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Sigurður Ingvarsson - Professor
–
School of Health Sciences
Sigurður Ingvarsson
Íslenska
Professor
Professor and director
Location
Tilraunastöð HÍ. í meinafræði - Keldum
Phone
8943235
8943235
Email
siguring [at] hi.is
Unit
Faculty of Medicine
Website
https://keldur.is/is
ORCID site
https://orcid.org/0000-0003-4125-1714
Research portal – Sigurður Ingvarsson
Under construction throughout the autumn semester 2023
 
 
 
 
Courses 2022 - 2023
LÆK314G - Biochemistry and Molecular Biology A
Collaboration
,
Education
1989
,
Ph.D.
,
Karolinska Institutet
,
Tumour Biology
1980
,
B.Sc. Honour
,
University of Iceland
,
Molecular Biology
1979
,
B.Sc
,
University of Iceland
,
Biology
1975
,
Stúdentspróf
,
,
Professional Experience
2001 -
,
Director of the Institute for Experimental Pathology at Keldur,
University of Iceland
1995 -
2001,
Researher/Principal Investigator. Dept. of Pathology,
University of Iceland
1995 -
2001,
Researcher, Faculty of Medicine,,
University of Iceland
1984 -
1989,
Post-doctoral fellow,
Karolinska Institutet
1981 -
1984,
Researcher at the Department of Pathology,
University of Iceland
Published works
2023
Vísindadagur Keldna 2023
Institute for Experimental Pathology, University of Iceland at Keldur
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2022
Institute for Experimental Pathology, University of Iceland at Keldur
2022
Tilraunastöð Háskóla Íslands í meinafræði að Keldum
Ísland - Atvinnuhættir og menning
2021
Hversu sýnilegt er “Icelandic Agricultural Sciences” í alþjóðlegum vefsetrum?
Líffræðiráðstefnan 2021
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2021
Institute for Experimental Pathology, University of Iceland at Keldur
2020
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2020
Institute for Experimental Pathology, University of Iceland at Keldur
2019
Vefsetursgreining á „Icelandic Agricultural Sciences“
Líffræðiráðstefnan 2019 – Líffræðifélag Íslands. Reykjavík 17.-19. október 2019
Hif umritunarþáttur og Nóbelsverðlaunin í líf- og læknisfræði árið 2019
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2019
Institute for Experimental Pathology, University of Iceland at Keldur
2018
Keldur - Leiðandi stofnun í rannsóknum á dýrasjúkdómum
Institute for Experimental Pathology, University of Iceland at Keldur
Vísindadagur á Keldum á sjötíu ára starfsafmæli
Bændablaðið
Vísindadagur á Keldum - Keldur 70 ára, 1948-2018
Institute for Experimental Pathology, University of Iceland at Keldur
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2018
Institute for Experimental Pathology, University of Iceland at Keldur
Hvað hefur vísindamaðurinn Sigurður Ingvarsson rannsakað?
Vísindavefurinn
Smitandi æxlisfrumur í ljósi þróunar
2017
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2017
Institute for Experimental Pathology, University of Iceland at Keldur
Genomic, proteomic and clinicopathological events in carriers of the Icelandic BRCA2 999del5 founder mutation
3rd World Congress on Cancer and Prevention Methods - "Scientific Future Group", Barcelona
2016
Epigenetic control of MLH1 expression by promoter variant and methylation spreading from Alu repeats
The 18th Nordic Congress in Human Genetics, Reykjavik
Vísindadagur á Keldum 2016
Institute for Experimental Pathology, University of Iceland at Keldur
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2016
Institute for Experimental Pathology, University of Iceland at Keldur
2015
MicroRNA451 bælir æxlisvöxt með því að minnka tjáningu IL6R gens
Icelandic Medical Journal
DNA viðgerðir og Nóbelsverðlaunin í efnafræði árið 2015
Institute for Experimental Pathology, University of Iceland at Keldur
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2015
Institute for Experimental Pathology, University of Iceland at Keldur
2014
Editorial
Icelandic Agricultural Sciences
Icelandic Agricultural Sciences. Vel sýnilegt í alþjóðlega viðurkenndum vefsetrum
Landsýn - Vísindaþing Landbúnaðarins
Vísindadagur á Keldum 2014
Institute for Experimental Pathology, University of Iceland at Keldur
The IL6R Expression is Downregulated by miR-451 in Tumour Progression
Scandinavian Journal of Immunology
Greining á ritverkum Keldna 2004-2013
Institute for Experimental Pathology, University of Iceland at Keldur
MicroRNA-451 suppresses tumor cell growth by down-regulating IL6R gene expression
Cancer Epidemiology
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2014
Úttekt á sýnileika vísindatímaritsins „Icelandic Agricultural Sciences“ í alþjóðlegum vefsetrum
Vísindadagur Keldna 2014
Hversu sýnilegt er “Icelandic Agricultural Sciences” í alþjóðlegum vefsetrum?
Skrína — rit um auðlinda-, landbúnaðar- og umhverfisvísindi
THE GENETIC LANDSCAPE OF FAMILIAL BREAST CANCER IN ICELAND
Anticancer Research
Virkni Hif-umritunarþáttar er stýrt með prótein-niðurbroti
Vísindadagur Keldna 2014
2013
Greining á tímaritinu „Icelandic Agricultural Sciences“ skv. alþjóðlega viðurkenndum vefsetrum
Líffræðiráðstefnan 2013
Hlutverk Limd1 í stjórnunarferli Hif1 umritunarþáttar
Líffræðiráðstefnan 2013
Rannsóknir eru undirstaða þróunar og hagsældar í landbúnaði
Bændablaðið
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2013
Institute for Experimental Pathology, University of Iceland at Keldur
Anders Jahre-verðlaunin veitt fyrir rannsóknir á sykursýki
Icelandic Medical Journal
Editorial
Icelandic Agricultural Sciences
In memoriam Bjorn Sigurdsson born 100 years ago
Icelandic Agricultural Sciences
Icelandic Agricultural Sciences er viðurkennt ISI-vísindarit
Landsýn – vísindaþing landbúnaðarins 2013
2012
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2012
Institute for Experimental Pathology, University of Iceland at Keldur
Greining á ISI-ritverkum Tilraunastöðvar Háskóla Íslands í meinafræði að Keldum frá árunum 2002-2011
Vísindadagur Keldna 2012
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
Nature Cell Biology
Meinafræði að Keldum í minningu Guðmundar Georgssonar
Institute for Experimental Pathology, University of Iceland at Keldur
Icelandic Agricultural Sciences. Vinsæll vettvangur til að birta niðurstöður íslenskra skógfræðirannsókna
Fagráðstefna Skógræktar
Demethylation of the region around exon 2 of MLH1 gene in gastrointestinal cancer
Anticancer Research
Icelandic Agricultural Sciences. Vinsæll vettvangur til að birta niðurstöður íslenskra skógfræðirannsókna
Fagráðstefna Skógræktar
Brautryðjandi í sykursýkisrannsóknum fær Jahre-verðlaunin
Icelandic Medical Journal
Rannsóknir og þjónusta á Keldum í þágu dýraheilbrigðis
Bændablaðið
Universal RNA editing in a human liver at the fetal stage
Open Journal of Genetics
Hif, lykilumritunarþáttur í efnaskiptum og æðamyndun
Institute for Experimental Pathology, University of Iceland at Keldur
Universal RNA editing in a human liver at the fetal stage
Open Journal of Genetics
Vísindadagur á Keldum 2012
Institute for Experimental Pathology, University of Iceland at Keldur
Icelandic Agricultural Sciences (IAS), viðurkennt ISI-vísindarit
Vísindadagur á Keldum 2012
Demethylation of the region around exon 2 of MLH1 gene in gastrointestinal cancer.
Demethylation of the Region around Exon 2 of MLH1 Gene in Gastrointestinal Cancer
Anticancer Research
2011
Anders Jahre-verðlaunin
Laeknabladid
Stökkbreytingar sem leiða til æxlisvaxtar: Náttúrulegt val?
Læknadagar 2011
Metýlun stjórnraðar og tjáning Lactoferrins í lungnaæxlum.
Vísindi á vordögum 2011
Spreading of Alu Methylation to the Promoter of the MLH1 Gene in Gastrointestinal Cancer
Plos One
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2011
Institute for Experimental Pathology, University of Iceland at Keldur
Icelandic Agricultural Sciences er nú viðurkennt ISI-tímarit
Líffræðiráðstefnan 2011
Ávarp - Lofsvert Lagnaverk 2009
Fréttabréf Lagnafélags Íslands
Icelandic Agricultural Sciences er nú viðurkennt ISI-vísindarit
Fræðaþing Landbúnaðarins
Quantitative Analysis of miRNA Expression in Seven Human Foetal and Adult Organs
Plos One
Spreading of alu methylation to the promoter of the mlh1 gene in gastrointestinal cancer
PLoS ONE
Quantitative analysis of miRNa expression in seven human foetal and adult organs
PLoS ONE
2010
Þroski, vöxtur og starfsemi vessaæða í heilbrigðum og sjúkum vef
Institute for Experimental Pathology, University of Iceland at Keldur
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2010
Institute for Experimental Pathology, University of Iceland at Keldur
Quantitative analysis of miRNA expression in several developmental stages of human livers
Hepatology Research
The MLH1-93 promoter variant influences gene expression
Cancer Epidemiology
Tjáning á LIMD1 og HIF1-alpha próteinum í nýrnaæxlum
Vísindi á vordögum
Vísindadagur á Keldum 2010
Institute for Experimental Pathology, University of Iceland at Keldur
Icelandic Agricultural Sciences
Vísindadagur á Keldum 2010
2009
Nóbelsverðlaunin í lífeðlis- og læknisfræði 2009: Litningaendar og lífhvatinn telómerase
Tímarit um raunvísindi og stærðfræði
Nóbelsverðlaunin í líf- og læknisfræði 2009: Litningaendar og telómerasi
Institute for Experimental Pathology, University of Iceland at Keldur
Lactoferrin prótein tjáning er minnkuð í lungnaæxlum
Líffræðiráðstefnan 2009
The Nobel Prize in Physiology or Medicine 2009; How chromosomes are protected by telomeres and the enzyme telomerase
Chemistry Seminars - University of Iceland
Identification of miRNAs in a liver of a human fetus by a modified method
PLoS ONE
Identification of miRNAs in a Liver of a Human Fetus by a Modified Method
Plos One
Frumusækni mæði-visnuveiru
XIV Vísindaráðstefna Háskóla Íslands
Hvernig litningaendar eru varðir af litningaendum og lífhvatinn telómerasi
Fræðslufundur Erfða- og Sameindalæknisfræðideildar Landspítala Háskólasjúkrahúss
The sixty year anniversary of the Institute for Experimental Pathology, University of Iceland at Keldur Preface
Icelandic Agricultural Sciences
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2009
Institute for Experimental Pathology, University of Iceland at Keldur
Lactoferrin prótein tjáning er minnkuð í lungnaæxlum
Vísindi á vordögum
2008
Genomic instability in breast cancer
The 1st international conference on drug design and discovery
Genomic instability in breast cancer
Frontiers in Breast Cancer Research
Minnkuð lactotransferrin tjáning í lungnaæxlum
Vísindi á vordögum 2008
60 ára starfsafmæli Tilraunastöðvar Háskóla Íslands í meinafræði að Keldum
Bændablaðið
International Conference on Fish Diseases and Fish Immunology. In Celebration of the 60th Anniversary of the Institute for Experimental Pathology, University of Iceland, Keldur
Institute for Experimental Pathology, University of Iceland at Keldur
Ársskýrsla Tilraunatöðvar Háskóla Íslands í meinafræði að Keldum - 2008
Institute for Experimental Pathology, University of Iceland at Keldur
Icelandic Agricultural Sciences: Alþjóðlegt tímarit á ensku fyrir vísindagreinar í lífvísindum
Fræðaþing Landbúnaðarins
In vitro analysis of expression vectors for DNA vaccination of horses: The effect of a Kozak sequence
Acta Veterinaria Scandinavica
Population Approach in Breast Cancer Research Based on Integration of Genetic, Clinicopathological and Genealogical Clues
The Open Cancer Journal
CELLULAR BIOLOGY OF BREAST CANCER, FOCUSING ON GENOMIC AND CLINICOPATHOLOGICAL EVENTS IN CARRIERS OF A BRCA2 FOUNDER MUTATION
Anticancer Research
In vitro analysis of expression vectors for DNA vaccination of horses: the effect of a Kozak sequence
Acta Veterinaria Scandinavica
2007
A29T fjölbreytileiki í LTF er algengur í lungnaæxlum
Vísindi á vordögum 2007
Duplicated sequence motif in the long terminal repeat of maedi-visna viras extends cell tropism and is associated with neurovirulence
Journal of Virology
Duplicated sequence motif in the long terminal repeat of maedi-visna virus extends cell tropism and is associated with neurovirulence
Journal of Virology
Taugasækni mæði-visnuveirunnar
Þrettánda ráðstefnan um rannsóknir í líf- og heilbrigðisvísindum í Háskóla Íslands
Ársskýrsla 2007 - Tilraunastöð Háskóla Íslands í meinafræði að Keldum
Institute for Experimental Pathology, University of Iceland at Keldur
In vitro analysis of expression vectors for DNA vaccination in horses
3rd International Workshop on Allergic Diseases of the horse
Stökkbreytingaleit í LIMD1 og LTF genum á 3p21.3 í æxlum
Þrettánda ráðstefnan um rannsóknir í líf- og heilbrigðisvísindum í Háskóla Íslands
2006
Ársskýrsla 2006 - Tilraunastöð Háskóla Íslands í meinafræði að Keldum
Institute for Experimental Pathology, University of Iceland at Keldur
Vísindadagur á Keldum 2006
Institute for Experimental Pathology, University of Iceland at Keldur
Taugasækni mæði-visnuveirunnar
Vísindadagur á Keldum
Sameindalíffræði RNA inngrips
University of Iceland
Nóbelsverðlaun í lífeðlis- eða læknisfræði 2006 – RNA íhlutun
Institute for Experimental Pathology, University of Iceland at Keldur
Leit að stökkbreytingum í LIMD1 og LTF genum á CER1 svæði á mannalitningi 3p21.3 í 10 mismunandi
Vísindadagur á Keldum 2006
Hvað er RNA-inngrip?
Genomic instability and breast cancer progression
Cancer Genomics and Proteomics
Erfðagreyping og sjúkdómsmynd
Institute for Experimental Pathology, University of Iceland at Keldur
2005
Icelandic Agricultural Sciences - Alþjóðlegt tímarit fyrir vísindagreinar í lífvísindum
Fræðaþing Landbúnaðarins
Deletions at the chromosome 3 common eliminated region 1 on 3p21.3 in human breast tumors.
Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin
Oncogene
Deletions at the chromosome 3 common eliminated region 1 on 3p21.3 in human breast tumors
Breast Cancer Research
Tumor suppressor genes on human chromosome 3 and cancer pathogenesis
Cancer Genomics and Proteomics
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2005
Institute for Experimental Pathology, University of Iceland at Keldur
[Uniparental disomy of chromosome 11 in a patient with Beckwith-Wiedemann syndrome. First reported case in Iceland].
Breytingar á litningi 3 og framvinda æxlisvaxtar í nagdýrum og mönnum
Ralt er æxlisbæliprótein sem hefur áhrif á lyfjanæmi
Institute for Experimental Pathology, University of Iceland at Keldur
Uniparental disomy of chromosome 11 in a patient with Beckwith-Wiedemann syndrome. First reported case in Iceland | Tvístæða litnings nr. 11 frá föður hjá sjúklingi með Beckwith-Wiedemann heilkenni. Fyrsta greining á Íslandi--Sjúkratilfelli.
Læknabladid
Tumour suppressor genes at chromosome 3 and cancer pathogenesis
2005 World DNA and Genome Day
2004
Genetics of breast cancer.
Tilraunastöð Háskóla Íslands í meinafræði að Keldum - Ársskýrsla 2004
Institute for Experimental Pathology, University of Iceland at Keldur
Ósamfelldar úrfellingar á C3CER1 litningasvæði eru algengar í æxlum frá tíu mismunandi vefjum
Afmælisráðstefna Líffræðifélags Íslands og Líffræðistofnunar Háskólans: Líffræði - vaxandi vísindi
Interstitial deletions including chromosome 3 common eliminated region I (C3CERI) prevail in human solid tumors from 10 different tissues
Genes Chromosomes & Cancer
Genetics of breast cancer
Drugs of Today
Vísindadagur á Keldum 2004
Institute for Experimental Pathology, University of Iceland at Keldur
Nóbelsverðlaunin í efnafræði 2004 – Ubiquitin miðlað próteinniðurbrot
RAUST - Tímarit um raunvísindi og stærðfræði
Taugasækni mæði-visnuveiru
Afmælisráðstefna Líffræðifélags Íslands og Líffræðistofnunar Háskólans: Líffræði - vaxandi vísindi
Duplicated sequence motif in the long terminal repeat of maedi-visna virus extends cell tropism and is associated with neurovirulence
Molecular Mechanism of HIV Pathogenesis (X7). Keystone Symposia
Taugasækni mæði-visnuveirunnar
Vísindadagur á Keldum 2004
ALTERATIONS AT CHROMOSOME 3 AND CANCER PATHOGENESIS
Anticancer Research
2003
Germline mutations in DNA repair and cell cycle checkpoint genes: consequential somatic gene alterations and genome instability.
Erfðabreytileiki íslenska hestastofnsins
XI. ráðstefnan um rannsóknir í læknadeild, tannlæknadeild og lyfjafræðideild Háskóla Íslands
Rannsóknir á E-cadherini, beta-catenini og FHIT í magakrabbameinum
XI. ráðstefnan um rannsóknir í læknadeild, tannlæknadeild og lyfjafræðideild Háskóla Íslands
Tap á arfblendni innan C3CER1 svæðis á litningi 3p21.3 í æxlum frá tíu mismunandi líffærum
XI. ráðstefnan um rannsóknir í læknadeild, tannlæknadeild og lyfjafræðideild Háskóla Íslands
Molecular Genetics of Breast Cancer
International Journal of Human Genetics
2002
Epidemiology — laboratory
European Journal of Cancer
Loss of heterozygosity at the FHIT gene in different solid human tumours and its association with survival in colorectal cancer patients
Anticancer Research
High frequency of LOH, MSI and abnormal expression of FHIT in gastric cancer
European Journal of Cancer
Loss of heterozygosity at the FHIT gene in different solid human tumours and its association with survival in colorectal cancer patients.
Mutation analysis of the CHK2 gene in breast carcinoma and other cancers
Breast Cancer Research
High frequency of LOH, MSI and abnormal expression of FHIT in gastric cancer
European Journal of Cancer
Loss of heterozygosity at the FHIT gene in different solid human tumours and its association with survival in colorectal cancer patients
Anticancer Research
Mutation analysis of the CHK2 gene in breast carcinoma and other cancers
Breast Cancer Research
Pattern of FHIT LOH in different solid human tumors; association with survival in colorectal cancer patients
Cancer Epidemiology Biomarkers & Prevention
Vísindadagur á Keldum 2002
Institute for Experimental Pathology, University of Iceland at Keldur
2001
Alterations of the FHIT gene in breast cancer: Association with tumor progression and patient survival
Cancer Detection and Prevention
Alterations of the FHIT gene in breast cancer: association with tumor progression and patient survival.
Breast cancer: introduction
Seminars in Cancer Biology
Alterations of E-cadherin and beta-catenin in gastric cancer
Bmc Cancer
Alterations of E-cadherin and beta-catenin in gastric cancer.
BMC cancer [electronic resource]
Similar regions of human chromosome 3 are eliminated from or retained in human/human and human/mouse microcell hybrids during tumor growth in severe combined immunodeficient (SCID) mice
Proceedings of the National Academy of Sciences of the United States of America
FHIT alterations in breast cancer
Seminars in Cancer Biology
Alterations of the FHIT gene in breast cancer: association with tumor progression and patient survival.
Cancer Detection and Prevention
2000
Molecular biology of breast cancer.
Oncology reports
Population studies and validation of paternity determinations by six microsatellite loci
Journal of Forensic Sciences
The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences
International Journal of Oncology
Molecular biology of breast cancer.
Altered expression of E-cadherin in breast cancer: patterns, mechanisms and clinical significance
European Journal of Cancer
Analysis of the fragile histidine triad (FHIT) gene in lobular breast cancer
European Journal of Cancer
Altered expression of E-cadherin in breast cancerpatterns, mechanisms and clinical significance
European Journal of Cancer
Analysis of chromosome alterations and the E-cadherin and FHIT genes in lobular breast cancer.
The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences.
Chromosome 8p alterations in sporadic and BRCA2 999del5 linked breast cancer
Journal of Medical Genetics
Population studies and validation of paternity determinations by six microsatellite loci
Journal of Forensic Sciences
Chromosome 8p alterations in sporadic and BRCA2 999de15 linked breast cancer
Journal of Medical Genetics
Analysis of the fragile histidine triad (FHIT) gene in lobular breast cancer
European Journal of Cancer
The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences.
International journal of oncology
Population studies and validation of paternity determinations by six microsatellite loci.
Alteration of the FHIT gene in breast cancer: association with tumour progression and patient survival
Impact of Biotechnology on Cancer Diagnostic & Prognostic Indicators
Leit að próteinum sem bindast afurð æxlisbæligensins FHIT með Yeast-two-hybrid aðferð
Samtök um krabbameinsrannsóknir á Íslandi
1999
Chromosome alterations and E-cadherin gene mutations in human lobular breast cancer
British Journal of Cancer
Altered expression of E-cadherin in breast cancer: Patterns, mechanisms and clinical significance
European Journal of Cancer
Loss of heterozygosity at chromosome 1p in different solid human tumours: association with survival
British Journal of Cancer
Somatic alterations of chromosome 8p in sporadic and BRCA2 999del5 linked breast cancer
American Journal of Human Genetics
The Brca1 and Brca2 proteins and tumor pathogenesis
Anticancer Research
Reduced Fhit expression in sporadic and BRCA2-linked breast carcinomas
Cancer Research
The Brca1 and Brca2 proteins and tumor pathogenesis.
Replication error in colorectal carcinoma: association with loss of heterozygosity at mismatch repair loci and clinicopathological variables.
Replication error in human breast cancer: comparison with clinical variables and family history of cancer.
Replication error in colorectal carcinoma: Association with loss of heterozygosity at mismatch repair loci and clinicopathological variables
Anticancer Research
Replication error in human breast cancer: Comparison with clinical variables and family history of cancer
Oncology Reports
Reduced Fhit expression in sporadic and BRCA2-linked breast carcinomas.
The Brca1 and Brca2 proteins and tumor pathogenesis
Anticancer Research
Reduced Fhit expression in sporadic and BRCA2-linked breast carcinomas
Cancer Research
Replication error in human breast cancer: Comparison with clinical variables and family history of cancer
Oncology Reports
Molecular genetics of breast cancer progression
Seminars in Cancer Biology
Chromosome alterations and E-cadherin gene mutations in human lobular breast cancer
British Journal of Cancer
Replication error in colorectal carcinoma: Association with loss of heterozygosity at mismatch repair loci and clinicopathological variables
Anticancer Research
Loss of heterozygosity at chromosome 1p in different solid human tumours: Association with survival
British Journal of Cancer
1998
Identification of a novel splice-site mutation of the BRCA1 gene in two breast cancer families: screening reveals low frequency in Icelandic breast cancer patients.
High incidence of loss of heterozygosity at chromosome 17p13 in breast tumours from BRCA2 mutation carriers
Oncogene
High frequency of LOH at chromosome 18q in human breast cancer: Association with high S-phase fraction and low progesterone receptor content
Anticancer Research
Mapping loss of heterozygosity at chromosome 13q: Loss at 13q12-q13 is associated with breast turnout progression and poor prognosis
European Journal of Cancer
High incidence of loss of heterozygosity in breast tumors from carriers of the BRCA2 999del5 mutation
Cancer Research
High incidence of loss of heterozygosity at chromosome 17p13 in breast tumours from BRCA2 mutation carriers
Oncogene
Identification of a novel splicesite mutation of the BRCAL gene in two breast cancer families: Screening reveals low frequency in icelandic breast cancer patients
Human Mutation
High incidence of loss of heterozygosity in breast tumors from carriers of the BRCA2 999del5 mutation.
High frequency of LOH at chromosome 18q in human breast cancer: Association with high S-phase fraction and low progesterone receptor content
Anticancer Research
High frequency of LOH at chromosome 18q in human breast cancer: association with high S-phase fraction and low progesterone receptor content.
Chromosome imbalance at the 3p14 region in human breast tumours: High frequency in patients with inherited predisposition due to BRCA2
European Journal of Cancer
Identification of a novel splice-site mutation of the BRCA1 gene in two breast cancer families: Screening reveals low frequency in Icelandic breast cancer patients
Human Mutation
High incidence of loss of heterozygosity in breast tumors from carriers of the BRCA2 999del5 mutation
Cancer Research
Mapping lass of heterozygosity at chromosome 13q: Loss at 13q12-q13 is associated with breast tumour progression and poor prognosis
European Journal of Cancer
Chromosome imbalance at the 3p14 region in human breast tumours: High frequency in patients with inherited predisposition due to BRCA2
European Journal of Cancer
1997
Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations
Proceedings of the american society for cancer research
Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations
Cancer Research
Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations
Cancer Research
Loss of heterozygosity at chromosome 7q in human breast cancer: association with clinical variables.
Loss of heterozygosity at chromosome 7q in human breast cancer: Association with clinical variables
Anticancer Research
Meeting report; Molecular Genetics of Cancer. Second joint conference of the American Association for Cancer Reserach and the European Association for Cancer Research. 9-13 Sept. 1997, Oxford University, UK
Current Drugs ID weekly highlights
Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations.
Loss of heterozygosity at chromosome 7q in human breast cancer: Association with clinical variables
Anticancer Research
1996
High prevalence of the 999del5 mutation in Icelandic breast and ovarian cancer patients
Cancer Research
Frequent occurrence of BRCA2 linkage in Icelandic breast cancer families and segregation of a common BRCA2 haplotype
American Journal of Human Genetics
Deletion mapping of chromosome 16 in human breast cancer; Putative location of tumor suppressor gene(s)
Cytogenetics and Cell Genetics
Loss of heterozygosity at chromosome 1p in human breast cancer.
Loss of heterozygosity on chromosome arm 3p in nasopharyngeal carcinoma
Genes Chromosomes & Cancer
Frequent occurrence of BRCA2 linkage in Icelandic breast cancer families and segregation of a common BRCA2 haplotype
American Journal of Human Genetics
“Elimination test”: Solid tumor progression model based on the nonrandom changes of human chromosome 3 in monochromosomal microcell hybrid
Cancer Genetics and Cytogenetics
Loss of heterozygosity at chromosome 1p in human breast cancer: Association with high S-phase, reduced patient survival and deletions at other chromosome regions
International Journal of Oncology
Loss of heterozygosity on chromosome arm 3p in nasopharyngeal carcinoma
Genes Chromosomes and Cancer
Report of the fourth international workshop on human chromosome 16 mapping 1995 - Held on 12-14 November 1995 at the University of Leiden, The Netherlands
Cytogenetics and Cell Genetics
Frequent occurrence of BRCA2 linkage in Icelandic breast cancer families and segregation of a common BRCA2 haplotype.
High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients.
High prevalence of the 999del5 mutation in icelandic breast and ovarian cancer patients
Cancer Research
Loss of heterozygosity at chromosome 1p in human breast cancer: Association with high S-phase, reduced patient survival and deletions at other chromosome regions
International Journal of Oncology
1995
Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12-q13.
LOSS OF HETEROZYGOSITY AT CHROMOSOME 6Q CORRELATES WITH TUMOR PROGRESSION AND PATIENT SURVIVAL
International Journal of Oncology
Mapping of chromosome 3 alterations in human breast cancer using microsatellite PCR markers: Correlation with clinical variables
International Journal of Oncology
DIFFERENT TUMOR TYPES FROM BRCA2 CARRIERS SHOW WILD-TYPE CHROMOSOME DELETIONS ON 13Q12Q13
Cancer Research
HIGH-FREQUENCY OF ALLELIC IMBALANCE AT CHROMOSOME REGION 16Q22-23 IN HUMAN BREAST-CANCER - CORRELATION WITH HIGH PGR AND LOW S-PHASE
International Journal of Cancer
Identification of a breast tumor with microsatellite instability in a potential carrier of the hereditary non‐polyposis colon cancer trait
Clinical Genetics
Linkage analysis and allelic imbalance in human breast cancer kindreds using microsatellite markers from the short arm of chromosome 3
Human Genetics
Loss of heterozygosity at chromosome 6q correlates with tumor progression and patient survival
International Journal of Oncology
MAPPING OF CHROMOSOME-3 ALTERATIONS IN HUMAN BREAST-CANCER USING MICROSATELLITE PCR MARKERS - CORRELATION WITH CLINICAL-VARIABLES
International Journal of Oncology
Loss of heterozygosity on chromosome 9 in human breast cancer: Association with clinical variables and genetic changes at other chromosome regions
International Journal of Cancer
LOSS OF HETEROZYGOSITY AT CHROMOSOME-11 IN BREAST-CANCER - ASSOCIATION OF PROGNOSTIC FACTORS WITH GENETIC ALTERATIONS
British Journal of Cancer
LINKAGE ANALYSIS AND ALLELIC IMBALANCE IN HUMAN BREAST-CANCER KINDREDS USING MICROSATELLITE MARKERS FROM THE SHORT ARM OF CHROMOSOME-3
Human Genetics
IDENTIFICATION OF A BREAST-TUMOR WITH MICROSATELLITE INSTABILITY IN A POTENTIAL CARRIER OF THE HEREDITARY NONPOLYPOSIS COLON-CANCER TRAIT
Clinical Genetics
Mapping of chromosome-3 alterations in human breast-cancer using microsatellite PCR markers - correlation with clinical-variables.
Identification of a breast tumor with microsatellite instability in a potential carrier of the hereditary non-polyposis colon cancer trait.
Loss of heterozygosity at chromosome 6q correlates with tumor progression and patient survival.
Different Tumor Types from BRCA2 Carriers Show Wild-Type Chromosome Deletions on 13q12-q13
Cancer Research
1994
THE V-ERBA ONCOPROTEIN OF THE AEV TRANSFORMING RETROVIRUS BINDS TO THE PROMOTER REGION OF THE ERYTHROID-SPECIFIC BAND-3 GENE
Slow Infections of the Central Nervous System: the Legacy of Dr Bjorn Sigurdsson
Norrænn PCR-lyklabanki til rannsókna á erfðamengi mannsins
Icelandic Medical Journal
1993
URINARY SYSTEM TUMORS IN A FAMILY
European Journal of Cancer
1992
Rannsóknir á erfðamengi mannsins – Norrænt HUGO verkefni
Icelandic Medical Journal
1991
Chromosomal assignment of retinoic acid receptor (RAR) genes in the human, mouse, and rat genomes
Genomics
CHROMOSOMAL ASSIGNMENT OF RETINOIC ACID RECEPTOR (RAR) GENES IN THE HUMAN, MOUSE, AND RAT GENOMES
Genomics
CHROMOSOMAL ASSIGNMENT OF 5 CANCER-ASSOCIATED RAT GENES - 2 THYROID-HORMONE RECEPTOR (ERBA) GENES, 2 ERBB GENES AND THE RETINOBLASTOMA GENE
Oncogene
Chromosomal assignment of five cancer-associated rat genes: Two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene
Oncogene
Chromosomal assignment of five cancer-associated rat genes: two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene.
The most frequently lost allelic site in human renal cell carcinoma (D3F15S2) on the short arm of chromosome 3 has homologous sequences on rat chromosome 8.
THE MOST FREQUENTLY LOST ALLELIC SITE IN HUMAN RENAL-CELL CARCINOMA (D3F15S2) ON THE SHORT ARM OF CHROMOSOME-3 HAS HOMOLOGOUS SEQUENCES ON RAT CHROMOSOME-8
Cytogenetics and Cell Genetics
1990
The myc gene family proteins and their role in transformation and differentiation.
A gene near the D3F15S2 site on 3p is expressed in normal human kidney but not or only at a severely reduced level in 11 of 15 primary renal cell carcinomas (RCC).
A GENE NEAR THE D3F15S2 SITE ON 3P IS EXPRESSED IN NORMAL HUMAN KIDNEY BUT NOT OR ONLY AT A SEVERELY REDUCED LEVEL IN 11 OF 15 PRIMARY RENAL-CELL CARCINOMAS (RCC)
Oncogene
DIFFERENCES IN C-MYC AND PVT-1 AMPLIFICATION IN SEWA SARCOMA SUBLINES SELECTED FOR ADHERENT OR NONADHERENT GROWTH
International Journal of Cancer
RECOMBINANT PLASMID EXPRESSING THE ENTIRE CODING REGION OF THE BMYC PUTATIVE PROTEIN
Journal of Clinical & Laboratory Immunology
The myc gene family proteins and their role in transformation and differentiation
Seminars in Cancer Biology
Recombinant plasmid expressing the entire coding region of the Bmyc putative protein.
A gene near the D3F15S2 site on 3p is expressed in normal human kidney but not or only at a severely reduced level in 11 of 15 primary renal cell carcinomas (RCC)
Oncogene
Recombinant plasmid expressing the entire coding region of the Bmyc putative protein.
Journal of Clinical and Laboratory Immunology
1989
Nucleotide sequence of the rat Bmyc gene
Oncogene
Myc family of genes; structure, expression and activation in tumor pathogenesis
NUCLEOTIDE-SEQUENCE OF THE RAT BMYC GENE
Oncogene
Nucleotide sequence of the rat Bmyc gene.
1988
Rat c-raf oncogene is located on chromosome 4 and may be activated by sequences from chromosome 13
Somatic Cell and Molecular Genetics
STRUCTURE AND EXPRESSION OF B-MYC, A NEW MEMBER OF THE MYC GENE FAMILY
Molecular and Cellular Biology
ELEVATED EXPRESSION OF C-MYC AND N-MYC PRODUCES DISTINCT CHANGES IN NUCLEAR FINE-STRUCTURE AND CHROMATIN ORGANIZATION
Oncogene
Structure and expression of B-myc, a new member of the myc gene family.
Chromosome localization and expression pattern of Lmyc and Bmyc in murine embryonal carcinoma cells.
Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma
Proceedings of the National Academy of Sciences of the United States of America
Chromosome localization and expression pattern of Lmyc and Bmyc in murine embryonal carcinoma cells
Oncogene
CHROMOSOME LOCALIZATION AND EXPRESSION PATTERN OF LMYC AND BMYC IN MURINE EMBRYONAL CARCINOMA-CELLS
Oncogene
AMPLIFICATION OF C-MYC AND PVT-1 HOMOLOGOUS SEQUENCES IN ACUTE NONLYMPHATIC LEUKEMIA
Leukemia Research
Drosophila homolog of the murine Int-1 protooncogene
Proceedings of the National Academy of Sciences of the United States of America
CONSISTENT CHROMOSOME-3P DELETION AND LOSS OF HETEROZYGOSITY IN RENAL-CELL CARCINOMA
Proceedings of the National Academy of Sciences of the United States of America
Elevated expression of c-myc and N-myc produces distinct changes in nuclear fine structure and chromatin organization.
Structure and expression of B-myc, a new member of the myc gene family
Molecular and Cellular Biology
RAT C-RAF ONCOGENE IS LOCATED ON CHROMOSOME-4 AND MAY BE ACTIVATED BY SEQUENCES FROM CHROMOSOME-13
Somatic Cell and Molecular Genetics
DROSOPHILA HOMOLOG OF THE MURINE INT-1 PROTOONCOGENE
Proceedings of the National Academy of Sciences of the United States of America
Elevated expression of c-myc and N-myc produces distinct changes in nuclear fine structure and chromatin organization
Oncogene
1987
Mapping of Lmyc and Nmyc to rat chromosomes 5 and 6
Somatic Cell and Molecular Genetics
SPECIFIC POLYPEPTIDE DIFFERENCES IN NORMAL VERSUS MALIGNANT HUMAN-BREAST TISSUES BY TWO-DIMENSIONAL ELECTROPHORESIS
Breast Cancer Research and Treatment
MAPPING OF LMYC AND NMYC TO RAT CHROMOSOME-5 AND CHROMOSOME-6
Somatic Cell and Molecular Genetics
The rat MIS1/Pvt-1 locus is syntenic with MYC on chromosome 7.
Specific polypeptide differences in normal versus malignant human breast tissues by two-dimensional electrophoresis
Breast Cancer Research and Treatment
THE RAT MIS1/PVT-1 LOCUS IS SYNTENIC WITH MYC ON CHROMOSOME-7
Cytogenetics and Cell Genetics
Chromosome abberation and oncogene activation in two histologically related human and rat B-cell tumors
Viral Carcinogenesis
SIMILARITIES AND DIFFERENCES IN THE REGULATION OF N-MYC AND C-MYC GENES IN MURINE EMBRYONAL CARCINOMA-CELLS
Experimental Cell Research
1986
MULTIPLE CHROMOSOMAL REARRANGEMENTS IN A SPONTANEOUSLY ARISING T(6-7) RAT IMMUNOCYTOMA JUXTAPOSE C-MYC AND IMMUNOGLOBULIN HEAVY-CHAIN SEQUENCES
Proceedings of the National Academy of Sciences of the United States of America
Catabolite repressive effects of 5-thio-D-glucose on Saccharomyces cerevisiae.
Sjúklingur með krabbamein í blöðruhálskirtli og hægfara eitlafrumuhvítblæði: Fækkun eitilfrumna í blóði eftir estrógen-meðferð
Icelandic Medical Journal
CATABOLITE REPRESSIVE EFFECTS OF 5-THIO-D-GLUCOSE ON SACCHAROMYCES-CEREVISIAE
Journal of General Microbiology
Catabolite repressive effects of 5-thio-D-glucose on Saccharomyces cerevisiae.
Journal of General Microbiology
c-myc activation in spontaneous rat immunocytomas containing a 6;7 chromosomal translocation.
Current Topics in Microbiology and Immunology
c-myc activation in spontaneous rat immunocytomas containing a 6;7 chromosomal translocation.
Multiple chromosomal rearrangements in a spontaneously arising t(6;7) rat immunocytoma juxtapose c-myc and immunoglobulin heavy chain sequences
Proceedings of the National Academy of Sciences of the United States of America
C-MYC ACTIVATION IN SPONTANEOUS RAT IMMUNOCYTOMAS CONTAINING A 6-7 CHROMOSOMAL TRANSLOCATION
Current Topics in Microbiology and Immunology
1985
GENE LOCALIZATION ON SORTED CHROMOSOMES - DEFINITIVE EVIDENCE ON THE RELATIVE POSITIONING OF GENES PARTICIPATING IN THE MOUSE PLASMACYTOMA-ASSOCIATED TYPICAL TRANSLOCATION
Proceedings of the National Academy of Sciences of the United States of America
CLONING AND CHARACTERIZATION OF THE DNA-SEQUENCE TRANSPOSED TO THE ONCOGENE C-MYC IN RAT IMMUNOCYTOMAS WITH T(6-7) CHROMOSOMAL TRANSLOCATION
Scandinavian Journal of Immunology
1984
Mælingar á Estrógen- og Prógesterón-viðtökum í Brjóstakrabbameinum
Icelandic Medical Journal
ISOENZYME PATTERN AND SUBCELLULAR-LOCALIZATION OF HEXOKINASES IN HUMAN-BREAST CANCER AND NONPATHOLOGICAL BREAST-TISSUE
International Journal of Cancer
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