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Sigrún Helga Lund - Professor
–
School of Engineering and Natural Sciences
Sigrún Helga Lund
Hún/Hennar
Íslenska
Professor
Location
Tæknigarður / Tg-313
Phone
525 - 4636
Email
sigrunhl [at] hi.is
Unit
Faculty of Physical Sciences
ORCID site
https://orcid.org/0000-0002-3806-2296
Research portal – Sigrún Helga Lund
Courses 2024 - 2025
STÆ203G - Probability and Statistics
STÆ209G - Statistics and Data Analysis
LAN203G - Statistics
MAS201F - Probability and Statistics
STÆ310M - Theory of linear models
STÆ312M - Applied Linear Statistical Models
Education
2014
,
Ph.D.
,
University of Iceland
,
Statistics
2004
,
BS
,
University of Iceland
,
Mathematics
Professional Experience
2018 -
,
Professor,
University of Iceland
2017 -
,
Statistician,
deCODE
2016 -
2018,
Associate Professor,
University of Iceland
2015 -
2016,
Assistant Professor,
University of Iceland
Published works
2024
The correlation between CpG methylation and gene expression is driven by sequence variants
Nature Genetics
Intimate Partner Violence Against Women
Journal of Aggression, Maltreatment and Trauma
Application of ChatGPT for automated problem reframing across academic domains
Computers and Education: Artificial Intelligence
Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid disease
Nature Communications
Erratum to “Application of ChatGPT for automated problem reframing across academic domains” [Computers and Education
Computers and Education: Artificial Intelligence
Variants at the Interleukin 1 Gene Locus and Pericarditis
JAMA Cardiology
Correction to
Nature
Pituitary dysfunction following mild traumatic brain injury in female athletes
Endocrine Connections
2023
Sequence variant affects GCSAML splicing, mast cell specific proteins, and risk of urticaria
Communications Biology
Comparison of medication adherence to different oral anticoagulants
BMJ Open
Association of eGFR and mortality with use of a joint model
Nephrology, dialysis, transplantation
Large-scale plasma proteomics comparisons through genetics and disease associations
Nature
Data from Loss-of-Function Variants in the Tumor-Suppressor Gene <i>PTPN14</i> Confer Increased Cancer Risk
Supplementary Material from Loss-of-Function Variants in the Tumor-Suppressor Gene <i>PTPN14</i> Confer Increased Cancer Risk
Screening for possible hypopituitarism following mild traumatic brain injury: The first all-female study. Who do we need to evaluate further?1
NeuroRehabilitation
Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura
Nature Genetics
Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effect
Annals of the Rheumatic Diseases
Histopathology and levels of proteins in plasma associate with survival after colorectal cancer diagnosis
British Journal of Cancer
Erratum to
NeuroRehabilitation
Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events
JAMA
2022
Warfarin Is Associated With Higher Rates of Upper But Not Lower Gastrointestinal Bleeding Compared with Direct Oral Anticoagulants
Clinical Gastroenterology and Hepatology
Survival, causes of death, and the prognostic role of comorbidities in chronic lymphocytic leukemia in the pre-ibrutinib era: A population-based study
European Journal of Haematology
Comparison of the effectiveness and safety of direct oral anticoagulants
Blood advances
Prevalence, clinical characteristics and outcomes of hypoxic hepatitis in critically ill patients
Scandinavian journal of gastroenterology.
Phenotypic Displays of Cholinergic Enzymes Associate With Markers of Inflammation, Neurofibrillary Tangles, and Neurodegeneration in Pre- and Early Symptomatic Dementia Subjects
Frontiers in Aging Neuroscience
Author Correction
Nature Communications
Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology
Nature Communications
Multiomics study of nonalcoholic fatty liver disease
Nature Genetics
Author Correction: Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology (Nature Communications, (2022), 13, 1, (634), 10.1038/s41467-022-28167-1)
Nature Communications
Cartilage Acidic Protein 1 in Plasma Associates With Prevalent Osteoarthritis and Predicts Future Risk as Well as Progression to Joint Replacements
Arthritis & rheumatology (Hoboken, N.J.)
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Annals of the rheumatic diseases.
Monitoring iron stores in Icelandic blood donors from 1997 through 2019
Transfusion Medicine
Warfarin is associated with higher rates of epistaxis compared to direct oral anticoagulants: A nationwide propensity score-weighted study
Journal of internal medicine
Incidence of and risk factors of chronic kidney disease: results of a nationwide study in Iceland
Clinical Kidney Journal
2021
When does fetal head rotation occur in spontaneous labor at term
American Journal of Obstetrics and Gynecology
Pharmacokinetics of single and repeated oral doses of esomeprazole and gastrin elevation in healthy males and females
Scandinavian Journal of Gastroenterology
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
Cell
Increased risk of inflammatory bowel disease among patients treated with rituximab in Iceland from 2001 to 2018
Scandinavian Journal of Gastroenterology
Autoimmune disease is associated with a lower risk of progression in monoclonal gammopathy of undetermined significance
European Journal of Haematology
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis
Communications Biology
Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor
Communications Biology
Women and intimate partner violence
Scandinavian Journal of Public Health
Large-scale integration of the plasma proteome with genetics and disease
Nature Genetics
Genetic variants associated with platelet count are predictive of human disease and physiological markers
Communications Biology
Fetal descent in nulliparous women assessed by ultrasound
American Journal of Obstetrics and Gynecology
Can ultrasound on admission in active labor predict labor duration and a spontaneous delivery?
American journal of obstetrics & gynecology MFM
High-sensitivity troponins in dialysis patients
Clinical Kidney Journal
Loss-of-function variants in the tumor-suppressor gene PTPN14 confer increased cancer risk
Cancer Research
Predicting the probability of death using proteomics
Communications Biology
Cerebrospinal Fluid C18 Ceramide Associates with Markers of Alzheimer's Disease and Inflammation at the Pre- And Early Stages of Dementia
Journal of Alzheimer's Disease
The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large-Scale Proteomics Scan in Iceland
Arthritis and Rheumatology
Erratum
Cell
Rivaroxaban Is Associated With Higher Rates of Gastrointestinal Bleeding Than Other Direct Oral Anticoagulants
Annals of Internal Medicine
2020
FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid disease
Nature
The prevalence of chronic kidney disease in Iceland according to KDIGO criteria and age-adapted estimated glomerular filtration rate thresholds
Kidney International
Association of glial and neuronal degeneration markers with Alzheimer’s disease cerebrospinal fluid profile and cognitive functions
Alzheimer's Research & Therapy
Predictors of Gastrin Elevation Following Proton Pump Inhibitor Therapy
Journal of Clinical Gastroenterology
Increase in the incidence of alcoholic pancreatitis and alcoholic liver disease in Iceland: impact of per capita alcohol consumption
Scandinavian Journal of Gastroenterology
Abstinence from alcohol and alcohol rehabilitation therapy in alcoholic liver disease
Scandinavian Journal of Gastroenterology
Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank
Communications Biology
Long-term Outcome of Implantable Cardioverter/Defibrillator Lead Failure
JAMA Internal Medicine
A nationwide study on hepatocellular carcinoma
Cancer Epidemiology
High Mortality from Major Vascular Trauma in Traffic Accidents
Scandinavian Journal of Surgery
Use of proton pump inhibitors and mortality among Icelandic patients with prostate cancer
Basic and Clinical Pharmacology and Toxicology
Suicide rates in Iceland before and after the 2008 Global Recession
European Journal of Public Health
2019
Computerized algorithms compared with a nephrologist's diagnosis of acute kidney injury in the emergency department
European Journal of Internal Medicine
The mother’s risk of premature death after child loss across two centuries
eLife
Biochemical response to ursodeoxycholic acid among PBC patients
Scandinavian Journal of Gastroenterology
Proton pump inhibitor use and risk of breast cancer, prostate cancer, and malignant melanoma
Pharmacoepidemiology and Drug Safety
A pleasant experience of peer evaluation in statistical education
Tímarit Kennslumiðstöðvar Háskóla Íslands
Parental longevity and survival among patients with multiple myeloma and monoclonal gammopathy of undetermined significance
British Journal of Haematology
Ara h 1 and Ara h 6 Sensitization Causes Clinical Peanut Allergy in Ara h 2-Negative Individuals
International Archives of Allergy and Immunology
GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures.
Nature Communications
2018
Physical activity may decrease the likelihood of children developing constipation
Acta Paediatrica, International Journal of Paediatrics
Oncoplastic Breast-Conserving Surgery in Iceland: A Population-Based Study
Scandinavian Journal of Surgery
La asociación de diferentes eventos traumáticos vitales y suicidalidad
European Journal of Psychotraumatology
Proton-pump inhibitors among adults
Therapeutic Advances in Gastroenterology
Dietary intake is associated with risk of multiple myeloma and its precursor disease
PLoS ONE
Variations in elderly peoples’ visits to the emergency departments in Iceland
International Emergency Nursing
Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis
Nature Genetics
Views of Icelandic women towards genetic counseling - and testing of BRCA2 mutations
Laeknabladid
The association between different traumatic life events and suicidality.
European Journal of Psychotraumatology
The SHA2PE score: a new score for lower gastrointestinal bleeding that predicts low-risk of hospital-based intervention.
Scandinavian Journal of Gastroenterology
Viðhorf íslenskra kvenna til erfðaráðgjafar og erfðaprófa á BRCA1 og BRCA2 stökkbreytingum
Læknablaðið
The SHA
2
PE score
Scandinavian Journal of Gastroenterology
The association between different traumatic life events and suicidality
European Journal of Psychotraumatology
2017
Editor's Choice- Diagnosis of type 2 diabetes and prediabetes among patients with acute coronary syndromes
European heart journal. Acute cardiovascular care
Greiningarferli lungnakrabbameins á landspítala
Laeknabladid
Greiningarferli lungnakrabbameins á landspítala
Læknablaðið
Suicide attempts and self-harm during a dramatic national economic transition
European Journal of Public Health
Bone disease in monoclonal gammopathy of undetermined significance
Blood advances
The impact of prior malignancies on second malignancies and survival in MM patients
Blood advances
History of autoimmune disease is associated with impaired survival in multiple myeloma and monoclonal gammopathy of undetermined significance
Annals of Hematology
Fast diagnostic track for suspected lung cancer: A patient centered approach
Laeknabladid
Obesity and risk of monoclonal gammopathy of undetermined significance and progression to multiple myeloma
Blood advances
Regional differences in mortality, hospital discharges and primary care contacts for cardiovascular disease
Scandinavian Journal of Public Health
Study of Gender Differences in Proton Pump Inhibitor Dose Requirements for GERD
Journal of Clinical Gastroenterology
A population-based study on epidemiology of intensive care unit treated traumatic brain injury in Iceland
Acta Anaesthesiologica Scandinavica
Reduced anticoagulation variability in patients on warfarin monitored with Fiix-prothrombin time associates with reduced thromboembolism
Journal of Thrombosis and Thrombolysis
Study of Gender Differences in Proton Pump Inhibitor Dose Requirements for GERD A Double-Blind Randomized Trial
Journal of Clinical Gastroenterology
2016
Survival in multiple myeloma patients who develop second malignancies
Haematologica
Risk of Progression in Monoclonal Gammopathy of Undetermined Significance (MGUS): Results from a Population-Based Screening Study
Blood
Warfarin as a new oral anticoagulant agent?
Journal of Thrombosis and Haemostasis
Diagnosis of type 2 diabetes and prediabetes among patients with acute coronary syndromes
European Heart Journal: Acute Cardiovascular Care
Faraldsfræði tveggja Laurén-flokka kirtilfrumukrabbameina í maga á Íslandi árin 1990-2009
Læknablaðið
Dialysis modality and nutritional status are associated with variability of inflammatory markers.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Association between Daily Hydrogen Sulfide Exposure and Incidence of Emergency Hospital Visits: A Population-Based Study
PLoS ONE
Individualised risk assessment for diabetic retinopathy and optimisation of screening intervals
British Journal of Ophthalmology
The incidence and mortality of acute thoracic aortic dissection
European Journal of Cardio-thoracic Surgery
Free fatty acid suppositories are as effective as docusate sodium and sorbitol enemas in treating constipation in children
Acta Paediatrica, International Journal of Paediatrics
Fiix-prothrombin time monitoring improves warfarin anticoagulation outcome in atrial fibrillation
International Journal of Laboratory Hematology
Epidemiology of the two types of gastric adenocarcinoma in Iceland according to the Laurén histological classification 1990-2009,Faraldsfrædi tveggja flokka kirtilfrumukrabbameina í maga á Íslandi samkvæmt vefjaflokkunarkerfi Laurén árin 1990-2009
Laeknabladid
Improved Survival in AL Amyloidosis: A Population-Based Study on 1,430 Patients Diagnosed in Sweden 1995-2013
Blood
2015
Maternal geographic residence, local health service supply and birth outcomes
Acta Obstetricia et Gynecologica Scandinavica
Fiix-prothrombin time versus standard prothrombin time for monitoring of warfarin anticoagulation
The Lancet Haematology
Survival in patients with familial and sporadic myeloproliferative neoplasms
Blood
Smoking and obesity among pregnant women in Iceland 2001-2010
European Journal of Public Health
The role of diagnosis and clinical follow-up of monoclonal gammopathy of undetermined significance on survival in multiple myeloma
JAMA Oncology
Healing rate and autoimmune safety of full-thickness wounds treated with fish skin acellular dermal matrix versus porcine small-intestine submucosa: a noninferiority study.
The international journal of lower extremity wounds
Vitamin D and Glucose Regulation in Icelandic Patients with Acute Coronary Syndrome
Cardiology
The effect of SNPs on expression levels in Nimblegen RNA expression microarrays
International Journal of Data Mining and Bioinformatics
Information Technology and Diabetic Eye Screening: Validation, Patient Education, and Economic Impact
Diabetes
Clinical trial: free fatty acid suppositories compared with enema as bowel preparation for flexible sigmoidoscopy.
Frontline Gastroenterology
Hodgkin lymphoma risk following infectious and chronic inflammatory diseases: a large population-based case-control study from Sweden
International Journal of Hematology
Population-based study on the impact of the familial form of Waldenstrom macroglobulinemia on overall survival
Blood
Topical dexamethasone γ-cyclodextrin nanoparticle eye drops increase visual acuity and decrease macular thickness in diabetic macular oedema
Acta Ophthalmologica
Pregnancy-induced hypertensive disorders before and after a national economic collapse
PLoS ONE
2014
Emergency department visits and revisits by elderly people 2008-2012 in Iceland
International Emergency Nursing
A method for detecting long non-coding RNAs with tiled RNA expression microarrays
PLoS ONE
Validation of a model to estimate personalised screening frequency to monitor diabetic retinopathy
Diabetologia
Dorzolamide cyclodextrin nanoparticle suspension eye drops and trusopt in rabbit
Journal of Ocular Pharmacology and Therapeutics
Monitoring Warfarin with the Fiix-Prothrombin Time Improves Anticoagulation Stability and Long-Term Clinical Outcome. the Fiix-Trial
Blood
Kinetics of γ-cyclodextrin nanoparticle suspension eye drops in tear fluid
Acta Ophthalmologica
Long term follow-up and liver-related death rate in patients with non-alcoholic and alcoholic related fatty liver disease
BMC Gastroenterology
Obesity and Risk of Monoclonal Gammopathy of Undetermined Significance: A Population-Based Study
Blood
Patterns of Infectious Morbidity in Patients with Waldenstrom's Macroglobulinaemia/Lymphoplasmacytic Lymphoma: A Population-Based Study
Blood
2013
Multiple Myeloma Patients With Prior Knowledge Of MGUS Have a Better Survival Compared To Multiple Myeloma Patients Without Prior Knowledge Of MGUS
Blood
Impact Of History Of Autoimmune Disease On Survival In Multiple Myeloma Monoclonal Gammopathy Of Undetermined Significance: A Population-Based Study
Blood
Bone Marrow Fibrosis In Patients With Multiple Myeloma: A New Prognostic Factor For Survival?
Blood
2009
Identification and classification of expressed RNA probes in microarray experiments
Joint Statistical Meetings (JSM) proceedings, Biometrics Section
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