Skip to main content

ÍS
EN

Forsíða

Forsíða

Magnús Karl Magnússon - Professor

Magnús Karl Magnússon

–

School of Health Sciences

Magnús Karl Magnússon

Professor

Professor of Pharmacology & Toxicology

Location
Sturlugata 8
Email
magnuskm [at] hi.is

Unit
Faculty of Medicine
Website
http://lifvisindi.hi.is/magnus_karl_magnusson

ORCID site
https://orcid.org/0000-0001-8593-4934
Research portal – Magnús Karl Magnússon
Under construction throughout the autumn semester 2023

Published works

2022

Genetic architecture of band neutrophil fraction in IcelandCommunications Biology

2021

A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis.Communications biology
Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptorCommunications Biology

2020

Expression of ncRNAs on the DLK1-DIO3 Locus Is Associated With Basal and Mesenchymal Phenotype in Breast Epithelial Progenitor Cells.Frontiers in cell and developmental biology
Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis.Communications biology

2019

[The Nobel Prize in Medicine 2019 - The cellular oxygen sensing mechanism].Laeknabladid
[Opioid overdose following voriconazole treatment - case report].Laeknabladid
Improved long-term survival following pulmonary resections for non-small cell lung cancer: results of a nationwide study from Iceland.Annals of translational medicine

2018

MiR-203a is differentially expressed during branching morphogenesis and EMT in breast progenitor cells and is a repressor of peroxidasin.Mechanisms of development
[Views of Icelandic women towards genetic counseling - and testing of BRCA2 mutations].Laeknabladid
A truncating mutation in EPOR leads to hypo-responsiveness to erythropoietin with normal haemoglobin.Communications biology

2017

Reduced anticoagulation variability in patients on warfarin monitored with Fiix-prothrombin time associates with reduced thromboembolism: The Fiix-trial.Journal of Thrombosis and Thrombolysis
Inhibition of PTP1B disrupts cell-cell adhesion and induces anoikis in breast epithelial cells.Cell Death & Disease

2016

Abstract B08: Expression of noncoding RNAs on the DLK1-DIO1 locus in EMT and breast cancerCancer Research
[Medical education in Iceland, 140th anniversary[Editorial]].Laeknabladid

2015

Context-Dependent Function of Myoepithelial Cells in Breast Morphogenesis and Neoplasia.Current molecular biology reports
Contribution of epithelial-to-mesenchymal transition to phenotypic changes in idiopathic interstitial pneumonias1.5 Diffuse Parenchymal Lung Disease
MicroRNA-200c-141 and ∆Np63 are required for breast epithelial differentiation and branching morphogenesis.Developmental biology
KIT and PDGFRA mutations and the risk of GI stromal tumor recurrence.Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Basal cells of the human airways acquire mesenchymal traits in idiopathic pulmonary fibrosis and in cultureLaboratory Investigation

2014

Clinical phenotype in heterozygote and biallelic Bernard-Soulier syndrome--a case control study.American journal of hematology
deltaNp63 has a role in maintaining epithelial integrity in airway epithelium.PloS one
Functional Role of the microRNA-200 Family in Breast Morphogenesis and Neoplasia.Genes

2013

[Investing in knowledge for the future].Laeknabladid
Expression and functional role of sprouty-2 in breast morphogenesis.PloS one

2012

Endothelial-rich microenvironment supports growth and branching morphogenesis of prostate epithelial cells.The Prostate
[Genetically modified plants; a threat to human health?].Laeknabladid
Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.Journal of the American College of Cardiology

2011

Risk of recurrence of gastrointestinal stromal tumour after surgery: an analysis of pooled population-based cohorts.The Lancet. Oncology
Endothelial Induced EMT in Breast Epithelial Cells with Stem Cell PropertiesPLoS ONE

2010

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.Nature genetics
Endothelial cells stimulate growth of normal and cancerous breast epithelial cells in 3D cultureBMC Research Notes
Selection for EGFR gene amplification in a breast epithelial cell line with basal-like phenotype and hereditary background.In vitro cellular & developmental biology. Animal

2007

Clinical study on gastrointestinal stromal tumors (GIST) in Iceland, 1990-2003.Digestive diseases and sciences

2005

Gastrointestinal stromal tumors in Iceland, 1990-2003: The Icelandic GIST study, a population-based incidence and pathologic risk stratification studyInternational Journal of Cancer
Stem cell biology and the cellular pathways of carcinogenesis.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica

2004

Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner.Blood

2003

Gene expression analysis in mastocytosis reveals a highly consistent profile with candidate molecular markers.The Journal of allergy and clinical immunology

2002

Activity of STI571 in chronic myelomonocytic leukemia with a platelet-derived growth factor beta receptor fusion oncogene.Blood

2001

Modulation of cell interactions with extracellular matrix by lysophosphatidic acid and sphingosine 1-phosphateProstaglandins & Other Lipid Mediators

1999

Sphingosine 1-phosphate stimulates fibronectin matrix assembly through a Rho-dependent signal pathway.Blood

1998

Fibronectin: structure, assembly, and cardiovascular implications.Arteriosclerosis, thrombosis, and vascular biology

1997

Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction.Molecular biology of the cell

1994

Low iron-binding capacity as a risk factor for myocardial infarction.Circulation

1991

Different mechanisms of homologous and heterologous desensitization of thrombin-induced endothelial prostacyclin production.European journal of pharmacology

1989

Endothelial inositol phosphate generation and prostacyclin production in response to G-protein activation by AlF4-.The Biochemical journal

Keywords for Specialisation:

Epithelial biology