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Forsíða

Forsíða

Ingibjörg Harðardóttir - Professor

Ingibjörg Harðardóttir

–

School of Health Sciences

Ingibjörg Harðardóttir

Professor

Lipid metabolism, nutrition

Location
Læknagarður / Lg-543
Email
ih [at] hi.is

Unit
Biochemistry
Website
http://lifvisindi.hi.is/staff/ingibjorg-hardardottir

Published works

2023

Geobarrettin D, a Rare Herbipoline-Containing 6-Bromoindole Alkaloid from Geodia barrettiMolecules

2022

Dietary Fish Oil Increases the Number of CD11b⁺CD27⁻ NK Cells at the Inflammatory Site and Enhances Key Hallmarks of Resolution of Murine Antigen-Induced PeritonitisJournal of Inflammation Research
Dietary Fish Oil Increases the Number of CD11b+ CD27- NK Cells at the Inflammatory Site and Enhances Key Hallmarks of Resolution of Murine Antigen-Induced PeritonitisJournal of Inflammation Research

2021

Seaweed extract improves carbohydrate metabolism in overweight and obese adultsCurrent Nutrition and Food Science
Emu Oil and Saireito in combination reduce tumour development and clinical indicators of disease in a mouse model of colitis-associated colorectal cancerBiomedicine and Pharmacotherapy

2020

Bromotryptamine and Imidazole Alkaloids with Anti-inflammatory Activity from the Bryozoan <i>Flustra foliacea</i>Journal of Natural Products
Anti-inflammatory and proresolving effects of the omega-6 polyunsaturated fatty acid adrenic acidJournal of Immunology
Docosahexaenoic Acid Modulates NK Cell Effects on Neutrophils and Their CrosstalkFrontiers in Immunology
The BLIMP1—EZH2 nexus in a non-Hodgkin lymphomaOncogene
The BLIMP1—EZH2 nexus in a non-Hodgkin lymphomaOncogene

2019

Exopolysaccharides from Cyanobacterium aponinum induce a regulatory dendritic cell phenotype and inhibit SYK and CLEC7A expression in dendritic cells, T cells and keratinocytesInternational Immunopharmacology

2018

6-Bromoindole Derivatives from the Icelandic Marine Sponge <em>Geodia barretti</em>: Isolation and Anti-Inflammatory ActivityMarine Drugs
6-Bromoindole Derivatives from the Icelandic Marine Sponge Geodia barretti: Isolation and Anti-Inflammatory ActivityMarine Drugs
Natural killer cells play an essential role in resolution of antigen-induced inflammation in miceMolecular Immunology

2017

Lipophilic fractions from the marine sponge halichondria sitiens decrease secretion of pro-inflammatory cytokines by dendritic cells and decrease their ability to induce a Th1 type response by allogeneic CD4⁺ T cellsPharmaceutical Biology

2016

A polysaccharide fraction from Achillea millefolium increases cytokine secretion and reduces activation of Akt, ERK and NF-κB in THP-1 monocytesCarbohydrate Polymers
Acute phase inflammation is characterized by rapid changes in plasma/peritoneal fluid N-glycosylation in miceGlycoconjugate Journal

2015

Dendritic cells matured in the presence of the lycopodium alkaloid annotine direct T cell responses toward a Th2/Treg phenotypePhytomedicine
Dendritic cells matured in the presence of the lycopodium alkaloid annotine direct T cell responses towards a Th2/Treg phenotype.Phytomedicine
Differential mobility separation of leukotrienes and protectinsAnalytical Chemistry

2014

A heteroglycan from the cyanobacterium Nostoc commune modulates LPS-induced inflammatory cytokine secretion by THP-1 monocytes through phosphorylation of ERK1/2 and AktPhytomedicine
Murine antigen-induced inflammation-A model for studying induction, resolution and the adaptive phase of inflammationJournal of Immunological Methods
Dietary omega-3 fatty acids enhance the B1 but not the B2 cell immune response in mice with antigen-induced peritonitisJournal of Nutritional Biochemistry

2013

Dietary fish oil increases the proportion of a specific neutrophil subpopulation in blood and total neutrophils in peritoneum of mice following endotoxin-induced inflammationJournal of Nutritional Biochemistry
Dietary fish oil reduces the acute inflammatory response and enhances resolution of antigen-induced peritonitisJournal of Nutritional Biochemistry

2012

Dietary fish oil decreases the proportion of classical monocytes in blood in healthy mice but increases their proportion upon induction of inflammationJournal of Nutrition
Two circulating neutrophil populations in acute inflammation in miceInflammation Research

2011

Ethanol extract from birch bark (Betula pubescens) suppresses human dendritic cell mediated Th1 responses and directs it towards a Th17 regulatory response in vitroImmunology Letters
Aqueous extracts from Menyanthes trifoliate and Achillea millefolium affect maturation of human dendritic cells and their activation of allogeneic CD4 ⁺ T cells in vitroJournal of Ethnopharmacology

2010

Immunomodulating effects of extracts from Icelandic marine invertebratesPlanta Medica

2008

Dietary fish oil decreases secretion of T helper (Th) 1-type cytokines by a direct effect on murine splenic T cells but enhances secretion of a Th2-type cytokine by an effect on accessory cellsBritish Journal of Nutrition
Dietary fish oil increases IL-4 secretion by murine splenocytes by an effect on accessory cellsProceedings of the Nutrition Society
The effects of dietary fish oil on chemokine secretion by murine peritoneal and spleen cellsProceedings of the Nutrition Society

2007

Mucosal tolerance to KLH reduces BSA-induced arthritis in rats - An indication of bystander suppressionJournal of Clinical Immunology
Dietary fish oil increases the number of splenic macrophages secreting TNF-α and IL-10 but decreases the secretion of these cytokines by splenic T cells from miceJournal of Nutrition
Dietary fish oil increases the number of splenic macrophages secreting TNF-alpha and IL-10 but decreases the secretion of these cytokines by splenic T cells from mice.The Journal of nutrition
Omega-3 polyunsaturated fatty acids increase TNF-a secretion but do not affect IL-10 secretion by murine resident and elicited peritoneal macrophages in vitroLipids
The effects of omega-3 polyunsaturated fatty acids on TNF-alpha and IL-10 secretion by murine peritoneal cells in vitro.Lipids
Positive association between DNA strand breaks in peripheral blood mononuclear cells and polyunsaturated fatty acids in red blood cells from womenNutrition and Cancer

2006

Positive association between plasma antioxidant capacity and n-3 PUFA in red blood cells from Icelandic women.Lipids
Positive association between plasma antioxidant capacity and n-3 PUFA in red blood cells from Icelandic women.Lipids

2002

Dietary fish oil increases tumor necrosis factor secretion but decreases interleukin-10 secretion by murine peritoneal macrophages.The Journal of nutrition
Verndandi áhrif lýsisríks fæðis eftir sýkingar eru óháð íkomustað bakteríannaLæknablaðið
Áhrif lýsisríks fæðis á lifun músa eftir sýkingu með Klebsiella pneumoniae eða Streptococcus pneumoniaeLæknablaðið

2001

Áhrif lýsisneyslu á bakteríuvöxt in vivoLæknablaðið

1998

Eneficial effects of cytokine induced hyperlipidemiaZeitschrift fur Ernahrungswissenschaft

1997

Lýsisneysla eykur lifun músa eftir sýkingu með Klebsiella pneumoniaeLæknablaðið
LPS and cytokines regulate extra hepatic mRNA levels of apolipoproteins during the acute phase response in Syrian hamstersBiochimica et Biophysica Acta - Lipids and Lipid Metabolism
Endotoxin and cytokines regulate extrahepatic mRNA levels of apoproteins in Syrian hamstersBiochimica et biophysica acta
Dieatry fish-oil supple-mentation increases survival in mice following Klebsiella Pneumoniae infectionScandinavian Journal of Infectious Diseases

1996

Endotoxin and cytokines decrease serum levels and extra hepatic protein and mRNA levels of cholesteryl ester transfer protein in Syrian hamstersJournal of Clinical Investigation

1995

Cytokine-induced alterations in hepatic lipid metabolism
Effects of endotoxin on lipid metabolism
Effects of endotoxin on lipid metabolismBiochemical Society Transactions
Dietary n-3 poly-unsaturated fatty acids modify Syrian hamster platelet and macrophage pospholipid fatty acyl composition and eicosanoid synthesis - A controlled studyBiochimica et biophysica acta

1994

Effects of TNF, IL-1, and the combination of both cytokines on cholesterol metabolism in Syrian hamstersLymphokine and Cytokine Research
Endotoxin and cytokines increase hepatic messenger RNA levels and serum concentrations of apolipoprotein J (clusterin) in Syrian hamstersJournal of Clinical Investigation
Effects of endotoxin and cytokines on lipid metabolismCurrent Opinion in Lipidology

1993

Effect of endotoxin on cholesterol biosynthesis and distribution in serum lipoproteins in Syrian hamstersJournal of Lipid Research
Dietary arachidonate enhances tissue arachidonate levels and eicosanoid production in Syrian hamstersJournal of Nutrition
The effects of dietary n-3 polyunsaturated fatty acids and cyclic AMP-elevating agents on tumor necrosis factor production by murine-resident and thioglycollate-elicited peritoneal macrophagesThe Journal of Nutritional Biochemistry

1992

Increasing the dietary (n-3) to (n-6) polyunsaturated fatty acid ratio increases tumor necrosis factor production by murine resident peritoneal macrophages without an effect on elicited peritoneal macrophagesJournal of Nutrition
Cytokines stimulate lipolysis and decrease lipoprotein lipase activity in cultured fat cells by a prostaglandin independent mechanismBiochemical and Biophysical Research Communications

1991

Tumor necrosis factor production by murine resident peritoneal macrophages is enhanced by dietary n−3 polyunsaturated fatty acidsBiochimica et Biophysica Acta (BBA) - Molecular Cell Research
Tumor necrosis factor production by murine resident peritoneal macrophages is enhanced by dietary n-3 polyunsaturated fatty acidsBBA - Molecular Cell Research
Effect of increasing the dietary (n-3) to (n-6) polyunsaturated fatty acid ratio on murine liver and peritoneal cell fatty acids and eicosanoid formationJournal of Nutrition

1988

Extraction of Lipid and Cholesterol from Fish Muscle with Supercritical FluidsJournal of Food Science

Keywords for Specialisation:

Resolution of inflammation