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Forsíða

Forsíða

Ásgeir Haraldsson - Professor

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–

School of Health Sciences

Ásgeir Haraldsson

Professor

Professor of Paediatrics, University of Iceland Chief and Faculty Chairman, Children's Hospital Iceland

Location
LSH - Hringbraut
Phone
5431000 8245270
Email
asgeirh [at] hi.is

Unit
Faculty of Medicine
Website
http://quickplace.landspitali.is/QuickPlace/ah/PageLibrary00256D8200653D8D.nsf/h_Toc/73c19a9d0a8a02da00256d82006691eb/?OpenDocument

ORCID site
https://orcid.org/0000-0001-5364-7877
Research portal – Ásgeir Haraldsson
Under construction throughout the autumn semester 2023

Published works

2022

Simplified antibiotic treatment for paediatric osteoarticular infections achieved good outcomesActa Paediatrica
Continuous increase of immunoglobulin therapy in IcelandClinical Immunology Communications
Longitudinal asthma and allergy study showed that childhood symptoms frequently persisted into adulthoodActa Paediatrica

2021

Hematopoietic Stem Cell Transplantation Resolves the Immune Deficit Associated with STAT3-Dominant-Negative Hyper-IgE SyndromeJournal of Clinical Immunology
The impact and cost-effectiveness of introducing the 10-valent pneumococcal conjugate vaccine into the paediatric immunisation programme in Iceland—A population-based time series analysisPLOS ONE
Decreasing death rates and causes of death in Icelandic children—A longitudinal analysisPLOS ONE
Group B streptococcal infections in infants in Iceland: clinical and microbiological factorsJournal of Medical Microbiology

2020

Reduction of antimicrobial resistant pneumococci seven years after introduction of pneumococcal vaccine in IcelandPLoS ONE
Impact of the 10-valent pneumococcal conjugate vaccine on hospital admissions in children under three years of age in IcelandVaccine

2019

Increase in tympanostomy tube placements despite pneumococcal vaccination, a population‐based studyActa Paediatrica
Tardy development of safe medicines for children: a Nordic network offers new platform to reduce this inequityActa Paediatrica, International Journal of Paediatrics
The Effect of the 10-Valent Pneumococcal NontypeableHaemophilus influenzaeProtein D Conjugate Vaccine onH. influenzaein Healthy Carriers and Middle Ear Infections in IcelandJournal of Clinical Microbiology
MRSA outbreak in a tertiary neonatal intensive care unit in IcelandInfectious Diseases
Genomic analyses of >3,100 nasopharyngeal pneumococci revealed significant differences between pneumococci recovered in four different geographical regionsFrontiers in Microbiology
The effect of the 10-valent pneumococcal nontypeable haemophilus influenzae protein D conjugate vaccine on H. Influenzae in healthy carriers and middle ear infections in IcelandJournal of Clinical Microbiology
Abdominal pain is a common and recurring problem in paediatric emergency departmentsActa Paediatrica

2018

Vaccine implementation reduces inequityThe Lancet Global Health
Vaccine implementation reduces inequityThe Lancet Global Health
Impact of the 10-valent pneumococcal conjugate vaccine on antimicrobial prescriptions in young children: A whole population studyBMC Infectious Diseases
Reduction in All-Cause Acute Otitis Media in Children <3 Years of Age in Primary Care Following Vaccination with 10-Valent Pneumococcal Haemophilus influenzae Protein-D Conjugate Vaccine: A Whole-Population StudyClinical Infectious Diseases
Decreased Acute Otitis Media With Treatment Failure After Introduction of the Ten-valent Pneumococcal Haemophilus influenzae Protein D Conjugate VaccinePediatric Infectious Disease Journal
Effect of vaccination on pneumococci isolated from the nasopharynx of healthy children and the middle ear of children with otitis media in IcelandJournal of Clinical Microbiology
A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous diseaseNature Communications
Decreased Acute Otitis Media with Treatment Failure after Introduction of the Ten-valent Pneumococcal Haemophilus influenzae Protein D Conjugate VaccinePediatric Infectious Disease Journal
Vaccination of icelandic children with the 10-valent pneumococcal vaccine leads to a significant herd effect among adults in IcelandJournal of Clinical Microbiology

2017

Ataxia-telangiectasia: Immunodeficiency and survivalClinical Immunology
Pneumococcal vaccination: Direct and herd effect on carriage of vaccine types and antibiotic resistance in Icelandic childrenVaccine
Comparison of serotype prevalence of pneumococci isolated from middle ear, lower respiratory tract and invasive disease prior to vaccination in IcelandPLoS ONE

2016

Erratum: Genomics Reveals the Worldwide Distribution of Multidrug-Resistant Serotype 6E Pneumococci (Journal of Clinical Microbiology (2015) 53:7 (2271-2285))Journal of Clinical Microbiology
Putatively novel serotypes and the potential for reduced vaccine effectiveness: capsular locus diversity revealed among 5405 pneumococcal genomesMicrobial genomics
Change in attitude towards antibiotic prescriptions among Icelandic general practitioners,Breytt VIohorf til sýklalyfjaáVÍsana hjá íslenskum heimilis-og heilsugæslulæknumLaeknabladid

2015

Genomics reveals the worldwide distribution of multidrug-resistant serotype 6E pneumococciJournal of Clinical Microbiology
Low mortality of Staphylococcus aureus bacteremia in icelandic children nationwide study on incidence and outcomeJournal of Pediatric Infectious Diseases
Loss-of-function variants in ATM confer risk of gastric cancerNature Genetics
Decreased postural control in adolescents born with extremely low birth weightExperimental Brain Research
Decreased incidence of respiratory infections in children after vaccination with ten-valent pneumococcal vaccinePediatric Infectious Disease Journal
Nationwide Incidence of Acquired Central Nervous System Demyelination in Icelandic ChildrenPediatric Neurology
Public opinion on childhood immunisations in IcelandVaccine
Low Mortality of Staphylococcus aureus Bacteremia in Icelandic ChildrenPediatric Infectious Disease Journal
Decreased Incidence of Respiratory Infections in Children After Vaccination with Ten-valent Pneumococcal VaccinePediatric Infectious Disease Journal
Epidemiology of Primary Immunodeficiency in IcelandJournal of Clinical Immunology

2014

Long-term effects from bacterial meningitis in childhood and adolescence on postural controlPLoS ONE

2013

Bacterial meningitis in children in Iceland, 1975-2010: A nationwide epidemiological studyScandinavian Journal of Infectious Diseases
Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversityJournal of Allergy and Clinical Immunology
Approved and unapproved use of immunoglobulins in IcelandJournal of Allergy and Clinical Immunology
Behavior and well-being of extremely low birth weight teenagers in IcelandEarly Human Development

2012

Survival and neurodevelopmental outcome of ELBW children at 5 years of age: Comparison of two cohorts born 10 years apartActa Paediatrica, International Journal of Paediatrics
Kawasaki disease in Iceland 1996-2005, epidemiology and complications,Kawasaki-sjúkdómur á Íslandi 1996-2005, faraldsfræoi og fylgikvillarLaeknabladid
Disabilities and health of extremely low-birthweight teenagers: A population-based studyActa Paediatrica, International Journal of Paediatrics
A long-term follow-up of allergic diseases in IcelandPediatric Allergy and Immunology

2011

Cry wolf,Úlfur, úlfurLaeknabladid
Cutaneous granulomas in ataxia telangiectasia and other primary immunodeficiencies: Reflection of inappropriate immune regulation?Dermatology
Increasing incidence of late-onset neonatal invasive group B streptococcal infections in IcelandPediatric Infectious Disease Journal
Bactrial osteomyelitis and arthritis in Icelandic children 1996-2005,Beina- og lioasýkingar barna á Íslandi af völdum baktería á tímabilinu 1996-2005Laeknabladid

2010

Childhood cancer in Iceland 1981-2006,Krabbamein hjá bönum á Íslandi árin 1981-2006Laeknabladid
Survival and causes of death in children diagnosed with cancer in Iceland 1981-2006,Lifun og dánarorsakir barna sem greindust me∂ krabbamein á Íslandi 1981-2006Laeknabladid
Bacteraemia in children in Iceland 1994-2005Acta Paediatrica, International Journal of Paediatrics

2009

Varicella in Icelandic children - Epidemiology and complications,Hlaupabóla hjá börnum á Íslandi - Faraldsfraeoi og fylgikvillarLaeknabladid
Suspected infections in children treated for ALLActa Paediatrica, International Journal of Paediatrics
Vβ usage and T regulatory cells in children following partial or total thymectomy after open heart surgery in infancyScandinavian Journal of Immunology
An increasing incidence of mastoiditis in children in IcelandScandinavian Journal of Infectious Diseases
Ataxia-telangiectasia patients presenting with hyper-IgM syndromeArchives of Disease in Childhood

2008

Bacteraemia in children in Iceland 1994-2005,Blódsýkingar barna á Íslandi 1994-2005Laeknabladid
Bacteremia in children with tumors or malignant diseases 1991-2000,Blódsýkingar barna med æxli og illkynja sjúkdóma 1991-2000Laeknabladid
The effects of normal vaginal delivery on oxygen transport to the fetus,Áhrif eǒlilegrar fæǒingar á súrefnisflutning til fóstursLaeknabladid
High prevalence of allergic diseases and sensitization in a low allergen countryActa Paediatrica, International Journal of Paediatrics
Hyponatremia in very low birth weight infants,Lág péttni natríums í sermi fyrirburaLaeknabladid
Appendicitis and appendectomy in Children in Reykjavik Hospitals in 1996 and 2006,Botnlangabóga og botnlangataka hjá bönum á sjúrahúsum í Reykjavík? 1996 og 2006Laeknabladid

2007

Mastoiditis in children in Iceland,Stikilbólga hjá börnum á Islandi.Læknabladid
The effects of smoking in pregnancy on factors influencing fetal growthActa Paediatrica, International Journal of Paediatrics
Respiratory dysfunction in infants born by elective cesarean section without labor,Ondunarördugleikar hjá nýburum sem faedast med valkeisaraskurdi.Læknabladid
Findings in familial haemophagocytic lymphohistiocytosis prior to symptomatic presentationActa Paediatrica

2006

Telemedicine consultations in Iceland,Samráeth meeth fjarlaekningum á Islandi.Læknabladid
Evidence for extrathymic T cell maturation after thymectomy in infancyClinical and Experimental Immunology
Proteome analysis of vernix caseosaPediatric Research

2005

Respiratory syncytial virus and other respiratory viruses during the first 3 months of life promote a local TH2-like responseJournal of Allergy and Clinical Immunology
Vernix caseosa as a multi-component defence system based on polypeptides, lipids and their interactionsCellular and Molecular Life Sciences
Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpuraScandinavian Journal of Immunology
Congenital cardiac malformations in Iceland from 1990 through 1999Cardiology in the Young

2004

30 antimicrobial components of vernix caseosaPediatric Research
The improved survival of experimental animals fed with fish oil is suppressed by a leukotriene inhibitorScandinavian Journal of Immunology
The effect of dietary fish oil on survival after infection with Klebsiella pneumoniae or Streptococcus pneumoniaeScandinavian Journal of Infectious Diseases
Congenital cardiac malformations in Iceland from 1990 through 1999Cardiology in the Young
The influence of partial or total thymectomy during open heart surgery in infants on the immune function later in lifeClinical and Experimental Immunology

2003

Resistance in respiratory tract pathogens and antimicrobial use in Icelandic and Lithuanian childrenScandinavian Journal of Infectious Diseases
Development of Immunoglobulin a in Infancy and ChildhoodScandinavian Journal of Immunology

2002

Familial predisposition and cosegregation analysis of adult obstructive sleep apnea and the sudden infant death syndromeAmerican Journal of Respiratory and Critical Care Medicine
Findings in familial haemophagocytic lymphohistiocytosis prior to symptomatic presentationActa Paediatrica, International Journal of Paediatrics
Increased expression of interleukin-13 but not interleukin-4 in CD4⁺ cells from patients with the hyper-IgE syndromeClinical and Experimental Immunology
Erratum: Increased expression of interleukin-13 but not interleukin-4 in CD4+ cells from patients with the hyper-IgE syndrome (Clinical and Experimental Immunology (2002) 128 (532-537))Clinical and Experimental Immunology

2001

Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosisAmerican Journal of Human Genetics
Immunoglobulin class and subclass concentrations after treatment of childhood leukemiaPediatric Hematology and Oncology

2000

Serum immunoglobulinD in infants and childrenScandinavian Journal of Immunology

1999

Paediatric burns in Iceland.Burns
Immunoglobulin-secreting cells in cord blood: Effects of Epstein-Barr virus and interleukin-4Scandinavian Journal of Immunology
Paediatric burns in Iceland. Hospital admissions 1982-1995, a populations based studyBurns
Development of IgA System in InfancyPediatric Research

1997

T cell subsets and T cell function in cartilage-hair hypoplasiaScandinavian Journal of Immunology
Dietary fish oil supplementation increases survival in mice following Klebsiella pneumoniae infectionScandinavian Journal of Infectious Diseases

1996

Follow-up of leucocyte and reticulocyte counts for the prediction of early graft failure after non-HLA-identical BMT in childrenBone Marrow Transplantation
CD4 deficiency in myelodysplastic syndrome with monosomy 7European Journal of Pediatrics
Identification of an unusual Fcγ receptor IIIa (CD16) on natural killer cells in a patient with recurrent infectionsBlood
Busulphan kinetics and limited sampling model in children with leukemia and inherited disordersBone Marrow Transplantation
CD4 deficiency in myelodysplastic syndrome with monosomy 7European Journal of Pediatrics
CD4 deficiency in myelodysplastic syndrome with monosomy 7European Journal of Pediatrics
Risk factors for developing EBV-related B cell lymphoproliferative disorders (BLPD) after non-HLA-identical BMT in childrenBone Marrow Transplantation

1995

Altered immunoglobulin concentrations and light chain ratios in juvenile onset mixed connective tissue diseaseClinical Rheumatology
Altered immunoglobulin concentrations and light chain ratios in juvenile onset mixed connective tissue diseaseClinical Rheumatology

1994

Relationship between patterns of engraftment in peripheral blood and immune reconstitution after allogeneic bone marrow transplantation for (severe) combined immunodeficiencyBlood
Postmortem findings in the Nijmegen breakage syndromeFetal and Pediatric Pathology
Light chain ratios and concentrations of immunoglobulins g, a, and m in childhood common acute lymphoblastic leukemiaPediatric Hematology and Oncology

1993

Clinical and immunological follow-up in children with hyper-IgD syndromeImmunodeficiency
Chimerism and immune reconstitution following allogeneic bone marrow transplantation for severe combined immunodeficiency diseaseImmunodeficiency
Light chain ratios and concentrations of serum immunoglobulins in IgA deficiencyImmunologia Clinica
Raised IgA κ/λ ratio in juvenile chronic arthritis [2]Clinical and Experimental Rheumatology
Antibody deficiency and isolated growth hormone deficiency in a girl with Mulibrey nanismEuropean Journal of Pediatrics
Changes in cell and protein content of cerebrospinal fluid in children with acute lymphoblastic leukaemia after allogeneic bone marrow transplantationBone Marrow Transplantation
Immunoglobulin light chain ratios in ataxia telangiectasia and in Nijmegen breakage syndromeImmunologia Clinica
Antibody deficiency and isolated growth hormone deficiency in a girl with Mulibrey nanismEuropean Journal of Pediatrics

1992

Immunological studies in the hyper-immunoglobulin D syndromeJournal of Clinical Immunology
Immunological studies in the hyper-immunoglobulin D syndromeJournal of Clinical Immunology
Immunoglobulin G, A, and M Light Chain Ratios in some Humoral Immunological DisordersScandinavian Journal of Immunology
Light chain ratios and concentrations of serum immunoglobulins in children with epilepsyEpilepsy Research
New syndrome: Absent thumb, immune disorder, and congenital anemia presenting with hydrops fetalisAmerican Journal of Medical Genetics
Immunoglobulin G, A and M light chain ratio in childrenAnnals of Clinical Biochemistry

1991

Griscelli disease with cerebral involvementEuropean Journal of Pediatrics
Cartilage hair hypoplasia, metaphyseal chondrodysplasia type McKusick: Description of seven patients and review of the literatureAmerican Journal of Medical Genetics
Immunological studies in Bloom's syndrome. A follow-up reportAnnales de Genetique
Determination of kappa and lambda light chains in serum immunoglobulins G, A and MAnnals of Clinical Biochemistry
Griscelli disease with cerebral involvementEuropean Journal of Pediatrics

1990

Cat-scratch disease,Kattekrabziekte.Tijdschrift voor kindergeneeskunde
Prevalence of igm antibodies to nine legionella species in icelandic childrenScandinavian Journal of Infectious Diseases

1989

Half-life of maternal labetalol in a premature infantPharmaceutisch Weekblad Scientific Edition
Severe adverse effects of maternal labetalol in a premature infantActa Paediatrica Scandinavica
Half-life of maternal labetalol in a premature infantPharmaceutisch Weekblad Scientific Edition

1985

Thyrotoxicosis in Iceland 1980–1982: An Epidemiological SurveyActa Medica Scandinavica

Keywords for Specialisation:

Inflammatory and infectious diseases and vaccine responses

Clinical immunology