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Berglind Ósk Einarsdóttir - Associate Professor

Berglind Ósk Einarsdóttir

–

Heilbrigðisvísindasvið

Berglind Ósk Einarsdóttir

Associate Professor

Location
Sturlugata 8
Email
boe [at] hi.is

Unit
Radiography & Biomedical Science

Published works

2021

MITF reprograms the extracellular matrix and focal adhesion in melanoma.eLife
Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanismsThe American Journal of Human Genetics

2019

Molecular profiling of driver events and tumor-infiltrating lymphocytes in metastatic uveal melanoma

2018

A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanomaCell Death & Disease
Mutational Signature and Transcriptomic Classification Analyses as the Decisive Diagnostic Tools for a Cancer of Unknown Primary with Neuroendocrine DifferentiationJCO Precision Oncology

2017

BET bromodomain inhibitors synergize with ATR inhibitors in melanoma in melanomaCell death & disease
BRAF V600 inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cellsProceedings of the National Academy of Sciences

2016

Validation and development of MTH1 inhibitors for treatment of cancerAnnals of Oncology
Hypoxia-regulated gene expression explains differences between melanoma cell line-derived xenografts and patient-derived xenograftsOncotarget

2014

Melanoma patient-derived xenografts accurately model the disease and develop fast enough to guide treatment decisionsOncotarget
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP poolNature
Hip fractures and bone mineral density in the elderly - Importance of serum 25-hydroxyvitamin DPLoS ONE

2013

High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancerCancer Medicine

Keywords for Specialisation:

In vivo experiments

Molecular Biology

Circulating tumor DNA