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Forsíða

Forsíða

Hákon Hrafn Sigurðsson - Professor

Hákon Hrafn Sigurðsson

–

School of Health Sciences

Hákon Hrafn Sigurðsson

Professor

Location
Hagi / Ha-313
Phone
525 - 5821
Email
hhs [at] hi.is

Unit
Faculty of Pharmaceutical Sciences
Website
http://www.hi.is/~hhs
Published Work
Hákon Hrafn Sigurðsson - published work

Curriculum Vitae
Hákon Hrafn Sigurðsson - Curriculum Vitae
ORCID site
https://orcid.org/0000-0003-4074-9182
Research portal – Hákon Hrafn Sigurðsson

Published works

2024

Chitosan and Anionic Solubility Enhancer Sulfobutylether-β-Cyclodextrin-Based Nanoparticles as Dexamethasone Ophthalmic Delivery System for Anti-Inflammatory TherapyPharmaceutics
Drug-like properties and topical delivery of rapalogs and tacrolimus in ophthalmologyJournal of Drug Delivery Science and Technology

2023

Anomalous Properties of Cyclodextrins and Their Complexes in Aqueous SolutionsMaterials

2022

Chitosan/sulfobutylether-β-cyclodextrin based nanoparticles coated with thiolated hyaluronic acid for indomethacin ophthalmic deliveryInternational Journal of Pharmaceutics

2021

Age-related ocular conditionsInternational Journal of Pharmaceutics

2020

In Vitro and Ex Vivo Evaluation of Nepafenac-Based Cyclodextrin Microparticles for Treatment of Eye InflammationNanomaterials

2019

Nepafenac-Loaded Cyclodextrin/Polymer Nanoaggregates: A New Approach to Eye Drop FormulationMaterials
Cyclodextrin–Amphiphilic Copolymer Supramolecular Assemblies for the Ocular Delivery of NatamycinNanomaterials

2016

Cyclodextrin-based telmisartan ophthalmic suspension: Formulation development for water-insoluble drugsInternational Journal of Pharmaceutics

2013

Mucus as a barrier to lipophilic drugsInternational Journal of Pharmaceutics

2012

Cross-linked hydroxypropyl-β-cyclodextrin and γ-cyclodextrin nanogels for drug deliveryCarbohydrate Polymers

2011

Drug loading in cyclodextrin polymersJournal of Inclusion Phenomena and Macrocyclic Chemistry

2010

γ-Cyclodextrin hydrogels and semi-interpenetrating networks for sustained delivery of dexamethasoneCarbohydrate Polymers
Cyclodextrin solubilization of carbonic anhydrase inhibitor drugsEuropean Journal of Pharmaceutics and Biopharmaceutics

2008

Topical drug delivery to the posterior segment of the eyePharmazie

2007

Dexamethasone delivery to posterior segment of the eyeJournal of Inclusion Phenomena and Macrocyclic Chemistry
Topical and systemic absorption in delivery of dexamethasone to the anterior and posterior segments of the eyeActa Ophthalmologica Scandinavica
Dexamethasone delivery to posterior segment of the eyeJournal of Inclusion Phenomena and Macrocyclic Chemistry

2006

Assessment of mucoadhesion by a resonant mirror biosensorInternational Journal of Pharmaceutics
Ocular powderJournal of Ocular Pharmacology and Therapeutics

2005

Cyclodextrin formulation of dorzolamide and its distribution in the eye after topical administrationJournal of Controlled Release

2004

Preparation and in vivo evaluation of aqueous dorzolamide/RMbCD eye drop solutionsProceedings of the 12th International Cyclodextrin Symposium
Reduced formulation bulk of cyclodextrin complexes through addition and subsequent removal of volatile acids or basesProceedings of the 12th International Cyclodextrin Symposium
Preparation of solid drug/cyclodextrin complexes of acidic and basic drugsPharmazie

2003

The effects of cyclodextrins on topical delivery of hydrocortisoneS.T.P. Pharma Sciences

2002

Mucoadhesive sustained drug delivery system based on cationic polymer and anionic cyclodextrin/triclosan complexJournal of Inclusion Phenomena
Cyclodextrins and drug permeability through semi-permeable cellophane membranesInternational Journal of Pharmaceutics
The effects of cyclodextrins on hydrocortisone permeability through semi-permeable membranesJournal of Inclusion Phenomena
Cyclodextrins and drug permeability through semi-permeable cellophane membranesInternational Journal of Pharmaceutics

2001

Cyclodextrin solubilization of benzodiazepinesInternational Journal of Pharmaceutics
The effect of HPbCD on hydrocortisone permeability through semi-permeable cellophane membranes Proceedings of the international symposium on controlled release of bioactive materials
Sustained drug delivery system based on a cationic polymer and an anionic drug/cyclodextrin complexPharmazie

2000

Formulation and preliminary clinical testing of midazolam-cyclodextrin nasal spray Proceedings of the international symposium on controlled release of bioactive materials
Midazolam solubilized with cyclodextrins: formulation of a nasal spray and preliminary clinical testingProceedings of the 10th International Cyclodextrin Symposium

1998

Cyclodextrins as co-enhancers in dermal and transdermal drug deliveryPharmazie

Keywords for Specialisation:

Pharmaceutics and Physical Pharmacy

Ocular drug delivery

Drug transport through membranes

Mucoadhesion (polymers