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Þorsteinn Loftsson - Professor Emeritus

Þorsteinn Loftsson

–

Heilbrigðisvísindasvið

Þorsteinn Loftsson

Professor Emeritus

Location
Hagi / Ha-313
Phone
525 - 4464
Email
thorstlo [at] hi.is

Unit
Faculty of Pharmaceutical Sciences
Published Work
Þorsteinn Loftsson - published work

Curriculum Vitae
Þorsteinn Loftsson - Curriculum Vitae
ORCID site
https://orcid.org/0000-0002-9439-1553
Research portal – Þorsteinn Loftsson

Published works

2023

Topical dexamethasone delivery to the retina: An aqueous cyclodextrin-based microsuspensionJournal of Drug Delivery Science and Technology
Voriconazole Eye Drops: Enhanced Solubility and Stability through Ternary Voriconazole/Sulfobutyl Ether β-Cyclodextrin/Polyvinyl Alcohol ComplexesInternational Journal of Molecular Sciences
Tacrolimus/hydroxypropyl-β-cyclodextrin-loaded nanoemulsions stabilized by Zein-Soluplus® nanoparticles for retinal diseasesJournal of Drug Delivery Science and Technology
Celecoxib/Cyclodextrin Eye Drop Microsuspensions: Evaluation of In Vitro Cytotoxicity and Anti-VEGF Efficacy for Retinal DiseasesPharmaceutics
Anomalous Properties of Cyclodextrins and Their Complexes in Aqueous SolutionsMaterials

2022

A Current Overview of Cyclodextrin-Based Nanocarriers for Enhanced Antifungal DeliveryPharmaceuticals
Stabilization and solubilization of difluprednate in aqueous cyclodextrin solution and its characterization for ophthalmic deliveryJournal of Drug Delivery Science and Technology
Aqueous eye drops containing drug/cyclodextrin nanoparticles deliver therapeutic drug concentrations to both anterior and posterior segmentActa Ophthalmologica
Aqueous Prostaglandin Eye Drop FormulationsPharmaceutics
Structural Characterization Study of a Lipid Nanocapsule Formulation Intended for Drug Delivery Applications Using Small-Angle Scattering TechniquesMolecular Pharmaceutics
Physicochemical and Stability Evaluation of Topical Niosomal Encapsulating Fosinopril/γ-Cyclodextrin Complex for Ocular DeliveryPharmaceutics
Development of Fenofibrate/Randomly Methylated β-Cyclodextrin-Loaded Eudragit® RL 100 Nanoparticles for Ocular DeliveryMolecules
Effect of salt formation on γ-cyclodextrin solubilization of irbesartan and candesartan and the chemical stability of their ternary complexesJournal of Drug Delivery Science and Technology
Cyclodextrins and Drug Membrane Permeation: Thermodynamic ConsiderationsJournal of Pharmaceutical Sciences

2021

Cytotoxicity of β-Cyclodextrins in Retinal Explants for Intravitreal Drug FormulationsMolecules
1,4-Benzodiazepines: Chemical stability and cyclodextrin solubilizationJournal of Drug Delivery Science and Technology
Bio-Distribution and Pharmacokinetics of Topically Administered γ-Cyclodextrin Based Eye Drops in RabbitsPharmaceuticals

2020

Stability characterization, kinetics and mechanism of tacrolimus degradation in cyclodextrin solutionsInternational Journal of Pharmaceutics
Effect of porcine pancreatic α-amylase on dexamethasone release from aqueous solution containing natural γ-cyclodextrinInternational Journal of Pharmaceutics
Characterization and Evaluation of Ternary Complexes of Ascorbic Acid with γ-Cyclodextrin and Poly(vinyl Alcohol)International Journal of Molecular Sciences
In Vitro and Ex Vivo Evaluation of Nepafenac-Based Cyclodextrin Microparticles for Treatment of Eye InflammationNanomaterials
Antifungal activity of econazole nitrate/cyclodextrin complex: Effect of pH and formation of complex aggregatesInternational Journal of Pharmaceutics

2019

Interaction of Native Cyclodextrins and Their Hydroxypropylated Derivatives with Carbamazepine in Aqueous Solution. Evaluation of Inclusion Complexes and Aggregates FormationACS Omega
Self-association of cyclodextrins and cyclodextrin complexes in aqueous solutionsInternational Journal of Pharmaceutics
Drug delivery to retinal photoreceptorsDrug Discovery Today
Nepafenac-Loaded Cyclodextrin/Polymer Nanoaggregates: A New Approach to Eye Drop FormulationMaterials
Cyclodextrin–Amphiphilic Copolymer Supramolecular Assemblies for the Ocular Delivery of NatamycinNanomaterials

2018

Solubility of Cyclodextrins and Drug/Cyclodextrin ComplexesMolecules
Disruption of α- and γ-cyclodextrin aggregates promoted by chaotropic agent (urea)Journal of Drug Delivery Science and Technology
Self-assembled cyclodextrin-based nanoparticles for meropenem stabilizationJournal of Drug Delivery Science and Technology
Novel excipients – Regulatory challenges and perspectives – The EU insightInternational Journal of Pharmaceutics
Topical drug delivery to the posterior segment of the eye: Dexamethasone concentrations in various eye tissues after topical administration for up to 15 days to rabbitsJournal of Drug Delivery Science and Technology
Topical drug delivery to the posterior segment of the eye: The effect of benzalkonium chloride on topical dexamethasone penetration into the eye in vivoJournal of Drug Delivery Science and Technology
2-Hydroxypropyl-β-Cyclodextrin Aggregates: Identification and Development of Analytical TechniquesMaterials

2015

Formation and stability assessment of self-assembled nanoparticles from large Mw chitosan and sulfobutylether-β-cyclodextrinJournal of Drug Delivery Science and Technology

2013

Triclosan-loaded with high encapsulation efficiency into PLA nanoparticles coated with β-cyclodextrin polymerJournal of Inclusion Phenomena and Macrocyclic Chemistry
Encapsulation of drug molecules into Calix[n]arene Nanobaskets. Role of Aminocalix[n]arenes in biopharmaceutical fieldJournal of Pharmaceutical Sciences
Dextran-based cyclodextrin polymers: Their solubilizing effect and self-associationCarbohydrate Polymers
A permeation method for detection of self-aggregation of doxorubicin in aqueous environmentInternational Journal of Pharmaceutics
For the special IJP issue "Poorly soluble drugs"International Journal of Pharmaceutics
Physicochemical characterization and stability of microbeads containing cod-liver oil encircled with natural cyclodextrinsJournal of Inclusion Phenomena and Macrocyclic Chemistry
Antifungal drug solubilizing activity and self-aggregation ability of cationic aminocalix[4]arene in comparison to SBEβCD: effect of addition of water-soluble polymerJournal of Inclusion Phenomena and Macrocyclic Chemistry
Dexamethasone eye drops containing γ-cyclodextrin-based nanogelsInternational Journal of Pharmaceutics
CyclodextrinsInternational Journal of Pharmaceutics

2012

Cross-linked hydroxypropyl-β-cyclodextrin and γ-cyclodextrin nanogels for drug delivery: Physicochemical and loading/release propertiesCarbohydrate Polymers
Cyclodextrin-based nanogels for pharmaceutical and biomedical applicationsInternational Journal of Pharmaceutics
Drug permeation through biomembranes: Cyclodextrins and the unstirred water layerPharmazie
Clinical trial: Marine lipid suppositories as laxativesMarine Drugs
Cyclodextrins as functional excipients: Methods to enhance complexation efficiencyJournal of Pharmaceutical Sciences
Topical drug delivery to the eye: DorzolamideActa Ophthalmologica
The effect of parenterally administered cyclodextrins on the pharmacokinetics of coadministered drugsJournal of Pharmaceutical Sciences
Self-assembly of cyclodextrins: Formation of cyclodextrin polymer based nanoparticlesJournal of Drug Delivery Science and Technology

2011

Self-assembly of cyclodextrin complexes: Aggregation of hydrocortisone/cyclodextrin complexesInternational Journal of Pharmaceutics
Self-assembly of cyclodextrins: The effect of the guest moleculeInternational Journal of Pharmaceutics
Drug loading in cyclodextrin polymers: Dexamethasone model drugJournal of Inclusion Phenomena and Macrocyclic Chemistry
Drug/cyclodextrin: Beyond inclusion complexationJournal of Inclusion Phenomena and Macrocyclic Chemistry
Pharmaceutical applications of cyclodextrins: Effects on drug permeation through biological membranesJournal of Pharmacy and Pharmacology
Evaluation of sugammadex self-associationInternational Journal of Pharmaceutics
Preface: First European cyclodextrin conferenceJournal of Inclusion Phenomena and Macrocyclic Chemistry
Topical dexamethasone-cyclodextrin microparticle eye drops for diabetic macular edemaInvestigative Ophthalmology and Visual Science
Self-assembly of cyclodextrin complexes: Effect of temperature, agitation and media composition on aggregationInternational Journal of Pharmaceutics

2010

Enalaprilat and enalapril maleate eyedrops lower intraocular pressure in rabbitsActa Ophthalmologica
Evaluation of a cationic calix[4]arene: Solubilization and self-aggregation abilityInternational Journal of Pharmaceutics
Effects of cogrinding with β-cyclodextrin on the solid state fentanylJournal of Pharmaceutical Sciences
Pharmaceutical applications of cyclodextrins: Basic science and product developmentJournal of Pharmacy and Pharmacology
Solubility and permeability of steroids in water in the presence of potassium halidesPharmazie
γCD/HPγCD mixtures as solubilizer: Solid-state characterization and sample dexamethasone eye drop suspensionJournal of Pharmacy and Pharmaceutical Sciences
Cyclodextrin solubilization of carbonic anhydrase inhibitor drugs: Formulation of dorzolamide eye drop microparticle suspensionEuropean Journal of Pharmaceutics and Biopharmaceutics
Parenteral delivery of HPβCD: Effects on drug-HSA bindingAAPS PharmSciTech
Aqueous solubility and true solutionsPharmazie
γ-Cyclodextrin hydrogels and semi-interpenetrating networks for sustained delivery of dexamethasoneCarbohydrate Polymers
Effect of self-aggregation of γ-cyclodextrin on drug solubilizationJournal of Inclusion Phenomena and Macrocyclic Chemistry
Self-assembled cyclodextrin aggregates and nanoparticlesInternational Journal of Pharmaceutics
Cyclodextrins as solubilizers: Formation of complex aggregatesJournal of Pharmaceutical Sciences
Studies of curcumin and curcuminoids. XXXVI. The stoichiometry and complexation constants of cyclodextrin complexes as determined by the phase-solubility method and UV-Vis titrationJournal of Inclusion Phenomena and Macrocyclic Chemistry

2009

Drug targeting to the hair follicles: A cyclodextrin-based drug deliveryAAPS PharmSciTech
Cyclodextrins and their use in pharmacy and cosmetology | Les cyclodextrines et leurs utilisations en pharmacie et cosmétologieS.T.P. Pharma Pratiques
Fish skin as a model membrane: Structure and characteristicsJournal of Pharmacy and Pharmacology
Diffusion characteristics of vitreous humour and saline solution follow the Stokes Einstein equationGraefe's Archive for Clinical and Experimental Ophthalmology
CDs as solubilizers: Effects of excipients and competing drugsInternational Journal of Pharmaceutics
Crystal structure of fentanyl baseX-ray Structure Analysis Online

2008

Topical drug delivery to the posterior segment of the eye: Anatomical and physiological considerationsPharmazie
Comparative interaction of 2-hydroxypropyl-β-cyclodextrin and sulfobutylether-β-cyclodextrin with itraconazole: Phase-solubility behavior and stabilization of supersaturated drug solutionsEuropean Journal of Pharmaceutical Sciences
Carvedilol: Solubilization and cyclodextrin complexation: A technical noteAAPS PharmSciTech
Physicochemical properties of water and its effect on drug delivery. A commentaryInternational Journal of Pharmaceutics
γCD/HPγCD: Synergistic solubilizationInternational Journal of Pharmaceutics

2007

Development of octanol membranes for drug screeningJournal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrins and their pharmaceutical applicationsInternational Journal of Pharmaceutics
Cyclodextrins and the liquid-liquid phase distribution of progesterone, estrone and prednicarbateJournal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrins as pharmaceutical solubilizersAdvanced Drug Delivery Reviews
Effects of various cyclodextrins on the stability of freeze-dried lactate dehydrogenaseJournal of Pharmaceutical Sciences
Effects of cyclodextrins on drug delivery through biological membranesJournal of Pharmaceutical Sciences
Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrinsInternational Journal of Pharmaceutics
Topical and systemic absorption in delivery of dexamethasone to the anterior and posterior segments of the eyeActa Ophthalmologica Scandinavica
Studies on curcumin and curcuminoids. XXXI. Symmetric and asymmetric curcuminoids: Stability, activity and complexation with cyclodextrinInternational Journal of Pharmaceutics
Antibacterial activity of methylated chitosan and chitooligomer derivatives: Synthesis and structure activity relationshipsEuropean Polymer Journal
Cyclodextrin microparticles for drug delivery to the posterior segment of the eye: Aqueous dexamethasone eye dropsJournal of Pharmacy and Pharmacology
Dexamethasone delivery to posterior segment of the eyeJournal of Inclusion Phenomena and Macrocyclic Chemistry
The complexation efficiencyJournal of Inclusion Phenomena and Macrocyclic Chemistry
Cyclodextrins in ocular drug delivery: Theoretical basis with dexamethasone as a sample drugJournal of Drug Delivery Science and Technology

2006

Influence of aqueous diffusion layer on passive drug diffusion from aqueous cyclodextrin solutions through biological membranesPharmazie
Intranasal midazolam: A comparison of two delivery devices in human volunteersJournal of Pharmacy and Pharmacology
Comparison of topical 0.7% dexamethasone-cyclodextrin with 0.1% dexamethasone sodium phosphate for postcataract inflammationGraefe's Archive for Clinical and Experimental Ophthalmology
Development and evaluation of an artificial membrane for determination of drug availabilityInternational Journal of Pharmaceutics
The Stokes-Einstein equation and the physiological effects of vitreous surgeryActa Ophthalmologica Scandinavica
Assessment of mucoadhesion by a resonant mirror biosensorInternational Journal of Pharmaceutics
Determination of aqueous solubility by heating and equilibration: A technical noteAAPS PharmSciTech
Ocular powder: Dry topical formulations of timolol are well tolerated in rabbitsJournal of Ocular Pharmacology and Therapeutics
Investigation of soft long chain quaternary ammonium compounds as co-factors to enhance in vitro gene deliveryPharmazie
Determination of aqueous solubility by heating and equilibration: a technical note.AAPS PharmSciTech [electronic resource].

2005

Investigation of drug-cyclodextrin complexes by a phase-distribution method: Some theoretical and practical considerationsChemical and Pharmaceutical Bulletin
Evaluation of cyclodextrin solubilization of drugsInternational Journal of Pharmaceutics
Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: Formation of aggregates and higher-order complexesInternational Journal of Pharmaceutics
Hydrolysis kinetics and QSAR investigation of soft antimicrobial agentsJournal of Pharmacy and Pharmacology
Cyclodextrin solubilization of the antibacterial agents triclosan and triclocarban: Effect of ionization and polymersJournal of Inclusion Phenomena
Cyclodextrins in drug deliveryExpert Opinion on Drug Delivery
Cyclodextrin formulation of dorzolamide and its distribution in the eye after topical administrationJournal of Controlled Release

2004

Self-Association of Cyclodextrins and Cyclodextrin ComplexesJournal of Pharmaceutical Sciences
Preparation of solid drug/cyclodextrin complexes of acidic and basic drugsPharmazie
Applications of chemically-modified cyclodextrins: Use of hydroxypropyl-β-cyclodextrin as an enabling excipient for brain targeting, redox-based derivatives of estradiol: A review of preclinical and clinical findingsJournal of Drug Delivery Science and Technology
Synthesis and Characterization of Chitosan N-betainates Having Various Degrees of SubstitutionMacromolecules
The effects of water-soluble polymers on cyclodextrins and cyclodextrin solubilization of drugsJournal of Drug Delivery Science and Technology
Role of cyclodextrins in improving oral drug deliveryAmerican Journal of Drug Delivery
Marine lipids as building blocks for soft quaternary ammonium compounds and their antibacterial activityPharmazie

2003

Examination of 19F-NMR as a tool for investigation of drug-cyelodextrin complexesDrug Development and Industrial Pharmacy
Investigation and physicochemical characterization of vinpocetine- sulfobutyl ether β-cyclodextrin binary and ternary complexesChemical and Pharmaceutical Bulletin
The effects of organic salts on the cyclodextrin solubilization of drugsInternational Journal of Pharmaceutics
Soft antibacterial agentsCurrent Medicinal Chemistry
Soft antimicrobial agents: Synthesis and activity of labile environmentally friendly long chain quaternary ammonium compoundsJournal of Medicinal Chemistry
The effects of cyclodextrins on topical delivery of hydrocortisone: The aqueous diffusion layerS.T.P. Pharma Sciences
Sublingual delivery of 17β-estradiol from cyclodextrin containing tabletsPharmazie

2002

Cyclodextrins in eye drop formulationsJournal of Inclusion Phenomena
Mucoadhesive sustained drug delivery system based on cationic polymer and anionic cyclodextrin/triclosan complexJournal of Inclusion Phenomena
Self association and cyclodextrin solubilization of NSAIDsJournal of Inclusion Phenomena
Fish skin as a model membrane to study transmembrane drug delivery with cyclodextrinsJournal of Inclusion Phenomena
PrefaceJournal of Inclusion Phenomena
The effects of cyclodextrins on hydrocortisone permeability through semi-permeable membranesJournal of Inclusion Phenomena
Self-association and cyclodextrin solubilization of drugsJournal of Pharmaceutical Sciences
Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: Solubility, chemical and photochemical stabilityInternational Journal of Pharmaceutics
Buccal absorption of ergotamine tartrate using the bioadhesive tablet system in guinea-pigsInternational Journal of Pharmaceutics
Cyclodextrins in eye drop formulations: Enhanced topical delivery of corticosteroids to the eyeActa Ophthalmologica Scandinavica
The use of chemically modified cyclodextrins in the development of formulations for chemical delivery systemsPharmazie
Cyclodextrins and drug permeability through semi-permeable cellophane membranesInternational Journal of Pharmaceutics
Cyclodextrins and the biopharmaceutics classification system of drugsJournal of Inclusion Phenomena
Cycloserine fatty acid derivatives as prodrugs: Synthesis, degradation and in Vitro skin permeabilityChemical and Pharmaceutical Bulletin

2001

Cyclodextrin solubilization of benzodiazepines: Formulation of midazolam nasal sprayInternational Journal of Pharmaceutics
Cyclodextrins in topical drug formulations: Theory and practiceInternational Journal of Pharmaceutics
Sustained drug delivery system based on a cationic polymer and an anionic drug/cyclodextrin complexPharmazie
Intranasal administration of midazolam in a cyclodextrin based formulation: Bioavailability and clinical evaluation in humansPharmazie

2000

Dermal delivery of ETH-615, a zwitterionic drugDrug Development and Industrial Pharmacy
Marine lipids for prodrugs, soft compounds and other pharmaceutical applicationsPharmazie
Lipophilic metronidazole derivatives and their absorption through hairless mouse skinPharmazie
Methazolamide 1% in cyclodextrin solution lowers IOP in human ocular hypertensionInvestigative Ophthalmology and Visual Science

1999

Influence of cyclodextrins on the stability of the peptide salmon calcitonin in aqueous solutionInternational Journal of Pharmaceutics
Methods to enhance the complexation efficiency of cyclodextrinsS.T.P. Pharma Sciences
Soft drugs based on hydrocortisone: The inactive metabolite approach and its application to steroidal antiinflammatory agentsPharmaceutical Research
Synthesis of cyclic glycerol ether cyclodextrin derivatives and investigation of their binding properties with drugsJournal of Inclusion Phenomena
Pharmaceutical applications of β-CyclodextrinPharmaceutical Technology Europe
Cyclodextrins as permeation enhancers: Some theoretical evaluations and in vitro testingJournal of Controlled Release
Effect of cyclodextrins and polymers on triclosan availability and substantivity in toothpastes in vivoJournal of Pharmaceutical Sciences
Diacyl glyceryl ester prodrugs for slow release in the skin: Synthesis and in vitro degradation and absorption studies for naproxen derivativesPharmazie
Drug-cyclodextrin complexation in the presence of water-soluble polymers: Enhanced solubility and percutaneous transportACS Symposium Series
Pharmaceutical applications of β-cyclodextrinPharmaceutical Technology

1998

Effect of cod-liver oil extract on the buccal permeation of ergotamine tartrateProceedings of the Controlled Release Society
Cyclodextrins as co-enhancers in dermal and transdermal drug deliveryPharmazie
Cyclodextrins: New drug delivery systems in dermatologyInternational Journal of Dermatology
Aqueous hydrocortisone mouthwash solution: Clinical evaluationActa Odontologica Scandinavica
Cyclodextrin solubilization of ETH-615, a zwitterionic drugDrug Development and Industrial Pharmacy
Stabilisation of ionic drugs through complexation with non-ionic and ionic cyclodextrinsInternational Journal of Pharmaceutics
Increasing the cyclodextrin complexation of drugs and drug biovailability through addition of water-soluble polymersPharmazie
Co-administration of a water-soluble polymer increases the usefulness of cyclodextrins in solid oral dosage formsPharmaceutical Research
Effect of the cod-liver oil extract on the buccal permeation of ionized and nonionized forms of ergotamine using the keratinized epithelial-free membrane of hamster cheek pouch mucosaInternational Journal of Pharmaceutics
The effect of water-soluble polymers on the aqueous solubility and complexing abilities of β-cyclodextrinInternational Journal of Pharmaceutics
Fatty acid extract from cod-liver oil: Activity against herpes simplex virus and enhancement of transdermal delivery of acyclovir in-vitroPharmacy and Pharmacology Communications

1997

Formulation and testing of methazolamide cyclodextrin eye drop solutionsJournal of Controlled Release
Cyclodextrin solubilization of water-soluble drugs: Calcipotriol and EB-1089Pharmazie
Unsaturated glycerol monoethers as novel skin penetration enhancersPharmazie
Effect of cyclodextrins on topical drug delivery to the eyeDrug Development and Industrial Pharmacy
Effect of various marine lipids on transdermal drug delivery - in vitro evaluationBollettino Chimico Farmaceutico

1996

Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilizationJournal of Pharmaceutical Sciences
Effects of cyclodextrins and polymers on topical drug delivery to the eye - Evaluations in humansProceedings of the Controlled Release Society
Topically effective acetazolamide eye-drop solution in manPharmaceutical Sciences
The influence of water-soluble polymers and pH on hydroxypropyl-β-cyclodextrin complexation of drugsDrug Development and Industrial Pharmacy
Formulation and clinical evaluation of a hydrocortisone solution for the treatment of oral diseaseInternational Journal of Pharmaceutics
Potentiation of anticancer effects of microencapsulated carboplatin by hydroxypropyl α-cyclodextrinJournal of Controlled Release
Dexamethasone-cyclodextrin-polymer co-complexes in aqueous eye drops: Aqueous humor pharmacokinetics in humansInvestigative Ophthalmology and Visual Science
The effect of water-soluble polymers on aqueous solubility of drugsInternational Journal of Pharmaceutics
Design and in vivo testing of 17β-estradiol-HPβCD sublingual tabletsPharmazie
Effects of cyclodextrins and polymers on transdermal drug deliveryProceedings of the Controlled Release Society

1995

Formulation development for a zidovudine chemical delivery system 1. Parenteral dosage formsInternational Journal of Pharmaceutics
Improved acitretin delivery through hairless mouse skin by cyclodextrin complexationInternational Journal of Pharmaceutics
Formulation development for a zidovudine chemical delivery system 2. Towards oral and non-parenteral dosage formsInternational Journal of Pharmaceutics
Fatty acids from cod-liver oil as skin penetration enhancersPharmazie
Preparation, characterization, and anesthetic properties of 2- hydroxypropyl-β-cyclodextrin complexes of pregnanolone and pregnenolone in rat and mouseJournal of Pharmaceutical Sciences
The effect of polyvinylpyrrolidone on cyclodextrin complexation of hydrocortisone and its diffusion through hairless mouse skinInternational Journal of Pharmaceutics

1994

Topically effective ocular hypotensive acetazolamide and ethoxyzolamide formulations in rabbitsJournal of Pharmacy and Pharmacology
The effect of water-soluble polymers on drug-cyclodextrin complexationInternational Journal of Pharmaceutics
The influence of cyclodextrins on the stability of cephalotin and aztreonam in aqueous solutionsPharmazie
The influence of 2-hydroxypropyl-β-cyclodextrin on diffusion rates and transdermal delivery of hydrocortisoneDrug Development and Industrial Pharmacy
The pharmacokinetics and transdermal delivery of loteprednol etabonate and related soft steroidsAdvanced Drug Delivery Reviews
The effect of hydroxypropyl methylcellulose on the release of dexamethasone from aqueous 2-hydroxypropyl-β-cyclodextrin formulationsInternational Journal of Pharmaceutics
2-Hydroxypropyl-β-cyclodextrin in topical carbonic anhydrase inhibitor formulationsEuropean Journal of Pharmaceutical Sciences
The effect of polyvinylpyrrolidone and hydroxypropyl methylcellulose on HPβCD complexation of hydrocortisone and its permeability through hairless mouse skinEuropean Journal of Pharmaceutical Sciences
Effect of cyclodextrins on the degradation of cortisone acetate, oestradiol benzoate and prednicarbate in aqueous solutionS.T.P. Pharma Sciences

1993

Cyclodextrin complexation of NSAIDs: Physicochemical characteristicsEuropean Journal of Pharmaceutical Sciences
Topical delivery of acetazolamide for psoriasisActa Dermato-Venereologica
The effect of cyclodextrins on the solubility and stability of medroxyprogesterone acetate and megestrol acetate in aqueous solutionInternational Journal of Pharmaceutics

1992

Metabolism, distribution, and transdermal permeation of a soft corticosteroid, loteprednol etabonatePharmaceutical Research
Improved delivery through biological membranes. XLV. Synthesis, physical-chemical evaluation, and brain uptake studies of 2-chloroethyl nitrosourea delivery systemsPharmaceutical Research
Effect of various cyclodextrins on solution stability and dissolution rate of doxorubicin hydrochlorideInternational Journal of Pharmaceutics
The stability of aspartame in aqueous solutionsActa Pharmaceutica Nordica
Preparation and physical evaluation of microcapsules of hydrophilic drug-cyclodextrin complexesJournal of Microencapsulation
Interactions between preservatives and 2-hydroxypropyl-β-cyclodextrinDrug Development and Industrial Pharmacy
Degradation of tauromustine (TCNU) in aqueous solutionsActa Pharmaceutica Nordica
Estramustine: Hydrolysis, solubilization, and stabilization in aqueous solutionsInternational Journal of Pharmaceutics
Stabilizing effect of tris(hydroxymethyl)aminomethane on N-nitrosoureas in aqueous solutions [1]Journal of Pharmaceutical Sciences

1991

Solubilization and stabilization of a benzylpenicillin chemical delivery system by 2-hydroxypropyl-β-cyclodextrinPharmaceutical Research
Cyclodextrin-accelerated degradation of β-lactam antibiotics in aqueous solutionsInternational Journal of Pharmaceutics
Stabilization of aspartame by cyclodextrinsInternational Journal of Pharmaceutics
Solubilization and stabilization of drugs through cyclodextrin complexationActa Pharmaceutica Nordica
The effects of cyclodextrins on transdermal delivery of drugsEuropean Journal of Pharmaceutics and Biopharmaceutics
2-Hydroxypropyl-β-cyclodextrin: Properties and usage in pharmaceutical formulationsPZ Wissenschaft

1990

Comparative study on inclusion complexation of acetylsalicylic acid, cholecalciferol and melphalan with β- and γ-cyclodextrin and some of their derivativesActa Pharmaceutica Nordica
The effect of 2-hydroxypropyl-β-cyclodextrin on the simultaneous dissolution and degradation of chlorambucilInternational Journal of Pharmaceutics
Degradation of lomustine (CCNU) in aqueous solutionsInternational Journal of Pharmaceutics
Novel central nervous system targeted semisynthetic penicillinsDrug Design and Delivery
The effect of phosphine oxides on transdermal deliveryActa Pharmaceutica Nordica

1989

Effects of 2-hydroxypropyl-β-cyclodextrin on the aqueous solubility of drugs and transdermal delivery of 17β-estradiolActa Pharmaceutica Nordica
Effect of choline esters and oleic acid on the penetration of acyclovir, estradiol, hydrocortisone, nitroglycerin, retinoic acid and trifluorothymidine across hairles mouse skin in vitroActa Pharmaceutica Nordica
The effects of 2-hydroxypropyl-β-cyclodextrin on the solubility and stability of chlorambucil and melphalan in aqueous solutionInternational Journal of Pharmaceutics
Effect of oleic acid on diffusion of drugs through hairless mouse skinActa Pharmaceutica Nordica

1988

Improved delivery through biological membranes XXXI: Solubilization and stabilization of an estradiol chemical delivery system by modified β-cyclodextrinsJournal of Pharmaceutical Sciences

1987

The effect of vehicle additives on the transdermal delivery of nitroglycerinPharmaceutical Research
Trifluorothymidine: potential non-invasive diagnosis of herpes simplex infection using 19F nuclear magnetic resonance in a murine hepatitis modelJournal of Virological Methods

1985

The effect of ionization on partition coefficients and topical deliveryActa Pharmaceutica Suecica

1984

Soft drugs VI. The application of the inactive metabolite approach for design of soft β-blockersPharmaceutical Research
Synthesis and evaluation of novel lidocaine sulfur analogsInternational Journal of Pharmaceutics

1981

Improved delivery through biological membranes X: Percutaneous absorption and metabolism of methylsulfinylmethyl 2-acetoxybenzoate and related aspirin prodrugsJournal of Pharmaceutical Sciences
Improved delivery through biological membranes IX: Kinetics and mechanism of hydrolysis of methylsulfinylmethyl 2-acetoxybenzoate and related aspirin prodrugsJournal of Pharmaceutical Sciences
Improved delivery through biological membranes VIII: Design, synthesis, and in vivo testing of true prodrugs of aspirinJournal of Pharmaceutical Sciences

Keywords for Specialisation:

Bioavailability

Ophtalmic drug delivery