nutrition
Háþrýstingur með kalíumbresti : óvenjuleg sýnd litfíklaæxlis : sjúkratilfelli
Læknablaðið
Relationship between size at birth and hypertension in a genetically homogenous population of high birth weight
Journal of Hypertension
2000
Transfer and metabolism of prostaglandin E
2
in the dual perfused human placenta
Placenta
Transfer and metabolism of prostaglandin E2 in the dually perfused human placenta.
Placenta
1998
Understanding human parturition [6]
Lancet
Management of the unexpected result
Postgraduate Medical Journal
Meðferð sykursýki af tegund 2 : bresk tímamótarannsókn styður góða blóðsykur- og blóðþrýstingsstjórn [ritstjórnargrein]
Læknablaðið
Tissue-specific messenger ribonucleic acid expression of 11β- hydroxysteroid dehydrogenase types 1 and 2 and the glucocorticoid receptor within rat placenta suggests exquisite local control of glucocorticoid action
Endocrinology
1997
Placental 11ß-hydroxysteroid dehydrogenase: A key regulator of human fetal glucocorticoid exposure.
Clinical Endocrinology
Placental 11β-hydroxysteroid dehydrogenase
Clinical Endocrinology
Lack of effect of nicotine or ethanol on the activity of 11β- hydroxysteroid dehydrogenase type 2
Journal of Steroid Biochemistry and Molecular Biology
1996
11β-Hydroxysteroid dehydrogenases
Essays in Biochemistry
11β-Hydroxysteroid dehydrogenases
Steroids
11β-Hydroxysteroid dehydrogenase type 2 in the rat corpus luteum
Endocrinology
Essential hypertension
Clinical Endocrinology
Protein intake in pregnancy, placental glucocorticoid metabolism and the programming of hypertension in the rat
Placenta
1995
Ambulatory blood pressure monitoring
Journal of Human Hypertension
Fetal osteocalcin levels are related to placental 11β-hydroxysteroid dehydrogenase activity in humans
Clinical Endocrinology
Placental 11β-hydroxysteroid dehydrogenase and the programming of hypertension
Journal of Steroid Biochemistry and Molecular Biology
Cellular selectivity of aldosterone action
Current Opinion in Nephrology and Hypertension
1994
Apparent mineralocorticoid excess
Journal of Human Hypertension
1993
Congenital and acquired syndromes of apparent mineralocorticoid excess
Journal of Steroid Biochemistry and Molecular Biology
Glucocorticoid exposure in utero
The Lancet
Dysfunction of placental glucocorticoid barrier
The Lancet
1992
Dexamethasone treatment of pregnant rats leads to raised blood pressure in the offspring
Journal of Hypertension
11β-Hydroxysteroid dehydrogenase in the rat ovary
Journal of Endocrinology
11ß-hydroxysteroid dehydrogenase in the ovary: High expression in the oocyte.
Journal of Endocrinological Investigation
Blood pressure and birth weight
Journal of Hypertension
1991
Natural history of chronic left ventricular aneurysm; A population based cohort study
Journal of Clinical Epidemiology
Liquorice
The Lancet
1989
Cod liver oil and atherosclerosis.
Læknablaðið
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