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Forsíða

Sigrún Helga Lund - Professor

Sigrún Helga Lund

–

School of Engineering and Natural Sciences

Sigrún Helga LundHún/Hennar

Professor

Location
Tæknigarður / Tg-313
Phone
525 - 4636
Email
sigrunhl [at] hi.is

Unit
Faculty of Physical Sciences

Published works

2024

Application of ChatGPT for automated problem reframing across academic domainsComputers and Education: Artificial Intelligence
Correction toNature
Pituitary dysfunction following mild traumatic brain injury in female athletesEndocrine Connections
Erratum to “Application of ChatGPT for automated problem reframing across academic domains” [Computers and EducationComputers and Education: Artificial Intelligence
The correlation between CpG methylation and gene expression is driven by sequence variantsNature Genetics
Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid diseaseNature Communications
Intimate Partner Violence Against WomenJournal of Aggression, Maltreatment and Trauma
Variants at the Interleukin 1 Gene Locus and PericarditisJAMA Cardiology

2023

Screening for possible hypopituitarism following mild traumatic brain injury: The first all-female study. Who do we need to evaluate further?1NeuroRehabilitation
Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without auraNature Genetics
Large-scale plasma proteomics comparisons through genetics and disease associationsNature
Association of eGFR and mortality with use of a joint modelNephrology, dialysis, transplantation
Supplementary Material from Loss-of-Function Variants in the Tumor-Suppressor Gene <i>PTPN14</i> Confer Increased Cancer Risk
Data from Loss-of-Function Variants in the Tumor-Suppressor Gene <i>PTPN14</i> Confer Increased Cancer Risk
Histopathology and levels of proteins in plasma associate with survival after colorectal cancer diagnosisBritish Journal of Cancer
Erratum toNeuroRehabilitation
Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular EventsJAMA
Sequence variant affects GCSAML splicing, mast cell specific proteins, and risk of urticariaCommunications Biology
Comparison of medication adherence to different oral anticoagulantsBMJ Open
Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effectAnnals of the Rheumatic Diseases

2022

Cartilage Acidic Protein 1 in Plasma Associates With Prevalent Osteoarthritis and Predicts Future Risk as Well as Progression to Joint ReplacementsArthritis & rheumatology (Hoboken, N.J.)
Warfarin is associated with higher rates of epistaxis compared to direct oral anticoagulants: A nationwide propensity score-weighted studyJournal of internal medicine
Author CorrectionNature Communications
Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathologyNature Communications
Author Correction: Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology (Nature Communications, (2022), 13, 1, (634), 10.1038/s41467-022-28167-1)Nature Communications
Monitoring iron stores in Icelandic blood donors from 1997 through 2019Transfusion Medicine
Prevalence, clinical characteristics and outcomes of hypoxic hepatitis in critically ill patientsScandinavian journal of gastroenterology.
Comparison of the effectiveness and safety of direct oral anticoagulantsBlood advances
Survival, causes of death, and the prognostic role of comorbidities in chronic lymphocytic leukemia in the pre-ibrutinib era: A population-based studyEuropean Journal of Haematology
Multiomics study of nonalcoholic fatty liver diseaseNature Genetics
Warfarin Is Associated With Higher Rates of Upper But Not Lower Gastrointestinal Bleeding Compared with Direct Oral AnticoagulantsClinical Gastroenterology and Hepatology
Phenotypic Displays of Cholinergic Enzymes Associate With Markers of Inflammation, Neurofibrillary Tangles, and Neurodegeneration in Pre- and Early Symptomatic Dementia SubjectsFrontiers in Aging Neuroscience
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subsetAnnals of the rheumatic diseases.
Incidence of and risk factors of chronic kidney disease: results of a nationwide study in IcelandClinical Kidney Journal

2021

Can ultrasound on admission in active labor predict labor duration and a spontaneous delivery?American journal of obstetrics & gynecology MFM
ErratumCell
The CRTAC1 Protein in Plasma Is Associated With Osteoarthritis and Predicts Progression to Joint Replacement: A Large-Scale Proteomics Scan in IcelandArthritis and Rheumatology
Predicting the probability of death using proteomicsCommunications Biology
Autoimmune disease is associated with a lower risk of progression in monoclonal gammopathy of undetermined significanceEuropean Journal of Haematology
Cerebrospinal Fluid C18 Ceramide Associates with Markers of Alzheimer's Disease and Inflammation at the Pre- And Early Stages of DementiaJournal of Alzheimer's Disease
Increased risk of inflammatory bowel disease among patients treated with rituximab in Iceland from 2001 to 2018Scandinavian Journal of Gastroenterology
Genetic variants associated with platelet count are predictive of human disease and physiological markersCommunications Biology
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasisCommunications Biology
Large-scale integration of the plasma proteome with genetics and diseaseNature Genetics
Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptorCommunications Biology
Women and intimate partner violenceScandinavian Journal of Public Health
Fetal descent in nulliparous women assessed by ultrasoundAmerican Journal of Obstetrics and Gynecology
Rivaroxaban Is Associated With Higher Rates of Gastrointestinal Bleeding Than Other Direct Oral AnticoagulantsAnnals of Internal Medicine
High-sensitivity troponins in dialysis patientsClinical Kidney Journal
Pharmacokinetics of single and repeated oral doses of esomeprazole and gastrin elevation in healthy males and femalesScandinavian Journal of Gastroenterology
When does fetal head rotation occur in spontaneous labor at termAmerican Journal of Obstetrics and Gynecology
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populationsCell
Loss-of-function variants in the tumor-suppressor gene PTPN14 confer increased cancer riskCancer Research

2020

Increase in the incidence of alcoholic pancreatitis and alcoholic liver disease in Iceland: impact of per capita alcohol consumptionScandinavian Journal of Gastroenterology
A nationwide study on hepatocellular carcinomaCancer Epidemiology
Use of proton pump inhibitors and mortality among Icelandic patients with prostate cancerBasic and Clinical Pharmacology and Toxicology
Long-term Outcome of Implantable Cardioverter/Defibrillator Lead FailureJAMA Internal Medicine
Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK BiobankCommunications Biology
Abstinence from alcohol and alcohol rehabilitation therapy in alcoholic liver diseaseScandinavian Journal of Gastroenterology
High Mortality from Major Vascular Trauma in Traffic AccidentsScandinavian Journal of Surgery
FLT3 stop mutation increases FLT3 ligand level and risk of autoimmune thyroid diseaseNature
Association of glial and neuronal degeneration markers with Alzheimer’s disease cerebrospinal fluid profile and cognitive functionsAlzheimer's Research & Therapy
Predictors of Gastrin Elevation Following Proton Pump Inhibitor TherapyJournal of Clinical Gastroenterology
Suicide rates in Iceland before and after the 2008 Global RecessionEuropean Journal of Public Health
The prevalence of chronic kidney disease in Iceland according to KDIGO criteria and age-adapted estimated glomerular filtration rate thresholdsKidney International

2019

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures.Nature Communications
Ara h 1 and Ara h 6 Sensitization Causes Clinical Peanut Allergy in Ara h 2-Negative IndividualsInternational Archives of Allergy and Immunology
The mother’s risk of premature death after child loss across two centurieseLife
Computerized algorithms compared with a nephrologist's diagnosis of acute kidney injury in the emergency departmentEuropean Journal of Internal Medicine
Biochemical response to ursodeoxycholic acid among PBC patientsScandinavian Journal of Gastroenterology
Parental longevity and survival among patients with multiple myeloma and monoclonal gammopathy of undetermined significanceBritish Journal of Haematology
Proton pump inhibitor use and risk of breast cancer, prostate cancer, and malignant melanomaPharmacoepidemiology and Drug Safety
A pleasant experience of peer evaluation in statistical educationTímarit Kennslumiðstöðvar Háskóla Íslands

2018

The association between different traumatic life events and suicidality.European Journal of Psychotraumatology
Proton-pump inhibitors among adultsTherapeutic Advances in Gastroenterology
Variations in elderly peoples’ visits to the emergency departments in IcelandInternational Emergency Nursing
Dietary intake is associated with risk of multiple myeloma and its precursor diseasePLoS ONE
Physical activity may decrease the likelihood of children developing constipationActa Paediatrica, International Journal of Paediatrics
Views of Icelandic women towards genetic counseling - and testing of BRCA2 mutationsLaeknabladid
The SHA2PE score: a new score for lower gastrointestinal bleeding that predicts low-risk of hospital-based intervention.Scandinavian Journal of Gastroenterology
Oncoplastic Breast-Conserving Surgery in Iceland: A Population-Based StudyScandinavian Journal of Surgery
Viðhorf íslenskra kvenna til erfðaráðgjafar og erfðaprófa á BRCA1 og BRCA2 stökkbreytingumLæknablaðið
The SHA ₂ PE scoreScandinavian Journal of Gastroenterology
La asociación de diferentes eventos traumáticos vitales y suicidalidadEuropean Journal of Psychotraumatology
The association between different traumatic life events and suicidalityEuropean Journal of Psychotraumatology
Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritisNature Genetics

2017

A population-based study on epidemiology of intensive care unit treated traumatic brain injury in IcelandActa Anaesthesiologica Scandinavica
Editor's Choice- Diagnosis of type 2 diabetes and prediabetes among patients with acute coronary syndromesEuropean heart journal. Acute cardiovascular care
History of autoimmune disease is associated with impaired survival in multiple myeloma and monoclonal gammopathy of undetermined significanceAnnals of Hematology
Study of Gender Differences in Proton Pump Inhibitor Dose Requirements for GERDJournal of Clinical Gastroenterology
Reduced anticoagulation variability in patients on warfarin monitored with Fiix-prothrombin time associates with reduced thromboembolismJournal of Thrombosis and Thrombolysis
Bone disease in monoclonal gammopathy of undetermined significanceBlood advances
Greiningarferli lungnakrabbameins á landspítalaLaeknabladid
Suicide attempts and self-harm during a dramatic national economic transitionEuropean Journal of Public Health
Fast diagnostic track for suspected lung cancer: A patient centered approachLaeknabladid
Greiningarferli lungnakrabbameins á landspítalaLæknablaðið
Regional differences in mortality, hospital discharges and primary care contacts for cardiovascular diseaseScandinavian Journal of Public Health
The impact of prior malignancies on second malignancies and survival in MM patientsBlood advances
Study of Gender Differences in Proton Pump Inhibitor Dose Requirements for GERD A Double-Blind Randomized TrialJournal of Clinical Gastroenterology
Obesity and risk of monoclonal gammopathy of undetermined significance and progression to multiple myelomaBlood advances

2016

Faraldsfræði tveggja Laurén-flokka kirtilfrumukrabbameina í maga á Íslandi árin 1990-2009Læknablaðið
Survival in multiple myeloma patients who develop second malignanciesHaematologica
Epidemiology of the two types of gastric adenocarcinoma in Iceland according to the Laurén histological classification 1990-2009,Faraldsfrædi tveggja flokka kirtilfrumukrabbameina í maga á Íslandi samkvæmt vefjaflokkunarkerfi Laurén árin 1990-2009Laeknabladid
Improved Survival in AL Amyloidosis: A Population-Based Study on 1,430 Patients Diagnosed in Sweden 1995-2013Blood
Warfarin as a new oral anticoagulant agent?Journal of Thrombosis and Haemostasis
Dialysis modality and nutritional status are associated with variability of inflammatory markers.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Individualised risk assessment for diabetic retinopathy and optimisation of screening intervalsBritish Journal of Ophthalmology
The incidence and mortality of acute thoracic aortic dissectionEuropean Journal of Cardio-thoracic Surgery
Association between Daily Hydrogen Sulfide Exposure and Incidence of Emergency Hospital Visits: A Population-Based StudyPLoS ONE
Fiix-prothrombin time monitoring improves warfarin anticoagulation outcome in atrial fibrillationInternational Journal of Laboratory Hematology
Free fatty acid suppositories are as effective as docusate sodium and sorbitol enemas in treating constipation in childrenActa Paediatrica, International Journal of Paediatrics
Risk of Progression in Monoclonal Gammopathy of Undetermined Significance (MGUS): Results from a Population-Based Screening StudyBlood
Diagnosis of type 2 diabetes and prediabetes among patients with acute coronary syndromesEuropean Heart Journal: Acute Cardiovascular Care

2015

Hodgkin lymphoma risk following infectious and chronic inflammatory diseases: a large population-based case-control study from SwedenInternational Journal of Hematology
Smoking and obesity among pregnant women in Iceland 2001-2010European Journal of Public Health
Survival in patients with familial and sporadic myeloproliferative neoplasmsBlood
Topical dexamethasone γ-cyclodextrin nanoparticle eye drops increase visual acuity and decrease macular thickness in diabetic macular oedemaActa Ophthalmologica
Fiix-prothrombin time versus standard prothrombin time for monitoring of warfarin anticoagulationThe Lancet Haematology
Maternal geographic residence, local health service supply and birth outcomesActa Obstetricia et Gynecologica Scandinavica
Pregnancy-induced hypertensive disorders before and after a national economic collapsePLoS ONE
Information Technology and Diabetic Eye Screening: Validation, Patient Education, and Economic ImpactDiabetes
Vitamin D and Glucose Regulation in Icelandic Patients with Acute Coronary SyndromeCardiology
Clinical trial: free fatty acid suppositories compared with enema as bowel preparation for flexible sigmoidoscopy.Frontline Gastroenterology
The effect of SNPs on expression levels in Nimblegen RNA expression microarraysInternational Journal of Data Mining and Bioinformatics
Healing rate and autoimmune safety of full-thickness wounds treated with fish skin acellular dermal matrix versus porcine small-intestine submucosa: a noninferiority study.The international journal of lower extremity wounds
The role of diagnosis and clinical follow-up of monoclonal gammopathy of undetermined significance on survival in multiple myelomaJAMA Oncology
Population-based study on the impact of the familial form of Waldenstrom macroglobulinemia on overall survivalBlood

2014

Long term follow-up and liver-related death rate in patients with non-alcoholic and alcoholic related fatty liver diseaseBMC Gastroenterology
Emergency department visits and revisits by elderly people 2008-2012 in IcelandInternational Emergency Nursing
Monitoring Warfarin with the Fiix-Prothrombin Time Improves Anticoagulation Stability and Long-Term Clinical Outcome. the Fiix-TrialBlood
Kinetics of γ-cyclodextrin nanoparticle suspension eye drops in tear fluidActa Ophthalmologica
Validation of a model to estimate personalised screening frequency to monitor diabetic retinopathyDiabetologia
Obesity and Risk of Monoclonal Gammopathy of Undetermined Significance: A Population-Based StudyBlood
Patterns of Infectious Morbidity in Patients with Waldenstrom's Macroglobulinaemia/Lymphoplasmacytic Lymphoma: A Population-Based StudyBlood
A method for detecting long non-coding RNAs with tiled RNA expression microarraysPLoS ONE
Dorzolamide cyclodextrin nanoparticle suspension eye drops and trusopt in rabbitJournal of Ocular Pharmacology and Therapeutics

2013

Impact Of History Of Autoimmune Disease On Survival In Multiple Myeloma Monoclonal Gammopathy Of Undetermined Significance: A Population-Based StudyBlood
Bone Marrow Fibrosis In Patients With Multiple Myeloma: A New Prognostic Factor For Survival?Blood
Multiple Myeloma Patients With Prior Knowledge Of MGUS Have a Better Survival Compared To Multiple Myeloma Patients Without Prior Knowledge Of MGUSBlood

2009

Identification and classification of expressed RNA probes in microarray experiments Joint Statistical Meetings (JSM) proceedings, Biometrics Section

Keywords for Specialisation:

Applied statistics