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Forsíða

Sigurður Ingvarsson - Professor

Sigurður Ingvarsson

–

School of Health Sciences

Sigurður Ingvarsson

Professor

Professor and director

Location
Tilraunastöð HÍ. í meinafræði - Keldum
Phone
8943235 8943235
Email
siguring [at] hi.is

Unit
Faculty of Medicine
Website
https://keldur.is/is

ORCID site
https://orcid.org/0000-0003-4125-1714
Research portal – Sigurður Ingvarsson
Under construction throughout the autumn semester 2023

Published works

2023

Vísindadagur Keldna 2023Institute for Experimental Pathology, University of Iceland at Keldur
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2022Institute for Experimental Pathology, University of Iceland at Keldur

2022

Tilraunastöð Háskóla Íslands í meinafræði að KeldumÍsland - Atvinnuhættir og menning

2021

Hversu sýnilegt er “Icelandic Agricultural Sciences” í alþjóðlegum vefsetrum? Líffræðiráðstefnan 2021
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2021Institute for Experimental Pathology, University of Iceland at Keldur

2020

Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2020Institute for Experimental Pathology, University of Iceland at Keldur

2019

Vefsetursgreining á „Icelandic Agricultural Sciences“Líffræðiráðstefnan 2019 – Líffræðifélag Íslands. Reykjavík 17.-19. október 2019
Hif umritunarþáttur og Nóbelsverðlaunin í líf- og læknisfræði árið 2019
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2019Institute for Experimental Pathology, University of Iceland at Keldur

2018

Keldur - Leiðandi stofnun í rannsóknum á dýrasjúkdómumInstitute for Experimental Pathology, University of Iceland at Keldur
Vísindadagur á Keldum á sjötíu ára starfsafmæliBændablaðið
Vísindadagur á Keldum - Keldur 70 ára, 1948-2018Institute for Experimental Pathology, University of Iceland at Keldur
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2018Institute for Experimental Pathology, University of Iceland at Keldur
Hvað hefur vísindamaðurinn Sigurður Ingvarsson rannsakað?Vísindavefurinn
Smitandi æxlisfrumur í ljósi þróunar

2017

Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2017Institute for Experimental Pathology, University of Iceland at Keldur
Genomic, proteomic and clinicopathological events in carriers of the Icelandic BRCA2 999del5 founder mutation3rd World Congress on Cancer and Prevention Methods - "Scientific Future Group", Barcelona

2016

Epigenetic control of MLH1 expression by promoter variant and methylation spreading from Alu repeatsThe 18th Nordic Congress in Human Genetics, Reykjavik
Vísindadagur á Keldum 2016Institute for Experimental Pathology, University of Iceland at Keldur
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2016Institute for Experimental Pathology, University of Iceland at Keldur

2015

MicroRNA451 bælir æxlisvöxt með því að minnka tjáningu IL6R gensIcelandic Medical Journal
DNA viðgerðir og Nóbelsverðlaunin í efnafræði árið 2015Institute for Experimental Pathology, University of Iceland at Keldur
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2015Institute for Experimental Pathology, University of Iceland at Keldur

2014

EditorialIcelandic Agricultural Sciences
Icelandic Agricultural Sciences. Vel sýnilegt í alþjóðlega viðurkenndum vefsetrumLandsýn - Vísindaþing Landbúnaðarins
Vísindadagur á Keldum 2014Institute for Experimental Pathology, University of Iceland at Keldur
The IL6R Expression is Downregulated by miR-451 in Tumour ProgressionScandinavian Journal of Immunology
Greining á ritverkum Keldna 2004-2013Institute for Experimental Pathology, University of Iceland at Keldur
MicroRNA-451 suppresses tumor cell growth by down-regulating IL6R gene expressionCancer Epidemiology
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2014
Úttekt á sýnileika vísindatímaritsins „Icelandic Agricultural Sciences“ í alþjóðlegum vefsetrumVísindadagur Keldna 2014
Hversu sýnilegt er “Icelandic Agricultural Sciences” í alþjóðlegum vefsetrum?Skrína — rit um auðlinda-, landbúnaðar- og umhverfisvísindi
THE GENETIC LANDSCAPE OF FAMILIAL BREAST CANCER IN ICELANDAnticancer Research
Virkni Hif-umritunarþáttar er stýrt með prótein-niðurbrotiVísindadagur Keldna 2014

2013

Greining á tímaritinu „Icelandic Agricultural Sciences“ skv. alþjóðlega viðurkenndum vefsetrumLíffræðiráðstefnan 2013
Hlutverk Limd1 í stjórnunarferli Hif1 umritunarþáttarLíffræðiráðstefnan 2013
Rannsóknir eru undirstaða þróunar og hagsældar í landbúnaðiBændablaðið
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2013Institute for Experimental Pathology, University of Iceland at Keldur
Anders Jahre-verðlaunin veitt fyrir rannsóknir á sykursýkiIcelandic Medical Journal
EditorialIcelandic Agricultural Sciences
In memoriam Bjorn Sigurdsson born 100 years agoIcelandic Agricultural Sciences
Icelandic Agricultural Sciences er viðurkennt ISI-vísindaritLandsýn – vísindaþing landbúnaðarins 2013

2012

Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2012Institute for Experimental Pathology, University of Iceland at Keldur
Greining á ISI-ritverkum Tilraunastöðvar Háskóla Íslands í meinafræði að Keldum frá árunum 2002-2011Vísindadagur Keldna 2012
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activityNature Cell Biology
Meinafræði að Keldum í minningu Guðmundar GeorgssonarInstitute for Experimental Pathology, University of Iceland at Keldur
Icelandic Agricultural Sciences. Vinsæll vettvangur til að birta niðurstöður íslenskra skógfræðirannsóknaFagráðstefna Skógræktar
Demethylation of the region around exon 2 of MLH1 gene in gastrointestinal cancerAnticancer Research
Icelandic Agricultural Sciences. Vinsæll vettvangur til að birta niðurstöður íslenskra skógfræðirannsóknaFagráðstefna Skógræktar
Brautryðjandi í sykursýkisrannsóknum fær Jahre-verðlauninIcelandic Medical Journal
Rannsóknir og þjónusta á Keldum í þágu dýraheilbrigðisBændablaðið
Universal RNA editing in a human liver at the fetal stageOpen Journal of Genetics
Hif, lykilumritunarþáttur í efnaskiptum og æðamyndunInstitute for Experimental Pathology, University of Iceland at Keldur
Universal RNA editing in a human liver at the fetal stageOpen Journal of Genetics
Vísindadagur á Keldum 2012Institute for Experimental Pathology, University of Iceland at Keldur
Icelandic Agricultural Sciences (IAS), viðurkennt ISI-vísindaritVísindadagur á Keldum 2012
Demethylation of the region around exon 2 of MLH1 gene in gastrointestinal cancer.
Demethylation of the Region around Exon 2 of MLH1 Gene in Gastrointestinal CancerAnticancer Research

2011

Anders Jahre-verðlauninLaeknabladid
Stökkbreytingar sem leiða til æxlisvaxtar: Náttúrulegt val?Læknadagar 2011
Metýlun stjórnraðar og tjáning Lactoferrins í lungnaæxlum.Vísindi á vordögum 2011
Spreading of Alu Methylation to the Promoter of the MLH1 Gene in Gastrointestinal CancerPlos One
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2011Institute for Experimental Pathology, University of Iceland at Keldur
Icelandic Agricultural Sciences er nú viðurkennt ISI-tímaritLíffræðiráðstefnan 2011
Ávarp - Lofsvert Lagnaverk 2009Fréttabréf Lagnafélags Íslands
Icelandic Agricultural Sciences er nú viðurkennt ISI-vísindaritFræðaþing Landbúnaðarins
Quantitative Analysis of miRNA Expression in Seven Human Foetal and Adult OrgansPlos One
Spreading of alu methylation to the promoter of the mlh1 gene in gastrointestinal cancerPLoS ONE
Quantitative analysis of miRNa expression in seven human foetal and adult organsPLoS ONE

2010

Þroski, vöxtur og starfsemi vessaæða í heilbrigðum og sjúkum vefInstitute for Experimental Pathology, University of Iceland at Keldur
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2010Institute for Experimental Pathology, University of Iceland at Keldur
Quantitative analysis of miRNA expression in several developmental stages of human liversHepatology Research
The MLH1-93 promoter variant influences gene expressionCancer Epidemiology
Tjáning á LIMD1 og HIF1-alpha próteinum í nýrnaæxlumVísindi á vordögum
Vísindadagur á Keldum 2010Institute for Experimental Pathology, University of Iceland at Keldur
Icelandic Agricultural SciencesVísindadagur á Keldum 2010

2009

Nóbelsverðlaunin í lífeðlis- og læknisfræði 2009: Litningaendar og lífhvatinn telómeraseTímarit um raunvísindi og stærðfræði
Nóbelsverðlaunin í líf- og læknisfræði 2009: Litningaendar og telómerasiInstitute for Experimental Pathology, University of Iceland at Keldur
Lactoferrin prótein tjáning er minnkuð í lungnaæxlumLíffræðiráðstefnan 2009
The Nobel Prize in Physiology or Medicine 2009; How chromosomes are protected by telomeres and the enzyme telomeraseChemistry Seminars - University of Iceland
Identification of miRNAs in a liver of a human fetus by a modified methodPLoS ONE
Identification of miRNAs in a Liver of a Human Fetus by a Modified MethodPlos One
Frumusækni mæði-visnuveiruXIV Vísindaráðstefna Háskóla Íslands
Hvernig litningaendar eru varðir af litningaendum og lífhvatinn telómerasiFræðslufundur Erfða- og Sameindalæknisfræðideildar Landspítala Háskólasjúkrahúss
The sixty year anniversary of the Institute for Experimental Pathology, University of Iceland at Keldur PrefaceIcelandic Agricultural Sciences
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2009Institute for Experimental Pathology, University of Iceland at Keldur
Lactoferrin prótein tjáning er minnkuð í lungnaæxlumVísindi á vordögum

2008

Genomic instability in breast cancerThe 1st international conference on drug design and discovery
Genomic instability in breast cancerFrontiers in Breast Cancer Research
Minnkuð lactotransferrin tjáning í lungnaæxlumVísindi á vordögum 2008
60 ára starfsafmæli Tilraunastöðvar Háskóla Íslands í meinafræði að KeldumBændablaðið
International Conference on Fish Diseases and Fish Immunology. In Celebration of the 60th Anniversary of the Institute for Experimental Pathology, University of Iceland, KeldurInstitute for Experimental Pathology, University of Iceland at Keldur
Ársskýrsla Tilraunatöðvar Háskóla Íslands í meinafræði að Keldum - 2008Institute for Experimental Pathology, University of Iceland at Keldur
Icelandic Agricultural Sciences: Alþjóðlegt tímarit á ensku fyrir vísindagreinar í lífvísindumFræðaþing Landbúnaðarins
In vitro analysis of expression vectors for DNA vaccination of horses: The effect of a Kozak sequenceActa Veterinaria Scandinavica
Population Approach in Breast Cancer Research Based on Integration of Genetic, Clinicopathological and Genealogical CluesThe Open Cancer Journal
CELLULAR BIOLOGY OF BREAST CANCER, FOCUSING ON GENOMIC AND CLINICOPATHOLOGICAL EVENTS IN CARRIERS OF A BRCA2 FOUNDER MUTATIONAnticancer Research
In vitro analysis of expression vectors for DNA vaccination of horses: the effect of a Kozak sequenceActa Veterinaria Scandinavica

2007

A29T fjölbreytileiki í LTF er algengur í lungnaæxlumVísindi á vordögum 2007
Duplicated sequence motif in the long terminal repeat of maedi-visna viras extends cell tropism and is associated with neurovirulenceJournal of Virology
Duplicated sequence motif in the long terminal repeat of maedi-visna virus extends cell tropism and is associated with neurovirulenceJournal of Virology
Taugasækni mæði-visnuveirunnarÞrettánda ráðstefnan um rannsóknir í líf- og heilbrigðisvísindum í Háskóla Íslands
Ársskýrsla 2007 - Tilraunastöð Háskóla Íslands í meinafræði að KeldumInstitute for Experimental Pathology, University of Iceland at Keldur
In vitro analysis of expression vectors for DNA vaccination in horses3rd International Workshop on Allergic Diseases of the horse
Stökkbreytingaleit í LIMD1 og LTF genum á 3p21.3 í æxlumÞrettánda ráðstefnan um rannsóknir í líf- og heilbrigðisvísindum í Háskóla Íslands

2006

Ársskýrsla 2006 - Tilraunastöð Háskóla Íslands í meinafræði að KeldumInstitute for Experimental Pathology, University of Iceland at Keldur
Vísindadagur á Keldum 2006Institute for Experimental Pathology, University of Iceland at Keldur
Taugasækni mæði-visnuveirunnarVísindadagur á Keldum
Sameindalíffræði RNA inngripsUniversity of Iceland
Nóbelsverðlaun í lífeðlis- eða læknisfræði 2006 – RNA íhlutunInstitute for Experimental Pathology, University of Iceland at Keldur
Leit að stökkbreytingum í LIMD1 og LTF genum á CER1 svæði á mannalitningi 3p21.3 í 10 mismunandi Vísindadagur á Keldum 2006
Hvað er RNA-inngrip?
Genomic instability and breast cancer progressionCancer Genomics and Proteomics
Erfðagreyping og sjúkdómsmyndInstitute for Experimental Pathology, University of Iceland at Keldur

2005

Icelandic Agricultural Sciences - Alþjóðlegt tímarit fyrir vísindagreinar í lífvísindumFræðaþing Landbúnaðarins
Deletions at the chromosome 3 common eliminated region 1 on 3p21.3 in human breast tumors.
Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to HerceptinOncogene
Deletions at the chromosome 3 common eliminated region 1 on 3p21.3 in human breast tumorsBreast Cancer Research
Tumor suppressor genes on human chromosome 3 and cancer pathogenesisCancer Genomics and Proteomics
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2005Institute for Experimental Pathology, University of Iceland at Keldur
[Uniparental disomy of chromosome 11 in a patient with Beckwith-Wiedemann syndrome. First reported case in Iceland].
Breytingar á litningi 3 og framvinda æxlisvaxtar í nagdýrum og mönnum
Ralt er æxlisbæliprótein sem hefur áhrif á lyfjanæmiInstitute for Experimental Pathology, University of Iceland at Keldur
Uniparental disomy of chromosome 11 in a patient with Beckwith-Wiedemann syndrome. First reported case in Iceland | Tvístæða litnings nr. 11 frá föður hjá sjúklingi með Beckwith-Wiedemann heilkenni. Fyrsta greining á Íslandi--Sjúkratilfelli.Læknabladid
Tumour suppressor genes at chromosome 3 and cancer pathogenesis2005 World DNA and Genome Day

2004

Genetics of breast cancer.
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2004Institute for Experimental Pathology, University of Iceland at Keldur
Ósamfelldar úrfellingar á C3CER1 litningasvæði eru algengar í æxlum frá tíu mismunandi vefjumAfmælisráðstefna Líffræðifélags Íslands og Líffræðistofnunar Háskólans: Líffræði - vaxandi vísindi
Interstitial deletions including chromosome 3 common eliminated region I (C3CERI) prevail in human solid tumors from 10 different tissuesGenes Chromosomes & Cancer
Genetics of breast cancerDrugs of Today
Vísindadagur á Keldum 2004Institute for Experimental Pathology, University of Iceland at Keldur
Nóbelsverðlaunin í efnafræði 2004 – Ubiquitin miðlað próteinniðurbrotRAUST - Tímarit um raunvísindi og stærðfræði
Taugasækni mæði-visnuveiruAfmælisráðstefna Líffræðifélags Íslands og Líffræðistofnunar Háskólans: Líffræði - vaxandi vísindi
Duplicated sequence motif in the long terminal repeat of maedi-visna virus extends cell tropism and is associated with neurovirulenceMolecular Mechanism of HIV Pathogenesis (X7). Keystone Symposia
Taugasækni mæði-visnuveirunnarVísindadagur á Keldum 2004
ALTERATIONS AT CHROMOSOME 3 AND CANCER PATHOGENESISAnticancer Research

2003

Germline mutations in DNA repair and cell cycle checkpoint genes: consequential somatic gene alterations and genome instability.
Erfðabreytileiki íslenska hestastofnsinsXI. ráðstefnan um rannsóknir í læknadeild, tannlæknadeild og lyfjafræðideild Háskóla Íslands
Rannsóknir á E-cadherini, beta-catenini og FHIT í magakrabbameinumXI. ráðstefnan um rannsóknir í læknadeild, tannlæknadeild og lyfjafræðideild Háskóla Íslands
Tap á arfblendni innan C3CER1 svæðis á litningi 3p21.3 í æxlum frá tíu mismunandi líffærumXI. ráðstefnan um rannsóknir í læknadeild, tannlæknadeild og lyfjafræðideild Háskóla Íslands
Molecular Genetics of Breast CancerInternational Journal of Human Genetics

2002

Epidemiology — laboratoryEuropean Journal of Cancer
Loss of heterozygosity at the FHIT gene in different solid human tumours and its association with survival in colorectal cancer patientsAnticancer Research
High frequency of LOH, MSI and abnormal expression of FHIT in gastric cancerEuropean Journal of Cancer
Loss of heterozygosity at the FHIT gene in different solid human tumours and its association with survival in colorectal cancer patients.
Mutation analysis of the CHK2 gene in breast carcinoma and other cancersBreast Cancer Research
High frequency of LOH, MSI and abnormal expression of FHIT in gastric cancerEuropean Journal of Cancer
Loss of heterozygosity at the FHIT gene in different solid human tumours and its association with survival in colorectal cancer patientsAnticancer Research
Mutation analysis of the CHK2 gene in breast carcinoma and other cancersBreast Cancer Research
Pattern of FHIT LOH in different solid human tumors; association with survival in colorectal cancer patientsCancer Epidemiology Biomarkers & Prevention
Vísindadagur á Keldum 2002Institute for Experimental Pathology, University of Iceland at Keldur

2001

Alterations of the FHIT gene in breast cancer: Association with tumor progression and patient survivalCancer Detection and Prevention
Alterations of the FHIT gene in breast cancer: association with tumor progression and patient survival.
Breast cancer: introductionSeminars in Cancer Biology
Alterations of E-cadherin and beta-catenin in gastric cancerBmc Cancer
Alterations of E-cadherin and beta-catenin in gastric cancer.BMC cancer [electronic resource]
Similar regions of human chromosome 3 are eliminated from or retained in human/human and human/mouse microcell hybrids during tumor growth in severe combined immunodeficient (SCID) miceProceedings of the National Academy of Sciences of the United States of America
FHIT alterations in breast cancerSeminars in Cancer Biology
Alterations of the FHIT gene in breast cancer: association with tumor progression and patient survival.Cancer Detection and Prevention

2000

Molecular biology of breast cancer.Oncology reports
Population studies and validation of paternity determinations by six microsatellite lociJournal of Forensic Sciences
The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequencesInternational Journal of Oncology
Molecular biology of breast cancer.
Altered expression of E-cadherin in breast cancer: patterns, mechanisms and clinical significanceEuropean Journal of Cancer
Analysis of the fragile histidine triad (FHIT) gene in lobular breast cancerEuropean Journal of Cancer
Altered expression of E-cadherin in breast cancerpatterns, mechanisms and clinical significanceEuropean Journal of Cancer
Analysis of chromosome alterations and the E-cadherin and FHIT genes in lobular breast cancer.
The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences.
Chromosome 8p alterations in sporadic and BRCA2 999del5 linked breast cancerJournal of Medical Genetics
Population studies and validation of paternity determinations by six microsatellite lociJournal of Forensic Sciences
Chromosome 8p alterations in sporadic and BRCA2 999de15 linked breast cancerJournal of Medical Genetics
Analysis of the fragile histidine triad (FHIT) gene in lobular breast cancerEuropean Journal of Cancer
The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences.International journal of oncology
Population studies and validation of paternity determinations by six microsatellite loci.
Alteration of the FHIT gene in breast cancer: association with tumour progression and patient survivalImpact of Biotechnology on Cancer Diagnostic & Prognostic Indicators
Leit að próteinum sem bindast afurð æxlisbæligensins FHIT með Yeast-two-hybrid aðferðSamtök um krabbameinsrannsóknir á Íslandi

1999

Chromosome alterations and E-cadherin gene mutations in human lobular breast cancerBritish Journal of Cancer
Altered expression of E-cadherin in breast cancer: Patterns, mechanisms and clinical significanceEuropean Journal of Cancer
Loss of heterozygosity at chromosome 1p in different solid human tumours: association with survivalBritish Journal of Cancer
Somatic alterations of chromosome 8p in sporadic and BRCA2 999del5 linked breast cancerAmerican Journal of Human Genetics
The Brca1 and Brca2 proteins and tumor pathogenesisAnticancer Research
Reduced Fhit expression in sporadic and BRCA2-linked breast carcinomasCancer Research
The Brca1 and Brca2 proteins and tumor pathogenesis.
Replication error in colorectal carcinoma: association with loss of heterozygosity at mismatch repair loci and clinicopathological variables.
Replication error in human breast cancer: comparison with clinical variables and family history of cancer.
Replication error in colorectal carcinoma: Association with loss of heterozygosity at mismatch repair loci and clinicopathological variablesAnticancer Research
Replication error in human breast cancer: Comparison with clinical variables and family history of cancerOncology Reports
Reduced Fhit expression in sporadic and BRCA2-linked breast carcinomas.
The Brca1 and Brca2 proteins and tumor pathogenesisAnticancer Research
Reduced Fhit expression in sporadic and BRCA2-linked breast carcinomasCancer Research
Replication error in human breast cancer: Comparison with clinical variables and family history of cancerOncology Reports
Molecular genetics of breast cancer progressionSeminars in Cancer Biology
Chromosome alterations and E-cadherin gene mutations in human lobular breast cancerBritish Journal of Cancer
Replication error in colorectal carcinoma: Association with loss of heterozygosity at mismatch repair loci and clinicopathological variablesAnticancer Research
Loss of heterozygosity at chromosome 1p in different solid human tumours: Association with survivalBritish Journal of Cancer

1998

Identification of a novel splice-site mutation of the BRCA1 gene in two breast cancer families: screening reveals low frequency in Icelandic breast cancer patients.
High incidence of loss of heterozygosity at chromosome 17p13 in breast tumours from BRCA2 mutation carriersOncogene
High frequency of LOH at chromosome 18q in human breast cancer: Association with high S-phase fraction and low progesterone receptor contentAnticancer Research
Mapping loss of heterozygosity at chromosome 13q: Loss at 13q12-q13 is associated with breast turnout progression and poor prognosisEuropean Journal of Cancer
High incidence of loss of heterozygosity in breast tumors from carriers of the BRCA2 999del5 mutationCancer Research
High incidence of loss of heterozygosity at chromosome 17p13 in breast tumours from BRCA2 mutation carriersOncogene
Identification of a novel splicesite mutation of the BRCAL gene in two breast cancer families: Screening reveals low frequency in icelandic breast cancer patientsHuman Mutation
High incidence of loss of heterozygosity in breast tumors from carriers of the BRCA2 999del5 mutation.
High frequency of LOH at chromosome 18q in human breast cancer: Association with high S-phase fraction and low progesterone receptor contentAnticancer Research
High frequency of LOH at chromosome 18q in human breast cancer: association with high S-phase fraction and low progesterone receptor content.
Chromosome imbalance at the 3p14 region in human breast tumours: High frequency in patients with inherited predisposition due to BRCA2European Journal of Cancer
Identification of a novel splice-site mutation of the BRCA1 gene in two breast cancer families: Screening reveals low frequency in Icelandic breast cancer patientsHuman Mutation
High incidence of loss of heterozygosity in breast tumors from carriers of the BRCA2 999del5 mutationCancer Research
Mapping lass of heterozygosity at chromosome 13q: Loss at 13q12-q13 is associated with breast tumour progression and poor prognosisEuropean Journal of Cancer
Chromosome imbalance at the 3p14 region in human breast tumours: High frequency in patients with inherited predisposition due to BRCA2European Journal of Cancer

1997

Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutationsProceedings of the american society for cancer research
Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutationsCancer Research
Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutationsCancer Research
Loss of heterozygosity at chromosome 7q in human breast cancer: association with clinical variables.
Loss of heterozygosity at chromosome 7q in human breast cancer: Association with clinical variablesAnticancer Research
Meeting report; Molecular Genetics of Cancer. Second joint conference of the American Association for Cancer Reserach and the European Association for Cancer Research. 9-13 Sept. 1997, Oxford University, UKCurrent Drugs ID weekly highlights
Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations.
Loss of heterozygosity at chromosome 7q in human breast cancer: Association with clinical variablesAnticancer Research

1996

High prevalence of the 999del5 mutation in Icelandic breast and ovarian cancer patientsCancer Research
Frequent occurrence of BRCA2 linkage in Icelandic breast cancer families and segregation of a common BRCA2 haplotypeAmerican Journal of Human Genetics
Deletion mapping of chromosome 16 in human breast cancer; Putative location of tumor suppressor gene(s)Cytogenetics and Cell Genetics
Loss of heterozygosity at chromosome 1p in human breast cancer.
Loss of heterozygosity on chromosome arm 3p in nasopharyngeal carcinomaGenes Chromosomes & Cancer
Frequent occurrence of BRCA2 linkage in Icelandic breast cancer families and segregation of a common BRCA2 haplotypeAmerican Journal of Human Genetics
“Elimination test”: Solid tumor progression model based on the nonrandom changes of human chromosome 3 in monochromosomal microcell hybridCancer Genetics and Cytogenetics
Loss of heterozygosity at chromosome 1p in human breast cancer: Association with high S-phase, reduced patient survival and deletions at other chromosome regionsInternational Journal of Oncology
Loss of heterozygosity on chromosome arm 3p in nasopharyngeal carcinomaGenes Chromosomes and Cancer
Report of the fourth international workshop on human chromosome 16 mapping 1995 - Held on 12-14 November 1995 at the University of Leiden, The NetherlandsCytogenetics and Cell Genetics
Frequent occurrence of BRCA2 linkage in Icelandic breast cancer families and segregation of a common BRCA2 haplotype.
High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients.
High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patientsCancer Research
Loss of heterozygosity at chromosome 1p in human breast cancer: Association with high S-phase, reduced patient survival and deletions at other chromosome regionsInternational Journal of Oncology

1995

Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12-q13.
LOSS OF HETEROZYGOSITY AT CHROMOSOME 6Q CORRELATES WITH TUMOR PROGRESSION AND PATIENT SURVIVALInternational Journal of Oncology
Mapping of chromosome 3 alterations in human breast cancer using microsatellite PCR markers: Correlation with clinical variablesInternational Journal of Oncology
DIFFERENT TUMOR TYPES FROM BRCA2 CARRIERS SHOW WILD-TYPE CHROMOSOME DELETIONS ON 13Q12Q13Cancer Research
HIGH-FREQUENCY OF ALLELIC IMBALANCE AT CHROMOSOME REGION 16Q22-23 IN HUMAN BREAST-CANCER - CORRELATION WITH HIGH PGR AND LOW S-PHASEInternational Journal of Cancer
Identification of a breast tumor with microsatellite instability in a potential carrier of the hereditary non‐polyposis colon cancer traitClinical Genetics
Linkage analysis and allelic imbalance in human breast cancer kindreds using microsatellite markers from the short arm of chromosome 3Human Genetics
Loss of heterozygosity at chromosome 6q correlates with tumor progression and patient survivalInternational Journal of Oncology
MAPPING OF CHROMOSOME-3 ALTERATIONS IN HUMAN BREAST-CANCER USING MICROSATELLITE PCR MARKERS - CORRELATION WITH CLINICAL-VARIABLESInternational Journal of Oncology
Loss of heterozygosity on chromosome 9 in human breast cancer: Association with clinical variables and genetic changes at other chromosome regionsInternational Journal of Cancer
LOSS OF HETEROZYGOSITY AT CHROMOSOME-11 IN BREAST-CANCER - ASSOCIATION OF PROGNOSTIC FACTORS WITH GENETIC ALTERATIONSBritish Journal of Cancer
LINKAGE ANALYSIS AND ALLELIC IMBALANCE IN HUMAN BREAST-CANCER KINDREDS USING MICROSATELLITE MARKERS FROM THE SHORT ARM OF CHROMOSOME-3Human Genetics
IDENTIFICATION OF A BREAST-TUMOR WITH MICROSATELLITE INSTABILITY IN A POTENTIAL CARRIER OF THE HEREDITARY NONPOLYPOSIS COLON-CANCER TRAITClinical Genetics
Mapping of chromosome-3 alterations in human breast-cancer using microsatellite PCR markers - correlation with clinical-variables.
Identification of a breast tumor with microsatellite instability in a potential carrier of the hereditary non-polyposis colon cancer trait.
Loss of heterozygosity at chromosome 6q correlates with tumor progression and patient survival.
Different Tumor Types from BRCA2 Carriers Show Wild-Type Chromosome Deletions on 13q12-q13Cancer Research

1994

THE V-ERBA ONCOPROTEIN OF THE AEV TRANSFORMING RETROVIRUS BINDS TO THE PROMOTER REGION OF THE ERYTHROID-SPECIFIC BAND-3 GENESlow Infections of the Central Nervous System: the Legacy of Dr Bjorn Sigurdsson
Norrænn PCR-lyklabanki til rannsókna á erfðamengi mannsinsIcelandic Medical Journal

1993

URINARY SYSTEM TUMORS IN A FAMILYEuropean Journal of Cancer

1992

Rannsóknir á erfðamengi mannsins – Norrænt HUGO verkefniIcelandic Medical Journal

1991

Chromosomal assignment of retinoic acid receptor (RAR) genes in the human, mouse, and rat genomesGenomics
CHROMOSOMAL ASSIGNMENT OF RETINOIC ACID RECEPTOR (RAR) GENES IN THE HUMAN, MOUSE, AND RAT GENOMESGenomics
CHROMOSOMAL ASSIGNMENT OF 5 CANCER-ASSOCIATED RAT GENES - 2 THYROID-HORMONE RECEPTOR (ERBA) GENES, 2 ERBB GENES AND THE RETINOBLASTOMA GENEOncogene
Chromosomal assignment of five cancer-associated rat genes: Two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma geneOncogene
Chromosomal assignment of five cancer-associated rat genes: two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene.
The most frequently lost allelic site in human renal cell carcinoma (D3F15S2) on the short arm of chromosome 3 has homologous sequences on rat chromosome 8.
THE MOST FREQUENTLY LOST ALLELIC SITE IN HUMAN RENAL-CELL CARCINOMA (D3F15S2) ON THE SHORT ARM OF CHROMOSOME-3 HAS HOMOLOGOUS SEQUENCES ON RAT CHROMOSOME-8Cytogenetics and Cell Genetics

1990

The myc gene family proteins and their role in transformation and differentiation.
A gene near the D3F15S2 site on 3p is expressed in normal human kidney but not or only at a severely reduced level in 11 of 15 primary renal cell carcinomas (RCC).
A GENE NEAR THE D3F15S2 SITE ON 3P IS EXPRESSED IN NORMAL HUMAN KIDNEY BUT NOT OR ONLY AT A SEVERELY REDUCED LEVEL IN 11 OF 15 PRIMARY RENAL-CELL CARCINOMAS (RCC)Oncogene
DIFFERENCES IN C-MYC AND PVT-1 AMPLIFICATION IN SEWA SARCOMA SUBLINES SELECTED FOR ADHERENT OR NONADHERENT GROWTHInternational Journal of Cancer
RECOMBINANT PLASMID EXPRESSING THE ENTIRE CODING REGION OF THE BMYC PUTATIVE PROTEINJournal of Clinical & Laboratory Immunology
The myc gene family proteins and their role in transformation and differentiationSeminars in Cancer Biology
Recombinant plasmid expressing the entire coding region of the Bmyc putative protein.
A gene near the D3F15S2 site on 3p is expressed in normal human kidney but not or only at a severely reduced level in 11 of 15 primary renal cell carcinomas (RCC)Oncogene
Recombinant plasmid expressing the entire coding region of the Bmyc putative protein.Journal of Clinical and Laboratory Immunology

1989

Nucleotide sequence of the rat Bmyc geneOncogene
Myc family of genes; structure, expression and activation in tumor pathogenesis
NUCLEOTIDE-SEQUENCE OF THE RAT BMYC GENEOncogene
Nucleotide sequence of the rat Bmyc gene.

1988

Rat c-raf oncogene is located on chromosome 4 and may be activated by sequences from chromosome 13Somatic Cell and Molecular Genetics
STRUCTURE AND EXPRESSION OF B-MYC, A NEW MEMBER OF THE MYC GENE FAMILYMolecular and Cellular Biology
ELEVATED EXPRESSION OF C-MYC AND N-MYC PRODUCES DISTINCT CHANGES IN NUCLEAR FINE-STRUCTURE AND CHROMATIN ORGANIZATIONOncogene
Structure and expression of B-myc, a new member of the myc gene family.
Chromosome localization and expression pattern of Lmyc and Bmyc in murine embryonal carcinoma cells.
Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinomaProceedings of the National Academy of Sciences of the United States of America
Chromosome localization and expression pattern of Lmyc and Bmyc in murine embryonal carcinoma cellsOncogene
CHROMOSOME LOCALIZATION AND EXPRESSION PATTERN OF LMYC AND BMYC IN MURINE EMBRYONAL CARCINOMA-CELLSOncogene
AMPLIFICATION OF C-MYC AND PVT-1 HOMOLOGOUS SEQUENCES IN ACUTE NONLYMPHATIC LEUKEMIALeukemia Research
Drosophila homolog of the murine Int-1 protooncogeneProceedings of the National Academy of Sciences of the United States of America
CONSISTENT CHROMOSOME-3P DELETION AND LOSS OF HETEROZYGOSITY IN RENAL-CELL CARCINOMAProceedings of the National Academy of Sciences of the United States of America
Elevated expression of c-myc and N-myc produces distinct changes in nuclear fine structure and chromatin organization.
Structure and expression of B-myc, a new member of the myc gene familyMolecular and Cellular Biology
RAT C-RAF ONCOGENE IS LOCATED ON CHROMOSOME-4 AND MAY BE ACTIVATED BY SEQUENCES FROM CHROMOSOME-13Somatic Cell and Molecular Genetics
DROSOPHILA HOMOLOG OF THE MURINE INT-1 PROTOONCOGENEProceedings of the National Academy of Sciences of the United States of America
Elevated expression of c-myc and N-myc produces distinct changes in nuclear fine structure and chromatin organizationOncogene

1987

Mapping of Lmyc and Nmyc to rat chromosomes 5 and 6Somatic Cell and Molecular Genetics
SPECIFIC POLYPEPTIDE DIFFERENCES IN NORMAL VERSUS MALIGNANT HUMAN-BREAST TISSUES BY TWO-DIMENSIONAL ELECTROPHORESISBreast Cancer Research and Treatment
MAPPING OF LMYC AND NMYC TO RAT CHROMOSOME-5 AND CHROMOSOME-6Somatic Cell and Molecular Genetics
The rat MIS1/Pvt-1 locus is syntenic with MYC on chromosome 7.
Specific polypeptide differences in normal versus malignant human breast tissues by two-dimensional electrophoresisBreast Cancer Research and Treatment
THE RAT MIS1/PVT-1 LOCUS IS SYNTENIC WITH MYC ON CHROMOSOME-7Cytogenetics and Cell Genetics
Chromosome abberation and oncogene activation in two histologically related human and rat B-cell tumorsViral Carcinogenesis
SIMILARITIES AND DIFFERENCES IN THE REGULATION OF N-MYC AND C-MYC GENES IN MURINE EMBRYONAL CARCINOMA-CELLSExperimental Cell Research

1986

MULTIPLE CHROMOSOMAL REARRANGEMENTS IN A SPONTANEOUSLY ARISING T(6-7) RAT IMMUNOCYTOMA JUXTAPOSE C-MYC AND IMMUNOGLOBULIN HEAVY-CHAIN SEQUENCESProceedings of the National Academy of Sciences of the United States of America
Catabolite repressive effects of 5-thio-D-glucose on Saccharomyces cerevisiae.
Sjúklingur með krabbamein í blöðruhálskirtli og hægfara eitlafrumuhvítblæði: Fækkun eitilfrumna í blóði eftir estrógen-meðferðIcelandic Medical Journal
CATABOLITE REPRESSIVE EFFECTS OF 5-THIO-D-GLUCOSE ON SACCHAROMYCES-CEREVISIAEJournal of General Microbiology
Catabolite repressive effects of 5-thio-D-glucose on Saccharomyces cerevisiae.Journal of General Microbiology
c-myc activation in spontaneous rat immunocytomas containing a 6;7 chromosomal translocation.Current Topics in Microbiology and Immunology
c-myc activation in spontaneous rat immunocytomas containing a 6;7 chromosomal translocation.
Multiple chromosomal rearrangements in a spontaneously arising t(6;7) rat immunocytoma juxtapose c-myc and immunoglobulin heavy chain sequencesProceedings of the National Academy of Sciences of the United States of America
C-MYC ACTIVATION IN SPONTANEOUS RAT IMMUNOCYTOMAS CONTAINING A 6-7 CHROMOSOMAL TRANSLOCATIONCurrent Topics in Microbiology and Immunology

1985

GENE LOCALIZATION ON SORTED CHROMOSOMES - DEFINITIVE EVIDENCE ON THE RELATIVE POSITIONING OF GENES PARTICIPATING IN THE MOUSE PLASMACYTOMA-ASSOCIATED TYPICAL TRANSLOCATIONProceedings of the National Academy of Sciences of the United States of America
CLONING AND CHARACTERIZATION OF THE DNA-SEQUENCE TRANSPOSED TO THE ONCOGENE C-MYC IN RAT IMMUNOCYTOMAS WITH T(6-7) CHROMOSOMAL TRANSLOCATIONScandinavian Journal of Immunology

1984

Mælingar á Estrógen- og Prógesterón-viðtökum í BrjóstakrabbameinumIcelandic Medical Journal
ISOENZYME PATTERN AND SUBCELLULAR-LOCALIZATION OF HEXOKINASES IN HUMAN-BREAST CANCER AND NONPATHOLOGICAL BREAST-TISSUEInternational Journal of Cancer

Keywords for Specialisation:

Molecular biology