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Bárður Sigurgeirsson - Professor
–
School of Health Sciences
Bárður Sigurgeirsson
Íslenska
Professor
Dermatologist
Phone
5204444
Email
bsig [at] hi.is
Unit
Faculty of Medicine
Website
http://www.hls.is
ORCID site
https://orcid.org/0000-0002-9733-9742
Research portal – Bárður Sigurgeirsson
Courses 2023 - 2024
LÆK407F - Dermatology and sexually transmitted diseases
Published works
2023
Supplementary Material from Loss-of-Function Variants in the Tumor-Suppressor Gene
PTPN14
Confer Increased Cancer Risk
Supplementary Material from Loss-of-Function Variants in the Tumor-Suppressor Gene
PTPN14
Confer Increased Cancer Risk
Data from Loss-of-Function Variants in the Tumor-Suppressor Gene
PTPN14
Confer Increased Cancer Risk
Data from Loss-of-Function Variants in the Tumor-Suppressor Gene
PTPN14
Confer Increased Cancer Risk
2022
Efficacy, tolerability, patient usability, and satisfaction with a 2 mL pre-filled syringe containing secukinumab 300 mg in patients with moderate to severe plaque psoriasis: results from the phase 3 randomized, double-blind, placebo-controlled ALLURE study
Journal of Dermatological Treatment
Secukinumab demonstrates efficacy, safety, and tolerability upon administration by 2 ml autoinjector in adult patients with plaque psoriasis: 52‐week results from MATURE, a randomized, placebo‐controlled trial
Dermatologic Therapy
2021
Loss-of-Function Variants in the Tumor-Suppressor Gene PTPN14 Confer Increased Cancer Risk
Cancer Research
2020
Comparison of pharmacokinetics, safety and tolerability of secukinumab administered subcutaneously using different delivery systems in healthy volunteers and in psoriasis patients.
British journal of clinical pharmacology
FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease.
Nature
Genome-wide meta-analysis identifies eight new susceptibility loci for cutaneous squamous cell carcinoma.
Nature communications
2019
A survey among dermatologists: diagnostics of superficial fungal infections – what is used and what is needed to initiate therapy and assess efficacy?
Journal of the European Academy of Dermatology and Venereology
Effective treatment with balneophototherapy and narrowband UVB monotherapy reduces skin homing Th17/Tc17 and Th22/Tc22 effector cells in peripheral blood in patients with psoriasis.
Journal of dermatological science
2018
Association of BRCA2 K3326* With Small Cell Lung Cancer and Squamous Cell Cancer of the Skin.
Journal of the National Cancer Institute
2017
Patient-reported Outcomes and Clinical Response in Patients with Moderate-to-severe Plaque Psoriasis Treated with Tonsillectomy: A Randomized Controlled Trial.
Acta dermato-venereologica
Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations.
NPJ genomic medicine
A 5-year randomized trial on the safety and efficacy of pimecrolimus in atopic dermatitis: a critical appraisal - author response.
The British journal of dermatology
Patient-reported outcomes from two randomised studies comparing once-weekly application of amorolfine 5% nail lacquer to other methods of topical treatment in distal and lateral subungual onychomycosis.
Mycoses
Secukinumab re-initiation achieves regain of high response levels in patients who interrupt treatment for moderate to severe plaque psoriasis.
The British journal of dermatology
2016
HLA-Cw6 homozygosity in plaque psoriasis is associated with streptococcal throat infections and pronounced improvement after tonsillectomy: A prospective case series.
Journal of the American Academy of Dermatology
Application of cosmetic nail varnish does not affect the antifungal efficacy of amorolfine 5% nail lacquer in the treatment of distal subungual toenail onychomycosis: results of a randomised active-controlled study and in vitro assays.
Mycoses
Throat Infections are Associated with Exacerbation in a Substantial Proportion of Patients with Chronic Plaque Psoriasis.
Acta dermato-venereologica
Secukinumab improves patient-reported psoriasis symptoms of itching, pain, and scaling: results of two phase 3, randomized, placebo-controlled clinical trials.
International journal of dermatology
2015
New basal cell carcinoma susceptibility loci.
Nature communications
Authors' Response.
Pediatrics
Safety and efficacy of pimecrolimus in atopic dermatitis: a 5-year randomized trial.
Pediatrics
Secukinumab Improves Physical Function in Subjects With Plaque Psoriasis and Psoriatic Arthritis: Results from Two Randomized, Phase 3 Trials.
Journal of drugs in dermatology : JDD
Cutaneous melanoma in Iceland: changing Breslow's tumour thickness.
Journal of the European Academy of Dermatology and Venereology : JEADV
2014
Analysis of stranded information using an automated procedure for strand specific RNA sequencing.
BMC genomics
Psoriatic nail disease, a predictor of psoriatic arthritis.
The British journal of dermatology
Sequencing degraded RNA addressed by 3' tag counting.
PloS one
Psoriasis treatment: faster and long-standing results after bathing in geothermal seawater. A randomized trial of three UVB phototherapy regimens.
Photodermatology, photoimmunology & photomedicine
The age and genomic integrity of neurons after cortical stroke in humans.
Nature neuroscience
Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma.
Human molecular genetics
Secukinumab in plaque psoriasis--results of two phase 3 trials.
The New England journal of medicine
Secukinumab improves the signs and symptoms of moderate-to-severe plaque psoriasis in subjects with involvement of hands and/or feet: subanalysis of a randomized, double-blind, placebo-controlled, phase 2 dose-ranging study.
Journal of the European Academy of Dermatology and Venereology : JEADV
The prevalence of onychomycosis in the global population: a literature study.
Journal of the European Academy of Dermatology and Venereology : JEADV
2013
The role of Th17/Tc17 peripheral blood T cells in psoriasis and their positive therapeutic response.
Scandinavian journal of immunology
A phase II, randomized, double-blind, placebo-controlled, parallel group, dose-ranging study to investigate the efficacy and safety of 4 dose regimens of oral albaconazole in patients with distal subungual onychomycosis.
A variant in FTO shows association with melanoma risk not due to BMI.
Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study.
Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled, phase II regimen-finding study.
2012
Improvement of psoriasis after tonsillectomy is associated with a decrease in the frequency of circulating T cells that recognize streptococcal determinants and homologous skin determinants.
Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: a randomised, double-blind, placebo-controlled, phase II regimen-finding study.
Therapeutic potential of TDT 067 (terbinafine in Transfersome): a carrier-based dosage form of terbinafine for onychomycosis.
2011
[Erythemogenic UV rays].
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility.
[UV-index in Iceland during the summer of 2010].
Efficacy, safety and tolerability of topical terbinafine nail solution in patients with mild-to-moderate toenail onychomycosis: results from three randomized studies using double-blind vehicle-controlled and open-label active-controlled designs.
2010
Autier et al. Respond to "A Sunbed Epidemic?"
Prognostic factors for cure following treatment of onychomycosis.
Efficacy of amorolfine nail lacquer for the prophylaxis of onychomycosis over 3 years.
A melanoma epidemic in Iceland: possible influence of sunbed use.
2009
New common variants affecting susceptibility to basal cell carcinoma.
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.
Parental origin of sequence variants associated with complex diseases.
2008
Effectiveness and safety of a prevention-of-flare-progression strategy with pimecrolimus cream 1% in the management of paediatric atopic dermatitis.
CDKN2A mutations and melanoma risk in the Icelandic population.
Two newly identified genetic determinants of pigmentation in Europeans.
ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma.
Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits.
2007
A multicentre, randomized, controlled study of the efficacy, safety and cost-effectiveness of a combination therapy with amorolfine nail lacquer and oral terbinafine compared with oral terbinafine alone for the treatment of onychomycosis with matrix involvement.
Onychomycosis: diagnosis and definition of cure.
Genetic determinants of hair, eye and skin pigmentation in Europeans.
2006
Intermittent versus continuous terbinafine in the treatment of toenail onychomycosis: a randomized, double-blind comparison.
Onychomycosis in Icelandic children.
2005
Lifestyle of Nordic people with psoriasis.
Dermatophytes in a swimming pool facility: difference in dermatophyte load in men's and women's dressing rooms.
2004
Dermatophytes in a Swimming Pool Facility: Difference in Dermatophyte Load in Men\textquoterights and Women\textquoterights Dressing Rooms
Self-reported stress reactivity and psoriasis-related stress of Nordic psoriasis sufferers.
Chronic dermatomycoses of the foot as risk factors for acute bacterial cellulitis of the leg: a case-control study.
Blessuð sólin elskar allt [ritstjórnargrein]
Risk factors for malignant melanoma in an Icelandic population sample.
[The darker side of tanning [Editorial].]
Risk factors associated with onychomycosis.
2003
Risk factors for cutaneous malignant melanoma among aircrews and a random sample of the population.
Combination therapy for onychomycosis.
Streptococcal throat infections and exacerbation of chronic plaque psoriasis: a prospective study.
2002
Prognostic factors of mycological cure following treatment of onychomycosis with oral antifungal agents.
Prevalence of onychomycosis in Iceland: a population-based study.
Quality of life in 6497 Nordic patients with psoriasis.
Quality of life and prevalence of arthritis reported by 5,795 members of the Nordic Psoriasis Associations. Data from the Nordic Quality of Life Study.
Long-term effectiveness of treatment with terbinafine vs itraconazole in onychomycosis: a 5-year blinded prospective follow-up study.
2001
Treatment of psoriasis in the Nordic countries: a questionnaire survey from 5739 members of the psoriasis associations data from the Nordic Quality of Life Study.
Frequency of specific cancer types in dermatomyositis and polymyositis: a population-based study.
2000
Incidence of skin cancer in 5356 patients following organ transplantation.
1999
Double blind, randomised study of continuous terbinafine compared with intermittent itraconazole in treatment of toenail onychomycosis. The LION Study Group.
PUVA and cancer risk: the Swedish follow-up study.
L.I.ON. Study: efficacy and tolerability of continuous terbinafine (Lamisil) compared to intermittent itraconazole in the treatment of toenail onychomycosis. Lamisil vs. Itraconazole in Onychomycosis.
Is an epitope on keratin 17 a major target for autoreactive T lymphocytes in psoriasis?
Trioxsalen bath PUVA did not increase the risk of squamous cell skin carcinoma and cutaneous malignant melanoma in a joint analysis of 944 Swedish and Finnish patients with psoriasis.
Onychomycosis in Icelandic swimmers.
1998
Melanocytic naevus or malignant melanoma? A large-scale epidemiological study of diagnostic accuracy.
On the association between vitiligo and malignant melanoma.
1997
Circulating T cells of patients with active psoriasis respond to streptococcal M-peptides sharing sequences with human epidermal keratins.
What is the long term value of multiphasic health screening and the initial judgement of benefit?
1996
Psoriasis treatment: bathing in a thermal lagoon combined with UVB, versus UVB treatment only.
1995
Venous leg ulcers and squamous cell carcinoma: a large-scale epidemiological study.
1994
Cord blood IgE levels are influenced by gestational age but do not predict allergic manifestations in infants.
Risk of lymphoma in patients with dermatitis herpetiformis.
1993
Psoralen photochemotherapy (PUVA) and pregnancy.
PUVA and cancer: a case-control study.
Leg ulcers and squamous cell carcinoma. An epidemiological study and a review of the literature.
1992
Risk of cancer in patients with dermatomyositis or polymyositis. A population-based study.
Skin disease and malignancy. An epidemiological study.
Seborrheic keratoses and cancer.
Comparison of the carcinogenic potential of trioxsalen bath PUVA and oral methoxsalen PUVA. A preliminary report.
1991
PUVA and cancer: a large-scale epidemiological study.
Occurrence of other malignancies in 1973 patients with basal cell carcinoma.
CANEST: a microcomputer program for estimating cancer in a cohort.
Condylomata acuminata and risk of cancer: Authors' reply.
Lichen planus and malignancy. An epidemiologic study of 2071 patients and a review of the literature.
Condylomata acuminata and risk of cancer: an epidemiological study.
PUVA treatment in Sweden.
1990
Chronic urticaria and cancer: an epidemiological study of 1155 patients.
1985
Acute thoracic inlet obstruction in achalasia with adenoid cystic and squamous cell carcinoma.
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