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Ásgeir Haraldsson - Professor

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School of Health Sciences

Ásgeir Haraldsson

Professor

Professor of Paediatrics, University of Iceland Chief and Faculty Chairman, Children's Hospital Iceland

Location
LSH - Hringbraut
Phone
5431000 8245270
Email
asgeirh [at] hi.is

Unit
Faculty of Medicine
Website
http://quickplace.landspitali.is/QuickPlace/ah/PageLibrary00256D8200653D8D.nsf/h_Toc/73c19a9d0a8a02da00256d82006691eb/?OpenDocument

Published works

2024

Influenza vaccination in pregnant women in Iceland 2010-2020 and the burden of influenza in pregnant women and their infantsVaccine
Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effect on recombinationNature Structural and Molecular Biology
Early-onset group B streptococcal infections in five Nordic countries with different prevention policies, 1995 to 2019Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Tonsillectomies are associated with an increased risk of meningococcal carriageInfectious Diseases

2023

Nasopharyngeal competition dynamics are likely to be altered following vaccine introductionMicrobial genomics
Obesity in adolescents does not influence early immune responses to influenza vaccinationInfectious diseases (London, England)
Rannsóknir – þekking – þjónustaLæknablaðið
Adequate immune responses to vaccines after chemotherapy for leukaemia diagnosed in childhoodActa Paediatrica, International Journal of Paediatrics
Long COVID in Icelandic ChildrenThe Pediatric infectious disease journal
Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethalityNature Communications
Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethalityNature Communications
Meningococcal carriage in children and young adultsEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Febrile Children with Pneumonia Have Higher Nasopharyngeal Bacterial Load Than Other Children with FeverPathogens

2022

The cerebrospinal fluid proteome of preterm infants predicts neurodevelopmental outcomeFrontiers in Pediatrics
Simplified antibiotic treatment for paediatric osteoarticular infections achieved good outcomesActa Paediatrica, International Journal of Paediatrics
Nasopharyngeal competition dynamics are likely to be altered following vaccine introduction: bacteriocin prevalence and diversity among Icelandic and Kenyan pneumococcibioRxiv
Clinical and Socioeconomic Burden of Respiratory Syncytial Virus in IcelandPediatric Infectious Disease Journal
Continuous increase of immunoglobulin therapy in IcelandClinical Immunology Communications
Proteomic profiles in cerebrospinal fluid predicted death and disability in term infants with perinatal asphyxia: A pilot studyActa Paediatrica, International Journal of Paediatrics
Continuous increase of immunoglobulin therapy in IcelandClinical Immunology Communications
SARS-CoV-2 Infections in Icelandic ChildrenPediatric Infectious Disease Journal

2021

Children may need higher vancomycin doses to achieve therapeutic levelsActa Paediatrica, International Journal of Paediatrics
HSCT in two brothers with CGD arising from mutations in CYBC1 corrects the defect in neutrophil functionClinical Immunology
The impact and cost-effectiveness of introducing the 10-valent pneumococcal conjugate vaccine into the paediatric immunisation programme in Iceland-A population-based time series analysisPLoS ONE
Burden of rotavirus disease in young children in Iceland – Time to vaccinate?Vaccine
Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibilityPLoS ONE
Low Risk of Central Line-associated Bloodstream Infections in Pediatric Hematology/Oncology PatientsPediatric Infectious Disease Journal
Longitudinal asthma and allergy study showed that childhood symptoms frequently persisted into adulthood.Acta paediatrica (Oslo, Norway : 1992)
Hematopoietic Stem Cell Transplantation Resolves the Immune Deficit Associated with STAT3-Dominant-Negative Hyper-IgE SyndromeJournal of Clinical Immunology
Children may need higher vancomycin doses to achieve therapeutic levels.Acta paediatrica (Oslo, Norway : 1992)
Burden of rotavirus disease in young children in Iceland - Time to vaccinate?Vaccine
No One Will be Safe until Our Children are SafePediatric Infectious Disease Journal
Group B streptococcal infections in infants in IcelandJournal of Medical Microbiology
Decreasing death rates and causes of death in Icelandic children-A longitudinal analysisPLoS ONE
Longitudinal asthma and allergy study showed that childhood symptoms frequently persisted into adulthoodActa Paediatrica, International Journal of Paediatrics

2020

Impact of the 10-valent pneumococcal conjugate vaccine on hospital admissions in children under three years of age in Iceland.Vaccine
Reduction of antimicrobial resistant pneumococci seven years after introduction of pneumococcal vaccine in IcelandPLoS ONE
Impact of the 10-valent pneumococcal conjugate vaccine on hospital admissions in children under three years of age in IcelandVaccine

2019

The Effect of the 10-Valent Pneumococcal Nontypeable Haemophilus influenzae Protein D Conjugate Vaccine on H. influenzae in Healthy Carriers and Middle Ear Infections in Iceland.Journal of Clinical Microbiology
MRSA outbreak in a tertiary neonatal intensive care unit in IcelandInfectious Diseases
Abdominal pain is a common and recurring problem in paediatric emergency departmentsActa Paediatrica, International Journal of Paediatrics
Tardy development of safe medicines for childrenActa Paediatrica, International Journal of Paediatrics
Genomic Analyses of >3,100 Nasopharyngeal Pneumococci Revealed Significant Differences Between Pneumococci Recovered in Four Different Geographical RegionsFrontiers in Microbiology
The Effect of the 10-Valent Pneumococcal Nontypeable Haemophilus influenzae Protein D Conjugate Vaccine on H. influenzae in Healthy Carriers and Middle Ear Infections in IcelandJournal of Clinical Microbiology
Increase in tympanostomy tube placements despite pneumococcal vaccination, a population-based studyActa Paediatrica, International Journal of Paediatrics
Genomic Analyses of >3,100 Nasopharyngeal Pneumococci Revealed Significant Differences Between Pneumococci Recovered in Four Different Geographical Regions.Frontiers in Microbiology
Increase in tympanostomy tube placements despite pneumococcal vaccination, a population-based study.Acta paediatrica

2018

Impact of the 10-valent pneumococcal conjugate vaccine on antimicrobial prescriptions in young children: a whole population study.BMC Infectious Diseases
Reduction in All-Cause Acute Otitis Media in Children <3 Years of Age in Primary Care Following Vaccination with 10-Valent Pneumococcal Haemophilus influenzae Protein-D Conjugate VaccineClinical Infectious Diseases
Vaccination of icelandic children with the 10-valent pneumococcal vaccine leads to a significant herd effect among adults in IcelandJournal of Clinical Microbiology
Vaccine implementation reduces inequityThe Lancet Global Health
A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease.Nature Communications
Effect of Vaccination on Pneumococci Isolated from the Nasopharynx of Healthy Children and the Middle Ear of Children with Otitis Media in Iceland.Journal of Clinical Microbiology
Effect of Vaccination on Pneumococci Isolated from the Nasopharynx of Healthy Children and the Middle Ear of Children with Otitis Media in IcelandJournal of Clinical Microbiology
A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous diseaseNature Communications
Decreased Acute Otitis Media with Treatment Failure after Introduction of the Ten-valent Pneumococcal Haemophilus influenzae Protein D Conjugate VaccinePediatric Infectious Disease Journal
Impact of the 10-valent pneumococcal conjugate vaccine on antimicrobial prescriptions in young children: a whole population studyBMC Infectious Diseases

2017

Comparison of Serotype Prevalence of Pneumococci Isolated from Middle Ear, Lower Respiratory Tract and Invasive Disease Prior to Vaccination in IcelandPLoS ONE
Comparison of Serotype Prevalence of Pneumococci Isolated from Middle Ear, Lower Respiratory Tract and Invasive Disease Prior to Vaccination in Iceland.PLoS ONE
Pneumococcal vaccination: Direct and herd effect on carriage of vaccine types and antibiotic resistance in Icelandic childrenVaccine
Ataxia-telangiectasiaClinical Immunology
Pneumococcal vaccination: Direct and herd effect on carriage of vaccine types and antibiotic resistance in Icelandic children.Vaccine

2016

Correction for van Tonder et al., Genomics Reveals the Worldwide Distribution of Multidrug-Resistant Serotype 6E Pneumococci.Journal of Clinical Microbiology
Breytt viðhorf til sýklalyfjaávísana hjá íslenskum heimilis- og heilsugæslulæknumLæknablaðið
Putatively novel serotypes and the potential for reduced vaccine effectivenessMicrobial genomics
ErratumJournal of Clinical Microbiology
Breytt viðhorf til sýklalyfjaávísana hjá íslenskum heimilis-og heilsugæslulæknumLæknablaðið

2015

Nationwide Incidence of Acquired Central Nervous System Demyelination in Icelandic ChildrenPediatric Neurology
Epidemiology of Primary Immunodeficiency in IcelandJournal of Clinical Immunology
Genomics reveals the worldwide distribution of multidrug-resistant serotype 6E pneumococciJournal of Clinical Microbiology
Public opinion on childhood immunisations in IcelandVaccine
Decreased incidence of respiratory infections in children after vaccination with ten-valent pneumococcal vaccinePediatric Infectious Disease Journal
Decreased postural control in adolescents born with extremely low birth weightExperimental Brain Research
Loss-of-function variants in ATM confer risk of gastric cancerNature Genetics
Low mortality of Staphylococcus aureus bacteremia in icelandic children nationwide study on incidence and outcomeJournal of Pediatric Infectious Diseases

2014

Long-term effects from bacterial meningitis in childhood and adolescence on postural controlPLoS ONE
Epidemiology of Primary Immunodeficiency in IcelandJournal of Clinical Immunology

2013

Behavior and well-being of extremely low birth weight teenagers in IcelandEarly Human Development
Approved and unapproved use of immunoglobulins in IcelandJournal of Allergy and Clinical Immunology
Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversity.The Journal of allergy and clinical immunology
Bacterial meningitis in children in Iceland, 1975-2010Scandinavian Journal of Infectious Diseases
Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversityJournal of Allergy and Clinical Immunology

2012

Kawasaki-sjúkdómur á Íslandi 1996-2005, faraldsfræði og fylgikvillarLæknablaðið
Survival and neurodevelopmental outcome of ELBW children at 5 years of ageActa Paediatrica, International Journal of Paediatrics
Disabilities and health of extremely low-birthweight teenagersActa Paediatrica, International Journal of Paediatrics
A long-term follow-up of allergic diseases in IcelandPediatric Allergy and Immunology
Kawasaki-sjúkdómur á Íslandi 1996-2005, faraldsfræði og fylgikvillarLaeknabladid

2011

Cutaneous granulomas in ataxia telangiectasia and other primary immunodeficienciesDermatology
Beina- og liðasýkingar barna á Íslandi af völdum baktería á tímabilinu 1996-2005Laeknabladid
Increasing incidence of late-onset neonatal invasive group B streptococcal infections in IcelandPediatric Infectious Disease Journal
Increasing incidence of late-onset neonatal invasive group B streptococcal infections in Iceland.Pediatric Infectious Disease Journal
Úlfur, úlfurLaeknabladid

2010

Bacteraemia in children in Iceland 1994-2005Acta Paediatrica, International Journal of Paediatrics
Lifun og dánarorsakir barna sem greindust me∂ krabbamein á Íslandi 1981-2006Laeknabladid
Krabbamein hjá börnum á Íslandi árin 1981-2006Læknablaðið
Bacteraemia in children in Iceland 1994-2005Acta Paediatrica
Lifun og dánarorsakir barna sem greindust með krabbamein á Íslandi 1981-2006Læknablaðið
Krabbamein hjá bönum á Íslandi árin 1981-2006Laeknabladid

2009

Ataxia-telangiectasia patients presenting with hyper-IgM syndromeArchives of Disease in Childhood
Vβ usage and T regulatory cells in children following partial or total thymectomy after open heart surgery in infancyScandinavian Journal of Immunology
An increasing incidence of mastoiditis in children in IcelandScandinavian Journal of Infectious Diseases
Hlaupabóla hjá börnum á Íslandi - Faraldsfræði og fylgikvillarLaeknabladid
Suspected infections in children treated for ALLActa Paediatrica, International Journal of Paediatrics

2008

Blóðsýkingar barna á Íslandi 1994-2005Laeknabladid
Áhrif eðlilegrar fæðingar á súrefnisflutning til fóstursLaeknabladid
Botnlangabólga og botnlangataka hjá bönum á sjúrahúsum í Reykjavík? 1996 og 2006Laeknabladid
Blóðsýkingar barna með æxli og illkynja sjúkdóma 1991-2000Laeknabladid
High prevalence of allergic diseases and sensitization in a low allergen countryActa Paediatrica, International Journal of Paediatrics
Lág þéttni natríums í sermi fyrirburaLaeknabladid

2007

Öndunarerfiðleikar hjá nýburum sem fæðast með valkeisaraskurðiLæknabladid
Stikilbólga hjá börnum á Islandi.Læknabladid
The effects of smoking in pregnancy on factors influencing fetal growthActa Paediatrica, International Journal of Paediatrics

2006

Proteome analysis of vernix caseosaPediatric Research
Samráð með fjarlækningum á ÍslandiLæknabladid
Evidence for extrathymic T cell maturation after thymectomy in infancyClinical and Experimental Immunology

2005

Vernix caseosa as a multi-component defence system based on polypeptides, lipids and their interactionsCellular and Molecular Life Sciences
Meðfædd vélindalokun á Íslandi 1063-2002Læknablaðið
Þekjun bólusetningar barna við Monkey Bay, MalavíLæknablaðið
Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpuraScandinavian Journal of Immunology
Respiratory syncytial virus and other respiratory viruses during the first 3 months of life promote a local T_H2-like responseJournal of Allergy and Clinical Immunology

2004

Congenital cardiac malformations in Iceland from 1990 through 1999Cardiology in the Young
Meðfædd vélindalokun á Íslandi 1963-2002Læknablaðið
The improved survival of experimental animals fed with fish oil is suppressed by a leukotriene inhibitorScandinavian Journal of Immunology
30 antimicrobial components of vernix caseosaPediatric Research
The effect of dietary fish oil on survival after infection with Klebsiella pneumoniae or Streptococcus pneumoniaeScandinavian Journal of Infectious Diseases
The influence of partial or total thymectomy during open heart surgery in infants on the immune function later in lifeClinical and Experimental Immunology

2003

Development of Immunoglobulin a in Infancy and ChildhoodScandinavian Journal of Immunology
Resistance in respiratory tract pathogens and antimicrobial use in Icelandic and Lithuanian childrenScandinavian Journal of Infectious Diseases

2002

Síðkomnar og langvinnar aukaverkanir eftir hvítblæðismeðferð í æskuLæknablaðið
Heilahimnubólga af völdum baktería hjá eins mánaðar til 16 ára gömlum börnum á þremur barnadeildum á Íslandi : samantekt áranna 1973-2000Læknablaðið
Nýgengi og greining meðfæddra hjartagalla á Íslandi 1990-1999Læknablaðið
Increased expression of interleukin-13 but not interleukin-4 in CD4⁺ cells from patients with the hyper-IgE syndromeClinical and Experimental Immunology
Henoch-Schönlein purpura : innlagnir á LSH 1984-2000Læknablaðið
Familial predisposition and cosegregation analysis of adult obstructive sleep apnea and the sudden infant death syndromeAmerican Journal of Respiratory and Critical Care Medicine
Findings in familial haemophagocytic lymphohistiocytosis prior to symptomatic presentationActa Paediatrica, International Journal of Paediatrics
ErratumClinical and Experimental Immunology
Áhrif lýsisríks fæðis á lifun músa eftir sýkingu með Klebsiella pneumoniae eða Streptococcus pneumoniaeLæknablaðið
Verndandi áhrif lýsisríks fæðis eftir sýkingar eru óháð íkomustað bakteríannaLæknablaðið
Greining, árangur meðferðar og síðkomnar aukaverkanir æxla í miðtaugakerfi í æskuLæknablaðið

2001

Immunoglobulin class and subclass concentrations after treatment of childhood leukemiaPediatric Hematology and Oncology
Áhrif lýsisneyslu á bakteríuvöxt in vivoLæknablaðið
Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosisAmerican Journal of Human Genetics

2000

Þegar þú ert orðinn stór [ritstjórnargrein]Læknablaðið
Serum immunoglobulinD in infants and childrenScandinavian Journal of Immunology
Ofnæmi og astmi hjá íslenskum börnumLæknablaðið

1999

Paediatric burns in Iceland. Hospital admissions 1982-1995, a populations based studyBurns
Íslenskur drengur með Lyme-sjúkdóm : sjúkratilfelli og umfjöllunLæknablaðið
Immunoglobulin-secreting cells in cord bloodScandinavian Journal of Immunology

1998

Stofnfrumugræðlingar blóðmyndandi vefsLæknablaðið

1997

Dieatry fish-oil supple-mentation increases survival in mice following Klebsiella Pneumoniae infectionScandinavian Journal of Infectious Diseases
Lýsisneysla eykur lifun músa eftir sýkingu með Klebsiella pneumoniaeLæknablaðið
Dietary fish oil supplementation increases survival in mice following Klebsiella pneumoniae infectionScandinavian Journal of Infectious Diseases
Brunaslys barna á Íslandi : innlagnir á árunum 1982-1995Læknablaðið
T cell subsets and T cell function in cartilage-hair hypoplasiaScandinavian Journal of Immunology

1996

Identification of an unusual Fcγ receptor IIIa (CD16) on natural killer cells in a patient with recurrent infectionsBlood
Kostnaður sparnaðar [ritstjórnargrein]Læknablaðið
CD4 deficiency in myelodysplastic syndrome with monosomy 7European Journal of Pediatrics
Follow-up of leucocyte and reticulocyte counts for the prediction of early graft failure after non-HLA-identical BMT in childrenBone Marrow Transplantation
Busulphan kinetics and limited sampling model in children with leukemia and inherited disordersBone Marrow Transplantation
Risk factors for developing EBV-related B cell lymphoproliferative disorders (BLPD) after non-HLA-identical BMT in childrenBone Marrow Transplantation

1995

Altered immunoglobulin concentrations and light chain ratios in juvenile onset mixed connective tissue diseaseClinical Rheumatology

1994

Light chain ratios and concentrations of immunoglobulins g, a, and m in childhood common acute lymphoblastic leukemiaPediatric Hematology and Oncology
Relationship between patterns of engraftment in peripheral blood and immune reconstitution after allogeneic bone marrow transplantation for (severe) combined immunodeficiencyBlood
Postmortem findings in the Nijmegen breakage syndromeFetal and Pediatric Pathology

1993

Clinical and immunological follow-up in children with hyper-IgD syndromeImmunodeficiency
Immunoglobulin light chain ratios in ataxia telangiectasia and in Nijmegen breakage syndromeImmunologia Clinica
Raised IgA κ/λ ratio in juvenile chronic arthritis [2]Clinical and Experimental Rheumatology
Chimerism and immune reconstitution following allogeneic bone marrow transplantation for severe combined immunodeficiency diseaseImmunodeficiency
Antibody deficiency and isolated growth hormone deficiency in a girl with Mulibrey nanismEuropean Journal of Pediatrics
Light chain ratios and concentrations of serum immunoglobulins in IgA deficiencyImmunologia Clinica
Changes in cell and protein content of cerebrospinal fluid in children with acute lymphoblastic leukaemia after allogeneic bone marrow transplantationBone Marrow Transplantation

1992

Immunoglobulin G, A and M light chain ratio in childrenAnnals of Clinical Biochemistry
Immunological studies in the hyper-immunoglobulin D syndromeJournal of Clinical Immunology
Immunoglobulin G, A, and M Light Chain Ratios in some Humoral Immunological DisordersScandinavian Journal of Immunology
Light chain ratios and concentrations of serum immunoglobulins in children with epilepsyEpilepsy Research
KattarklórskvilliLæknablaðið
New syndromeAmerican Journal of Medical Genetics

1991

Determination of kappa and lambda light chains in serum immunoglobulins G, A and MAnnals of Clinical Biochemistry
Immunological studies in Bloom's syndrome. A follow-up reportAnnales de Genetique
Cartilage hair hypoplasia, metaphyseal chondrodysplasia type McKusickAmerican Journal of Medical Genetics
Griscelli disease with cerebral involvementEuropean Journal of Pediatrics

1990

Prevalence of igm antibodies to nine legionella species in icelandic childrenScandinavian Journal of Infectious Diseases
Kattekrabziekte.Tijdschrift voor Kindergeneeskunde

1989

Half-life of maternal labetalol in a premature infantPharmaceutisch Weekblad Scientific Edition
Orsakir lungnabólgu á Borgarspítalanum 1. desember 1983 til 30. nóvember 1984Læknablaðið
Severe adverse effects of maternal labetalol in a premature infantActa Paediatrica Scandinavica

1988

Legionellosis meðal íslenskra barnaLæknablaðið

1985

Thyrotoxicosis in Iceland 1980–1982Acta Medica Scandinavica

Keywords for Specialisation:

Inflammatory and infectious diseases and vaccine responses

Clinical immunology